Modeling of an Actif Cyclic Electromagnetic Effect on Hemozoin for Malaria Diagnosis Computerized Electromagnetic Effect on Hemozoin for Malaria Diagnosis
American Journal of Electromagnetics and Applications
Volume 6, Issue 1, June 2018, Pages: 28-34
Received: May 14, 2018;
Accepted: Jun. 21, 2018;
Published: Jul. 17, 2018
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Walvede Biziya Deli, University of Ngaoundere, Electrical and Electronics Engineering Laboratory, Ngaoundere, Cameroon
Ntsama Eloundou Pascal, University of Ngaoundere, Electrical and Electronics Engineering Laboratory, Ngaoundere, Cameroon
Talla Emmanuel, University of Ngaoundere, Electrical and Electronics Engineering Laboratory, Ngaoundere, Cameroon
Kuitche Alexis, University of Ngaoundere, Electrical and Electronics Engineering Laboratory, Ngaoundere, Cameroon
In this work we present the heat generated by the super magnetic particle, the waste prevent from the plasmodium degradation. The hemozoin behaviour due to electromagnetic field applied on it will be used as a sensitive method for malaria diagnosis. Hemozoin presents its self in the form of a crystal and which constitutes a pigment synthesised by the malaria parasite with the aim of annihilating the toxic effect ofhematine. In effect, after contamination the plasmodium dwells inside the red blood cells of the host so as to feed itself with the amino-acids obtained by degradation of hemoglobin. But during this “meal” the parasite liberates a waste product in the form of a complex made of porphyrin and iron. In order to prevent that noxious effect, the plasmodium polymerizes the complexes of porphyrin inside a digestive vacuole to finally produce a crystal of a hemozoin not toxic for him. This particle is previously paramagnetic because of the presence of iron in the red blood cells. This paper proposes the modeling of magnetic field effect of hemozoin for malaria detection. The potential effect of the cyclically activated magnetic field was modeled using a thermodynamic framework. Then at the end, generation and diffusion of heat due to the presence of constant cyclically magnetic field have been determined. These to prove how the pull or push forces between the particles of Hemozoin are demonstrated by producing the heat. The energy inside the particle is also taken into consideration in the cell while doing the diagnosis of malaria.
Walvede Biziya Deli,
Ntsama Eloundou Pascal,
Modeling of an Actif Cyclic Electromagnetic Effect on Hemozoin for Malaria Diagnosis Computerized Electromagnetic Effect on Hemozoin for Malaria Diagnosis, American Journal of Electromagnetics and Applications.
Vol. 6, No. 1,
2018, pp. 28-34.
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Wernig F. and Xu Q 2002, Mechanical stress -induced apoptosis in the cardiovascular systemprogress in Biological and Moluclar Biology, 78(2), pp. 105-137.
Hayward, R.., Saliba, K. J., and Kirk, K. (2006) The pH of the digestive vacuole of theplasmodium falciparum is not associated with chlorquine resistance, J CellSci119, 1016-1025.
Sullivan DJ (December 2002). "Theories on malarial pigment formation and quinolineaction". Int J Parasitol 32 (13): 1645–53.
Yoed Rabin 2002, Cancer Treatment by Electromagnetic Activated Nanoheaters. Department of Mechanical Engineering.
Robin D. Powell, Colonel Willam D. Tigertt, 1968, Drug resistance of parasite causing Human malaria.
Solomon O. Abiola, 2012 Helmholtz Coil Design for Non-Invasive Detection and Apoptosis of Breast Cancer and Malaria Parsites, via Fe2O3, F e3O4 Nanoparticles and Hemin.
http://en.wikipedia.org/wiki/ Hysteresis, November 2017.
https://www.google.com/ur source,October 2007.
Q A Pankhurst, J Connolly, S K Jones and J Dobson, 2003 “Applications of magnetic nanoparticles in biomedicine’’.
L. Rast and J. G. Harrison, 2010, “Computatiçonal Modeling of Electromagnetically Induced Heatinof Magnetic Nanoparticle Materials for Hyperthermic Cancer Treatment”, Department of Physics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
C. Phatak, R. Pokharel, M. Beleggia, M. De Graef, 2011, On the magnetostatics of chains of magnetic nanoparticles.
Richard Fitzpatrick, 2008, Classical Electromagnetism: An intermediate level course
Kannan M. Krishnan, 2016, Biomedical Nanomagnetics: A Spin through Possibilities in Imaging, Diagnostics, and Therapy.
Henry C. Lai1 and Narendra P. Singh2016, Department of Bioengineering, University of Washington, Seattle, WA 98195-5061, USA.
Olivia April 2011, Difference between oscillation and vibration
A.-H. Lu, E. L. Salabas and F. Schüth, Angew. Chem., Int. Ed., 2007, 46, 1222–1244.
An-Hui Lu; E. L. Salabas, and Ferdi Schth (2007). Angew. Chem. Int. Ed. 46: 1222–1244.
Wang X. et al, 2017, Application of Nanotechnology in Cancer Therapy and Imaging.
Joerg Lehmann and Brita Lehmann 2016, Nanoparticle Thermotherapy: A New Approach in Cancer Therapy.
KUMIKO SATU, January 2018 (AIST), A new diagnostic technology for malaria.
Modélisation et simulation en épidémiologie G. Sallet INRIA & IRD 2010.
Geraldine TELLIER, septembre 2015, Etudes moléculaires et fonctionnelles de deux régulateurs de la rotéine phosphatase de type 1 chez Plasmodium falciparum: I2 et eIF2β.
MN Wogu 2018, Evaluating Malaria prevalence using Clinical Diagnosis.