Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism

Oussama Kamal; Tarik Eljaddi; Habib Mouadili; El Houssaine EL Atmani; Laurent Lebrun; Miloudi Hlaïbi

doi:doi:10.11648/j.ajche.20170504.11

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Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism

Oussama Kamal, Tarik Eljaddi, Habib Mouadili, El Houssaine EL Atmani, Laurent Lebrun, Miloudi Hlaïbi

Published in American Journal of Chemical Engineering (Volume 5, Issue 4)

Received: 15 April 2017 Accepted: 5 May 2017 Published: 21 June 2017

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Abstract

Transport of lysine acetylsalicylate (LAS) through supported liquid membrane was investigated using methyl cholate (MC) as extractive agent. Kinetic and thermodynamic models were developed, based on the interaction of the substrate LAS with the extractive agent T, and the diffusion of the formed entity (TS) through the membrane. The experimental results verify the models and enable the determination of macroscopic parameters (permeabilities (P) and initial fluxes (J₀)), as well as microscopic parameters (association constants (K_ass), and apparent diffusion coefficients (D^*)), relating to formed entity (TS) and its diffusion through the membrane organic phase. Parameters such as initial concentration of the substrate in the feed phase, pH of the feed and stripping phases and temperature of the extraction medium were studied. The results obtain indicate that the mechanism of the migration of LAS through the membrane organic phase cannot be a pure diffusion movement but it takes place by successive jumps from one site to another of the extractive agent, via interaction reactions with LAS.

Published in	American Journal of Chemical Engineering (Volume 5, Issue 4)
DOI	10.11648/j.ajche.20170504.11
Page(s)	49-55
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Facilitated Transport, Supported Liquid Membranes, Permeability, Flux, Activation Parameters

References

[1]	Park. K and Bavry. A. A, “Aspirin: its risks, benefits, and optimal use in preventing cardiovascular events”, Cleveland Clinic Journal of Medicine, vol. 80, no. 5, pp. 318-26. 2013.
[2]	Blair. B. D, Crago. J. P, Hedman. C. J and Klaper. R. D, “Pharmaceuticals and personal care products found in the Great Lakes above concentrations of environmental concern,” Chemosphere, vol. 93, no. 9, pp. 2116–2123. 2013.
[3]	Jiang. M, Yang. W, Zhang. Z, Yang. Z, and Wang. Y, “Adsorption of three pharmaceuticals on two magnetic ion-exchange resins,” Journal of Environmental Sciences, vol. 31, pp. 226–234, 2015.
[4]	Onesios-Barry. K. M, Berry. D, Proescher. J. B, Sivakumar. I. K. A, and Bouwer. E. J, “Removal of Pharmaceuticals and Personal Care Products during Water Recycling: Microbial Community Structure and Effects of Substrate Concentration,” Applied and Environmental Microbiology, vol. 80, no. 8, pp. 2440–2450, 2014.
[5]	Sadyrbaeva. T. Z, “Removal of chromium(VI) from aqueous solutions using a novel hybrid liquid membrane—electrodialysis process,” Chemical Engineering and Processing: Process Intensification, vol. 99, pp. 183–191, 2016.
[6]	Soniya. M and Muthuraman. G, “Comparative study between liquid–liquid extraction and bulk liquid membrane for the removal and recovery of methylene blue from wastewater,” Journal of Industrial and Engineering Chemistry, vol. 30, pp. 266–273, 2015.
[7]	Kocherginsky. N. M, Yang. Q, and Seelam. L, “Recent advances in supported liquid membrane technology,” Separation and Purification Technology, vol. 53, no. 2, pp. 171–177, 2007.
[8]	Yang. X. J, Fane. A. G and MacNaughton. S, “Removal and recovery of heavy metals from wastewaters by supported liquid membranes”, Water Science & Technology, vol. 42, no. 2, pp. 341-348, 2001.
[9]	Mahmoodi. R, T. Mohammadi and Moghadam. M. K. , “Separation of Cd(II) and Ni(II) ions by supported liquid membrane using D2EHPA/M2EHPA as mobile carrier”, Chemical Papers, vol. 68, no. 6, pp. 751-756, 2013.
[10]	Bhatluri. K. K, Manna. M. S, Ghoshal. A. K, and Saha. P, “Supported liquid membrane based removal of lead(II) and cadmium(II) from mixed feed: Conversion to solid waste by precipitation,” Journal of Hazardous Materials, vol. 299, pp. 504–512, 2015.
[11]	Swain. B, Mishra. C, Jeong. J, Lee. J, Hong. H. S and Pandey. B. D, “Separation of Co(II) and Li(I) with Cyanex 272 using hollow fiber supported liquid membrane: A comparison with flat sheet supported liquid membrane and dispersive solvent extraction process,” Chemical Engineering Journal, vol. 271, pp. 61–70, 2015.
[12]	Hao. Z, Vilt. M. E, Wang. Z, Zhang. W, and Winston Ho. W. S, “Supported liquid membranes with feed dispersion for recovery of Cephalexin,” Journal of Membrane Science, vol. 468, pp. 423–431, 2014.
[13]	Hassoune. H, Rhlalou. T, and Verchère. J-F, “Studies on sugars extraction across a supported liquid membrane: Complexation site of glucose and galactose with methyl cholate,” Journal of Membrane Science, vol. 315, no. 1–2, pp. 180–186, 2008.
[14]	Pirom. T, Sunsandee. N, Ramakul. P, Pancharoen. U, Nootong. K and Leepipatpiboon. N, “Separation of amoxicillin using trioctylmethylammonium chloride via a hollow fiber supported liquid membrane: Modeling and experimental investigation,” Journal of Industrial and Engineering Chemistry, vol. 23, pp. 109–118, 2015.
[15]	Kawasakia. J, Egashiraa. R, Kawaia. T, Haraa. H and Boyadzhiev. L, “Recovery of erythromycin by a liquid membrane”, Journal of Membrane Science, vol. 112, no. 2, 17, pp. 209–217, 1996.
[16]	Ishizu. H, Habaki. H and Kawasaki. J, “Permeation and concentration of compactin by a liquid membrane technique”, Journal of Membrane Science, vol. 213, no. 1–2, pp. 209-219, 2003.
[17]	Kouki. N, Tayeb. R, Zarrougui. R, and Dhahbi. M, “Transport of salicylic acid through supported liquid membrane based on ionic liquids,” Separation and Purification Technology, vol. 76, no. 1, pp. 8–14, 2010.
[18]	Kamal. O, Benlyamani. A, Serdaoui. F, Riri. M, Cherif. A, and Hlaïbi. M, “Stability Studies of Lysine Acetylsalicylate (Aspirin Derivative): Mechanisms of Hydrolysis,” Open Journal of Physical Chemistry, vol. 02, no. 02, pp. 81–87, 2012.
[19]	Hlaïbi. M, Tbeur. N, Benjjar. A, Kamal. O and Lebrun. L, “Carbohydrate–resorcinarene complexes involved in the facilitated transport of alditols across a supported liquid membrane”, Journal of Membrane Science, vol. 377, no. 1–2,, pp. 231–240, 2011.
[20]	Fontàs. C, Tayeb. R, Dhahbi. M, Gaudichet. E, Thominette. F, Roy. P, Steenkeste. K, Fontaine-Aupart. M, Tingry. S, Tronel-Peyroz. E and Seta. P, “Polymer inclusion membranes: The concept of fixed sites membrane revised”, Journal of Membrane Science, vol. 290, no. 1–2, pp. 62–72, 2007.
[21]	Kislik. S. V, “Principles and Application in Chemical Separations and Wastewater Treatment”, Liquid Membranes, pp. 1–15, 2010.
[22]	Benjjar. A, Eljaddi. T, Kamal. O, Touaj. K, Lebrun. L, and Hlaibi. M, “The development of new supported liquid membranes (SLMs) with agents: Methyl cholate and resorcinarene as carriers for the removal of dichromate ions (Cr₂O₇²⁻),” Journal of Environmental Chemical Engineering, vol. 2, no. 1, pp. 503–509, 2014.
[23]	Konczyk. J, Kozlowski. C, and Walkowiak. W, “Removal of chromium(III) from acidic aqueous solution by polymer inclusion membranes with D2EHPA and Aliquat 336,” Desalination, vol. 263, no. 1–3, pp. 211–216, 2010.
[24]	Touaj. K, Kamal. O, Atmani. El-H, Eljaddi. T, Lebrun. L and Hlaïbi. M, “Membrane processes for the facilitated extraction of disaccharide sugars: Parameters and mechanism”, Microporous and Mesoporous Materials, vol. 198, 2014, pp. 122–128.
[25]	Hor. M, Riad. A, Benjjar. A, Lebrun. L, and Hlaïbi. M, “Technique of supported liquid membranes (SLMs) for the facilitated transport of vanadium ions (VO₂⁺),” Desalination, vol. 255, no. 1–3, pp. 188–195, 2010.
[26]	Benjjar. A, Hor. M, Riri. M, Eljaddi. T, Kamal. O, Lebrun. L, and Hlaïbi. M, “A new supported liquid membrane (SLM) with methyl cholate for facilitated transport of dichromate ions from mineral acids: parameters and mechanism relating to the transport.”, Journal of Materials and Environmental Science, vol. 3, no. 5, pp. 826-839, 2012.

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APA Style

Oussama Kamal, Tarik Eljaddi, Habib Mouadili, El Houssaine EL Atmani, Laurent Lebrun, et al. (2017). Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism. American Journal of Chemical Engineering, 5(4), 49-55. https://doi.org/10.11648/j.ajche.20170504.11

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ACS Style

Oussama Kamal; Tarik Eljaddi; Habib Mouadili; El Houssaine EL Atmani; Laurent Lebrun, et al. Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism. Am. J. Chem. Eng. 2017, 5(4), 49-55. doi: 10.11648/j.ajche.20170504.11

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AMA Style

Oussama Kamal, Tarik Eljaddi, Habib Mouadili, El Houssaine EL Atmani, Laurent Lebrun, et al. Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism. Am J Chem Eng. 2017;5(4):49-55. doi: 10.11648/j.ajche.20170504.11

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@article{10.11648/j.ajche.20170504.11,
  author = {Oussama Kamal and Tarik Eljaddi and Habib Mouadili and El Houssaine EL Atmani and Laurent Lebrun and Miloudi Hlaïbi},
  title = {Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism},
  journal = {American Journal of Chemical Engineering},
  volume = {5},
  number = {4},
  pages = {49-55},
  doi = {10.11648/j.ajche.20170504.11},
  url = {https://doi.org/10.11648/j.ajche.20170504.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajche.20170504.11},
  abstract = {Transport of lysine acetylsalicylate (LAS) through supported liquid membrane was investigated using methyl cholate (MC) as extractive agent. Kinetic and thermodynamic models were developed, based on the interaction of the substrate LAS with the extractive agent T, and the diffusion of the formed entity (TS) through the membrane. The experimental results verify the models and enable the determination of macroscopic parameters (permeabilities (P) and initial fluxes (J0)), as well as microscopic parameters (association constants (Kass), and apparent diffusion coefficients (D*)), relating to formed entity (TS) and its diffusion through the membrane organic phase. Parameters such as initial concentration of the substrate in the feed phase, pH of the feed and stripping phases and temperature of the extraction medium were studied. The results obtain indicate that the mechanism of the migration of LAS through the membrane organic phase cannot be a pure diffusion movement but it takes place by successive jumps from one site to another of the extractive agent, via interaction reactions with LAS.},
 year = {2017}
}

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TY  - JOUR
T1  - Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism
AU  - Oussama Kamal
AU  - Tarik Eljaddi
AU  - Habib Mouadili
AU  - El Houssaine EL Atmani
AU  - Laurent Lebrun
AU  - Miloudi Hlaïbi
Y1  - 2017/06/21
PY  - 2017
N1  - https://doi.org/10.11648/j.ajche.20170504.11
DO  - 10.11648/j.ajche.20170504.11
T2  - American Journal of Chemical Engineering
JF  - American Journal of Chemical Engineering
JO  - American Journal of Chemical Engineering
SP  - 49
EP  - 55
PB  - Science Publishing Group
SN  - 2330-8613
UR  - https://doi.org/10.11648/j.ajche.20170504.11
AB  - Transport of lysine acetylsalicylate (LAS) through supported liquid membrane was investigated using methyl cholate (MC) as extractive agent. Kinetic and thermodynamic models were developed, based on the interaction of the substrate LAS with the extractive agent T, and the diffusion of the formed entity (TS) through the membrane. The experimental results verify the models and enable the determination of macroscopic parameters (permeabilities (P) and initial fluxes (J0)), as well as microscopic parameters (association constants (Kass), and apparent diffusion coefficients (D*)), relating to formed entity (TS) and its diffusion through the membrane organic phase. Parameters such as initial concentration of the substrate in the feed phase, pH of the feed and stripping phases and temperature of the extraction medium were studied. The results obtain indicate that the mechanism of the migration of LAS through the membrane organic phase cannot be a pure diffusion movement but it takes place by successive jumps from one site to another of the extractive agent, via interaction reactions with LAS.
VL  - 5
IS  - 4
ER  -

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Author Information

Oussama Kamal

Laboratory of Materials Engineering for the Environment and Valuation, Faculty of Sciences A?n Chock, University Hassan II, Casablanca, Morocco; Laboratory of Polymeres Biopolymeres Surfaces, Faculty des Sciences, University of Rouen, Mont-Saint-Aignan, France
Tarik Eljaddi

Laboratory of Materials Engineering for the Environment and Valuation, Faculty of Sciences A?n Chock, University Hassan II, Casablanca, Morocco
Habib Mouadili

Laboratory of Materials Engineering for the Environment and Valuation, Faculty of Sciences A?n Chock, University Hassan II, Casablanca, Morocco
El Houssaine EL Atmani

Laboratory of Materials Engineering for the Environment and Valuation, Faculty of Sciences A?n Chock, University Hassan II, Casablanca, Morocco
Laurent Lebrun

Laboratory of Polymeres Biopolymeres Surfaces, Faculty des Sciences, University of Rouen, Mont-Saint-Aignan, France
Miloudi Hlaïbi

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APA Style

Oussama Kamal, Tarik Eljaddi, Habib Mouadili, El Houssaine EL Atmani, Laurent Lebrun, et al. (2017). Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism. American Journal of Chemical Engineering, 5(4), 49-55. https://doi.org/10.11648/j.ajche.20170504.11

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ACS Style

Oussama Kamal; Tarik Eljaddi; Habib Mouadili; El Houssaine EL Atmani; Laurent Lebrun, et al. Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism. Am. J. Chem. Eng. 2017, 5(4), 49-55. doi: 10.11648/j.ajche.20170504.11

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AMA Style

Oussama Kamal, Tarik Eljaddi, Habib Mouadili, El Houssaine EL Atmani, Laurent Lebrun, et al. Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism. Am J Chem Eng. 2017;5(4):49-55. doi: 10.11648/j.ajche.20170504.11

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@article{10.11648/j.ajche.20170504.11,
  author = {Oussama Kamal and Tarik Eljaddi and Habib Mouadili and El Houssaine EL Atmani and Laurent Lebrun and Miloudi Hlaïbi},
  title = {Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism},
  journal = {American Journal of Chemical Engineering},
  volume = {5},
  number = {4},
  pages = {49-55},
  doi = {10.11648/j.ajche.20170504.11},
  url = {https://doi.org/10.11648/j.ajche.20170504.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajche.20170504.11},
  abstract = {Transport of lysine acetylsalicylate (LAS) through supported liquid membrane was investigated using methyl cholate (MC) as extractive agent. Kinetic and thermodynamic models were developed, based on the interaction of the substrate LAS with the extractive agent T, and the diffusion of the formed entity (TS) through the membrane. The experimental results verify the models and enable the determination of macroscopic parameters (permeabilities (P) and initial fluxes (J0)), as well as microscopic parameters (association constants (Kass), and apparent diffusion coefficients (D*)), relating to formed entity (TS) and its diffusion through the membrane organic phase. Parameters such as initial concentration of the substrate in the feed phase, pH of the feed and stripping phases and temperature of the extraction medium were studied. The results obtain indicate that the mechanism of the migration of LAS through the membrane organic phase cannot be a pure diffusion movement but it takes place by successive jumps from one site to another of the extractive agent, via interaction reactions with LAS.},
 year = {2017}
}

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TY  - JOUR
T1  - Facilitated Transport of Lysine Acetylsalicylate Through Supported Liquid Membrane Using Methyl Cholate as Carrier: Parameters and Mechanism
AU  - Oussama Kamal
AU  - Tarik Eljaddi
AU  - Habib Mouadili
AU  - El Houssaine EL Atmani
AU  - Laurent Lebrun
AU  - Miloudi Hlaïbi
Y1  - 2017/06/21
PY  - 2017
N1  - https://doi.org/10.11648/j.ajche.20170504.11
DO  - 10.11648/j.ajche.20170504.11
T2  - American Journal of Chemical Engineering
JF  - American Journal of Chemical Engineering
JO  - American Journal of Chemical Engineering
SP  - 49
EP  - 55
PB  - Science Publishing Group
SN  - 2330-8613
UR  - https://doi.org/10.11648/j.ajche.20170504.11
AB  - Transport of lysine acetylsalicylate (LAS) through supported liquid membrane was investigated using methyl cholate (MC) as extractive agent. Kinetic and thermodynamic models were developed, based on the interaction of the substrate LAS with the extractive agent T, and the diffusion of the formed entity (TS) through the membrane. The experimental results verify the models and enable the determination of macroscopic parameters (permeabilities (P) and initial fluxes (J0)), as well as microscopic parameters (association constants (Kass), and apparent diffusion coefficients (D*)), relating to formed entity (TS) and its diffusion through the membrane organic phase. Parameters such as initial concentration of the substrate in the feed phase, pH of the feed and stripping phases and temperature of the extraction medium were studied. The results obtain indicate that the mechanism of the migration of LAS through the membrane organic phase cannot be a pure diffusion movement but it takes place by successive jumps from one site to another of the extractive agent, via interaction reactions with LAS.
VL  - 5
IS  - 4
ER  -

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