Over the past 30 years DNA has been assembled into a plethora of structures by design, based on its reliable base pairing properties. As a result, many applications of DNA nanotechnology are emerging. Here, we review recent advances in the use of self-assembled DNA nanostructures as sensors. In particular, we focus on how defined nanostructures, such as rigid DNA tetrahedra, provide an advantage over traditional nanosensors consisting of arrays of single-stranded DNA. We also explore advances in DNA origami that have resulted in consistent detection of single molecules.
Karina M. M. Carneiro,
Andrea A. Greschner,
Recent Advances in Self-Assembled DNA Nanosensors, American Journal of Nano Research and Applications. Special Issue:Nanomaterials and Nanosensors for Chemical and Biological Detection.
Vol. 3, No. 1-1,
2015, pp. 1-7.
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