American Journal of Chemical Engineering

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Reactive Chromatography: A Review of Process Technology

Received: 06 December 2018    Accepted: 29 January 2019    Published: 21 February 2019
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Abstract

Chemical Industries are primarily intended for conversion of raw materials into desired products. It develops new products for human lives. The challenge for chemical companies is to cut their costs. The chemical industries have high rate of technological change. Chemical industries use separate processes for converting raw material into product. Now day’s the technology that is adopted is reactive separation. In this technology, the emphasis is given on combining separate units in one single unit. Advantageous of this technology is like reducing energy use, increase efficiency etc. Reactive separation uses different techniques like Reactive Chromatography, Reactive Distillation and Reactive Extraction, Reactive Membrane Separation, Reactive Crystallization. Out of this, Reactive chromatography is a attractive alternative since it employs differences in adsorption - desorption of chemical reagents on external solid phase, which can also act as catalyst. It is possible to obtain high purity of product from this process, also downstream purification is reduced or even eliminated. Fixed bed reactor or simulated bed reactors are mainly used for this purpose. Many researchers have studied reactive chromatography. This review is focused in development in reactive chromatography processes.

DOI 10.11648/j.ajche.20190701.11
Published in American Journal of Chemical Engineering (Volume 7, Issue 1, January 2019)
Page(s) 1-6
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Reactive Separation, Reactive Chromatography, Fixed Bed Chromatography Reactor, Simulated Bed Chromatography Reactor

References
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[4] O. Jungmin, B. Sreedhar, M. Donaldson, T. Frank, “Transesterification of propylene glycol methyl ether in chromatographic reactors using anion exchange resin as a catalyst”, Journal of ChromatographyA, vol. 466, 2016, pp. 84 – 95.
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[10] D. Gelosa, M. Ramaioli, and G. Valente, “Chromatographic Reactors: Esterification of Glycerol with Acetic Acid Using Acidic Polymeric Resins”, Industrial Engineeering Chemistry Reserch, vol. 42, 2003, pp. 6536 – 6544.
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[13] S. Ali, “Kinetics of Catalytic Esterification of Propionic Acid with Different Alcohols over Amberlyst 15”, International Journal of Chemical Kinetics, vol. 41, no.6, 2008, pp. 432 – 448.
[14] V. Gyani and S. Mahajani, “Reactive Chromatography for the Synthesis of 2 - Ethylhexyl Acetate”, Seperation Science and Technology, vol. 43, 2008, pp. 2245 – 2268.
[15] C. Pereira, M. Zabka, V., Silva, A. Rodrigues, “A novel process for the ethyl lactate synthesis in a simulated moving bed reactor”, Chemical Engineering Science, vol. 64, 2009, pp. 3301 – 3310.
[16] S. Dakdouki, D. Villemin, N. bar, “Solid‐Phase Reactive Chromatography (SPRC): A New Methodology for Wittig and Horner - Emmons Reactions on a Column under Microwave Irradiation”, Europan Journal of Orgnic Chemistry, vol. 2010, no.2, pp. 333 - 337.
[17] D. Patel and. B. Saha, “Esterification reactions of acetic acid and n - hexanol were studied in batch and continuous chromatographic reactors in the presence of a gelular ion-exchange resin catalyst”, Industrial & Engineering Chemistry Reserch, vol. 51, no.37, 2012, pp. 11965 – 11974.
[18] B. Reddy, V. Gyani, and S. Mahajani, “Simulated Moving Bed Reactor for the Synthesis of 2-Ethylhexyl Acetate. Part II: Simulation Based Design”, Industrial & Engineering Chemistry Reserch, vol. 53, 2014, pp. 15811 – 15823.
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Author Information
  • Department of Chemical Engineering, Babasaheb Ambedkar Technological University, Lonere, India

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    Rajendra Bhaskar Bhandare. (2019). Reactive Chromatography: A Review of Process Technology. American Journal of Chemical Engineering, 7(1), 1-6. https://doi.org/10.11648/j.ajche.20190701.11

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    Rajendra Bhaskar Bhandare. Reactive Chromatography: A Review of Process Technology. Am. J. Chem. Eng. 2019, 7(1), 1-6. doi: 10.11648/j.ajche.20190701.11

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    Rajendra Bhaskar Bhandare. Reactive Chromatography: A Review of Process Technology. Am J Chem Eng. 2019;7(1):1-6. doi: 10.11648/j.ajche.20190701.11

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  • @article{10.11648/j.ajche.20190701.11,
      author = {Rajendra Bhaskar Bhandare},
      title = {Reactive Chromatography: A Review of Process Technology},
      journal = {American Journal of Chemical Engineering},
      volume = {7},
      number = {1},
      pages = {1-6},
      doi = {10.11648/j.ajche.20190701.11},
      url = {https://doi.org/10.11648/j.ajche.20190701.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajche.20190701.11},
      abstract = {Chemical Industries are primarily intended for conversion of raw materials into desired products. It develops new products for human lives. The challenge for chemical companies is to cut their costs. The chemical industries have high rate of technological change. Chemical industries use separate processes for converting raw material into product. Now day’s the technology that is adopted is reactive separation. In this technology, the emphasis is given on combining separate units in one single unit. Advantageous of this technology is like reducing energy use, increase efficiency etc. Reactive separation uses different techniques like Reactive Chromatography, Reactive Distillation and Reactive Extraction, Reactive Membrane Separation, Reactive Crystallization. Out of this, Reactive chromatography is a attractive alternative since it employs differences in adsorption - desorption of chemical reagents on external solid phase, which can also act as catalyst. It is possible to obtain high purity of product from this process, also downstream purification is reduced or even eliminated. Fixed bed reactor or simulated bed reactors are mainly used for this purpose. Many researchers have studied reactive chromatography. This review is focused in development in reactive chromatography processes.},
     year = {2019}
    }
    

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    AB  - Chemical Industries are primarily intended for conversion of raw materials into desired products. It develops new products for human lives. The challenge for chemical companies is to cut their costs. The chemical industries have high rate of technological change. Chemical industries use separate processes for converting raw material into product. Now day’s the technology that is adopted is reactive separation. In this technology, the emphasis is given on combining separate units in one single unit. Advantageous of this technology is like reducing energy use, increase efficiency etc. Reactive separation uses different techniques like Reactive Chromatography, Reactive Distillation and Reactive Extraction, Reactive Membrane Separation, Reactive Crystallization. Out of this, Reactive chromatography is a attractive alternative since it employs differences in adsorption - desorption of chemical reagents on external solid phase, which can also act as catalyst. It is possible to obtain high purity of product from this process, also downstream purification is reduced or even eliminated. Fixed bed reactor or simulated bed reactors are mainly used for this purpose. Many researchers have studied reactive chromatography. This review is focused in development in reactive chromatography processes.
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