The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People

UURTUYA Shuumarjav; KAZUHIKO Kotani; NYAMDORJ Dagdanbazar; NOBUYUKI Taniguchi

doi:doi:10.11648/j.sjph.20140202.14

| Peer-Reviewed

The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People

UURTUYA Shuumarjav, KAZUHIKO Kotani, NYAMDORJ Dagdanbazar, NOBUYUKI Taniguchi

Published in Science Journal of Public Health (Volume 2, Issue 2)

Received: 3 January 2014 Accepted: Published: 20 February 2014

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Mongolian people suffer from atherosclerotic diseases more than Japanese people, while both people are thought to share similar genetic background under different lifestyles and environments. Comparative studies using novel atherosclerotic parameters of Mongolian and Japanese people may demonstrate the atherosclerotic features of both populations. We have recently reported the findings regarding atherosclerosis of both populations using circulating high sensitivity C-reactive protein (CRP: as low-grade inflammatory parameter) and cardio-ankle vascular index (CAVI: as arterial stiffness parameter), herein summarizing the data. Our studies revealed that in comparison to the Japanese subjects, the Mongolian subjects had higher levels of CRP and CAVI, in addition to a higher percentage of current smoking and higher levels of body mass index, heart rate and blood pressure and insulin, even though there were not so higher levels of serum total cholesterol and glucose. These results were confirmed in healthy young subjects and patients with hypertension and diabetes mellitus. These comparative studies used recent parameters suggest that Mongolian people may be at higher risk for cardiovascular disease than Japanese people. The management strategies of atherosclerotic diseases are also expected in the near future.

Published in	Science Journal of Public Health (Volume 2, Issue 2)
DOI	10.11648/j.sjph.20140202.14
Page(s)	64-68
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Atherosclerosis, Altitude, Ethnic, Cardio-Ankle Vascular Index, C-Reactive Protein

References

[1]	World Health Organization. Preventing chronic disease: a vital investment. Geneva, WHO, 2005.
[2]	Mayer L. Bacic-Vrca V, Sulentic P, Sisic I, Maric-Miholic, Romovski S, Ljubic D. Correlation of cardio-ankle vascular index, ten-year risk assessment and other atherosclerosis risk factors. Coll Antropol 2011; 35:167-172.
[3]	Kim KJ, Lee BW, Kim HM, Shin JY, Kang ES, Cha BS, Lee EJ, Lim SK, Lee HC. Associations between cardio-ankle vascular index and microvascular complications in type 2 diabetes mellitus patients. J Atheroscler Thromb 2011; 18:328-336.
[4]	Pasceri V. Willerson JT and Yeh ET. Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation 2000; 102:2165-2168.
[5]	Ridker PM, Cushman MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk cardiovascular disease in apparently healthy men. N Engl J Med 1997; 336:973-979.
[6]	Koeng W, Sund M, Frohlich M, Fischer H, Lowel H, Doring A, et al. C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men. Circulation 1999; 99:237-242.
[7]	Uurtuya S, Taniguchi N, Kotani, K, et al. Comparative study of the cardio-ankle vascular index and ankle-brachial index between young Japanese and Mongolian subjects. Hypertens Res 2009; 32:140-144.
[8]	Uurtuya SH, Kotani K, Tanigichi N, et al. Comparative study of the atherosclerotic parameters in Mongolian and Japanese patients with hypertension and diabetes mellitus. J Atheroscler Thromb 2010; 17:181-188.
[9]	Uurtuya S, Kotani K, Taniguchi N. Association between serum C-reactive protein and metabolic syndrome in Mongolian patients in comparison to Japanese patients. Ethn Dis 2011; 21:74-78.
[10]	Anuuraad E, Shiwaku K, Nogi A. Ethnic differences in the formation of small LDL particles in Asians: a comparison of Koreans, Japanese and Mongolians. Eur J Clin Invest 34:738-746, 2004.
[11]	Uurtuya S, Kotani K, Yoshioka H, Yamada T, Taniguchi N. Determinants of carotid atherosclerosis in the general Mongolian population. Ethnicity & Disease 2010; 20:257-260.
[12]	Implementing agency of the government of Mongolia. Department of health. Health Indicators. 2008; pp38.
[13]	Sekikawa A, Kuller LH, Ueshima H, et al. Coronary heart disease mortality trends in men in the post World War II birth cohorts aged 35-44 in Japan, South Korea and Taiwan compared with the Unites States. Int J Epidemiol, 1999; 28:1044-1049.
[14]	Ueshima H. Chnages in Dietery habits, cardiovascular risk factors and mortality in Japan. Acta Cardiol 1990; 45:311-327.
[15]	World Health Ranking 2009. http://www.worldlifeexpectancy.com/country-health-profile/
[16]	World Health Organization. Country Health Information Profiles: 2009 Revision. WHO, Western pacific region. 2009.
[17]	Implementing agency of the government of Mongolia. Department of health. Health Indicators. 2008; pp38.
[18]	Komatsu F, Hasegawa K, Yanagisawa Y, et al. Prevalence of Diego Blood Group Dia antigen in Mongolians: Comparison with that in Japanese. Transfus Apher Sci 30: 119-124, 2004.
[19]	Takaki A, Ogawa H, Wakeyama A, et al. Cardio-ankle vascular index is superior to brachial-ankle pulse wave velocity as an index of arterial stiffness. Hypertens Res 2008; 31:1347-55.
[20]	Othuka K, Norboo T, Otsuka Y, et al. Chronoecological health watch of arterial stiffness and neuro-cardio-pulmonary function in elderly community at high altitude (3524m), compared with Japanese town. Biomed Pharmacother 59:S58-S67, 2005.
[21]	Kotani K, Michiaki Miyamoto and Nobuyuki Taniguchi. Clinical significance of the cardio-ankle vascular index (CAVI) in Hypertension. Current Hypertension Reviews 2010; 6:251-253.
[22]	Izuhara M, Shioji K, Kadota S, et al. Relationship of cardio-ankle vascular index (CAVI) to carotid and coronary arteriosclerosis. Circ J 2008; 72:1762-7.
[23]	Sanders PW. Vascular consequences of dietary salt intake. Am J Physiol Renal Physiol 2009; 297:F237-43.
[24]	Kim KJ, Lee BW, Kim HM, et al. Association between cardio-ankle vascular index and microvascular complications in type 2 diabetes. J Atheroscler Thromb 2011;
[25]	Pepys MB. The acute phase response and C-reactive protein. Oxford Textbook of Medice. New York, Oxford University 1996; p1527-33.
[26]	Torzewski J, Torzewski M, Bowyer DE, et al. C-reactive protein frequently colocalizes with terminal complement complex in the intima of early atherosclerotic lesions of human coronary arteries. Arterioscler Thromb Vasc Biol 1998; 18:1386-1392.
[27]	WHO factsheet on cardiovascular disease. Last accessed at http://www.who.int/mediacentre/factsheets/fs317/en/index. html 12August 2010
[28]	Komatsu F, Kagawa Y, Kawabata T, et al. Dietary habits of Mongolian people, and their influence on lifestyle-related diseases and early aging. Curr Aging Sci 2008; 1:84-100.
[29]	United Nations Children’s Fund (UNICEF). Nutrition status of population of Mongolia 2000. Ulaanbaatar, Second National Nutrition Survey; 2002.
[30]	The National Nutrition Survey in Japan 2000. The Ministry of Heath, Labor and Welfare, Japan; 2002.
[31]	Nogi A, Yang J, Li L, et al. Plasma n-3 fatty acid and cardiovascular disease risk factors in Japanese, Korean and Mongolian workers. J Occup Health 2007; 49:205-216.
[32]	Olziikhutag A: Adaptation of aboriginal inhabitants and regional pathology in condition of Mongolian median altitude. Ulaanbaatar. Mongolia. pp299-317, 2000.
[33]	Melicher .V, Novak P, Novak M, Hahn P and Koldovsky O. Blood cholesterol levels in newborn infants and adults in Ulaanbaatar (Mongolia) and Prague (Czechoslovakia). Nutr Dieta 1965; 7:191-195.
[34]	Woo KS, Chook P, Raiakari OT et al., Westernization of Chinese adults and increased subclinical atherosclerosis. Arterioscler Thromb Vasc Biol. 1999; 19:2487-2493.
[35]	Choo J, Usechima H, Jang V, et al. Difference in carotid intima-media thickness between Korean and Japanese men. Ann Epidemiol 2008; 18:310-315.
[36]	Schindler T. H, Cardenas J, Prior J. O, et al. Relationship between increasing body weight, insulin resistance, inflammation, adipocytokine leptin, and coronary circulatory function. J Am Coll Cardiol 2006; 47:1188-1195.
[37]	Castillo O, Woolcott OO, Gonzalis E, et al. Residents at high altitude show a lower glucose profile than sea-level residents throughout 12-hour blood continuous monitoring. High Alt Med Biol 2007; 8:307-311.

Cite This Article

Plain Text BibTeX RIS

APA Style

UURTUYA Shuumarjav, KAZUHIKO Kotani, NYAMDORJ Dagdanbazar, NOBUYUKI Taniguchi. (2014). The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People. Science Journal of Public Health, 2(2), 64-68. https://doi.org/10.11648/j.sjph.20140202.14

Copy | Download

ACS Style

UURTUYA Shuumarjav; KAZUHIKO Kotani; NYAMDORJ Dagdanbazar; NOBUYUKI Taniguchi. The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People. Sci. J. Public Health 2014, 2(2), 64-68. doi: 10.11648/j.sjph.20140202.14

Copy | Download

AMA Style

UURTUYA Shuumarjav, KAZUHIKO Kotani, NYAMDORJ Dagdanbazar, NOBUYUKI Taniguchi. The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People. Sci J Public Health. 2014;2(2):64-68. doi: 10.11648/j.sjph.20140202.14

Copy | Download

@article{10.11648/j.sjph.20140202.14,
  author = {UURTUYA Shuumarjav and KAZUHIKO Kotani and NYAMDORJ Dagdanbazar and NOBUYUKI Taniguchi},
  title = {The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People},
  journal = {Science Journal of Public Health},
  volume = {2},
  number = {2},
  pages = {64-68},
  doi = {10.11648/j.sjph.20140202.14},
  url = {https://doi.org/10.11648/j.sjph.20140202.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20140202.14},
  abstract = {Mongolian people suffer from atherosclerotic diseases more than Japanese people, while both people are thought to share similar genetic background under different lifestyles and environments.  Comparative studies using novel atherosclerotic parameters of Mongolian and Japanese people may demonstrate the atherosclerotic features of both populations. We have recently reported the findings regarding atherosclerosis of both populations using circulating high sensitivity C-reactive protein (CRP: as low-grade inflammatory parameter) and cardio-ankle vascular index (CAVI: as arterial stiffness parameter), herein summarizing the data.  Our studies revealed that in comparison to the Japanese subjects, the Mongolian subjects had higher levels of CRP and CAVI, in addition to a higher percentage of current smoking and higher levels of body mass index, heart rate and blood pressure and insulin, even though there were not so higher levels of serum total cholesterol and glucose. These results were confirmed in healthy young subjects and patients with hypertension and diabetes mellitus.  These comparative studies used recent parameters suggest that Mongolian people may be at higher risk for cardiovascular disease than Japanese people. The management strategies of atherosclerotic diseases are also expected in the near future.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People
AU  - UURTUYA Shuumarjav
AU  - KAZUHIKO Kotani
AU  - NYAMDORJ Dagdanbazar
AU  - NOBUYUKI Taniguchi
Y1  - 2014/02/20
PY  - 2014
N1  - https://doi.org/10.11648/j.sjph.20140202.14
DO  - 10.11648/j.sjph.20140202.14
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 64
EP  - 68
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20140202.14
AB  - Mongolian people suffer from atherosclerotic diseases more than Japanese people, while both people are thought to share similar genetic background under different lifestyles and environments.  Comparative studies using novel atherosclerotic parameters of Mongolian and Japanese people may demonstrate the atherosclerotic features of both populations. We have recently reported the findings regarding atherosclerosis of both populations using circulating high sensitivity C-reactive protein (CRP: as low-grade inflammatory parameter) and cardio-ankle vascular index (CAVI: as arterial stiffness parameter), herein summarizing the data.  Our studies revealed that in comparison to the Japanese subjects, the Mongolian subjects had higher levels of CRP and CAVI, in addition to a higher percentage of current smoking and higher levels of body mass index, heart rate and blood pressure and insulin, even though there were not so higher levels of serum total cholesterol and glucose. These results were confirmed in healthy young subjects and patients with hypertension and diabetes mellitus.  These comparative studies used recent parameters suggest that Mongolian people may be at higher risk for cardiovascular disease than Japanese people. The management strategies of atherosclerotic diseases are also expected in the near future.
VL  - 2
IS  - 2
ER  -

Copy | Download

Author Information

UURTUYA Shuumarjav

Department of Physiology and Pathophysiology, School of Biomedicine, HSUM;Department of Clinical Laboratory Medicine, Jichi Medical University, Japan
KAZUHIKO Kotani

Department of Clinical Laboratory Medicine, Jichi Medical University, Japan
NYAMDORJ Dagdanbazar

Department of Human Anatomy, School of Biomedicine, HSUM
NOBUYUKI Taniguchi

Department of Clinical Laboratory Medicine, Jichi Medical University, Japan

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

UURTUYA Shuumarjav, KAZUHIKO Kotani, NYAMDORJ Dagdanbazar, NOBUYUKI Taniguchi. (2014). The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People. Science Journal of Public Health, 2(2), 64-68. https://doi.org/10.11648/j.sjph.20140202.14

Copy | Download

ACS Style

UURTUYA Shuumarjav; KAZUHIKO Kotani; NYAMDORJ Dagdanbazar; NOBUYUKI Taniguchi. The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People. Sci. J. Public Health 2014, 2(2), 64-68. doi: 10.11648/j.sjph.20140202.14

Copy | Download

AMA Style

UURTUYA Shuumarjav, KAZUHIKO Kotani, NYAMDORJ Dagdanbazar, NOBUYUKI Taniguchi. The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People. Sci J Public Health. 2014;2(2):64-68. doi: 10.11648/j.sjph.20140202.14

Copy | Download

@article{10.11648/j.sjph.20140202.14,
  author = {UURTUYA Shuumarjav and KAZUHIKO Kotani and NYAMDORJ Dagdanbazar and NOBUYUKI Taniguchi},
  title = {The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People},
  journal = {Science Journal of Public Health},
  volume = {2},
  number = {2},
  pages = {64-68},
  doi = {10.11648/j.sjph.20140202.14},
  url = {https://doi.org/10.11648/j.sjph.20140202.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20140202.14},
  abstract = {Mongolian people suffer from atherosclerotic diseases more than Japanese people, while both people are thought to share similar genetic background under different lifestyles and environments.  Comparative studies using novel atherosclerotic parameters of Mongolian and Japanese people may demonstrate the atherosclerotic features of both populations. We have recently reported the findings regarding atherosclerosis of both populations using circulating high sensitivity C-reactive protein (CRP: as low-grade inflammatory parameter) and cardio-ankle vascular index (CAVI: as arterial stiffness parameter), herein summarizing the data.  Our studies revealed that in comparison to the Japanese subjects, the Mongolian subjects had higher levels of CRP and CAVI, in addition to a higher percentage of current smoking and higher levels of body mass index, heart rate and blood pressure and insulin, even though there were not so higher levels of serum total cholesterol and glucose. These results were confirmed in healthy young subjects and patients with hypertension and diabetes mellitus.  These comparative studies used recent parameters suggest that Mongolian people may be at higher risk for cardiovascular disease than Japanese people. The management strategies of atherosclerotic diseases are also expected in the near future.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - The C-Reactive Protein and Cardio-Ankle Vascular index of Mongolian and Japanese People
AU  - UURTUYA Shuumarjav
AU  - KAZUHIKO Kotani
AU  - NYAMDORJ Dagdanbazar
AU  - NOBUYUKI Taniguchi
Y1  - 2014/02/20
PY  - 2014
N1  - https://doi.org/10.11648/j.sjph.20140202.14
DO  - 10.11648/j.sjph.20140202.14
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 64
EP  - 68
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20140202.14
AB  - Mongolian people suffer from atherosclerotic diseases more than Japanese people, while both people are thought to share similar genetic background under different lifestyles and environments.  Comparative studies using novel atherosclerotic parameters of Mongolian and Japanese people may demonstrate the atherosclerotic features of both populations. We have recently reported the findings regarding atherosclerosis of both populations using circulating high sensitivity C-reactive protein (CRP: as low-grade inflammatory parameter) and cardio-ankle vascular index (CAVI: as arterial stiffness parameter), herein summarizing the data.  Our studies revealed that in comparison to the Japanese subjects, the Mongolian subjects had higher levels of CRP and CAVI, in addition to a higher percentage of current smoking and higher levels of body mass index, heart rate and blood pressure and insulin, even though there were not so higher levels of serum total cholesterol and glucose. These results were confirmed in healthy young subjects and patients with hypertension and diabetes mellitus.  These comparative studies used recent parameters suggest that Mongolian people may be at higher risk for cardiovascular disease than Japanese people. The management strategies of atherosclerotic diseases are also expected in the near future.
VL  - 2
IS  - 2
ER  -

Copy | Download