American Journal of Civil Engineering

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Rules Regulating the Change in Physiological Parameters of Rats Under Simulated Microgravity and Different Ambient Temperatures

Received: 18 January 2019    Accepted:     Published: 28 April 2019
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Abstract

To investigate the rules regulating changes in mean chest temperature (MCT), mean rectal temperature (MRT) and mean body weight (MW)in rats at simulated microgravity and different ambient temperatures (ATs). The −30º rat tail suspension (TS) method was used to simulate microgravity over a 7 day period at 18°C, 20°C, 23°C and 26°C AT through comparison between the TS group and control group. Each group contained six male SD rats (including one verification rat). MCT and MRT of TS group rats increased at all four levels of AT. MCT and MRT reached maximum growth rates of 0.315 and 0.118 at ATs of 20°C and 23°C, respectively. MW was reduced at ATs of 20°C and 23°C, whereas it increased at 18°C and 26°C AT in the TS group. The rates of changes of MCT, MRT and MW at different ATs were analyzed using linear regression analysis for both the control (Equation 1) and TS (Equation 2) groups. Using A new equation (Equation 3) without the influence of other factors was derived after Equation 1 minus Equation 2 to derive. The result shows that the coefficients of Equation 3 are different under the four ATs. TS and AT have coupling effects on the MCT, MRT and MW of rats.

DOI 10.11648/j.ajce.20190701.15
Published in American Journal of Civil Engineering (Volume 7, Issue 1, January 2019)
Page(s) 27-34
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Tail Suspended Rats, Mean Chest Temperature, Mean Rectal Temperature, Mean Body Weight, Ambient Temperature

References
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Cite This Article
  • APA Style

    Jie Qian, Gengxin Xie, Jie Zheng, Bo Duan, Yajun Cao, et al. (2019). Rules Regulating the Change in Physiological Parameters of Rats Under Simulated Microgravity and Different Ambient Temperatures. American Journal of Civil Engineering, 7(1), 27-34. https://doi.org/10.11648/j.ajce.20190701.15

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    ACS Style

    Jie Qian; Gengxin Xie; Jie Zheng; Bo Duan; Yajun Cao, et al. Rules Regulating the Change in Physiological Parameters of Rats Under Simulated Microgravity and Different Ambient Temperatures. Am. J. Civ. Eng. 2019, 7(1), 27-34. doi: 10.11648/j.ajce.20190701.15

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    AMA Style

    Jie Qian, Gengxin Xie, Jie Zheng, Bo Duan, Yajun Cao, et al. Rules Regulating the Change in Physiological Parameters of Rats Under Simulated Microgravity and Different Ambient Temperatures. Am J Civ Eng. 2019;7(1):27-34. doi: 10.11648/j.ajce.20190701.15

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  • @article{10.11648/j.ajce.20190701.15,
      author = {Jie Qian and Gengxin Xie and Jie Zheng and Bo Duan and Yajun Cao and Xi Wang and Fengjie Li and Changpeng Hu},
      title = {Rules Regulating the Change in Physiological Parameters of Rats Under Simulated Microgravity and Different Ambient Temperatures},
      journal = {American Journal of Civil Engineering},
      volume = {7},
      number = {1},
      pages = {27-34},
      doi = {10.11648/j.ajce.20190701.15},
      url = {https://doi.org/10.11648/j.ajce.20190701.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajce.20190701.15},
      abstract = {To investigate the rules regulating changes in mean chest temperature (MCT), mean rectal temperature (MRT) and mean body weight (MW)in rats at simulated microgravity and different ambient temperatures (ATs). The −30º rat tail suspension (TS) method was used to simulate microgravity over a 7 day period at 18°C, 20°C, 23°C and 26°C AT through comparison between the TS group and control group. Each group contained six male SD rats (including one verification rat). MCT and MRT of TS group rats increased at all four levels of AT. MCT and MRT reached maximum growth rates of 0.315 and 0.118 at ATs of 20°C and 23°C, respectively. MW was reduced at ATs of 20°C and 23°C, whereas it increased at 18°C and 26°C AT in the TS group. The rates of changes of MCT, MRT and MW at different ATs were analyzed using linear regression analysis for both the control (Equation 1) and TS (Equation 2) groups. Using A new equation (Equation 3) without the influence of other factors was derived after Equation 1 minus Equation 2 to derive. The result shows that the coefficients of Equation 3 are different under the four ATs. TS and AT have coupling effects on the MCT, MRT and MW of rats.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Rules Regulating the Change in Physiological Parameters of Rats Under Simulated Microgravity and Different Ambient Temperatures
    AU  - Jie Qian
    AU  - Gengxin Xie
    AU  - Jie Zheng
    AU  - Bo Duan
    AU  - Yajun Cao
    AU  - Xi Wang
    AU  - Fengjie Li
    AU  - Changpeng Hu
    Y1  - 2019/04/28
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ajce.20190701.15
    DO  - 10.11648/j.ajce.20190701.15
    T2  - American Journal of Civil Engineering
    JF  - American Journal of Civil Engineering
    JO  - American Journal of Civil Engineering
    SP  - 27
    EP  - 34
    PB  - Science Publishing Group
    SN  - 2330-8737
    UR  - https://doi.org/10.11648/j.ajce.20190701.15
    AB  - To investigate the rules regulating changes in mean chest temperature (MCT), mean rectal temperature (MRT) and mean body weight (MW)in rats at simulated microgravity and different ambient temperatures (ATs). The −30º rat tail suspension (TS) method was used to simulate microgravity over a 7 day period at 18°C, 20°C, 23°C and 26°C AT through comparison between the TS group and control group. Each group contained six male SD rats (including one verification rat). MCT and MRT of TS group rats increased at all four levels of AT. MCT and MRT reached maximum growth rates of 0.315 and 0.118 at ATs of 20°C and 23°C, respectively. MW was reduced at ATs of 20°C and 23°C, whereas it increased at 18°C and 26°C AT in the TS group. The rates of changes of MCT, MRT and MW at different ATs were analyzed using linear regression analysis for both the control (Equation 1) and TS (Equation 2) groups. Using A new equation (Equation 3) without the influence of other factors was derived after Equation 1 minus Equation 2 to derive. The result shows that the coefficients of Equation 3 are different under the four ATs. TS and AT have coupling effects on the MCT, MRT and MW of rats.
    VL  - 7
    IS  - 1
    ER  - 

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Author Information
  • School of Urban Construction and Environmental Engineering, Chongqing University, Chongqing, China; Center of Space Exploration, Ministry of Education, Chongqing, China

  • School of Urban Construction and Environmental Engineering, Chongqing University, Chongqing, China; Center of Space Exploration, Ministry of Education, Chongqing, China

  • School of Urban Construction and Environmental Engineering, Chongqing University, Chongqing, China

  • School of Urban Construction and Environmental Engineering, Chongqing University, Chongqing, China

  • School of Urban Construction and Environmental Engineering, Chongqing University, Chongqing, China

  • School of Urban Construction and Environmental Engineering, Chongqing University, Chongqing, China; Center of Space Exploration, Ministry of Education, Chongqing, China

  • Department of Pharmacy, The Second Affiliated Hospital, Army Medical University, Chongqing, China

  • Department of Pharmacy, The Second Affiliated Hospital, Army Medical University, Chongqing, China

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