The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction
Science Journal of Public Health
Volume 6, Issue 2, March 2018, Pages: 55-60
Received: Jan. 30, 2018; Published: Feb. 5, 2018
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Rongqin Dai, Institute of Thyroid Diseases, Cangzhou Medical College, Cangzhou, China
Zhenjiang Hou, Institute of Thyroid Diseases, Cangzhou Medical College, Cangzhou, China
Jingyu Zhang, Laboratory Diagnostics Division, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, China
Hong Fan, Laboratory Diagnostics Division, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, China
Hongsheng Wang, Laboratory Diagnostics Division, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Cangzhou, China
Jianzhang Hou, Department of Surgery, Cangzhou Medical College Hospital District of Cangzhou People's Hospital, Cangzhou, China
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The objective is to discuss about the correlation of Glycolipid Metabolism, Cystatin C (CysC) and Homocysteine (Hcy) of thyroid dysfunction. 100 cases of hyperthyroidism, hypothyroidism and the control group are chose respectively to measure Fiber Bragg Grating (FBG), Blood Lipid, Thyroid Hormone (TH), CysC and Hcy, calculate the blood lipid ratio and make analysis. As a result, Thyroid Carcinoma (TC), Thyroglobulin (TG), Low-density Lipoprotein Cholesterol (LDL-C), High-density Lipoprotein Cholesterol (HDL-C), TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, Lipid comprehensive index (LCI) and non-HDL-C of hyperthyroidism group are obviously lower than the control group. The decrease of LCI is the most prominent. Hcy is slightly lower than the control group. FBG and CysC are obviously higher than the control group. TC, TG, LDL-C, TG/HDL-C, LDL-C/HDL-C, LCI and non-HDL-C, Hcy of hypothyroidism group are higher than the control group (P<0.05), and FBG, HDL-C and CysC are lower than the control group (P<0.05). Various kinds of TH have the highest connection with TC, followed by non-HDL-C, LDL-C and LCI. It comes to the conclusion that patients with thyroid dysfunction easily appear the disorder of glucose and lipid metabolism. The change in blood lipid ratio is more pronounced than that of single lipid indicator and is closely related to CysC and Hcy. Dynamic monitoring of Thyroid Stimulating Hormone (TSH), blood lipid ratio, CysC and Hcy is of great value in the diagnosis of thyroid dysfunction and the prediction of Cardiovascular Disease (CVD) in concurrent Coronary Heart Disease (CHD) and so on.
Hyperthyroidism, Hypothyroidism, Blood Glucose, Blood Lipid Ratio, Cystain C, Homocysteine
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Rongqin Dai, Zhenjiang Hou, Jingyu Zhang, Hong Fan, Hongsheng Wang, Jianzhang Hou, The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction, Science Journal of Public Health. Vol. 6, No. 2, 2018, pp. 55-60. doi: 10.11648/j.sjph.20180602.14
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