Isotopic Abundance Ratio Analysis of 1,2,3-Trimethoxybenzene (TMB) After Biofield Energy Treatment (The Trivedi Effect®) Using Gas Chromatography-Mass Spectrometry
American Journal of Applied Chemistry
Volume 4, Issue 4, August 2016, Pages: 132-140
Received: May 10, 2016; Accepted: Jun. 25, 2016; Published: Jul. 15, 2016
Views 2420      Downloads 101
Authors
Mahendra Kumar Trivedi, Trivedi Global Inc., Henderson, Nevada, USA
Alice Branton, Trivedi Global Inc., Henderson, Nevada, USA
Dahryn Trivedi, Trivedi Global Inc., Henderson, Nevada, USA
Gopal Nayak, Trivedi Global Inc., Henderson, Nevada, USA
Parthasarathi Panda, Trivedi Science Research Laboratory Pvt. Ltd., Bhopal, Madhya Pradesh, India
Snehasis Jana, Trivedi Science Research Laboratory Pvt. Ltd., Bhopal, Madhya Pradesh, India
Article Tools
Follow on us
Abstract
1,2,3-Trimethoxybenzene (TMB) is one of the most versatile chemical used for the synthesis of several pharmaceuticals, dyes, polymers, organic compounds, etc. The stable isotope ratio analysis has increased attention day-by-days in several fields such as agricultural, food authenticity, biochemistry, medical research, etc. The current study was aimed to evaluate the effect of the biofield energy treatment on the isotopic abundance ratios of 13C/12C or 2H/1H or 17O/16O (PM+1/PM) and 18O/16O (PM+2/PM) in TMB using Gas chromatography - mass spectrometry (GC-MS) technique. TMB was divided into two parts - one part was denoted as control and another part was referred as biofield energy treated sample that was received through Mr. Trivediꞌs unique biofield energy (The Trivedi Effect®). The GC-MS of the biofield treated TMB was characterized at different time intervals considered as T1, T2, T3, and T4 to examine the impact of the biofield energy treatment on isotopic abundance ratio with respect to the time. The GC-MS spectra of the both control and biofield treated TMB exhibited the presence of molecular ion peak [M+] at m/z 168 (calculated 168.08 for C9H12O3) along with similar pattern of fragmentation. The relative peak intensities of the fragmented ions in the biofield treated TMB, particularly at T2 and T3 was altered from the control sample. The isotopic abundance ratio analysis in the biofield treated TMB exhibited that the isotopic abundance ratio of PM+1/PM in the biofield treated TMB at T2 and T3 was significantly enhanced by 128.13 and 117.99%, respectively with respect to the control sample. Consequently, the percentage change in isotopic abundance ratio of PM+2/PM+1 was significantly increased in the biofield treated TMB at T2 and T3 by 125.93 and 116.67%, respectively as compared with the control TMB. The isotopic abundance ratios (PM+1/PM and PM+2/PM) in the biofield treated TMB at T1 and T4 was altered with respect to the control TMB. In summary, 13C, 2H, and 17O contributions from (C9H12O3)+ to m/z 169 and 18O contribution from (C9H12O3)+ to m/z 170 for the biofield treated TMB, particularly at T2 and T3 were significantly improved and biofield treated TMB might exhibit changed isotope effects as compared to the control sample. The biofield treated TMB might assist to develop new chemicals and pharmaceuticals through using its kinetic isotope effects like understanding the reaction mechanism, the enzymatic transition state and all aspects of enzyme mechanisms.
Keywords
Biofield Energy Treatment, The Trivedi Effect®, 1,2,3-Trimethoxybenzene, Gas Chromatograph - Mass Spectrometry, Isotopic Abundance Ratio, Isotope Effects, Kinetic Isotope Effect
To cite this article
Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Parthasarathi Panda, Snehasis Jana, Isotopic Abundance Ratio Analysis of 1,2,3-Trimethoxybenzene (TMB) After Biofield Energy Treatment (The Trivedi Effect®) Using Gas Chromatography-Mass Spectrometry, American Journal of Applied Chemistry. Vol. 4, No. 4, 2016, pp. 132-140. doi: 10.11648/j.ajac.20160404.13
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Gannes LZ, Martinez del Rio C, Koch P (1998) Natural abundance variations in stable isotopes and their potential uses in animal physiological ecology. Comp Biochem Physiol A Mol Intergr Physiol 119: 725-737.
[2]
Schellekens RC, Stellaard F, Woerdenbag HJ, Frijlink HW, Kosterink JG (2011) Applications of stable isotopes in clinical pharmacology. Br J Clin Pharmacol 72: 879-897.
[3]
Muccio Z, Jackson GP (2009) Isotope ratio mass spectrometry. Analyst 134: 213–222.
[4]
http://www.eolss.net/sample-chapters/c06/e6-104-01-00.pdf
[5]
www-naweb.iaea.org/napc/ih/documents/global_cycle/.../cht_i_03.pd
[6]
Asperger S (2003) Chemical Kinetics and Inorganic Reaction Mechanisms Springer science + Business media, New York.
[7]
Smith RM (2004) Understanding Mass Spectra: A Basic Approach, Second Edition, John Wiley & Sons, Inc, ISBN 0-471-42949-X.
[8]
Jürgen H. Gross Mass Spectrometry: A Textbook; Springer: Berlin, 2nd Edn., 2004.
[9]
Vanhaecke F, Kyser K (2012) Isotopic composition of the elements In Isotopic Analysis: Fundamentals and applications using ICP-MS, 1st Edn., Edited by Vanhaecke F, Degryse P, Wiley-VCH GmbH & Co. KGaA, Weinheim.
[10]
Meier-Augenstein W (1999) Applied gas chromatography coupled to isotope ratio mass spectrometry. J Chromatogr A 842: 351-371.
[11]
Raymond E. March, John F. J. Todd Practical Aspects of Trapped Ion Mass Spectrometry, Volume IV: Theory and instrumentation (2010) CRC press, Taylor and Francis Group, Boca Raton.
[12]
Skoog DA, Holler FJ, Crouch SR (2007) Principles of instrument analysis, 6th Edn., Thomson Brooks/Cole, Australia.
[13]
http://www.sepscience.com/Information/Archive/MS-Solutions/254-/MS-Solutions-5-The-Role-of-Isotope-Peak-Intensities-Obtained-Using-Mass-Spectrometry-in-Determining-an-Elemental-Composition-Part-1
[14]
https://www.unido.org/fileadmin/user_media/Services/Environmental_Management/Stockholm_Convention/POPs/DLWKSP_Part2.pdf
[15]
Trivedi MK, Tallapragada RM, Branton A, Trivedi D, Nayak G, Mishra RK, Jana S (2015) Physical, thermal and spectral properties of biofield treated 1,2,3-Trimethoxybenzene. J Develop Drugs 4: 136.
[16]
http://www.chemicalland21.com/lifescience/phar/1,3,5-trimethoxybenzene.htm
[17]
Yoshida J-I (2008) Flash chemistry: Fast organic synthesis in microsystems, John Wiley & Sons, Ltd., UK.
[18]
Diederich F, Stang PJ (2000) Templated Organic Synthesis, Wiley-VCH GmbH & Co. KGaA, Weinheim
[19]
Schafer Jr. EW, Bowles Jr. WA, Hurlbut J (1983) The acute oral toxicity, repellency, and hazard potential of 998 chemicals to one or more species of wild and domestic birds. Arch Environm Contam Toxicol 12: 355-382.
[20]
Potential for human exposure. Benzene. Accessed on: 29 September 2015. http://www.atsdr.cdc.gov/toxprofiles/tp3-c6.pdf
[21]
http://www.colorado.edu/philosophy/vstenger/Medicine/Biofield.html
[22]
Rubik B (2002) The biofield hypothesis: Its biophysical basis and role in medicine. J Altern Complement Med 8: 703-717.
[23]
Klupenger MR (2015) An investigation into the effect of human intention on the weather, Energy Medicine University, Sausalito, California, USA.
[24]
Trivedi MK, Branton A, Trivedi D, Nayak G, Singh R, Jana S (2016) Characterization of physical, thermal and spectroscopic properties of bio field treated ortho-toluic acid. J O Heterocyclics 106: 21-28.
[25]
Jana S, Trivedi MK, Branton A, Trivedi D, Nayak G, Saikia G (2015) Physical and structural characterization of biofield energy treated carbazole. Pharm Anal Acta 6: 435.
[26]
Trivedi MK, Branton A, Trivedi D, Nayak G, Singh R, Jana S (2015) Studies on physicochemical properties of biofield treated 2, 4-dichlorophenol. American Journal of Environmental Protection 4: 292-299.
[27]
Trivedi MK, Branton A, Trivedi D, Nayak G, Saikia G, Jana S (2015) Physical and structural characterization of biofield treated imidazole derivatives. Nat Prod Chem Res 3: 187.
[28]
Trivedi MK, Branton A, Trivedi D, Nayak G, Bairwa K, Jana S (2015) Spectroscopic characterization of disulfiram and nicotinic acid after biofield treatment. J Anal Bioanal Tech 6: 265.
[29]
Trivedi MK, Tallapragada RM, Branton A, Trivedi D, Nayak G, Latiyal O, Jana S (2015) Evaluation of biofield energy treatment on physical and thermal characteristics of selenium powder. Journal of Food and Nutrition Sciences. 3: 223-228.
[30]
Trivedi MK, Tallapragada RM, Branton A, Trivedi D, Nayak G, Latiyal O, Jana S (2015) Physicochemical and atomic characterization of silver powder after biofield treatment. J Bioengineer & Biomedical Sci 5: 165.
[31]
Trivedi MK, Nayak G, Patil S, Tallapragada RM, Latiyal O, Jana S (2015) Evaluation of biofield treatment on physical and structural properties of bronze powder. Adv Automob Eng 4: 119.
[32]
Trivedi MK, Branton A, Trivedi D, Nayak G, Gangwar M, Jana S (2015) Evaluation of vegetative growth parameters in biofield treated bottle gourd (Lagenaria siceraria) and okra (Abelmoschus esculentus). International Journal of Nutrition and Food Sciences 4: 688-694.
[33]
Trivedi MK, Branton A, Trivedi D, Nayak G, Mondal SC, Jana S (2015) Evaluation of plant growth, yield and yield attributes of biofield energy treated mustard (Brassica juncea) and chick pea (Cicer arietinum) seeds. Agriculture, Forestry and Fisheries 4: 291-295.
[34]
Trivedi MK, Patil S, Shettigar H, Gangwar M, Jana S (2015) In Vitro evaluation of biofield treatment on cancer biomarkers involved in endometrial and prostate cancer cell lines. J Cancer Sci Ther 7: 253-257.
[35]
Trivedi MK, Patil S, Shettigar H, Mondal SC, Jana S (2015) Evaluation of biofield modality on viral load of Hepatitis B and C viruses. J Antivir Antiretrovir 7: 083-088.
[36]
Trivedi MK, Branton A, Trivedi D, Nayak G, Mondal SC, Jana S (2015) Antibiogram, biochemical reactions and biotyping of biofield treated Providencia rettgeri. American Journal of Health Research 3: 344-351.
[37]
Trivedi MK, Branton A, Trivedi D, Nayak G, Shettigar H, Gangwar M, Jana S (2015) Characterization of antimicrobial susceptibility profile of biofield treated multidrug-resistant Klebsiella oxytoca. Appli Micro Open Access 1: 101.
[38]
Trivedi MK, Branton A, Trivedi D, Nayak G, Gangwar M, Jana S (2015) Antibiogram typing of biofield treated multidrug resistant strains of Staphylococcus species. American Journal of Life Sciences 3: 369-374.
[39]
Trivedi MK, Branton A, Trivedi D, Nayak G, Saikia G, Jana S (2015) Thermal, spectroscopic and chemical characterization of biofield energy treated anisole. Organic Chem Curr Res 4: 152.
[40]
Trivedi MK, Branton A, Trivedi D, Nayak G, Saikia G, Jana S (2016) Determination of isotopic abundance of 2H, 13C, 18O, and 37Cl in biofield energy treated dichlorophenol isomers. Science Journal of Analytical Chemistry 4: 1-6.
[41]
Trivedi MK, Branton A, Trivedi D, Nayak G, Saikia G, Jana S (2015) Mass spectrometry analysis of isotopic abundance of 13C, 2H, or 15N in biofield energy treated aminopyridine derivatives. American Journal of Physical Chemistry 4: 65-70.
[42]
Trivedi MK, Branton A, Trivedi D, Nayak G, Saikia G, Jana S (2015) Influence of biofield energy treatment on isotopic abundance ratio in aniline derivatives. Mod Chem appl 3: 168.
[43]
http://www.ionsource.com/Card/Mass/mass.htm
[44]
Meija J, Coplen TB, Berglund M, Brand WA, De Bievre P, Groning M, Holden NE, Irrgeher J, Loss RD, Walczyk T, Prohaska T (2016) Isotopic compositions of the elements 2013 (IUPAC technical Report). Pure Appl Chem 88: 293-306.
[45]
http://webbook.nist.gov/cgi/cbook.cgi?ID=C108463&Mask=200
[46]
Balantekin AB (2013) Neutrinos and rare isotopes Journal of Physics: Conference Series 445 012022.
[47]
Domogatskii GV, Nadezhin DK (1978) Neutrino production of bypassed isotopes, and the possible role of neutrinos in nucleosynthesis. Astron Zh 55: 516-530.
[48]
Rogers, M (1986) "Science of Unitary Human Beings." In V. M. Malinski (ed.) Explorations of Martha Rogers' Science of Unitary Human Beings. Norwark: Appleton Century Crofts.
[49]
Jenkins L (2011) Healing in the present moment. ISBN 978-1-257-77329-9.
[50]
de Climont J (2016) The worldwide list of dissident scientists, ISBN 978-2-9024-2517-4.
[51]
Carr Jr. RW, Walters WD (1966) The hydrogen isotope effect in the thermal decomposition of cyclobutane, J Am Chem Soc 88: 884-887.
[52]
Lomas JS, Thorne MP (1982) Structure and isotope effects upon the thermal decomposition of carbamates of highly congested tertiary alcohols. J Chem Soc, Perkin Trans 2 221-226.
[53]
Makhatadze GI, Clore GM, Gronenborn AM (1995) Solvent isotope effect and protein stability. Nat Struct Biol 2: 852 - 855.
[54]
Schramm VL (1998) Enzymatic transition states and transition state analog design. Annu Rev Biochem 67: 693-720.
[55]
Cleland WW (2003) The use of isotope effects to determine enzyme mechanisms. J Biol Chem 278: 51975-84.
ADDRESS
Science Publishing Group
548 FASHION AVENUE
NEW YORK, NY 10018
U.S.A.
Tel: (001)347-688-8931