Background: Herpes Zoster Ophthalmicus (HZO) occurs due to reactivation of latent varicella zoster virus within the gasserian ganglion involving the ophthalmic division of the trigeminal nerve. HZO often has a chronic course with significant ocular morbidity as eye is considered potentially serious of all sites of herpes zoster owing to its delicate nature. Purpose:1. To study the mode of presentation, ocular manifestations and complications of herpes zoster ophthalmicus (HZO) 2. To analyse the predisposing factors for the development of HZO. Materials and Methods: A prospective clinical study was done in 20 patients who were clinically diagnosed with HZO in the outpatient department of ophthalmology over a period of one year. They were subjected to a detailed general and ocular examination and were treated medically with close follow up. Result: Advancing age was the most common risk factor. Acute neuralgia was the commonest presenting symptom (75%). Ocular involvement was seen in 16 patients with no bilaterality. Conjunctiva (60%) was the most common ocular structure involved followed by Cornea (45%). Anterior uveitis (20%) was complicated by haemorrhagic uveitis and orbital apex syndrome with total external ophthalmoplegia. Post herpetic neuralgia was the commonest complication seen. Conclusion: The potential manifestations of HZO are myriad. Development of serious inflammatory complications was associated with delay in therapy. Hence timely diagnosis and management are critical in limiting ocular morbidity
DOI | 10.11648/j.ijovs.20190401.14 |
Published in | International Journal of Ophthalmology & Visual Science (Volume 4, Issue 1, March 2019) |
Page(s) | 19-23 |
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2024. Published by Science Publishing Group |
Herpes Zoster Ophthalmicus (HZO), Acyclovir, Orbital Apex Syndrome, Post Herpetic Neuralgia
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APA Style
Prathibha Shanthaveerappa, Remya Joseph Parappallil. (2019). The Clinical Profile and Ocular Manifestations of Herpes Zoster Ophthalmicus- A Hospital Based Study. International Journal of Ophthalmology & Visual Science, 4(1), 19-23. https://doi.org/10.11648/j.ijovs.20190401.14
ACS Style
Prathibha Shanthaveerappa; Remya Joseph Parappallil. The Clinical Profile and Ocular Manifestations of Herpes Zoster Ophthalmicus- A Hospital Based Study. Int. J. Ophthalmol. Vis. Sci. 2019, 4(1), 19-23. doi: 10.11648/j.ijovs.20190401.14
AMA Style
Prathibha Shanthaveerappa, Remya Joseph Parappallil. The Clinical Profile and Ocular Manifestations of Herpes Zoster Ophthalmicus- A Hospital Based Study. Int J Ophthalmol Vis Sci. 2019;4(1):19-23. doi: 10.11648/j.ijovs.20190401.14
@article{10.11648/j.ijovs.20190401.14, author = {Prathibha Shanthaveerappa and Remya Joseph Parappallil}, title = {The Clinical Profile and Ocular Manifestations of Herpes Zoster Ophthalmicus- A Hospital Based Study}, journal = {International Journal of Ophthalmology & Visual Science}, volume = {4}, number = {1}, pages = {19-23}, doi = {10.11648/j.ijovs.20190401.14}, url = {https://doi.org/10.11648/j.ijovs.20190401.14}, eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijovs.20190401.14}, abstract = {Background: Herpes Zoster Ophthalmicus (HZO) occurs due to reactivation of latent varicella zoster virus within the gasserian ganglion involving the ophthalmic division of the trigeminal nerve. HZO often has a chronic course with significant ocular morbidity as eye is considered potentially serious of all sites of herpes zoster owing to its delicate nature. Purpose:1. To study the mode of presentation, ocular manifestations and complications of herpes zoster ophthalmicus (HZO) 2. To analyse the predisposing factors for the development of HZO. Materials and Methods: A prospective clinical study was done in 20 patients who were clinically diagnosed with HZO in the outpatient department of ophthalmology over a period of one year. They were subjected to a detailed general and ocular examination and were treated medically with close follow up. Result: Advancing age was the most common risk factor. Acute neuralgia was the commonest presenting symptom (75%). Ocular involvement was seen in 16 patients with no bilaterality. Conjunctiva (60%) was the most common ocular structure involved followed by Cornea (45%). Anterior uveitis (20%) was complicated by haemorrhagic uveitis and orbital apex syndrome with total external ophthalmoplegia. Post herpetic neuralgia was the commonest complication seen. Conclusion: The potential manifestations of HZO are myriad. Development of serious inflammatory complications was associated with delay in therapy. Hence timely diagnosis and management are critical in limiting ocular morbidity}, year = {2019} }
TY - JOUR T1 - The Clinical Profile and Ocular Manifestations of Herpes Zoster Ophthalmicus- A Hospital Based Study AU - Prathibha Shanthaveerappa AU - Remya Joseph Parappallil Y1 - 2019/04/18 PY - 2019 N1 - https://doi.org/10.11648/j.ijovs.20190401.14 DO - 10.11648/j.ijovs.20190401.14 T2 - International Journal of Ophthalmology & Visual Science JF - International Journal of Ophthalmology & Visual Science JO - International Journal of Ophthalmology & Visual Science SP - 19 EP - 23 PB - Science Publishing Group SN - 2637-3858 UR - https://doi.org/10.11648/j.ijovs.20190401.14 AB - Background: Herpes Zoster Ophthalmicus (HZO) occurs due to reactivation of latent varicella zoster virus within the gasserian ganglion involving the ophthalmic division of the trigeminal nerve. HZO often has a chronic course with significant ocular morbidity as eye is considered potentially serious of all sites of herpes zoster owing to its delicate nature. Purpose:1. To study the mode of presentation, ocular manifestations and complications of herpes zoster ophthalmicus (HZO) 2. To analyse the predisposing factors for the development of HZO. Materials and Methods: A prospective clinical study was done in 20 patients who were clinically diagnosed with HZO in the outpatient department of ophthalmology over a period of one year. They were subjected to a detailed general and ocular examination and were treated medically with close follow up. Result: Advancing age was the most common risk factor. Acute neuralgia was the commonest presenting symptom (75%). Ocular involvement was seen in 16 patients with no bilaterality. Conjunctiva (60%) was the most common ocular structure involved followed by Cornea (45%). Anterior uveitis (20%) was complicated by haemorrhagic uveitis and orbital apex syndrome with total external ophthalmoplegia. Post herpetic neuralgia was the commonest complication seen. Conclusion: The potential manifestations of HZO are myriad. Development of serious inflammatory complications was associated with delay in therapy. Hence timely diagnosis and management are critical in limiting ocular morbidity VL - 4 IS - 1 ER -