International Journal of Ophthalmology & Visual Science

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Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review

Received: 01 August 2019    Accepted: 25 September 2019    Published: 10 October 2019
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Abstract

Background: Optic disc is a region with a complex vascular stratification, with components from the posterior ciliary arteries and central retinal artery. Nonarteritic anterior ischemic optic neuropathy (NA-AION) and papilledema can produce disc edema and visual fields defects. Optical coherence tomography angiography (OCTA) can aid in the rapid differentiation of cases when signals overlap. Objective: The purpose of this systematic review is to discuss the current information concerning the signs in OCTA that eventually could help to differentiate these situations and analyze the best diagnostic evidence. Methods: A systematic search was conducted in the MEDLINE ("Medical Literature Analysis and Retrieval System Online") via Pubmed; Embase, Scopus, Web of Science, Google Scholar, BVS databases, in addition to a manual search on studies published, from inception until July 2019, with no language restriction. Results: Of the 20935 articles identified, eleven were included. Different methodologies, sample characteristics, types of equipment, potential artifacts, segmentation errors were the main arguments against formal meta-analysis. Conclusion: The main differentiation of papilledema from NA-AION is the vascular dropout. Density values in both retina and optic nerve head images were significantly lower in NA-AION. These vascular changes appears to precede detectable structural or visual field damage.

DOI 10.11648/j.ijovs.20190404.12
Published in International Journal of Ophthalmology & Visual Science (Volume 4, Issue 4, December 2019)
Page(s) 66-70
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ischemic Optic Neuropathy, Optical Coherence Tomography Angiography, Papilledema

References
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[11] Balducci N, Morara M, Veronese C, et al. Optical coherence tomography angiography in acute arteritic and non-arteritic anterior ischemic optic neuropathy. Graefes Arch Clin Exp Ophthalmol (2017); 255 (11): 2255-2261.
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[14] Gaier ED, Gilbert Al, Rizzo JF, et al. Quantitative analysis of optical coherence tomographic angiography (OCT-A) in patients with non-arteritic anterior ischemic optic neropathy (NAION) corresponds to visual function. PLoS ONE (2018); 13 (6): e0199793.
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[16] Augstburger E, Zéboulon P, Keilani C, et al. Retinal and Choroidal Microvasculature in Nonarteritic Anterior Ischemic Optic Neuropathy: An Optical Coherence Tomography Angiography Study. Invest Ophthalmol Vis Sci. (2018); 59: 870–877.
[17] Song Y, Min JY, Mao L, Gong YY. Microvasculature dropout detected by the optical coherence tomography angiography in nonarteritic anterior ischemic optic neuropathy. Lasers Surg. Med (2018); 50 (3): 194–201.
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Author Information
  • Medical School, Federal University of Health Sciences, Porto Alegre, Brazil; Ivo Corrêa-Meyer Institute, Porto Alegre, Brazil

  • Ivo Corrêa-Meyer Institute, Porto Alegre, Brazil

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    Manuel Augusto Pereira Vilela, Carina Graziottin Colossi. (2019). Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review. International Journal of Ophthalmology & Visual Science, 4(4), 66-70. https://doi.org/10.11648/j.ijovs.20190404.12

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    Manuel Augusto Pereira Vilela; Carina Graziottin Colossi. Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review. Int. J. Ophthalmol. Vis. Sci. 2019, 4(4), 66-70. doi: 10.11648/j.ijovs.20190404.12

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    AMA Style

    Manuel Augusto Pereira Vilela, Carina Graziottin Colossi. Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review. Int J Ophthalmol Vis Sci. 2019;4(4):66-70. doi: 10.11648/j.ijovs.20190404.12

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  • @article{10.11648/j.ijovs.20190404.12,
      author = {Manuel Augusto Pereira Vilela and Carina Graziottin Colossi},
      title = {Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {4},
      number = {4},
      pages = {66-70},
      doi = {10.11648/j.ijovs.20190404.12},
      url = {https://doi.org/10.11648/j.ijovs.20190404.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijovs.20190404.12},
      abstract = {Background: Optic disc is a region with a complex vascular stratification, with components from the posterior ciliary arteries and central retinal artery. Nonarteritic anterior ischemic optic neuropathy (NA-AION) and papilledema can produce disc edema and visual fields defects. Optical coherence tomography angiography (OCTA) can aid in the rapid differentiation of cases when signals overlap. Objective: The purpose of this systematic review is to discuss the current information concerning the signs in OCTA that eventually could help to differentiate these situations and analyze the best diagnostic evidence. Methods: A systematic search was conducted in the MEDLINE ("Medical Literature Analysis and Retrieval System Online") via Pubmed; Embase, Scopus, Web of Science, Google Scholar, BVS databases, in addition to a manual search on studies published, from inception until July 2019, with no language restriction. Results: Of the 20935 articles identified, eleven were included. Different methodologies, sample characteristics, types of equipment, potential artifacts, segmentation errors were the main arguments against formal meta-analysis. Conclusion: The main differentiation of papilledema from NA-AION is the vascular dropout. Density values in both retina and optic nerve head images were significantly lower in NA-AION. These vascular changes appears to precede detectable structural or visual field damage.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Optical Coherence Tomography Angiography to Detect and Differentiate Ischemic Optic Neuropathy from Papilledema - Systematic Review
    AU  - Manuel Augusto Pereira Vilela
    AU  - Carina Graziottin Colossi
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    DO  - 10.11648/j.ijovs.20190404.12
    T2  - International Journal of Ophthalmology & Visual Science
    JF  - International Journal of Ophthalmology & Visual Science
    JO  - International Journal of Ophthalmology & Visual Science
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    EP  - 70
    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.ijovs.20190404.12
    AB  - Background: Optic disc is a region with a complex vascular stratification, with components from the posterior ciliary arteries and central retinal artery. Nonarteritic anterior ischemic optic neuropathy (NA-AION) and papilledema can produce disc edema and visual fields defects. Optical coherence tomography angiography (OCTA) can aid in the rapid differentiation of cases when signals overlap. Objective: The purpose of this systematic review is to discuss the current information concerning the signs in OCTA that eventually could help to differentiate these situations and analyze the best diagnostic evidence. Methods: A systematic search was conducted in the MEDLINE ("Medical Literature Analysis and Retrieval System Online") via Pubmed; Embase, Scopus, Web of Science, Google Scholar, BVS databases, in addition to a manual search on studies published, from inception until July 2019, with no language restriction. Results: Of the 20935 articles identified, eleven were included. Different methodologies, sample characteristics, types of equipment, potential artifacts, segmentation errors were the main arguments against formal meta-analysis. Conclusion: The main differentiation of papilledema from NA-AION is the vascular dropout. Density values in both retina and optic nerve head images were significantly lower in NA-AION. These vascular changes appears to precede detectable structural or visual field damage.
    VL  - 4
    IS  - 4
    ER  - 

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