Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking
International Journal of Ophthalmology & Visual Science
Volume 3, Issue 1, March 2018, Pages: 7-11
Received: Feb. 4, 2018;
Accepted: Feb. 24, 2018;
Published: Mar. 24, 2018
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Ahmed Mohamed Reda, Department of Ophthalmology, Faculty of Medicine, Ain Sham University, Cairo, Egypt
Ahmed Shafek Elridy, Department of Ophthalmology, Faculty of Medicine, Ain Sham University, Cairo, Egypt
Reham Fawzy Elshinawy, Department of Ophthalmology, Faculty of Medicine, Ain Sham University, Cairo, Egypt
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This retrospective study was designed to evaluate the efficacy and safety of simultaneous topography-guided PRK plus cross linking for patients with mild to moderate keratoconus and to evaluate the stability of the cone. The patients were evaluated over two years for the progression and stability of the cone by the Allegro Pentacam Oculyzer to assess the changes of corneal curvatures (K readings) and the stability of the cone after the surgery and evaluating uncorrected distance (UDVA) and best corrected (CDVA) visual acuities. The follow-up results showed that UDVA improved from 0.4±0.3 to 0.7±0.1 and CDVA changed from 0.6±0.1 to 0.8±0.1 (P < 0.001). The keratometry value decreased from 44.1±2.2 to 41.4±1.6 D for K1, and from 46.4±2.6 to 43.5±1.7 for K2 (P < 0.001). This combined procedure offers a promising method to stabilize the corneal surface with reducing higher order aberrations so enhancing quality of vision in keratoconus patients.
Keratoconus, Topography, Cross-Linking, PRK
To cite this article
Ahmed Mohamed Reda,
Ahmed Shafek Elridy,
Reham Fawzy Elshinawy,
Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking, International Journal of Ophthalmology & Visual Science.
Vol. 3, No. 1,
2018, pp. 7-11.
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Kennedy RH, Bourne WM, Dyer JA. A 48-year clinical and epidemiologic study of keratoconus. Am J Ophthalmol 1986; 101:267-73.
Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 2003; 135:620-7.
Asri D, Touboul D, Fournié P, Malet F, Garra C, Gallois A, et al. Corneal collagen crosslinking in progressive keratoconus: Multicenter results from the French National Reference Center for Keratoconus. J Cataract Refract Surg 2011; 37:2137-43.
Derakhshan A, Shandiz JH, Ahadi M, Daneshvar R, Esmaily H. Short-term outcomes of collagen crosslinking for early keratoconus. J Ophthalmic Vis Res 2011; 6:155-9.
Wollensak G, Spoerl E, Seiler T. Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross-linking. J Cataract Refract Surg 2003; 29:1780-5.
Kohlhaas M, Spoerl E, Schilde T, Unger G, Wittig C, Pillunat LE. Biomechanical evidence of the distribution of cross-links in corneas treated with riboflavin and ultraviolet a light. J Cataract Refract Surg 2006; 32:279-83.
Spoerl E, Wollensak G, Seiler T. Increased resistance of crosslinked cornea against enzymatic digestion. Curr Eye Res 2004; 29:35-40.
Koller T, Mrochen M, Seiler T. Complication and failure rates after corneal crosslinking. J Cataract Refract Surg 2009; 35:1358-62.
Greenstein SA, Fry KL, Hersh PS. Corneal topography indices after corneal collagen crosslinking for keratoconus and corneal ectasia: One-year results. J Cataract Refract Surg 2011; 37:1282-90.
Sakla H, Altroudi W, Munoz G, Albarran Diego C. Simultaneous topography-guided partial photorefractive keratectomy and corneal collagen crosslinking for keratoconus. J cataract Refract Surg. 2014 Sep; 40 (9): 1430-8.
Vinciguerra P, Albè E, Trazza S, Rosetta P, Vinciguerra R, Seiler T, et al. Refractive, topographic, tomographic, and aberrometric analysis of keratoconic eyes undergoing corneal cross-linking. Ophthalmology 2009; 116:369-78.
Stojanovic A, Zhang J, Chen X, et al. Topography- guided transepithelial surface ablation followed by corneal collagen crosslinking performed in a single procedure for the treatment of keratoconus and pellucid marginal degeneration. J Refract Surg. 2010; 26: 145-52.
Mukherjee AN, Vasilis Selmis, Iaonnis Aslanides. Transepithelial Phototorefractive Keratectomy with Crosslinking for Keratoconus. Open Ophthalmol J. 2013; 7: 63-68.