The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People
Science Journal of Public Health
Volume 2, Issue 2, March 2014, Pages: 64-68
Received: Jan. 3, 2014; Published: Feb. 20, 2014
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Authors
UURTUYA Shuumarjav, Department of Physiology and Pathophysiology, School of Biomedicine, HSUM;Department of Clinical Laboratory Medicine, Jichi Medical University, Japan
KAZUHIKO Kotani, Department of Clinical Laboratory Medicine, Jichi Medical University, Japan
NYAMDORJ Dagdanbazar, Department of Human Anatomy, School of Biomedicine, HSUM
NOBUYUKI Taniguchi, Department of Clinical Laboratory Medicine, Jichi Medical University, Japan
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Abstract
Mongolian people suffer from atherosclerotic diseases more than Japanese people, while both people are thought to share similar genetic background under different lifestyles and environments. Comparative studies using novel atherosclerotic parameters of Mongolian and Japanese people may demonstrate the atherosclerotic features of both populations. We have recently reported the findings regarding atherosclerosis of both populations using circulating high sensitivity C-reactive protein (CRP: as low-grade inflammatory parameter) and cardio-ankle vascular index (CAVI: as arterial stiffness parameter), herein summarizing the data. Our studies revealed that in comparison to the Japanese subjects, the Mongolian subjects had higher levels of CRP and CAVI, in addition to a higher percentage of current smoking and higher levels of body mass index, heart rate and blood pressure and insulin, even though there were not so higher levels of serum total cholesterol and glucose. These results were confirmed in healthy young subjects and patients with hypertension and diabetes mellitus. These comparative studies used recent parameters suggest that Mongolian people may be at higher risk for cardiovascular disease than Japanese people. The management strategies of atherosclerotic diseases are also expected in the near future.
Keywords
Atherosclerosis, Altitude, Ethnic, Cardio-Ankle Vascular Index, C-Reactive Protein
To cite this article
UURTUYA Shuumarjav, KAZUHIKO Kotani, NYAMDORJ Dagdanbazar, NOBUYUKI Taniguchi, The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People, Science Journal of Public Health. Vol. 2, No. 2, 2014, pp. 64-68. doi: 10.11648/j.sjph.20140202.14
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