Evaluation of Some Haematological Parameters Among Post-menopausal Women in Bayelsa State, Nigeria: A Case Study of Patients Attending Federal Medical Centre, Yenagoa
American Journal of Laboratory Medicine
Volume 2, Issue 6, November 2017, Pages: 132-136
Received: Sep. 10, 2017; Accepted: Sep. 23, 2017; Published: Nov. 2, 2017
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Authors
Benjamin Onyema Eledo, Department of Medical Laboratory Science, Faculty of Health Sciences, Madonna University, Elele, Nigeria; Haematology and Blood Transfusion Department Federal Medical Centre, Yenagoa, Nigeria
Dennis Oju Allagoa, Department of Gynecology and Obstetrics, Federal Medical Centre, Yenagoa, Nigeria
Anthony Ugochukwu Ihedioha, Department of Medical Services, Federal University Otuoke, Otuoke, Nigeria
Kingsley Excel Dunga, Department of Medical Laboratory Science, Faculty of Health Sciences, Madonna University, Elele, Nigeria
Sylvester Chibueze Izah, Department of Biological Sciences, Faculty of Science, Niger Delta University, Wilberforce Island, Nigeria
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Abstract
This study evaluated some haematological parameters among post-menopausal women in Yenagoa, Bayelsa state, Nigeria. Sixty two post-menopausal women within the age of 52 –70 and forty adult females within the age of 18 – 32 participated in this study. About 5ml of blood was collected from each participant and analyzed using Westergren method for erythrocyte sedimentation rate (ESR) and automated haematology analyser (System XS-1000i) for packed cell volume (PCV), haemoglobin (Hb), total white cell count (WBC), platelet count (PLT) and differential viz: lymphocytes, neutrophil, monocytes, eosinophils and basophils. Results showed that the test (post-menopausal women) and control subject had 12.21±1.00 g/dl and 13.22±0.71 g/dl respectively (Hb), 36.60±3.00% and 39.70±2.22% respectively (PCV), 5.24±0.63×109/L and 7.23±1.04×109/L respectively (WBC), 174.63±27.46×109/L and 260.20±45.54×109/L respectively (PLT) and 43.02±6.77 mm/hour and 8.08±2.68 mm/hour respectively (ESR). Statistically, there was a significant (P<0.05) reduction in PLT, PCV, Hb and monocytes, and significant increase in ESR and neutrophil among the post-menopausal women when compared to the control. Other blood differential such as lymphocytes, eosinophils and basophils were not affected by menopause. This suggests that post-menopausal changes alter some haematological parameters, which may predispose the women to infections.
Keywords
Age, Estrogen, Haematological Indices, Post-Menopausal, Yenagoa Metropolis
To cite this article
Benjamin Onyema Eledo, Dennis Oju Allagoa, Anthony Ugochukwu Ihedioha, Kingsley Excel Dunga, Sylvester Chibueze Izah, Evaluation of Some Haematological Parameters Among Post-menopausal Women in Bayelsa State, Nigeria: A Case Study of Patients Attending Federal Medical Centre, Yenagoa, American Journal of Laboratory Medicine. Vol. 2, No. 6, 2017, pp. 132-136. doi: 10.11648/j.ajlm.20170206.14
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Eledo, B. O., Buseri, F. I. and Akhogba, A. O. (2015). Evaluation of Some Haematological Parameters Among Pregnant Ijaw Women: An Indigenous West African Tribe. Journal of Health, Medicine and Nursing, 13:10–17.
[2]
Papadopol, V., Damian, O., Palamaru, I., Adam, C., Florescu, N. and Dămăceanu, D. (2001). Maternal haematological and biochemical parameters and pregnancy outcome. The Journal of Preventive Medicine, 9(3): 27-33.
[3]
Achie, L. N., Olorunshola, K. V. and Mabrouk, M. (2011). A Study of Some Red Cell Indices in Menopausal Women in Zaria, Nigeria. Asian Journal of Medical Sciences 3(8): 154-157.
[4]
Akahoshi, M., Soda, M., Nakashima, E., Tominaga, T., Ichimaru, S., Seto, S. and Yano, K. (2002). The effects of body mass index on age at menopause. International Journal of Obesity, 26: 961–968.
[5]
American Association for Clinical Chemistry (AACC) (2017). Menopause. https://labtestsonline.org/understanding/conditions/menopause. Accessed 14th August 2017.
[6]
Moustafa, M. F., Ali, R. R., El saied, S. F. and Taha, S. A. M. (2015). Impact of menopausal symptoms on quality of life among women's in Qena City. IOSR Journal of Nursing and Health Science, 4(2): 49-59.
[7]
Nansseu, J. R. N., Moor, V. J. A., Nouaga, M. E. D., Zing-Awona, B., Tchanana, G. and Ketcha, A. (2016). Atherogenic index of plasma and risk of cardiovascular disease among Cameroonian postmenopausal women. Lipids in Health and Disease, 15:49.
[8]
Elder, J. A. and Thacker, H. L. (2016). Menopause. http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/womens-health/menopause/. Accessed 14th August 2017.
[9]
WebMD (2016). Your Health in Postmenopause. http://www.webmd.com/menopause/guide/health-after-menopause, Accessed 14th August 2017.
[10]
Lages, C. S., Suffia, I., Velilla, P. A., Bin, H., Warshaw, G., Hildeman, D. A., Belkaid, Y. and Chougnet, C. (2008). Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation. J Immunol., 181:1835–1848.
[11]
Gavazzi, G. and Krause, K. H. (2002). The Lancet Infectious Diseases -Ageing and infection. Lancet 2:659–666.
[12]
Pistilli, E. E., Siu, P. M. and Always, S. E. (2007). Interleukin-15 responses to aging and unloading-induced skeletal muscle atrophy. Am J Physiol Cell Physiol., 292: C1298–C1304.
[13]
Sivro, A., Lajoie, J., Kimani, J., Jaoko, W., Plummer, F. A., Fowke, K. and Ball, T. B. (2013). Age and menopause affect the expression of specific cytokines/chemokines in plasma and cervical lavage samples from female sex workers in Nairobi, Kenya. Immunity and Ageing, 10:42.
[14]
Dosi, R., Bhatt, N., Shah, P. and Patell, R. (2014). Cardiovascular disease and menopause. J Clin Diagn Res., 8(2):62–64.
[15]
Allali, F., Aichaoui, S. E., Saoud, B., Maaroufi, H., Abouqal, R. and Hajjaj-Hassouni, N. (2006). The impact of clothing style on bone mineral density among post menopausal women in Morocco: a case-control study. BMC Public Health, 6:135 doi:10.1186/1471-2458-6-135.
[16]
Bączyk, G., Chuchracki, M. and Opala, T. (2013). Effect of selected socio-demographic, clinical and biochemical factors on self-reported quality of life among post-menopausal women with osteoporosis. Ann Agric Environ Med., 20(4): 843–848.
[17]
Eledo, B. O., Dioka, C. E., Amilo, G. I., Ifeanyichukwu, M. O. and Onuoha, E. C. (2015). Evaluation of Some Haematological Parameters Among Marijuana Smokers In Yenagoa, Nigeria. Journal of Biology, Agriculture and Healthcare, 5(12): 103–111.
[18]
Igbeneghu, C. and Odaibo, A. B. (2013). Impact of Acute Malaria on Some Haematological Parameters in A Semi-Urban Community in Southwestern Nigeria. Acta Parasitologica Globalis, 4(1): 01-05.
[19]
Eledo, B. O., Nwoga, M. I., Okamgba, O. C. and Izah, S. C. (2017). Assessment of Some Haemostatic Parameters Among Diabetes Mellitus in Bayelsa state: A case of Patients attending Federal Medical Centre, Yenagoa, Nigeria. European Journal of Clinical and Biomedical Sciences. In press.
[20]
Eledo B. O. (2014). Evaluation of some haematological and immunological parameters in Marijuana smokers in Yenagoa, Bomadi and Okogbe, South-South, Nigeria. PhD dissertation submitted to Department of Medical Laboratory Sciences and Technology, Nnamdi Azikiwe University, Nigeria.159pp.
[21]
Alexy, T., Pais, E. and Meiselman, H. J. (2009). A rapid method to estimate Westergren sedimentation rates. Review of Scientific Instrument, 80(9): 096102. doi: 10.1063/1.3212564.
[22]
Padalia, M. S., Trivedi, R. S., Panchal, P. and Jani, H. (2014). Effect of aging on various haematological parameters. International Journal of Biomedical and Advance Research, 05 (10): 494–495.
[23]
Kim, H. M., Park, J., Ryu, S. Y. and Kim, J. (2007). The Effect of Menopause on the Metabolic Syndrome Among Korean Women. Diabetes Care, 30(3): 701–706.
[24]
Al-Chalaby, S. S. H., Taib, S. M. and Ahmed, A. F. (2006). The Effect of Oral Contraceptive Pills on Haematological Indices Running Title: Haematological Parameters in Oral Contraceptive Users. Tikrit Medical Journal, 12(1):65-69.
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