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Unilateral Frosted Branch Angiitis Treated with Intravitreal Dexamethasone Implant

Received: 17 July 2020    Accepted: 24 August 2020    Published: 24 September 2020
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Abstract

Frosted branch angiitis (FBA), a relatively rare condition, is a retinal perivasculitis with severe retinal vessel sheathing resembling the frosted branches of a tree. It can be a Primary Idiopathic FBA or Secondary FBA when associated with systemic conditions like viral infections, sarcoid etc. Primary frosted branch angiitis causes characteristic florid, translucent retinal perivascular sheathing of both arterioles and venules in association with variable uveitis, retinal edema and visual loss. Additional retinal findings may include intraretinal haemorrhages, hard exudates, and serous exudative detachments of the macula and periphery. It is unclear whether retinal frosted branch angiitis is a distinct clinical syndrome or a clinical sign increasingly recognised in a number of inflammatory conditions. Hence, retinal frosted branch angiitis may be more of a sign than a separate disease. Treatment is usually with corticosteroids and normally leads to a good visual recovery. We report a case of primary unilateral frosted branch angiitis with large areas of capillary drop out and severe macular edema. It was successfully managed with intravitreal injection of Dexamethasone Implant (Ozurdex TM) in conjunction with a very short course of systemic steroids. To our knowledge, this is the first documented case of primary unilateral FBA treated with systemic steroids and an intravitreal dexamethasone implant.

Published in International Journal of Ophthalmology & Visual Science (Volume 5, Issue 3)
DOI 10.11648/j.ijovs.20200503.12
Page(s) 75-79
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Frosted Branch Angiitis, Unilateral, Dexamethasone Implant

References
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Cite This Article
  • APA Style

    Nishikant Borse, Veena Borse. (2020). Unilateral Frosted Branch Angiitis Treated with Intravitreal Dexamethasone Implant. International Journal of Ophthalmology & Visual Science, 5(3), 75-79. https://doi.org/10.11648/j.ijovs.20200503.12

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    ACS Style

    Nishikant Borse; Veena Borse. Unilateral Frosted Branch Angiitis Treated with Intravitreal Dexamethasone Implant. Int. J. Ophthalmol. Vis. Sci. 2020, 5(3), 75-79. doi: 10.11648/j.ijovs.20200503.12

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    AMA Style

    Nishikant Borse, Veena Borse. Unilateral Frosted Branch Angiitis Treated with Intravitreal Dexamethasone Implant. Int J Ophthalmol Vis Sci. 2020;5(3):75-79. doi: 10.11648/j.ijovs.20200503.12

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  • @article{10.11648/j.ijovs.20200503.12,
      author = {Nishikant Borse and Veena Borse},
      title = {Unilateral Frosted Branch Angiitis Treated with Intravitreal Dexamethasone Implant},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {5},
      number = {3},
      pages = {75-79},
      doi = {10.11648/j.ijovs.20200503.12},
      url = {https://doi.org/10.11648/j.ijovs.20200503.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20200503.12},
      abstract = {Frosted branch angiitis (FBA), a relatively rare condition, is a retinal perivasculitis with severe retinal vessel sheathing resembling the frosted branches of a tree. It can be a Primary Idiopathic FBA or Secondary FBA when associated with systemic conditions like viral infections, sarcoid etc. Primary frosted branch angiitis causes characteristic florid, translucent retinal perivascular sheathing of both arterioles and venules in association with variable uveitis, retinal edema and visual loss. Additional retinal findings may include intraretinal haemorrhages, hard exudates, and serous exudative detachments of the macula and periphery. It is unclear whether retinal frosted branch angiitis is a distinct clinical syndrome or a clinical sign increasingly recognised in a number of inflammatory conditions. Hence, retinal frosted branch angiitis may be more of a sign than a separate disease. Treatment is usually with corticosteroids and normally leads to a good visual recovery.  We report a case of primary unilateral frosted branch angiitis with large areas of capillary drop out and severe macular edema. It was successfully managed with intravitreal injection of Dexamethasone Implant (Ozurdex TM) in conjunction with a very short course of systemic steroids. To our knowledge, this is the first documented case of primary unilateral FBA treated with systemic steroids and an intravitreal dexamethasone implant.},
     year = {2020}
    }
    

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    T1  - Unilateral Frosted Branch Angiitis Treated with Intravitreal Dexamethasone Implant
    AU  - Nishikant Borse
    AU  - Veena Borse
    Y1  - 2020/09/24
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    N1  - https://doi.org/10.11648/j.ijovs.20200503.12
    DO  - 10.11648/j.ijovs.20200503.12
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    JF  - International Journal of Ophthalmology & Visual Science
    JO  - International Journal of Ophthalmology & Visual Science
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    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.ijovs.20200503.12
    AB  - Frosted branch angiitis (FBA), a relatively rare condition, is a retinal perivasculitis with severe retinal vessel sheathing resembling the frosted branches of a tree. It can be a Primary Idiopathic FBA or Secondary FBA when associated with systemic conditions like viral infections, sarcoid etc. Primary frosted branch angiitis causes characteristic florid, translucent retinal perivascular sheathing of both arterioles and venules in association with variable uveitis, retinal edema and visual loss. Additional retinal findings may include intraretinal haemorrhages, hard exudates, and serous exudative detachments of the macula and periphery. It is unclear whether retinal frosted branch angiitis is a distinct clinical syndrome or a clinical sign increasingly recognised in a number of inflammatory conditions. Hence, retinal frosted branch angiitis may be more of a sign than a separate disease. Treatment is usually with corticosteroids and normally leads to a good visual recovery.  We report a case of primary unilateral frosted branch angiitis with large areas of capillary drop out and severe macular edema. It was successfully managed with intravitreal injection of Dexamethasone Implant (Ozurdex TM) in conjunction with a very short course of systemic steroids. To our knowledge, this is the first documented case of primary unilateral FBA treated with systemic steroids and an intravitreal dexamethasone implant.
    VL  - 5
    IS  - 3
    ER  - 

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Author Information
  • Insight Eye Clinic, Mumbai, India

  • Insight Eye Clinic, Mumbai, India

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