Effects of Fast Foods in Relation to Free Radicals and Antioxidants
American Journal of Laboratory Medicine
Volume 2, Issue 6, November 2017, Pages: 156-162
Received: May 22, 2017; Accepted: Jun. 15, 2017; Published: Nov. 10, 2017
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Yomna Ali Moustafa Elkhateeb, Microbial Chemistry Department, Genetic Engineering &Biotechnology Division, National Research Centre, Giza, Egypt; Clinical Nutrition Department, College of Applied Medical Sciences, University of Hail, Hail, Kingdom of Saudi Arabia
Mona Rahil Alshammary, Clinical Nutrition Department, College of Applied Medical Sciences, University of Hail, Hail, Kingdom of Saudi Arabia
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Fast foods is a part of the new life. One third of adults the United Saudi Kingdom (U.S) eat fast foods. About 7% of American report eating fast food every day, certain groups are more likely to be more frequent users. Youth are the biggest consumers; adolescents and young adults get 20% and 31.5% of their total daily calories from fast food, respectively. When fast foods frequently replace nutritious foods in diet, it can lead to poor nutrition and poor health in digestive and cardiovascular systems, respiratory system, and central nervous system. The effects of fast food on the body are related to the formation of excess free radicals. These free radicals are a kind of cellular "exhaust" a by-product of metabolism. Free radicals are produced as cells use oxygen to convert the food into energy. The body is designed to deal with these free radicals. It has highly efficient ways of grabbing and neutralizing these renegade particles before they can do harm. The free radicals that occur naturally within the body didn’t cause damage, but the excess of the free radicals is the cause of life-shortening damage. This extra load results from two key factors: an overabundance of toxins and a shortage of antioxidants. Antioxidants is the key to prevent the damage of free radicals by neutralizing their effect to prevent them from harming the body. The purpose of this review is to highlight the three main areas of research, which are interlinked. Study involving fast foods, free radicals and antioxidants. So, the objective of this study was to study the harmful effects of fast foods which related to the formation of excess amount of free radicals and provide a better insight into the mechanisms of antioxidants in prevention the damage of free radicals on the body.
Fast Foods, Free Radicals, Antioxidants, Healthy Foods
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Yomna Ali Moustafa Elkhateeb, Mona Rahil Alshammary, Effects of Fast Foods in Relation to Free Radicals and Antioxidants, American Journal of Laboratory Medicine. Vol. 2, No. 6, 2017, pp. 156-162. doi: 10.11648/j.ajlm.20170206.17
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Bagchi K, Puri S. Free radicals and antioxidants in health and disease. East Mediterranean Health Jr. 1998; 4: 350–60.
Aruoma OI. Nutrition and health aspects of free radicals and antioxidants. Food Chem Toxicol. 1994; 32: 671–83.
Cheeseman KH, Slater TF. An introduction to free radicals chemistry. Br Med Bull. 1993; 49: 481–93.
Young IS, Woodside JV. Antioxidants in health and disease. J Clin Pathol. 2001; 54: 176–86.
Harman D. Role of free radicals in aging and disease. Ann NY Acad Sci. 1992; 673: 126–41.
Rock CL, Jacob RA, Bowen PE. Update o biological characteristics of the antioxidant micronutrients- Vitamin C, Vitamin E and the carotenoids. J Am Diet Assoc. 1996; 96: 693–702.
Poppel GV, Golddbohm RA. Epidemiologic evidence for β – carotene and cancer prevention. Am J Clin Nutr. 1995; 62: 1393–5.
Halliwell B. How to characterize an antioxidant- An update. Biochem Soc Symp. 1995; 61: 73–101.
Shi HL, Noguchi N, Niki N. Comparative study on dynamics of antioxidative action of α- tocopheryl hydroquinone, ubiquinol and α- tocopherol, against lipid peroxidation. Free Radic Biol Med. 1999; 27: 334–46.
Levine M, Ramsey SC, Daruwara R. Criteria and recommendation for Vitamin C intake. JAMA. 1991; 281: 1415–23.
Rice-Evans CA, Diplock AT. Current status of antioxidant therapy. Free Radic Biol Med. 1993; 15: 77–96.
Krinsky NI. Mechanism of action of biological antioxidants. Proc Soc Exp Biol Med. 1992; 200: 248–54.
Zelko I, Mariani T, Folz R. Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med. 2002; 33: 337–49.
Banniste J, Bannister W, Rotilio G. Aspects of the structure, function, and applications of superoxide dismutase. CRC Crit Rev Biochem. 1987; 22: 111–80.
Johnson F, Giulivi C. Superoxide dismutases and their impact upon human health. Mol Aspects Med. 2005; 26: 340–52.
Chelikani P, Fita I, Loewen PC. Diversity of structures and properties among catalases. Cell Mol Life Sci. 2004; 61: 192–208.
Meister A, Anderson M. Glutathione. Annu Rev Biochem. 1983; 52: 711–60.
Hayes J, Flanagan J, Jowsey I. Glutathione transferases. Annu Rev Pharmacol Toxicol. 2005; 45: 51–88.
Padayatty S, Katz A, Wang Y, Eck P, Kwon O, Lee J, et al. Vitamin C as an antioxidant: Evaluation of its role in disease prevention. J Am Coll Nutr. 2003; 22: 18–35.
Shigeoka S, Ishikawa T, Tamoi M, Miyagawa Y, Takeda T, Yabuta Y, et al. Regulation and function of ascorbate peroxidase isoenzymes. J Exp Bot. 2002; 53: 1305–19.
Meister A, Anderson A. Glutathione. Annu Rev Biochem. 1983; 52: 711–60.
Herrera E, Barbas C. Vitamin E: Action, metabolism and perspectives. J Physiol Biochem. 2001; 57: 43–56.
Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Mechanisms of hepatotoxicity. Toxicol Sci. 2002; 65: 166–76.
Wang H, Cao G, Prior RL. Total antioxidant capacity of fruits. J Agric Food Chem. 1996; 44: 701–5.
Lin JK, Lin CH, Ling YC, Lin-Shian SY, Juan IM. Survey of catechins, gallic acid and methylxantines in green, oolong, puerh and black teas. J Agric Food Chem. 1998; 46: 3635–42.
Ifland JR, Preuss HG, Marcus MT, et al. Refined food addiction: a classic substance use disorder. Med Hypotheses 2009; 72 (5): 518- 26.
Wojnicki FH, Charny G, Corwin RL. Binge-type behavior in rats consuming trans-fat-free shortening. Physiol Behav 2008; 94 (4): 627-9.
Wojnicki FH, Johnson DS, Corwin RL. Access conditions affect binge type shortening consumption in rats. Physiol Behav 2008; 95 (5): 649- 57.
Avena NM, Rada P, Hoebel BG. Sugar and fat bingeing have notable differences in addictive-like behavior. J Nutr 2009; 139 (3): 623-8.
Blundell JE, Stubbs RJ, Golding C, et al. Resistance and susceptibility to weight gain: individual variability in response to a high-fat diet. Physiol Behav 2005; 86 (5): 614-22.
Griffiths RR, Vernotica EM. Is caffeine a flavoring agent in cola soft drinks? Arch Fam Med 2000; 9 (8): 727-34.
Nawrot P, Jordan S, Eastwood J, et al. Effects of caffeine on human health. Food Addit Contam 2003; 20 (1): 1-30.
Voorhies AC, Bernstein IL. Induction and expression of salt appetite: effects on Fos expression in nucleus accumbens. Behav Brain Res 2006; 172 (1): 90-6.
Lucas LR, Grillo CA, McEwen BS. Salt appetite in sodium-depleted or sodium-replete conditions: possible role of opioid receptors. Neuroendocrinology 2007; 85 (3): 139-47.
Cocores JA, Gold MS. The salted food addiction hypothesis may explain overeating and the obesity epidemic. Med Hypotheses 2009; 73 (6): 892-9.
Mani S. Production of reactive oxygen species and its implication in human diseases. In: Free Radicals in Human Health and Disease (V Rani, UCS Yadav). Springer, Berlin, Germany. 2015, p. 3‒15.
Pandey KB, Rizvi SI. Redox biology of aging: focus on novel biomarkers. In: Free Radicals in Human Health and Disease (V Rani, UCS Yadav). Springer, Berlin, Germany. 2015, p. 279‒90.
Berlett BS, Stadtman ER. Protein oxidation in aging, disease, and oxidative stress. J Biol Chem 1997; 272(33): 20313‒6.
Gupta RK, Patel AK, Shah N, Chaudhary AK, Jha UK, Yadav UC, et al. Oxidative stress and antioxidants in disease and cancer: a review. Asian Pac J Cancer Prev 2014; 15(11): 4405‒9.
Chou R, High Value Care Task Force of the American College of P. Cardiac screening with electrocardiography, stress echocardiography, or myocardial perfusion imaging: advice for high-value care from the American College of Physicians. Ann Intern Med 2015; 162(6): 438‒47.
Bagai A, Dangas GD, Stone GW, Granger CB. Reperfusion strategies in acute coronary syndromes. Circ Res 2014; 114(12): 1918‒28.
Arben Santo, Hong Zhu, and Y. Robert Li. Free Radicals: From Health to Disease. Reactive Oxygen Species 2016; 2(4): 245–263.
Lien Ai Pham-Huy, Hua He, and Chuong Pham-Huy. Free Radicals, Antioxidants in Disease and Health. Int J Biomed Sci. 4(2): 89–96, 2008.
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