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Software Development for Quantitative Analyzing of the Regulatory of Liver Cell and Hepatitis B Viruses by Using of Information Technologies

Received: 5 December 2017    Accepted: 15 December 2017    Published: 10 January 2018
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Abstract

In this article, the results on identifying of areas of homogeneous solutions of the functional-differential equations of the mathematical model of regulatory mechanisms of liver cell with hepatitis B viruses by constructing a parametric portrait using of modern information technology were presented. Typical phase trajectories were obtained using the object-oriented programming language Borland Delphi. The features of the area of the chaotic regime regulatory related activities of molecular genetic mechanisms of the liver cell and hepatitis B viruses by analyzing the dynamics of the Lyapunov exponent. Defined small regions with regular behavior ("r-windows") in the field of dynamic chaos. The regulatory of the liver cell and hepatitis B viruses can be moved from the region of dynamic chaos to normal region by using "r-windows".

Published in Software Engineering (Volume 5, Issue 6)
DOI 10.11648/j.se.20170506.11
Page(s) 81-87
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Regulatory Mechanisms, Mathematical and Computer Models, Qualitative and Quantitative Analysis, Parametric Portrait, Symbiosis, Chaos, Black Hole

References
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[2] Wiah E. N., Adetunde I. A., Brew L. (2012). Mathematical Modeling of the Interaction of Hepatitis B Virus with the Immune System Including the Effect of Therapy // International Journal of Modern Mathematical Sciences. 1 (2): 53-72.
[3] Elaiw A. M., Alghamdi M. A., Aly Sh. (2013). Hepatitis B Virus Dynamics: Modeling, Analysis, and Optimal Treatment Scheduling // Discrete Dynamics in Nature and Society. 9.
[4] Chen X., Sun K., Qiu J., Chen X., Yang Ch., Zhang A. (2014). Dynamics analysis of an amended HBV infection model with a simulation for anti-HBV infection therapy // Proceedings of the 33rd Chinese Control Conference. Nanjing. China. 2829-2834.
[5] Mboya K., Makinde D. O., Massawe E. S. (2015). Cytotoxic Cells and Control Strategies are Effective in Reducing the HBV Infection through a Mathematical Modelling // International Journal of Prevention and Treatment. 4 (3): 48-57.
[6] Stanca M. C., Ruy M. R., Alan S. P. (2014). Antibody Responses during Hepatitis B Viral Infection // PLoS Comput Biol. 10 (7): 1-16.
[7] Laarabi H., Abta A., Rachik M. and Rouyaghroumni J. (2013). Optimal antiviral treatment strategies of HBV infection model with logistic hepatocytes growth. ISRN Biomathematics.
[8] Plaire T. M., Jean J. T., Boulchard M., Bowong S. (2015). Mathematical analysis of the effect of a pulse vaccination to an HBV mutation // ARIMA Journal. 21: 3-19.
[9] Nowak M. A., Bangham C. R. M. (1996). Population dynamics of immune responses to persistent viruses. Science 272: 74-79.
[10] Hidirov B. N. (2014). Selected works on mathematical modeling of the regulatory of living systems. Moscow: Izhevsk. 304.
[11] Hidirov B. N., Turgunov A. M. (2010). Mathematical modeling of regulatory mechanisms for the development of viral hepatitis B // Questions of computational and applied mathematics. Tashkent. 125: 153-160.
[12] Hidirov B. N., Turgunov A. M. (2012). Modeling of molecular genetics mechanisms of control of viral hepatitis B. Uzbek journal of the Problems of Informatics and Energetics. 2-3: 13-18.
[13] Bellman R., Cooke K. (1963). Differential Difference Equations. Academic Press. 548.
[14] Saidalieva M., Hidirova M. B., Turgunov A. M. (2014). Areas of homogeneous solutions of the equations of the mathematical model of the regulatory of liver in hepatitis B. Uzbek journal of the Problems of Informatics and Energetics. 6: 3-8.
[15] Saidalieva M., Hidirova M. B., Turgunov A. M. (2015). Modeling of the regulatory of the liver cell in the quasi-stationary state of the hepatitis B virus. Scientific - technical and information-analytical journal TUIT - TUIT BULLETIN. 3 (35)/2015: 160-165.
[16] Hidirova M. B., Turgunov A. M. (2015). Computer modeling of infectious disease with viral hepatitis B using information technologies. Materials of the XV International Scientific and Methodical Conference "Informatics: Problems, Methodology, Technologies". 1: 478-481.
[17] Turgunov A. (2017). Analysis of the regulatory of the liver cell and hepatitis B viruses using a computer model. Collection of reports of the republican scientific and technical conference "The importance of information and communication technologies in the innovative development of real sectors of the economy". 1: 263-265.
[18] Turgunov A. M. (2017). On the modeling of regulatory of the liver cell and hepatitis B viruses. Scientific journal "Problems of computational and applied mathematics". 4 (10): 53-62.
[19] Hidirova M. B. (2014). On the solutions of the functional differential equation of the regulatory of living systems // Bulletin of the Moscow University series 1. Mathematics. Mechanics. 1: 50-52.
[20] Turgunov A. M. (2017). Characteristic regimes of the behavior of solutions of the regulator equations of the "Hepatocyte-HBV" system. Materials of the XVII International Scientific and Methodical Conference "Informatics: Problems, Methodology, Technologies". 2: 446-450.
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  • APA Style

    Mahruy Saidalieva, Mohiniso Baxromovna Hidirova, Abrorjon Maxamatsoliyevich Turgunov. (2018). Software Development for Quantitative Analyzing of the Regulatory of Liver Cell and Hepatitis B Viruses by Using of Information Technologies. Software Engineering, 5(6), 81-87. https://doi.org/10.11648/j.se.20170506.11

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    ACS Style

    Mahruy Saidalieva; Mohiniso Baxromovna Hidirova; Abrorjon Maxamatsoliyevich Turgunov. Software Development for Quantitative Analyzing of the Regulatory of Liver Cell and Hepatitis B Viruses by Using of Information Technologies. Softw. Eng. 2018, 5(6), 81-87. doi: 10.11648/j.se.20170506.11

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    AMA Style

    Mahruy Saidalieva, Mohiniso Baxromovna Hidirova, Abrorjon Maxamatsoliyevich Turgunov. Software Development for Quantitative Analyzing of the Regulatory of Liver Cell and Hepatitis B Viruses by Using of Information Technologies. Softw Eng. 2018;5(6):81-87. doi: 10.11648/j.se.20170506.11

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  • @article{10.11648/j.se.20170506.11,
      author = {Mahruy Saidalieva and Mohiniso Baxromovna Hidirova and Abrorjon Maxamatsoliyevich Turgunov},
      title = {Software Development for Quantitative Analyzing of the Regulatory of Liver Cell and Hepatitis B Viruses by Using of Information Technologies},
      journal = {Software Engineering},
      volume = {5},
      number = {6},
      pages = {81-87},
      doi = {10.11648/j.se.20170506.11},
      url = {https://doi.org/10.11648/j.se.20170506.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.se.20170506.11},
      abstract = {In this article, the results on identifying of areas of homogeneous solutions of the functional-differential equations of the mathematical model of regulatory mechanisms of liver cell with hepatitis B viruses by constructing a parametric portrait using of modern information technology were presented. Typical phase trajectories were obtained using the object-oriented programming language Borland Delphi. The features of the area of the chaotic regime regulatory related activities of molecular genetic mechanisms of the liver cell and hepatitis B viruses by analyzing the dynamics of the Lyapunov exponent. Defined small regions with regular behavior ("r-windows") in the field of dynamic chaos. The regulatory of the liver cell and hepatitis B viruses can be moved from the region of dynamic chaos to normal region by using "r-windows".},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Software Development for Quantitative Analyzing of the Regulatory of Liver Cell and Hepatitis B Viruses by Using of Information Technologies
    AU  - Mahruy Saidalieva
    AU  - Mohiniso Baxromovna Hidirova
    AU  - Abrorjon Maxamatsoliyevich Turgunov
    Y1  - 2018/01/10
    PY  - 2018
    N1  - https://doi.org/10.11648/j.se.20170506.11
    DO  - 10.11648/j.se.20170506.11
    T2  - Software Engineering
    JF  - Software Engineering
    JO  - Software Engineering
    SP  - 81
    EP  - 87
    PB  - Science Publishing Group
    SN  - 2376-8037
    UR  - https://doi.org/10.11648/j.se.20170506.11
    AB  - In this article, the results on identifying of areas of homogeneous solutions of the functional-differential equations of the mathematical model of regulatory mechanisms of liver cell with hepatitis B viruses by constructing a parametric portrait using of modern information technology were presented. Typical phase trajectories were obtained using the object-oriented programming language Borland Delphi. The features of the area of the chaotic regime regulatory related activities of molecular genetic mechanisms of the liver cell and hepatitis B viruses by analyzing the dynamics of the Lyapunov exponent. Defined small regions with regular behavior ("r-windows") in the field of dynamic chaos. The regulatory of the liver cell and hepatitis B viruses can be moved from the region of dynamic chaos to normal region by using "r-windows".
    VL  - 5
    IS  - 6
    ER  - 

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Author Information
  • Scientific and Innovation Center of Information and Communication Technologies, Tashkent University of Information Technologies Named After Muhammad Al-Khwarizmi, Tashkent, Uzbekistan

  • Scientific and Innovation Center of Information and Communication Technologies, Tashkent University of Information Technologies Named After Muhammad Al-Khwarizmi, Tashkent, Uzbekistan

  • Scientific and Innovation Center of Information and Communication Technologies, Tashkent University of Information Technologies Named After Muhammad Al-Khwarizmi, Tashkent, Uzbekistan

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