Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria
International Journal of Biomedical Materials Research
Volume 4, Issue 3, December 2016, Pages: 58-62
Received: Aug. 19, 2016;
Accepted: Dec. 2, 2016;
Published: Jan. 4, 2017
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Hamza Sule, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria
Abdulhadi Sale Kumurya, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Bayero University, Kano, Nigeria
Ability of bacteria to withstand antibiotic therapy is often associated with resistance. Certain bacteria have the ability to produce some enzymes, like Beta–Lactamase, which confers resistance to some groups of antibiotics like penicillins and cephalosporins. The study focused on producers of these enzymes among uropathogens. A total of one hundred and forteen isolates (114) were screened, out of which seventy one 71 (62.3%) were found positive for the enzymes. Eschericia coli had the highest positivity rate 40 (56.3%). Followed by Klebsiella spp., Staphylococcus aureus, Staphylociccus saprophyticcus, Proteus mirabilis, and Pseudomonas aeruginosa with 15 (21.1%), 7 (10.0%), 5 (7.0%), 3 (4.2%), and 1 (1.4%) respectively. In the same vein, it was discovered that, isolates of females’ origin, produced more of the enzymes than those of their males counterpart. This was indicated by the production of the enzyme by at least one isolate in each of the species isolated from female samples while in males, some species did not even produce any of the enzymes. Age-wise distribution of the enzymes showed that, 21- 30, and 31-40 age groups had all the isolates producing the enzymes in varying frequencies. Only Pseudomonas aeruginosa that produced its enzyme outside these age groups. Isolates of females origin had more of the enzymes produced in all the species compared to those from males, with ratios of; 26:14, 11:4, 5:2, 3:2, 2:1, and 1:0 for, E coli, Klebsiella species, Staphylococcus aureus, Staphylococcus saprophyticus, Proteus mirabilis, and Pseudomonas aeruginosa respectively.
Abdulhadi Sale Kumurya,
Beta-Lactamase Production Among Uropathogens in Patients Attending Some Hospitals in Kano, Nigeria, International Journal of Biomedical Materials Research.
Vol. 4, No. 3,
2016, pp. 58-62.
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