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Poly (2-Hydroxyethyl Methacrylate) Macroporous Cryogel for Extracorporeal Medical Devices

Received: 5 August 2015    Accepted: 11 August 2015    Published: 19 August 2015
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Abstract

Poly (2-hydroxyethyl methacrylate) PHEMA monolithic cryogels were synthesized by free radical polymerization at -12°C for 18 hours and produced spongy, elastic and macroporous gel matrix. Scanning Electron Microscopy (SEM) measured structural properties of PHEMA monolithic cryogel matrix to visualize pore morphology. Mechanical properties of PHEMA monolithic cryogel such as storage modulus, compressive modulus, and creep test were measured with Dynamic mechanical analyzer (DMA). The PHEMA monolithic cryogel matrix shows ~ 97% recovery after 70% compression of cryogel and has a compressive modulus of 1.8kPa to 8.5kPa.

Published in International Journal of Biomedical Materials Research (Volume 3, Issue 4)
DOI 10.11648/j.ijbmr.20150304.12
Page(s) 46-55
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Macroporous Cryogel, Poly (2-Hydroxyethyl Methacrylate), Mechanical Properties, Creep Test, Compressive Modulus

References
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Cite This Article
  • APA Style

    Wuraola Akande, Lyuba Mikhalovska, Stuart James, Sergey Mikhalovsky. (2015). Poly (2-Hydroxyethyl Methacrylate) Macroporous Cryogel for Extracorporeal Medical Devices. International Journal of Biomedical Materials Research, 3(4), 46-55. https://doi.org/10.11648/j.ijbmr.20150304.12

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    ACS Style

    Wuraola Akande; Lyuba Mikhalovska; Stuart James; Sergey Mikhalovsky. Poly (2-Hydroxyethyl Methacrylate) Macroporous Cryogel for Extracorporeal Medical Devices. Int. J. Biomed. Mater. Res. 2015, 3(4), 46-55. doi: 10.11648/j.ijbmr.20150304.12

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    AMA Style

    Wuraola Akande, Lyuba Mikhalovska, Stuart James, Sergey Mikhalovsky. Poly (2-Hydroxyethyl Methacrylate) Macroporous Cryogel for Extracorporeal Medical Devices. Int J Biomed Mater Res. 2015;3(4):46-55. doi: 10.11648/j.ijbmr.20150304.12

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  • @article{10.11648/j.ijbmr.20150304.12,
      author = {Wuraola Akande and Lyuba Mikhalovska and Stuart James and Sergey Mikhalovsky},
      title = {Poly (2-Hydroxyethyl Methacrylate) Macroporous Cryogel for Extracorporeal Medical Devices},
      journal = {International Journal of Biomedical Materials Research},
      volume = {3},
      number = {4},
      pages = {46-55},
      doi = {10.11648/j.ijbmr.20150304.12},
      url = {https://doi.org/10.11648/j.ijbmr.20150304.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20150304.12},
      abstract = {Poly (2-hydroxyethyl methacrylate) PHEMA monolithic cryogels were synthesized by free radical polymerization at -12°C for 18 hours and produced spongy, elastic and macroporous gel matrix. Scanning Electron Microscopy (SEM) measured structural properties of PHEMA monolithic cryogel matrix to visualize pore morphology. Mechanical properties of PHEMA monolithic cryogel such as storage modulus, compressive modulus, and creep test were measured with Dynamic mechanical analyzer (DMA). The PHEMA monolithic cryogel matrix shows ~ 97% recovery after 70% compression of cryogel and has a compressive modulus of 1.8kPa to 8.5kPa.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Poly (2-Hydroxyethyl Methacrylate) Macroporous Cryogel for Extracorporeal Medical Devices
    AU  - Wuraola Akande
    AU  - Lyuba Mikhalovska
    AU  - Stuart James
    AU  - Sergey Mikhalovsky
    Y1  - 2015/08/19
    PY  - 2015
    N1  - https://doi.org/10.11648/j.ijbmr.20150304.12
    DO  - 10.11648/j.ijbmr.20150304.12
    T2  - International Journal of Biomedical Materials Research
    JF  - International Journal of Biomedical Materials Research
    JO  - International Journal of Biomedical Materials Research
    SP  - 46
    EP  - 55
    PB  - Science Publishing Group
    SN  - 2330-7579
    UR  - https://doi.org/10.11648/j.ijbmr.20150304.12
    AB  - Poly (2-hydroxyethyl methacrylate) PHEMA monolithic cryogels were synthesized by free radical polymerization at -12°C for 18 hours and produced spongy, elastic and macroporous gel matrix. Scanning Electron Microscopy (SEM) measured structural properties of PHEMA monolithic cryogel matrix to visualize pore morphology. Mechanical properties of PHEMA monolithic cryogel such as storage modulus, compressive modulus, and creep test were measured with Dynamic mechanical analyzer (DMA). The PHEMA monolithic cryogel matrix shows ~ 97% recovery after 70% compression of cryogel and has a compressive modulus of 1.8kPa to 8.5kPa.
    VL  - 3
    IS  - 4
    ER  - 

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Author Information
  • Biomaterials and Medical Devices Research Group, School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK; Department of Clinical Pharmacy and Pharmacy Administration, Faculty of Pharmacy, University of Ibadan, Ibadan, Nigeria

  • Biomaterials and Medical Devices Research Group, School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UKBiomaterials and Medical Devices Research Group, School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK

  • Biomaterials and Medical Devices Research Group, School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK

  • Biomaterials and Medical Devices Research Group, School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK; School of Engineering, Nazarbayev University, Astana, Kazakhstan

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