Uses Impact of Betel Leaf (Piper betle L.) on Public Health
Science Journal of Public Health
Volume 5, Issue 6, November 2017, Pages: 408-410
Received: Sep. 26, 2015; Accepted: Oct. 11, 2015; Published: Sep. 13, 2017
Views 3407      Downloads 398
Md. Farid Hossain, School of Agriculture and Rural Development, Bangladesh Open University, Gazipur, Bangladesh
Mustafa Anwar, Department of Surgery, Ibn Sina Medical College and Hospital, Dhaka, Bangladesh
Shaheen Akhtar, Department of Community Medicine, Shahabuddin Medical College and Hospital, Dhaka, Bangladesh
Sharker Md. Numan, School of Science and Technology, Bangladesh Open University, Gazipur, Bangladesh
Article Tools
Follow on us
This review paper focus on the uses and health impact of betel leaf (Piper betle L.). The betel plant belongs to the family Piperaceae. Traditionally betel leaf is chewing after taking meal having significant medicinal properties and nutritional values. It contains some vitamins, minerals and produce enzyme that helps in digestion and work as mouth freshener. Literature shows that the leaf has a significant antimicrobial activity against broad spectrum of microorganisms. The betel leaf is predominantly consumed as betel quid, which is a mixture of substances areca nut, tobacco and lime. Some reports may suggest that betel quid has adverse health effects but most of the findings show that the betel leaf has many medicinal benefits and it has no adverse effects.
Betel Leaf, Betel Quid, Medicinal Value, Health Hazard, Importance
To cite this article
Md. Farid Hossain, Mustafa Anwar, Shaheen Akhtar, Sharker Md. Numan, Uses Impact of Betel Leaf (Piper betle L.) on Public Health, Science Journal of Public Health. Vol. 5, No. 6, 2017, pp. 408-410. doi: 10.11648/j.sjph.20170506.11
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Chakraborty, D. 2011. Antimicrobial, anti-oxidative, anti-hemolytic activity of Piper betle leaf extracts. International Journal of Pharmacy and Pharmaceutical Sciences. 3: 975-1491.
Husna, A. A.; Islam, M. A.; Rahman, T. and Khatun, M. M. 2015. Efficacy of vinegar, sorbitol and sodium benzoate in mitigation of Salmonella contamination in betel leaf. J. Adv. Vet. Anim. Res. 2 (2): 190-194.
Rai, M. P.; Thilakchand, K. R.; Palatty, P. L.; Rao, P.; Rao, S.; Bhat, H. P., Baliga, M. S. 2011. Piper betle Linn (Betel Vine), the Maligned Southeast Asian Medicinal Plant Possesses Cancer Preventive Effects: Time to Reconsider the Wronged Opinion. Asian Pacific Journal of Cancer Prevention. 12: 2149-2156.
Agarwal, T.; Singh, R.; Shukla, A. D.; Waris, I. and Gujrati, A. 2012. Comparative analysis of antibacterial activity of four Piper betle varieties. Advances in Applied Science Research. 3 (2): 698-705.
Jeng, J. H.; Chen, S. Y.; Liar, C. H.; Tung, Y. Y.; Lin, B. R.; Hahn, L. J. and Chang, M. C. 2002. Modulation of platelet aggregation by areca nut and betel leaf ingredients: Roles of relative oxygen species and cyclooxygenase. Free Radical Biology and Medicine, 32 (9): 860-871.
Guha, P. 2006. Betel leaf: The neglected green gold of India. J Hum Ecol. 19, 87-93.
Sugumaran, M.; Poornima M.; Venkatraman S.; Lakshmi M.; Srinivasansethuvani. 2011. “Chemical composition and antimicrobial activity of sirugamani variety of Piper betle Linn Leaf oil”, Journal of Pharmacy Research. 4 (10): 3424-3426.
Bajpai, V.; Sharma, D.; Kumar, B.; Madhusudanan, K. P. 2010. “Profiling of Piper betle Linn. Cultivars by direct analysis in real time mass spectrometric technique”, Biomedical Chromatography. 24 (12): 1283-1286.
Kumar, N.; Misra, P.; Dube, A. and others. 2010. Piper betle Linn. A maligned Pan-Asiatic plant with an array of pharmacological activities and prospects for drug discovery. Curr Sci. 99: 922-32.
Chaurasia, S.; Kulkurni, G. T.; and Setty, L. N. 2010. Phytochemical studies and invitro cytotoxicity screening of Piper betle leaf (PBL) extract, International Research Journal of Pharmacy. 1 (1): 384-391.
Ghosh, K. and Bhattacharya, T. K. 2005. Chemical Constituents of Piper betel Linn. (Piperaceae) roots. Molecules. 10: 798-802.
Fong, Y. S. 2009. Chemical constituents and biological activities of Garcinia mangostana and Piper betle. Master’s thesis, University Putra Malaysia, pp. 22.
Chandra, V.; Tripathi, S.; Verma, N. K.; Singh, D. P.; Chaudhary, S. K. and Roshan, A. 2011. Piper betle: phytochemistry, traditional use & pharmacological activity-a review. IJPRD. 4 (4): 216-223.
Arambewela, L.; Kumaratunga, K. G. A. and Dias, K. 2005. Studies on Piper betle of Sri Lanka. J. Natn. Sci. Foundation Sri Lanka. 33 (2): 133-139.
Arambewela, L. S. R.; Arawwawala, L. D. A. M.; Kumaratunga K. G.;, D. S., Ratnasooriya W. D.; Kumarasingha,, S. P. 2011. Investigations on Piper betel grown in Sri Lanka”, Pharmacogn. Rev. 5 (10): 159-163.
Dwivedi, B. K. and Mehta B. K. 2011. Chemical investigation of aliphatic compounds of Piper betle (leaf stalk). J. Nat. Prod. Plant Resour. 1 (2): 18-24.
Dwivedi, B. K.; Kumar, S.; Nayak, C. and Mehta B. K. 2010. Gas chromatography mass spectrometry (GCMS) analysis of the hexane and benzene extracts of the Piper betle (leaf stalk) (Family: Piperaceae) from India”, Journal of Medicinal Plants Research. 4 (21): 2252-2255.
Bissa, S.; Songara, D. and Bohra, A. 2007. Traditions in oral hygiene: Chewing of betel (Piper betle L.) leaves. Current Science. 92 (1): 26-28.
Sarkar, M.; Gangopadhyay, P. and Basak, B. 2000. The reversible antifertility activity of Piper betle Linn. on Swiss albino male mice. Contraception, 62: 271-274.
Rahman, S. A. 2009. Anti-ulcer effects of Piper betle, Solanum nigrum and Zingiber cassumunar on ulceration induced by selected ulcerogens in rats, Master’s thesis, University Putra Malaysia, pp. 4.
Pradhan, D.; Suri, K. A.; Pradhan, D. K. and Biswasroy, P. 2013. Golden Heart of the Nature: Piper betle L. Journal of Pharmacognosy and Phytochemistry. 1 (6): 147-167.
Jesonbabu, J. N. and Lakshmi, K. A. 2012. In vitro antimicrobial potentialities of chloroform extracts of Ethano-medicinal plant against clinically isolated human pathogens. International Journal of Pharmacy and Pharmaceutical Sciences. 4 (3): 624-626.
Chakraborty, D. and Shah, B. 2011. Antimicrobial, antioxidative and antihemolytic activity of Piper betle leaf extracts. International Journal of Pharmaceutical Technology. 3 (3): 192-199.
Agarwal, T. and Singh, R. 2012. Evaluation of Antimicrobial Activity of Piper betel cultivars, International Journal of Pharmaceutical Technology. 1 (1): 50-58.
Bangash, F. A.; Hashmi A. N.; Mahboob A.; Zahid, M.; Hamid B.; Muhammad, S. A.; Shah, Z. U. and Afzaal, H. 2012. In-vitro antibacterial activity of piper betle leaf extracts. J App Pharm. 3 (4): 639-646.
Chopra, R. N. and Chopra I. C. 1958. Indigenous Drugs of India. Pub- Academic Publishers 2nd Edition. pp. 372.
Fathilah, A. R.; Sujata, R.; Norhanom, A. W. and Adenan, M. I. 2010. Antiproliferative activity of aqueous extract of Piper betel L. and Psidium guajava L. on KB and HeLa cell lines. Journal of Medicinal Plants Research. 4 (11): 987-990.
Yang, Mei-Sang; Lee, Chien-Hung; Chang, Shun-Jen; Chung, Tieh-Chi; Tsai, Eing-Mei; Ko, Allen Min-Jen; Ko, Ying-Chin. 2008. "The effect of maternal betel quid exposure during pregnancy on adverse birth outcomes among aborigines in Taiwan". Drug and Alcohol Dependence. 95 (1-2): 134-9.
Senn, M.; Baiwog, F.; Winmai, J.; Mueller, I.; Rogerson, S.; Senn, N. 2009. "Betel nut chewing during pregnancy, Madang province, Papua New Guinea". Drug and Alcohol Dependence 105 (1-2): 126-31.
[31] po0115/leaves.
Toprani R. and Patel, D. 2013. Betel leaf: Revisiting the benefits of an ancient Indian herb. South Asian Journal of Cancer. 2 (3): 140-141.
Sekhar Namburi, U. R., Omprakash and Babu G. 2011. A review on management of warts in Ayurveda. Ayu. 32 (1): 100-102.
Arawwawala, L. D., Arambewela, L. S., Ratnasooriya, W. D. 2014. Gastro protective effect of Piper betle Linn. Leaves grown in Sri Lanka. J Ayurveda Integr. Med. 5 (1): 38-42.
Arambewela, L. S., Arawwawala, L. D., Ratnasooriya, W. D. 2005. Antidiabetic activities of aqueous and ethanolic extracts of Piper betle leave in rats. J Ethnopharmacol. 102 (2): 239-45.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186