Little epidermiological data is available on the prevalence of HIV, Hepatitis B and C, Co-and or triple infection during pregnancy in Cameroon as well as many other resource limited settings. HIV and Hepatitis B and C are major public health concerns world wide. Our study aimed at assessing the seroprevalence of Hepatitis B and C amongst HIV infected pregnant women in Buea, located in the Southwest region of Cameroon. A Cross-sectional study on consented pregnant women were conducted from March 2015 to August 2015. HIV-1 infections were detected using the national HIV-1 test algorithms. Hepatitis B surface antigen (HBsAg), anti-HBe and anti- Hepatitis C (anti-HCV) were detected using Enzyme linked Immunosorbent Assays (ELISAs). Of the 1230 recruited pregnant women, 97/1230 (7.8%) (95% CI: 3.5, 29.0%) were confirmed HIV-1 positive. HIV/HBV co-infection were observed in 14/97 (14.4%) (95% CI: 39.8, 100%), whilst 11/97 (11.3 %; 95% CI: 27.5, 100%) were HIV/HCV co-infections. Two HIV-infected pregnant women (8/97(8.2%; 95% CI: 0.1, 17.2%)) were HIV/HBV/HCV triple-infected. Anti-HBc was detected in all HBV-infected pregnant women (14/14; (100.0%)) (95.0% CI: 39.8, 100.0%). Seropositivity for HIV-1 was higher (37%) amongst subjects aged between 32-37 years, whilst none was found above 40. From our results we conclude that Co- and triple infections of HIV, Hepatitis B and C were present amongst pregnant women in Buea. Epidemiological data generated from this study are limited due to the existence of triple infected. It will therefore serve as a guide to the government policies to reinforce screening, treatment and prevention strategies, through its Mother–to-Child–transmission (pMTCT) Programme nationwide.
| Published in | Science Journal of Public Health (Volume 4, Issue 2) |
| DOI | 10.11648/j.sjph.20160402.17 |
| Page(s) | 127-131 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Hepatitis B and C, Cameroon, Co-infection
| [1] | WHO: Hepatitis B. Fact Sheet No. 204. Geneva, Switzerland: World Health Organization; 2014. Teo E-K, Lok ASF: Epidemiology, transmission, and prevention of hepatitis B virus infection. In UpToDate. Edited by Basow DS. Waltham, MA: UpToDate; 2009. WHO: Hepatitis B vaccines. |
| [2] | F, Keugoung B, Fouedjio JH, Kouam N, Mendibi S, DongtsaMabou J: High Rates of Hepatitis B and C and HIV Infections among Blood Donors in Cameroon: A Proposed Blood Screening Algorithm for Blood Donors in Resource-Limited Settings. J Blood Transfus 2012, 2012: 1-7. |
| [3] | Noubiap JJN, Joko WYA, Nansseu JRN, Tene UG, Siaka C: Sero-epidemiology of human immunodeficiency virus, hepatitis B and C viruses, and syphilis infections among first-time blood donors in Edéa, Cameroon. Int J Infect Dis 2013, 17:e832-e837. PubMed Abstract | Publisher Full Text . |
| [4] | Euler GL, Wooten KG, Baughman AL, Williams WW: Hepatitis B surface antigen prevalence among pregnant women in urban areas: implications for testing, reporting, and preventing perinatal transmission. Pediatrics 2003, 11: 1192-1197. |
| [5] | Gutierrez, R. Garcia, E. Ntsama, C. Parra-Fariñas, M. C. Fariñas and C. Fariñas-Alvarez HBV, HIV seroprevalence high among pregnant women at Cameroon clinic. |
| [6] | Chiaramonte M, Stroffolini T, Ngatchu T, Rapicetta M, Lantum D, Kaptue L, Chionne P, Conti S, Sarrecchia B, Naccarato R: Hepatitis B virus infection in Cameroon: a seroepidemiological survey in city school children. J Med Virol 1991, 33: 95-99. |
| [7] | Njouom R, Pasquier C, Ayouba A, Tejiokem MC, Vessiere A, Mfoupouendoun J, Tene G, Eteki N, Lobe MM, Izopet J: Low risk of mother-to-child transmission of hepatitis C virus in Yaounde, Cameroon: the ANRS 1262 study. Am J Trop Med Hyg 2005, 73: 460-466. PubMed Abstract | Publisher Full Text . |
| [8] | Fomulu NJ, Morfaw FL, Torimiro JN, Nana P, Koh MV, William T: Prevalence, correlates and pattern of Hepatitis B among antenatal clinic attenders in Yaounde-Cameroon: is perinatal transmission of HBV neglected in Cameroon? BMC Pregnancy Childbirth 2013, 13: 1-10. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text. |
| [9] | Frambo AA, Atashili J, Fon PN, Ndumbe PM: Prevalence of HBsAg and knowledge about hepatitis B in pregnancy in the Buea Health District, Cameroon: a cross-sectional study. BMC 2014 Jun 25; 7: 394. doi: 10.1186/1756-0500-7-394. |
| [10] | Parry E, Godfrey R, Mabey D, Gill G: Hepatitis Viruses. In Princ Med Afr. 3rd edition. Cambridge: Cambridge University Press; 2009: 710-712. |
| [11] | Collenberg, T. Ouedraogo, J. Ganame, H. Fickenscher, G. Kynast-Wolf, H. Becher, et al. Seroprevalence of six different viruses among pregnant women and blood donors in rural and urban Burkina Faso: a comparative analysis, J Med Virol, 78 (2006), pp. 683–692. |
| [12] | J. Simpore, D. Ilboudo, A. Samandoulougou, P. Guardo, P. Castronovo, S. Musumeci HCV and HIV co-infection in pregnant women attending St. Camille Medical Centre in Ouagadougou (Burkina Faso)J Med Virol, 75 (2005), pp. 209–212. |
| [13] | J. Simpore, M. Granato, R. Santarelli, R. A. Nsme, M. Coluzzi, V. Pietra, et al. Prevalence of infection by HHV-8, HIV, HCV and HBV among pregnant women in Burkina Faso J Clin Virol, 31 (2004), pp. 78–80. |
| [14] | C. Laurent, A. Bourgeois, M. Mpoudi, C. Butel, E. Mpoudi-Ngole, E. Delaporte HIV and hepatitis C virus coinfection, Cameroon Emerg Infect Dis, 13 (2007), pp. 514–516. |
| [15] | D. N. Mbanya, D. Takam, P. M. Ndumbe Serological findings amongst first-time blood donors in Yaounde, Cameroon: is safe donation a reality or a myth? Transfus Med, 13 (2003), pp. 267–273. |
| [16] | J. M. Pawlotsky, L. Belec, G. Gresenguet, L. Deforges, M. Bouvier, J. Duval, et al. High prevalence of hepatitis B, C, and E markers in young sexually active adults from the Central African Republic J Med Virol, 46 (1995), pp. 269–272. |
| [17] | C. Laurent, D. Henzel, C. Mulanga-Kabeya, G. Maertens, B. Larouze, E. Delaporte Seroepidemiological survey of hepatitis C virus among commercial sex workers and pregnant women in Kinshasa, Democratic Republic of Congo Int J Epidemiol, 30 (2001), pp. 872–877. |
| [18] | F. Rouet, M. L. Chaix, A. Inwoley, P. Msellati, I. Viho, P. Combe, et al. HBV and HCV prevalence and viraemia in HIV-positive and HIV-negative pregnant women in Abidjan, Cote d’Ivoire: the ANRS 1236 study J Med Virol, 74 (2004), pp. 34–40. |
| [19] | P. Combe, G. La Ruche, D. Bonard, T. Ouassa, H. Faye-Ketté, F. Sylla-Koko, et al. Hepatitis B and C infections, human immunodeficiency virus and other sexually transmitted infections among women of childbearing age in Cote d’Ivoire, West Africa. |
| [20] | Obi SN, Onah HE, Ezugwu FO: Risk factors for hepatitis B infection during pregnancy in a Nigerian obstetric population. J ObstetGynecol 2006, 26: 770-772. Publisher Full Text . |
| [21] | Kfutwah AK, Tejiokem MC, Njouom R: A low proportion of HBeAg among HBsAg-positive pregnant women with known HIV status could suggest low perinatal transmission of HBV in Cameroon. Virol J 2012, 9: 422X-9. |
| [22] | Ndumbe PM, Skalsky J, Joller-Jemelka H: Seroprevalence of hepatitis and HIV infection among rural pregnant women in Cameroon. Apmis 1994, 102: 662-666. PubMed Abstract | Publisher Full Text . |
| [23] | Okoth F, Mbuthia J, Gatheru Z, Murila F, Kanyingi F, Mugo F, Esamai F, Alavi Z, Otieno J, Kiambati H: Seroprevalence of hepatitis B markers in pregnant women in Kenya. East Afr Med J 2009, 83: 485-493. |
| [24] | Okada K, Kamiyama I, Inomata M, Imai M, Miyakawa Y, Mayumi M: e antigen and anti-e in the serum of asymptomatic carrier mothers as indicators of positive and negative transmission of hepatitis B virus to their infants. N Engl J Med 1976, 294: 746-749. |
APA Style
George Mondinde Ikomey, Graeme Brendon Jacobs, Becky Tanjong, Martha Tongo Mesembe, Agnes Eyoh, et al. (2016). Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon. Science Journal of Public Health, 4(2), 127-131. https://doi.org/10.11648/j.sjph.20160402.17
ACS Style
George Mondinde Ikomey; Graeme Brendon Jacobs; Becky Tanjong; Martha Tongo Mesembe; Agnes Eyoh, et al. Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon. Sci. J. Public Health 2016, 4(2), 127-131. doi: 10.11648/j.sjph.20160402.17
AMA Style
George Mondinde Ikomey, Graeme Brendon Jacobs, Becky Tanjong, Martha Tongo Mesembe, Agnes Eyoh, et al. Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon. Sci J Public Health. 2016;4(2):127-131. doi: 10.11648/j.sjph.20160402.17
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.sjph.20160402.17,
author = {George Mondinde Ikomey and Graeme Brendon Jacobs and Becky Tanjong and Martha Tongo Mesembe and Agnes Eyoh and Emilia Lyonga and Ebot Mfoataw and Rose Ngoh and Cynthia Raissa Tamandjou and Greg Ikomey and Marie Claire Okomo Assoumou},
title = {Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon},
journal = {Science Journal of Public Health},
volume = {4},
number = {2},
pages = {127-131},
doi = {10.11648/j.sjph.20160402.17},
url = {https://doi.org/10.11648/j.sjph.20160402.17},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20160402.17},
abstract = {Little epidermiological data is available on the prevalence of HIV, Hepatitis B and C, Co-and or triple infection during pregnancy in Cameroon as well as many other resource limited settings. HIV and Hepatitis B and C are major public health concerns world wide. Our study aimed at assessing the seroprevalence of Hepatitis B and C amongst HIV infected pregnant women in Buea, located in the Southwest region of Cameroon. A Cross-sectional study on consented pregnant women were conducted from March 2015 to August 2015. HIV-1 infections were detected using the national HIV-1 test algorithms. Hepatitis B surface antigen (HBsAg), anti-HBe and anti- Hepatitis C (anti-HCV) were detected using Enzyme linked Immunosorbent Assays (ELISAs). Of the 1230 recruited pregnant women, 97/1230 (7.8%) (95% CI: 3.5, 29.0%) were confirmed HIV-1 positive. HIV/HBV co-infection were observed in 14/97 (14.4%) (95% CI: 39.8, 100%), whilst 11/97 (11.3 %; 95% CI: 27.5, 100%) were HIV/HCV co-infections. Two HIV-infected pregnant women (8/97(8.2%; 95% CI: 0.1, 17.2%)) were HIV/HBV/HCV triple-infected. Anti-HBc was detected in all HBV-infected pregnant women (14/14; (100.0%)) (95.0% CI: 39.8, 100.0%). Seropositivity for HIV-1 was higher (37%) amongst subjects aged between 32-37 years, whilst none was found above 40. From our results we conclude that Co- and triple infections of HIV, Hepatitis B and C were present amongst pregnant women in Buea. Epidemiological data generated from this study are limited due to the existence of triple infected. It will therefore serve as a guide to the government policies to reinforce screening, treatment and prevention strategies, through its Mother–to-Child–transmission (pMTCT) Programme nationwide.},
year = {2016}
}
TY - JOUR T1 - Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon AU - George Mondinde Ikomey AU - Graeme Brendon Jacobs AU - Becky Tanjong AU - Martha Tongo Mesembe AU - Agnes Eyoh AU - Emilia Lyonga AU - Ebot Mfoataw AU - Rose Ngoh AU - Cynthia Raissa Tamandjou AU - Greg Ikomey AU - Marie Claire Okomo Assoumou Y1 - 2016/03/28 PY - 2016 N1 - https://doi.org/10.11648/j.sjph.20160402.17 DO - 10.11648/j.sjph.20160402.17 T2 - Science Journal of Public Health JF - Science Journal of Public Health JO - Science Journal of Public Health SP - 127 EP - 131 PB - Science Publishing Group SN - 2328-7950 UR - https://doi.org/10.11648/j.sjph.20160402.17 AB - Little epidermiological data is available on the prevalence of HIV, Hepatitis B and C, Co-and or triple infection during pregnancy in Cameroon as well as many other resource limited settings. HIV and Hepatitis B and C are major public health concerns world wide. Our study aimed at assessing the seroprevalence of Hepatitis B and C amongst HIV infected pregnant women in Buea, located in the Southwest region of Cameroon. A Cross-sectional study on consented pregnant women were conducted from March 2015 to August 2015. HIV-1 infections were detected using the national HIV-1 test algorithms. Hepatitis B surface antigen (HBsAg), anti-HBe and anti- Hepatitis C (anti-HCV) were detected using Enzyme linked Immunosorbent Assays (ELISAs). Of the 1230 recruited pregnant women, 97/1230 (7.8%) (95% CI: 3.5, 29.0%) were confirmed HIV-1 positive. HIV/HBV co-infection were observed in 14/97 (14.4%) (95% CI: 39.8, 100%), whilst 11/97 (11.3 %; 95% CI: 27.5, 100%) were HIV/HCV co-infections. Two HIV-infected pregnant women (8/97(8.2%; 95% CI: 0.1, 17.2%)) were HIV/HBV/HCV triple-infected. Anti-HBc was detected in all HBV-infected pregnant women (14/14; (100.0%)) (95.0% CI: 39.8, 100.0%). Seropositivity for HIV-1 was higher (37%) amongst subjects aged between 32-37 years, whilst none was found above 40. From our results we conclude that Co- and triple infections of HIV, Hepatitis B and C were present amongst pregnant women in Buea. Epidemiological data generated from this study are limited due to the existence of triple infected. It will therefore serve as a guide to the government policies to reinforce screening, treatment and prevention strategies, through its Mother–to-Child–transmission (pMTCT) Programme nationwide. VL - 4 IS - 2 ER -
Information
Email: