International Journal of Ophthalmology & Visual Science

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Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study

Received: 07 October 2019    Accepted: 26 October 2019    Published: 05 November 2019
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Abstract

Congenital and genetic ocular disorders are linked to parental consanguinity. The aims was to investigate the effects of consanguineous marriages on the refractive errors of preschool-aged and adolescent patients. Two sample groups were recruited: the preschooler group (3–6 years; 335 participants) and the adolescent group (12–20 years; 998 participants). The required sample size was calculated using a sample size estimation software. Visual acuity was measured using the 15-line Lea symbols chart in the pre-school aged group and non-illuminated ETDRS VA chart in the adolescent group. Spherical equivalent refractive errors were noted with near-retinoscopy technique in young children and with the ARK-30 autorefractor in the adolescent group. In order to explore the impact of consanguineous marriages, the data were analyzed separately based on the age group using SPSS version 21 software. In the preschooler group, myopia was found in 4.2%, hyperopia in 8.1%, and astigmatism in 20%. Three children had high myopic scores (-10.00 D, -13.50 D and -17.50 D). In the adolescent group, 45.6% participants were myopic, 3.8% were hyperopic, and 22.3% were astigmatic. Despite the higher frequency of RE in those 15 years and older in the cousins group and the consanguineous parents of the three preschool-aged children with high myopia, there were no statistically significant (p>0.05) evidence that consanguineous marriages impact the refractive errors of their children. In conclusion, despite previous studies showing a link between ocular genetic or congenital disorders and consanguinity, no such link could be established with regard to refractive errors.

DOI 10.11648/j.ijovs.20190404.15
Published in International Journal of Ophthalmology & Visual Science (Volume 4, Issue 4, December 2019)
Page(s) 81-87
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Consanguinity, Consanguineous Marriages, Refractive Errors, Myopia, Saudi, Arabs

References
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Author Information
  • Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia

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  • APA Style

    Ali Mazyed Alsaqr. (2019). Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study. International Journal of Ophthalmology & Visual Science, 4(4), 81-87. https://doi.org/10.11648/j.ijovs.20190404.15

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    Ali Mazyed Alsaqr. Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study. Int. J. Ophthalmol. Vis. Sci. 2019, 4(4), 81-87. doi: 10.11648/j.ijovs.20190404.15

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    AMA Style

    Ali Mazyed Alsaqr. Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A Cross-sectional Study. Int J Ophthalmol Vis Sci. 2019;4(4):81-87. doi: 10.11648/j.ijovs.20190404.15

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  • @article{10.11648/j.ijovs.20190404.15,
      author = {Ali Mazyed Alsaqr},
      title = {Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A  Cross-sectional Study},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {4},
      number = {4},
      pages = {81-87},
      doi = {10.11648/j.ijovs.20190404.15},
      url = {https://doi.org/10.11648/j.ijovs.20190404.15},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijovs.20190404.15},
      abstract = {Congenital and genetic ocular disorders are linked to parental consanguinity. The aims was to investigate the effects of consanguineous marriages on the refractive errors of preschool-aged and adolescent patients. Two sample groups were recruited: the preschooler group (3–6 years; 335 participants) and the adolescent group (12–20 years; 998 participants). The required sample size was calculated using a sample size estimation software. Visual acuity was measured using the 15-line Lea symbols chart in the pre-school aged group and non-illuminated ETDRS VA chart in the adolescent group. Spherical equivalent refractive errors were noted with near-retinoscopy technique in young children and with the ARK-30 autorefractor in the adolescent group. In order to explore the impact of consanguineous marriages, the data were analyzed separately based on the age group using SPSS version 21 software. In the preschooler group, myopia was found in 4.2%, hyperopia in 8.1%, and astigmatism in 20%. Three children had high myopic scores (-10.00 D, -13.50 D and -17.50 D). In the adolescent group, 45.6% participants were myopic, 3.8% were hyperopic, and 22.3% were astigmatic. Despite the higher frequency of RE in those 15 years and older in the cousins group and the consanguineous parents of the three preschool-aged children with high myopia, there were no statistically significant (p>0.05) evidence that consanguineous marriages impact the refractive errors of their children. In conclusion, despite previous studies showing a link between ocular genetic or congenital disorders and consanguinity, no such link could be established with regard to refractive errors.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Relationship Between Consanguineous Marriages and Incidence and Severity of Refractive Errors: A  Cross-sectional Study
    AU  - Ali Mazyed Alsaqr
    Y1  - 2019/11/05
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ijovs.20190404.15
    DO  - 10.11648/j.ijovs.20190404.15
    T2  - International Journal of Ophthalmology & Visual Science
    JF  - International Journal of Ophthalmology & Visual Science
    JO  - International Journal of Ophthalmology & Visual Science
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    EP  - 87
    PB  - Science Publishing Group
    SN  - 2637-3858
    UR  - https://doi.org/10.11648/j.ijovs.20190404.15
    AB  - Congenital and genetic ocular disorders are linked to parental consanguinity. The aims was to investigate the effects of consanguineous marriages on the refractive errors of preschool-aged and adolescent patients. Two sample groups were recruited: the preschooler group (3–6 years; 335 participants) and the adolescent group (12–20 years; 998 participants). The required sample size was calculated using a sample size estimation software. Visual acuity was measured using the 15-line Lea symbols chart in the pre-school aged group and non-illuminated ETDRS VA chart in the adolescent group. Spherical equivalent refractive errors were noted with near-retinoscopy technique in young children and with the ARK-30 autorefractor in the adolescent group. In order to explore the impact of consanguineous marriages, the data were analyzed separately based on the age group using SPSS version 21 software. In the preschooler group, myopia was found in 4.2%, hyperopia in 8.1%, and astigmatism in 20%. Three children had high myopic scores (-10.00 D, -13.50 D and -17.50 D). In the adolescent group, 45.6% participants were myopic, 3.8% were hyperopic, and 22.3% were astigmatic. Despite the higher frequency of RE in those 15 years and older in the cousins group and the consanguineous parents of the three preschool-aged children with high myopia, there were no statistically significant (p>0.05) evidence that consanguineous marriages impact the refractive errors of their children. In conclusion, despite previous studies showing a link between ocular genetic or congenital disorders and consanguinity, no such link could be established with regard to refractive errors.
    VL  - 4
    IS  - 4
    ER  - 

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