Chemical Pathology of Chemerin and Its Link to Obesity and Type 2 Diabetes Mellitus: A Review
Biochemistry and Molecular Biology
Volume 2, Issue 4, July 2017, Pages: 37-39
Received: Apr. 29, 2017;
Accepted: Jun. 1, 2017;
Published: Jul. 14, 2017
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Ekpe E. E., Department of Chemical Pathology, University of Calabar Teaching Hospital, Calabar, Nigeria
Ekpe V. E., Dornsife School of Public Health, Drexel University, Philadelphia, USA
Adipocytokines have been widely recognized in scientific research in recent times because of their varied functions and roles in the body. One of such recognized adipocytokines, is chemerin. A review of chemerin, is presented in this paper with a view to assessing the pathophysiology involved in obesity and type 2 diabetes mellitus. Published literatures were analyzed with the aim of assessing the correlation of chemerin in relation to obesity and diabetes mellitus. Searched literatures and journals from various researchers conclude with the evidence of increased levels of chemerin in type 2 diabetes mellitus patients which might play a major role in the pathogenesis of obesity and type 2 diabetes mellitus. Further studies are needed to understand the factors correlating chemerin levels to obesity and type 2diabetesmellitus. This could enhance pharmacologic management of diabetic and obese patients.
Ekpe E. E.,
Ekpe V. E.,
Chemical Pathology of Chemerin and Its Link to Obesity and Type 2 Diabetes Mellitus: A Review, Biochemistry and Molecular Biology.
Vol. 2, No. 4,
2017, pp. 37-39.
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