The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction

Rongqin Dai; Zhenjiang Hou; Jingyu Zhang; Hong Fan; Hongsheng Wang; Jianzhang Hou

doi:doi:10.11648/j.sjph.20180602.14

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The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction

Rongqin Dai, Zhenjiang Hou, Jingyu Zhang, Hong Fan, Hongsheng Wang, Jianzhang Hou

Published in Science Journal of Public Health (Volume 6, Issue 2)

Received: 30 January 2018 Accepted: Published: 5 February 2018

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Abstract

The objective is to discuss about the correlation of Glycolipid Metabolism, Cystatin C (CysC) and Homocysteine (Hcy) of thyroid dysfunction. 100 cases of hyperthyroidism, hypothyroidism and the control group are chose respectively to measure Fiber Bragg Grating (FBG), Blood Lipid, Thyroid Hormone (TH), CysC and Hcy, calculate the blood lipid ratio and make analysis. As a result, Thyroid Carcinoma (TC), Thyroglobulin (TG), Low-density Lipoprotein Cholesterol (LDL-C), High-density Lipoprotein Cholesterol (HDL-C), TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, Lipid comprehensive index (LCI) and non-HDL-C of hyperthyroidism group are obviously lower than the control group. The decrease of LCI is the most prominent. Hcy is slightly lower than the control group. FBG and CysC are obviously higher than the control group. TC, TG, LDL-C, TG/HDL-C, LDL-C/HDL-C, LCI and non-HDL-C, Hcy of hypothyroidism group are higher than the control group (P＜0.05), and FBG, HDL-C and CysC are lower than the control group (P＜0.05). Various kinds of TH have the highest connection with TC, followed by non-HDL-C, LDL-C and LCI. It comes to the conclusion that patients with thyroid dysfunction easily appear the disorder of glucose and lipid metabolism. The change in blood lipid ratio is more pronounced than that of single lipid indicator and is closely related to CysC and Hcy. Dynamic monitoring of Thyroid Stimulating Hormone (TSH), blood lipid ratio, CysC and Hcy is of great value in the diagnosis of thyroid dysfunction and the prediction of Cardiovascular Disease (CVD) in concurrent Coronary Heart Disease (CHD) and so on.

Published in	Science Journal of Public Health (Volume 6, Issue 2)
DOI	10.11648/j.sjph.20180602.14
Page(s)	55-60
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Hyperthyroidism, Hypothyroidism, Blood Glucose, Blood Lipid Ratio, Cystain C, Homocysteine

References

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APA Style

Rongqin Dai, Zhenjiang Hou, Jingyu Zhang, Hong Fan, Hongsheng Wang, et al. (2018). The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction. Science Journal of Public Health, 6(2), 55-60. https://doi.org/10.11648/j.sjph.20180602.14

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ACS Style

Rongqin Dai; Zhenjiang Hou; Jingyu Zhang; Hong Fan; Hongsheng Wang, et al. The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction. Sci. J. Public Health 2018, 6(2), 55-60. doi: 10.11648/j.sjph.20180602.14

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AMA Style

Rongqin Dai, Zhenjiang Hou, Jingyu Zhang, Hong Fan, Hongsheng Wang, et al. The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction. Sci J Public Health. 2018;6(2):55-60. doi: 10.11648/j.sjph.20180602.14

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@article{10.11648/j.sjph.20180602.14,
  author = {Rongqin Dai and Zhenjiang Hou and Jingyu Zhang and Hong Fan and Hongsheng Wang and Jianzhang Hou},
  title = {The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction},
  journal = {Science Journal of Public Health},
  volume = {6},
  number = {2},
  pages = {55-60},
  doi = {10.11648/j.sjph.20180602.14},
  url = {https://doi.org/10.11648/j.sjph.20180602.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20180602.14},
  abstract = {The objective is to discuss about the correlation of Glycolipid Metabolism, Cystatin C (CysC) and Homocysteine (Hcy) of thyroid dysfunction. 100 cases of hyperthyroidism, hypothyroidism and the control group are chose respectively to measure Fiber Bragg Grating (FBG), Blood Lipid, Thyroid Hormone (TH), CysC and Hcy, calculate the blood lipid ratio and make analysis. As a result, Thyroid Carcinoma (TC), Thyroglobulin (TG), Low-density Lipoprotein Cholesterol (LDL-C), High-density Lipoprotein Cholesterol (HDL-C), TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, Lipid comprehensive index (LCI) and non-HDL-C of hyperthyroidism group are obviously lower than the control group. The decrease of LCI is the most prominent. Hcy is slightly lower than the control group. FBG and CysC are obviously higher than the control group. TC, TG, LDL-C, TG/HDL-C, LDL-C/HDL-C, LCI and non-HDL-C, Hcy of hypothyroidism group are higher than the control group (P＜0.05), and FBG, HDL-C and CysC are lower than the control group (P＜0.05). Various kinds of TH have the highest connection with TC, followed by non-HDL-C, LDL-C and LCI. It comes to the conclusion that patients with thyroid dysfunction easily appear the disorder of glucose and lipid metabolism. The change in blood lipid ratio is more pronounced than that of single lipid indicator and is closely related to CysC and Hcy. Dynamic monitoring of Thyroid Stimulating Hormone (TSH), blood lipid ratio, CysC and Hcy is of great value in the diagnosis of thyroid dysfunction and the prediction of Cardiovascular Disease (CVD) in concurrent Coronary Heart Disease (CHD) and so on.},
 year = {2018}
}

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TY  - JOUR
T1  - The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction
AU  - Rongqin Dai
AU  - Zhenjiang Hou
AU  - Jingyu Zhang
AU  - Hong Fan
AU  - Hongsheng Wang
AU  - Jianzhang Hou
Y1  - 2018/02/05
PY  - 2018
N1  - https://doi.org/10.11648/j.sjph.20180602.14
DO  - 10.11648/j.sjph.20180602.14
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 55
EP  - 60
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20180602.14
AB  - The objective is to discuss about the correlation of Glycolipid Metabolism, Cystatin C (CysC) and Homocysteine (Hcy) of thyroid dysfunction. 100 cases of hyperthyroidism, hypothyroidism and the control group are chose respectively to measure Fiber Bragg Grating (FBG), Blood Lipid, Thyroid Hormone (TH), CysC and Hcy, calculate the blood lipid ratio and make analysis. As a result, Thyroid Carcinoma (TC), Thyroglobulin (TG), Low-density Lipoprotein Cholesterol (LDL-C), High-density Lipoprotein Cholesterol (HDL-C), TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, Lipid comprehensive index (LCI) and non-HDL-C of hyperthyroidism group are obviously lower than the control group. The decrease of LCI is the most prominent. Hcy is slightly lower than the control group. FBG and CysC are obviously higher than the control group. TC, TG, LDL-C, TG/HDL-C, LDL-C/HDL-C, LCI and non-HDL-C, Hcy of hypothyroidism group are higher than the control group (P＜0.05), and FBG, HDL-C and CysC are lower than the control group (P＜0.05). Various kinds of TH have the highest connection with TC, followed by non-HDL-C, LDL-C and LCI. It comes to the conclusion that patients with thyroid dysfunction easily appear the disorder of glucose and lipid metabolism. The change in blood lipid ratio is more pronounced than that of single lipid indicator and is closely related to CysC and Hcy. Dynamic monitoring of Thyroid Stimulating Hormone (TSH), blood lipid ratio, CysC and Hcy is of great value in the diagnosis of thyroid dysfunction and the prediction of Cardiovascular Disease (CVD) in concurrent Coronary Heart Disease (CHD) and so on.
VL  - 6
IS  - 2
ER  -

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Author Information

Rongqin Dai

Institute of Thyroid Diseases, Cangzhou Medical College, Cangzhou, China
Zhenjiang Hou

Institute of Thyroid Diseases, Cangzhou Medical College, Cangzhou, China
Jingyu Zhang

Laboratory Diagnostics Division, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, China
Hong Fan

Laboratory Diagnostics Division, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, China
Hongsheng Wang

Laboratory Diagnostics Division, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, China
Jianzhang Hou

Department of Surgery, Cangzhou Medical College Hospital District of Cangzhou People's Hospital, Cangzhou, China

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APA Style

Rongqin Dai, Zhenjiang Hou, Jingyu Zhang, Hong Fan, Hongsheng Wang, et al. (2018). The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction. Science Journal of Public Health, 6(2), 55-60. https://doi.org/10.11648/j.sjph.20180602.14

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ACS Style

Rongqin Dai; Zhenjiang Hou; Jingyu Zhang; Hong Fan; Hongsheng Wang, et al. The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction. Sci. J. Public Health 2018, 6(2), 55-60. doi: 10.11648/j.sjph.20180602.14

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AMA Style

Rongqin Dai, Zhenjiang Hou, Jingyu Zhang, Hong Fan, Hongsheng Wang, et al. The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction. Sci J Public Health. 2018;6(2):55-60. doi: 10.11648/j.sjph.20180602.14

Copy | Download

@article{10.11648/j.sjph.20180602.14,
  author = {Rongqin Dai and Zhenjiang Hou and Jingyu Zhang and Hong Fan and Hongsheng Wang and Jianzhang Hou},
  title = {The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction},
  journal = {Science Journal of Public Health},
  volume = {6},
  number = {2},
  pages = {55-60},
  doi = {10.11648/j.sjph.20180602.14},
  url = {https://doi.org/10.11648/j.sjph.20180602.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20180602.14},
  abstract = {The objective is to discuss about the correlation of Glycolipid Metabolism, Cystatin C (CysC) and Homocysteine (Hcy) of thyroid dysfunction. 100 cases of hyperthyroidism, hypothyroidism and the control group are chose respectively to measure Fiber Bragg Grating (FBG), Blood Lipid, Thyroid Hormone (TH), CysC and Hcy, calculate the blood lipid ratio and make analysis. As a result, Thyroid Carcinoma (TC), Thyroglobulin (TG), Low-density Lipoprotein Cholesterol (LDL-C), High-density Lipoprotein Cholesterol (HDL-C), TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, Lipid comprehensive index (LCI) and non-HDL-C of hyperthyroidism group are obviously lower than the control group. The decrease of LCI is the most prominent. Hcy is slightly lower than the control group. FBG and CysC are obviously higher than the control group. TC, TG, LDL-C, TG/HDL-C, LDL-C/HDL-C, LCI and non-HDL-C, Hcy of hypothyroidism group are higher than the control group (P＜0.05), and FBG, HDL-C and CysC are lower than the control group (P＜0.05). Various kinds of TH have the highest connection with TC, followed by non-HDL-C, LDL-C and LCI. It comes to the conclusion that patients with thyroid dysfunction easily appear the disorder of glucose and lipid metabolism. The change in blood lipid ratio is more pronounced than that of single lipid indicator and is closely related to CysC and Hcy. Dynamic monitoring of Thyroid Stimulating Hormone (TSH), blood lipid ratio, CysC and Hcy is of great value in the diagnosis of thyroid dysfunction and the prediction of Cardiovascular Disease (CVD) in concurrent Coronary Heart Disease (CHD) and so on.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction
AU  - Rongqin Dai
AU  - Zhenjiang Hou
AU  - Jingyu Zhang
AU  - Hong Fan
AU  - Hongsheng Wang
AU  - Jianzhang Hou
Y1  - 2018/02/05
PY  - 2018
N1  - https://doi.org/10.11648/j.sjph.20180602.14
DO  - 10.11648/j.sjph.20180602.14
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 55
EP  - 60
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20180602.14
AB  - The objective is to discuss about the correlation of Glycolipid Metabolism, Cystatin C (CysC) and Homocysteine (Hcy) of thyroid dysfunction. 100 cases of hyperthyroidism, hypothyroidism and the control group are chose respectively to measure Fiber Bragg Grating (FBG), Blood Lipid, Thyroid Hormone (TH), CysC and Hcy, calculate the blood lipid ratio and make analysis. As a result, Thyroid Carcinoma (TC), Thyroglobulin (TG), Low-density Lipoprotein Cholesterol (LDL-C), High-density Lipoprotein Cholesterol (HDL-C), TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, Lipid comprehensive index (LCI) and non-HDL-C of hyperthyroidism group are obviously lower than the control group. The decrease of LCI is the most prominent. Hcy is slightly lower than the control group. FBG and CysC are obviously higher than the control group. TC, TG, LDL-C, TG/HDL-C, LDL-C/HDL-C, LCI and non-HDL-C, Hcy of hypothyroidism group are higher than the control group (P＜0.05), and FBG, HDL-C and CysC are lower than the control group (P＜0.05). Various kinds of TH have the highest connection with TC, followed by non-HDL-C, LDL-C and LCI. It comes to the conclusion that patients with thyroid dysfunction easily appear the disorder of glucose and lipid metabolism. The change in blood lipid ratio is more pronounced than that of single lipid indicator and is closely related to CysC and Hcy. Dynamic monitoring of Thyroid Stimulating Hormone (TSH), blood lipid ratio, CysC and Hcy is of great value in the diagnosis of thyroid dysfunction and the prediction of Cardiovascular Disease (CVD) in concurrent Coronary Heart Disease (CHD) and so on.
VL  - 6
IS  - 2
ER  -

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