Thermal and Spectral Characterization of Cr(III), Co(II) and Cd(II) Metal Complexes Containing Bis-Imine Novel Schiff Base Ligand Towards Potential Biological Application
Chemical and Biomolecular Engineering
Volume 2, Issue 1, March 2017, Pages: 41-50
Received: Jan. 7, 2017; Accepted: Jan. 21, 2017; Published: Feb. 24, 2017
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Authors
Md. Saddam Hossain, Department of Chemistry, University of Rajshahi, Rajshai, Bangladesh
Shudeepta Sarker, Department of Chemistry, University of Rajshahi, Rajshai, Bangladesh
A. S. M. Elias Shaheed, Department of Chemistry, University of Rajshahi, Rajshai, Bangladesh
Md. Mamun Hossain, Department of Pharmacy, University of Rajshahi, Rajshai, Bangladesh
Abdul Alim-Al-Bari, Department of Pharmacy, University of Rajshahi, Rajshai, Bangladesh
Md. Rabiul Karim, Department of Chemistry, University of Rajshahi, Rajshai, Bangladesh
C. M. Zakaria, Department of Chemistry, University of Rajshahi, Rajshai, Bangladesh
Md. Kudrat-E-Zahan, Department of Chemistry, University of Rajshahi, Rajshai, Bangladesh
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Abstract
Metal complexes of Cr(III), Co(II) and Cd(II) ions were synthesizedwith a ONS containing Schiff base ligand, 2-bis(2-oxoindolin-3-ylidene)hydrazinecarbothioamide which was derived from the condensation reaction of thiosemicarbazide and isatin. The ligand and complexes were isolated from the reaction in the solid form and characterized by IR, UV-Visible, Thermal analysis and some physical measurements. Spectroscopic evidence indicated that the Schiff base behaved as ONS coordinating hexadentate chelating agent. Magnetic susceptibility data coupled with electronic spectra suggested a distorted octahedral structure of the complexes. The overall reaction was monitored by TLC and UV-Visible spectral analysis. The Schiff base and their metal complexes have been shown moderate to strong microbial activity.
Keywords
Transition Metal Complex, IR, UV-Visible Spectra Analysis, Antibacterial Activity, Schiff Base, TGA and DTG
To cite this article
Md. Saddam Hossain, Shudeepta Sarker, A. S. M. Elias Shaheed, Md. Mamun Hossain, Abdul Alim-Al-Bari, Md. Rabiul Karim, C. M. Zakaria, Md. Kudrat-E-Zahan, Thermal and Spectral Characterization of Cr(III), Co(II) and Cd(II) Metal Complexes Containing Bis-Imine Novel Schiff Base Ligand Towards Potential Biological Application, Chemical and Biomolecular Engineering. Vol. 2, No. 1, 2017, pp. 41-50. doi: 10.11648/j.cbe.20170201.16
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Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
B. Lakshmi, K. N. Shivananda, Gouda AvajiPrakash, Krishna Reddy K. Rama, and K. N. Mahendra,( 2011). Synthesis of Co(II), Ni(II) and Cu(II) Complexes from Schiff base Ligand and Reactivity Studies with Thermosetting Epoxy Resin. Bull. Korean Chem. Soc. 32 (5), 1613
[2]
Li-Yan Lai, Zheng Liu, Guo-Cheng Han, Zhencheng Chen., Springer, J Clust Sci. 2015, 26: 1845–1855.
[3]
Wilfredo Hernández, Juan Paz, Fernando Carrasco, Abraham Vaisberg, Evgenia Spodine, Jorge Manzur, Lothar Hennig, Joachim Sieler, Steffen Blaurock, and Lothar Beyer. Synthesis and Characterization of New Palladium(II) Thiosemicarbazone Complexes and Their Cytotoxic Activity against Various Human Tumor Cell Lines” Volume 2013, Article ID 524701, 12 pages.
[4]
Salman A. Khan, AbdullahM. Asiri, Khalid Al-Amry, andMaqsood AhmadMalik “Synthesis, Characterization, Electrochemical Studies, and In Vitro Antibacterial Activity of Novel Thiosemicarbazone and Its Cu(II), Ni(II), and Co(II) Complexes” Volume 2014, Article ID 592375, 9 pages.
[5]
T. P. Yoon, E. N. Jacobsen, (2003). Science 299: 1691.
[6]
T. Yamada, T. Ikeno, Y. Ohtsuka, S. Kezuka, M. Sato, I. Iwakura, (2006). Sci. Technol. Adv. Mater. 7, 184.
[7]
Y. P. Cai, C. Y. Su, A. W. Xu, B. S. Kang, H. Q. Liu, S. Jie, (2001). Polyhedron 20, 657.
[8]
A. A. El-Asmy and G. A. A. Al-Hazmi, (2009). Synthesis and spectral feature of benzophenone-substituted thiosemicarbazones and their Ni(II) and Cu(II) complexes. SpectrochimicaActa A, 71 (5): 1885–1890.
[9]
T. A. Yousef, G. M. Abu El-Reash, O. A. El-Gammal, and R. A. Bedier, (2012). Co(II), Cu(II), Cd(II), Fe(III) and U(VI) complexes containing a NSNO donor ligand: synthesis, characterization, optical band gap, in vitro antimicrobial and DNA cleavage studies. Journal of Molecular Structure, 1029 (12): 149–159.
[10]
W. Liu, X. Li, Z. Li, M. Zhang, and M. Song, (2007). Voltammetric metal cation sensors based on ferrocenyl thiosemicarbazone. Inorganic Chemistry Communications. 10 (12): 1485–1488.
[11]
S.-M. Ying, (2012). Synthesis, crystal structure and nonlinear optical property of a Zinc(II) complex base on the reduced Schiff-base ligand. Inorganic Chemistry Communications, 22: 82-84.
[12]
C. Agatha Christiea, C. Shijub and T. F. Abbs Fen Rejia. (2016). SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND BIOLOGICAL ACTIVITIES OF CO(II), NI(II), CU(II) AND ZN(II) COMPLEXES OF SCHIFF BASE DERIVED FROM ISATIN MONOHYDRAZONE AND FURFURALDEHYDE” jpmr, 3 (20: 238-244.
[13]
Sridhar, S. K.; Pandeya, S. N.; Stables, J. P. and Ramesh, A. (2002). Eur. J. Pharm. Sci. 16: 129
[14]
Penthala, N. R.; Yerramreddy, T. R.; Madadi, N. R. and Crooks, P. A (2010). Bioorg. Med. Chem. Lett., 20 (15): 4468
[15]
Pandeya, S. N.; Smitha, S.; Jyoti, M. and Sridhar, S. K.( 2005)Acta Pharm., 55: 27
[16]
Chiyanzu, I.; Hansell, E. and Gut, J. Bioorg.( 2003). Med. Chem. Lett. 13: 3527.
[17]
Chohan, Z. H., Pervez, H. and Rauf, A. J. Enz. Inhib. (2004). Med. Chem., 19: 417.
[18]
Md. Shiraj-U-Ddaula, Md. Anarul Islam, Shejutyaktar, Md. Khairul Islam, Md. Abdul Alim Al-Bari, Md. MasuqulHaque and Md. Kudrat-E-Zahan, 92014). Synthesis, Characterization and Antimicrobial Activity of Cd(II), Ni(II), Co(II) and Zr(IV) Metal Complexes of Schiff Base Ligand Derived from Diethylenetriamine and Isatin. Asian J. Research Chem. 7 (7): 619-621.
[19]
Bertrand, J. A.; Breece, J. L; Kalynaraman, A. R. Long, G. J. Bakes, W. A. J. Am (1970). Chem. Soc.92: 5233.
[20]
ZahidH. Chohan, Asifa Munawar and Claudiu T. Supuran (2001). Transition metal complexes of some Schiff bases synthesis characterization and antibacterial studies. 8 (3).
[21]
Moamen S. Refat, H. K. Ibrahim, S. Z. A. Sowellim, M. H. Soliman, E. M. Saeed. (2009). Spectroscopic and Thermal Studies of Mn(II), Fe(III), Cr(III) and Zn(II) Complexes Derived from the Ligand Resulted by the Reaction Between 4-Acetyl Pyridine and Thiosemicarbazide. Springer, J Inorg Organomet Polym 19: 521–531.
[22]
Ahmed Jasim M. Al-Karawi, (2009). Synthesis and characterization of a new N2S2 Schiff base ligand and its complexes with nickel(II), copper(II) and cadmium(II) including the kinetics of complex formation. Springer, Transition Met Chem 34: 891–897.
[23]
Md. Saddam Hossain, Md. Ashraful Islam, C. M. Zakaria, M. M. Haque, Md. Abdul Mannan, Md. Kudrat-E-Zahan. (2016). Synthesis, Spectral and Thermal Characterization with Antimicrobial Studies on Mn(II), Fe(II), Co(II) and Sn(II) Complexes of Tridentate N,O Coordinating Novel Schiff Base Ligand” J. Chem. Bio. Phy. Sci. Sec. A,. 6 (1): 041-052.
[24]
M. R. Islam, J. A. Shampa, M. Kudrat-E-Zahan, M. M. Haque, Y. Reza., (2016). J. Sci. Res., 8 (2), 181-189.
[25]
Md. Saddam Hossain, C. M. Zakaria, M. M. Haque and Md. Kudrat-E- Zahan, (2016) “Spectral and Thermal Characterization with Antimicrobial Activity on Cr(III) and Sn(II) Complexes containing N,O Donor Novel Schiff Base Ligand” IJCS, 4 (6): 08-11.
[26]
Alghool S, El-Halim HFA, El-sadek MA, Yahia I, Wahab L, (2015). Mononuclear complexes based on reduced Schiff base derived from L-methionine, synthesis, characterization, thermal and in vitro antimicrobial studies. J Therm Anal Calorim., 121: 1309–1319.
[27]
N. Padma Priya, S Arunachalam, A. Manimaran. D. Muthipriya. C. JayabalakrIshananSpectrochim. Acta A 72 (2009) 670-676.
[28]
M. R. Maurya, A. Kumar, M. Abid, and A. Azam,( 2006). Dioxovanadium (V) and 𝜇-oxobis[oxovanadium(V)] complexes containing thiosemicarbazone based ONS donor set and their antiamoebic activity. Inorganica Chimica Acta, 359 (8): 2439–2447.
[29]
S. Padhye, A. Zahra, S. Ekk et al., (2005). Synthesis and characterization of copper(II) complexes of 4-alkyl/aryl- 1,2-naphthoquinones thiosemicarbazones derivatives as potent DNA cleaving agents. Inorganica Chimica Acta, 358 (6): 2023–2030.
[30]
R. P. Gupta and N. L. Narayana, (1997). Synthesis of some Mannich bases of 1-cyclohexylidene-N (1,2-dihydro-2-oxo-3H-indol-3-ylidene) thiosemicarbazones and their antibacterial activity, Pharmaceutical Acta Helvetiae, 72 (1): 43–45.
[31]
T. A. Yousef, G. M. Abu El-Reash, O. A. El-Gammal, and R. A. Bedier, (2012). Co(II), Cu(II), Cd(II), Fe(III) and U(VI) complexes containing a NSNO donor ligand: synthesis, characterization, optical band gap, in vitro antimicrobial and DNA cleavage studies. Journal of Molecular Structure, 1029 (12): 149–159.
[32]
Moamen S. Refat, H. K. Ibrahim, S. Z. A. Sowellim, M. H. Soliman, E. M. Saeed, (2009) Spectroscopic and Thermal Studies of Mn(II), Fe(III), Cr(III) and Zn(II) Complexes Derived from the Ligand Resulted by the Reaction Between 4-Acetyl Pyridine and Thiosemicarbazide. Springer, J InorgOrganomet Polym., 19: 521–531.
[33]
Xinde Zhu, Chenggang Wang, Zhiping Lu and Yuanlin Dang, (1997). Synthesis, characterization and biological activity of the Schiff base derived from 3, 4-dihydroxybenzaldehyde and thiosemicarbazide, and its complexes with nickel(II) and iron(II). Springer, Transition Met. Chem., 22: 9-13.
[34]
T. Rosu, A. Gulea, A. Nicolae, and R. Georgescu, (2007). Complexes of 3dn metal ions with thiosemicarbazones: synthesis and Bioinorganic Chemistry and Applications 11 antimicrobial activity. Molecules, 12 (4): 782–796.
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