Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review
International Journal of Ophthalmology & Visual Science
Volume 4, Issue 4, December 2019, Pages: 66-70
Received: Aug. 1, 2019; Accepted: Sep. 25, 2019; Published: Oct. 10, 2019
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Authors
Manuel Augusto Pereira Vilela, Medical School, Federal University of Health Sciences, Porto Alegre, Brazil; Ivo Corrêa-Meyer Institute, Porto Alegre, Brazil
Carina Graziottin Colossi, Ivo Corrêa-Meyer Institute, Porto Alegre, Brazil
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Abstract
Background: Optic disc is a region with a complex vascular stratification, with components from the posterior ciliary arteries and central retinal artery. Nonarteritic anterior ischemic optic neuropathy (NA-AION) and papilledema can produce disc edema and visual fields defects. Optical coherence tomography angiography (OCTA) can aid in the rapid differentiation of cases when signals overlap. Objective: The purpose of this systematic review is to discuss the current information concerning the signs in OCTA that eventually could help to differentiate these situations and analyze the best diagnostic evidence. Methods: A systematic search was conducted in the MEDLINE ("Medical Literature Analysis and Retrieval System Online") via Pubmed; Embase, Scopus, Web of Science, Google Scholar, BVS databases, in addition to a manual search on studies published, from inception until July 2019, with no language restriction. Results: Of the 20935 articles identified, eleven were included. Different methodologies, sample characteristics, types of equipment, potential artifacts, segmentation errors were the main arguments against formal meta-analysis. Conclusion: The main differentiation of papilledema from NA-AION is the vascular dropout. Density values in both retina and optic nerve head images were significantly lower in NA-AION. These vascular changes appears to precede detectable structural or visual field damage.
Keywords
Ischemic Optic Neuropathy, Optical Coherence Tomography Angiography, Papilledema
To cite this article
Manuel Augusto Pereira Vilela, Carina Graziottin Colossi, Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review, International Journal of Ophthalmology & Visual Science. Vol. 4, No. 4, 2019, pp. 66-70. doi: 10.11648/j.ijovs.20190404.12
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
https://www.ncbi.nlm.nih.gov/pubmed/advanced. Accessed 15/july/2019
[2]
Biousse V, Newman NJ. Ischemic Optic Neuropathies. N Engl J Med (2015); 372 (25): 2428-36.
[3]
Hayreh SS. Ischemic optic neuropathy. Prog Retin Eye Res. (2009); 28 (1): 34-62.
[4]
Hayreh SS. Pathogenesis of oedema of the optic disc disc (papilloedema). A preliminary report. Br J Ophthalmol (1964); 48: 522-543.
[5]
Egger M, Davey-Smith G, Altman D. Systematic reviews in health care: mata-analysis in context. Philadelphia, John Wiley and Sons, 2008.
[6]
PRISMA. Preferred reporting items for systematic reviews and meta-analyses. Available from: http://www.prisma-statement.org/index.htm, cited 2019, July 15.
[7]
Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis for observational studies in epidemiology: a proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group. JAMA (2000); 283: (12).
[8]
PROSPERO. International prospective register of systematic reviews. Available from: http://www.crd.york.ac.uk/PROSPERO/ [cited 2019 July 15].
[9]
Wells GA, Shea B, O'Connel D. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analysis. Ottawa: The Ottawa Hospital, 2000.
[10]
Ghasemi Falavarjani K, Tian JJ, Garcia GA, et al. Swept-source optical coherence tomography angiography of the optic disk in optic in optic neuropathy. Retina (2016); 36 Suppl 1: S168-S177. doi: 10.1097/IAE.0000000000001259.
[11]
Balducci N, Morara M, Veronese C, et al. Optical coherence tomography angiography in acute arteritic and non-arteritic anterior ischemic optic neuropathy. Graefes Arch Clin Exp Ophthalmol (2017); 255 (11): 2255-2261.
[12]
Hata M, Oishi A, Muraoka Y, et al. Structural and Functional Analyses in Nonarteritic Anterior Ischemic Optic Neuropathy: Optical Coherence Tomography Angiography Study. J Neuroophthalmol (2017); 37 (2): 140-148.
[13]
Wright Mayes E, Cole ED, Dang S, et al. Optical Coherence Tomography Angiography in Nonarteritic Anterior Ischemic Optic Neuropathy. J Neuroophthalmol (2017); 37 (4): 358–364.
[14]
Gaier ED, Gilbert Al, Rizzo JF, et al. Quantitative analysis of optical coherence tomographic angiography (OCT-A) in patients with non-arteritic anterior ischemic optic neropathy (NAION) corresponds to visual function. PLoS ONE (2018); 13 (6): e0199793.
[15]
Rebolleda G, Diez-Álvarez L, Garcia Marin Y, et al. Reduction of peripapillary vessel density by optical coherence tomography angiography from acute to the atrophic stage in non-arteritic anterior ischaemic optic neuropathy. Ophthalmologica (2018); 240 (4); 191-199.
[16]
Augstburger E, Zéboulon P, Keilani C, et al. Retinal and Choroidal Microvasculature in Nonarteritic Anterior Ischemic Optic Neuropathy: An Optical Coherence Tomography Angiography Study. Invest Ophthalmol Vis Sci. (2018); 59: 870–877.
[17]
Song Y, Min JY, Mao L, Gong YY. Microvasculature dropout detected by the optical coherence tomography angiography in nonarteritic anterior ischemic optic neuropathy. Lasers Surg. Med (2018); 50 (3): 194–201.
[18]
Ling J-W, Yin X, Lu, Q-Y, et al. Optical coherence tomography angiography of optic disc in non-arteritic anterior ischemic optic neuropathy. Int j Ophthalmol (2017); 10 (9): 1402-1406.
[19]
Fard MA, Sahraiyan A, Jalili J, et al. Optical coherence tomography angiography in papilledema compared with pseudopapilledema. Invest Ophthalmol Vis Sci (2019); 60: 168-175.
[20]
Rougier MB, Goff L, Korobelnik JF. Optical coherence tomography angiography at the acute phase of optic disc edema. Eye Vis (2018); 5: 15. doi: 10.1186/s40662-018-0109-y.
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