Biochemistry and Molecular Biology

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Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts

Received: 08 September 2017    Accepted: 08 October 2017    Published: 11 November 2017
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Abstract

Leaves of Luffa acutangular are consumed in some parts of Nigeria as part of folk medicine for the treatment of diseases and as a vegetable food source. This study was undertaken to evaluate the phytochemical constituents from ethanol extracts, antimicrobial resistance, proximate and mineral analysis of its leaf extracts. The phytochemical investigation revealed the presence of alkaloids, phenols, saponins, tannins, terpenoids, and triterpenoids. The elemental analysis of the dried leaf revealed the presence of Calcium (58.6 mg/g), Copper (0.6 mg/g), Magnesium (12.4 mg/g), Manganese (0.9 mg/g), Zinc (0.6 mg/g), Sodium (14.4 mg/g) and Potassium (143.6 mg/g) respectively. The samples were screened against Staphylococcus aureus, Staphylococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, Candida albicans and Candida tropicalis for their anti-microbial activity using Ciprofloxacin, Streptomycin and Fluconazole as control. Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) values were determined. Proximate analysis revealed moisture content of 10.6%, ash 6.3%, crude protein 2.6%, crude fiber 4.0%, fat 5.1% and carbohydrate content of 71.4%. The study showed that the leaf extract of L. acutangular may be used to manage some common diseases caused by the tested organisms. The major antimicrobial activity is tailored to the phyto-constituents. This confirms the folkloric use of the plants in the management of various diseases.

DOI 10.11648/j.bmb.20170206.13
Published in Biochemistry and Molecular Biology (Volume 2, Issue 6, November 2017)
Page(s) 80-85
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Luffa acutangular, Phytochemical Constituents, Antimicrobial Activities, AAS, Proximate Analysis

References
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Author Information
  • Biotechnology Advanced Research Centre, Sheda Science and Technology Complex, Abuja, Nigeria; Department of Biosciences, Salem University, Lokoja, Nigeria

  • Biotechnology Advanced Research Centre, Sheda Science and Technology Complex, Abuja, Nigeria

  • Biotechnology Advanced Research Centre, Sheda Science and Technology Complex, Abuja, Nigeria

  • Biotechnology Advanced Research Centre, Sheda Science and Technology Complex, Abuja, Nigeria

  • Department of Biotechnology, Modibbo Adama University of Technology, Yola, Nigeria

  • Department of Biotechnology, Modibbo Adama University of Technology, Yola, Nigeria

Cite This Article
  • APA Style

    Alagbe Seyi Valerie, Ibi Anna, Toge Christal, Amuzie Uzo Felicia, Ftepti Benson Jelani, et al. (2017). Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts. Biochemistry and Molecular Biology, 2(6), 80-85. https://doi.org/10.11648/j.bmb.20170206.13

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    ACS Style

    Alagbe Seyi Valerie; Ibi Anna; Toge Christal; Amuzie Uzo Felicia; Ftepti Benson Jelani, et al. Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts. Biochem. Mol. Biol. 2017, 2(6), 80-85. doi: 10.11648/j.bmb.20170206.13

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    AMA Style

    Alagbe Seyi Valerie, Ibi Anna, Toge Christal, Amuzie Uzo Felicia, Ftepti Benson Jelani, et al. Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts. Biochem Mol Biol. 2017;2(6):80-85. doi: 10.11648/j.bmb.20170206.13

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  • @article{10.11648/j.bmb.20170206.13,
      author = {Alagbe Seyi Valerie and Ibi Anna and Toge Christal and Amuzie Uzo Felicia and Ftepti Benson Jelani and Raji Bamanga},
      title = {Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts},
      journal = {Biochemistry and Molecular Biology},
      volume = {2},
      number = {6},
      pages = {80-85},
      doi = {10.11648/j.bmb.20170206.13},
      url = {https://doi.org/10.11648/j.bmb.20170206.13},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.bmb.20170206.13},
      abstract = {Leaves of Luffa acutangular are consumed in some parts of Nigeria as part of folk medicine for the treatment of diseases and as a vegetable food source. This study was undertaken to evaluate the phytochemical constituents from ethanol extracts, antimicrobial resistance, proximate and mineral analysis of its leaf extracts. The phytochemical investigation revealed the presence of alkaloids, phenols, saponins, tannins, terpenoids, and triterpenoids. The elemental analysis of the dried leaf revealed the presence of Calcium (58.6 mg/g), Copper (0.6 mg/g), Magnesium (12.4 mg/g), Manganese (0.9 mg/g), Zinc (0.6 mg/g), Sodium (14.4 mg/g) and Potassium (143.6 mg/g) respectively. The samples were screened against Staphylococcus aureus, Staphylococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, Candida albicans and Candida tropicalis for their anti-microbial activity using Ciprofloxacin, Streptomycin and Fluconazole as control. Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) values were determined. Proximate analysis revealed moisture content of 10.6%, ash 6.3%, crude protein 2.6%, crude fiber 4.0%, fat 5.1% and carbohydrate content of 71.4%. The study showed that the leaf extract of L. acutangular may be used to manage some common diseases caused by the tested organisms. The major antimicrobial activity is tailored to the phyto-constituents. This confirms the folkloric use of the plants in the management of various diseases.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Antimicrobial and Physicochemical Evaluation of Luffa acutangular Leaf Extracts
    AU  - Alagbe Seyi Valerie
    AU  - Ibi Anna
    AU  - Toge Christal
    AU  - Amuzie Uzo Felicia
    AU  - Ftepti Benson Jelani
    AU  - Raji Bamanga
    Y1  - 2017/11/11
    PY  - 2017
    N1  - https://doi.org/10.11648/j.bmb.20170206.13
    DO  - 10.11648/j.bmb.20170206.13
    T2  - Biochemistry and Molecular Biology
    JF  - Biochemistry and Molecular Biology
    JO  - Biochemistry and Molecular Biology
    SP  - 80
    EP  - 85
    PB  - Science Publishing Group
    SN  - 2575-5048
    UR  - https://doi.org/10.11648/j.bmb.20170206.13
    AB  - Leaves of Luffa acutangular are consumed in some parts of Nigeria as part of folk medicine for the treatment of diseases and as a vegetable food source. This study was undertaken to evaluate the phytochemical constituents from ethanol extracts, antimicrobial resistance, proximate and mineral analysis of its leaf extracts. The phytochemical investigation revealed the presence of alkaloids, phenols, saponins, tannins, terpenoids, and triterpenoids. The elemental analysis of the dried leaf revealed the presence of Calcium (58.6 mg/g), Copper (0.6 mg/g), Magnesium (12.4 mg/g), Manganese (0.9 mg/g), Zinc (0.6 mg/g), Sodium (14.4 mg/g) and Potassium (143.6 mg/g) respectively. The samples were screened against Staphylococcus aureus, Staphylococcus pneumonia, Streptococcus pyrogens, Klebsciella pneumonia, Candida albicans and Candida tropicalis for their anti-microbial activity using Ciprofloxacin, Streptomycin and Fluconazole as control. Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) values were determined. Proximate analysis revealed moisture content of 10.6%, ash 6.3%, crude protein 2.6%, crude fiber 4.0%, fat 5.1% and carbohydrate content of 71.4%. The study showed that the leaf extract of L. acutangular may be used to manage some common diseases caused by the tested organisms. The major antimicrobial activity is tailored to the phyto-constituents. This confirms the folkloric use of the plants in the management of various diseases.
    VL  - 2
    IS  - 6
    ER  - 

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