Science Journal of Public Health

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Evaluation of Health Related Quality of Life in Cancer Patients Receiving Chemotherapy

Received: 11 January 2017    Accepted: 18 January 2017    Published: 14 February 2017
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Abstract

Background: Cancer is considered as the second leading cause of death worldwide. Objectives: To evaluate health-related quality of life (HRQOL) among cancer patients receiving chemotherapy and to identify the most important determinants that affect them. Methods: This cross-sectional study included 190 cancer patients who have been received chemotherapy at the day care clinics in Nasser Institute Cancer Center (NICC). To address our subject, we analyzed HRQOL, as measured by the Functional Assessment of Cancer Therapy-General questionnaire (FACT-G), Arabic Version 4, and depicted the complex relations among physical, psychological, social, and cultural factors. Results: From cancer patients (190) [aged from 23 to 81 years (50.63±11.79)] 153 patients (80.53%) were females. FACT-G total score ranged from 21.2 to 87 (63.24±12.74) which is considered relatively poor (the physical and functional domains were more affected). HRQOL of the study group was not affected by gender, employment status, education level, smoking habits or marital status while it was negatively correlated with age, time since diagnosis of cancer, and disease stage. Patients’ HRQOL shown to be affected by the presence of many variables like low-performance status as evaluated by Eastern Cooperative Oncology Group (ECOG) scale, associated comorbidities, exposure to radiotherapy, history of surgery, and absence of menstrual status in female patients. A positive correlation was found between HRQOL and higher body mass index (BMI), and it was observed that the HRQOL of patients with higher perceived financial status was better. Conclusion: The HRQOL of cancer patients tended to be lower than the norms of the healthy people. Preplanned health programs should be designed to support early disease diagnosis, optimizing treatment choices, controlling of associated comorbidities, improving patients’ performance status as well as working on improving health insurance coverage.

DOI 10.11648/j.sjph.s.2017050501.11
Published in Science Journal of Public Health (Volume 5, Issue 5-1, October 2017)

This article belongs to the Special Issue Malnutrition in Developing Countries

Page(s) 1-7
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Cancer, Chemotherapy, Health Related Quality of Life

References
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[4] Priestman T. Cancer Chemotherapy in Clinical Practice. Second edition. Springer. 2012. DOI 10.1007/978-0-85729-727-3.
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[6] Klee MC, King MT, Machin D, Hansen HH. A clinical model for quality of life assessment in cancer patients receiving chemotherapy. Ann Oncol. 2000; 11 (1): 23-30.
[7] Siddiqui F, Kachnic LA, Movsas B. Quality-of-life outcomes in oncology. Hematol Oncol Clin North Am. 2006 Feb; 20 (1): 165–185.
[8] Cella D, Tulsky D, Gray G, Linn E, Bonomi A, Silberman M, Yellen SB, Winicour P, Brannon J. The Functional Assessment of Cancer Therapy Scale: development and validation of the general measure. J Clin Oncol 1993; 11 (3): 570-579.
[9] Cella D, Hernandez L, Bonomi AE, Corona M, Vaquero M, Shiomoto G, Baez L. Spanish language translation and initial validation of the functional assessment of cancer therapy quality of life instrument. Med Care 1998 Sep; 36 (9): 1407-1418
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[13] Wan G, Counte M, Cella D, Hernandez L, McGuire DB, Deasay S, Shiomoto G, Hahn EA. The impact of socio-cultural and clinical factors on health-related quality of life reports among Hispanic and African-American cancer patients. J Outcome Meas. 1999; 3 (3): 200–215.
[14] kholoud A, Abdul-Monim B, Mohammed S, Mohammed A. Impact of Radiotherapy Treatment on Jordanian Cancer Patients Quality of Life and Fatigue. International Journal of Advanced Nursing Studies. 2014; 3 (1): 6-12.
[15] Mei F, Amber D, Guth J, Charles M. Cleland, Caitlin E. Ryan, Kristen R. Weaver, Jeanna M. Qiu, Robin Kleinman, Joan Scagliola, Joseph J. Palamar, and Gail D’Eramo Melkus. Comorbidities and Quality of Life among Breast Cancer Survivors: A Prospective Study J Pers Med. 2015 Sep; 5 (3): 229–242.
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Author Information
  • Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt

  • Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt

  • Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt

  • Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt

  • Department of Community Medicine, Faculty of Medicine, Benha University, Benha, Egypt

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    Abdelrahim Saad Shoulah, Mahmoud Ali Saleh, Shereen Mohamed Abdelwahab, Mona Ahmad Elawady, Eman Fadel Elsheikh. (2017). Evaluation of Health Related Quality of Life in Cancer Patients Receiving Chemotherapy. Science Journal of Public Health, 5(5-1), 1-7. https://doi.org/10.11648/j.sjph.s.2017050501.11

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    ACS Style

    Abdelrahim Saad Shoulah; Mahmoud Ali Saleh; Shereen Mohamed Abdelwahab; Mona Ahmad Elawady; Eman Fadel Elsheikh. Evaluation of Health Related Quality of Life in Cancer Patients Receiving Chemotherapy. Sci. J. Public Health 2017, 5(5-1), 1-7. doi: 10.11648/j.sjph.s.2017050501.11

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    AMA Style

    Abdelrahim Saad Shoulah, Mahmoud Ali Saleh, Shereen Mohamed Abdelwahab, Mona Ahmad Elawady, Eman Fadel Elsheikh. Evaluation of Health Related Quality of Life in Cancer Patients Receiving Chemotherapy. Sci J Public Health. 2017;5(5-1):1-7. doi: 10.11648/j.sjph.s.2017050501.11

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  • @article{10.11648/j.sjph.s.2017050501.11,
      author = {Abdelrahim Saad Shoulah and Mahmoud Ali Saleh and Shereen Mohamed Abdelwahab and Mona Ahmad Elawady and Eman Fadel Elsheikh},
      title = {Evaluation of Health Related Quality of Life in Cancer Patients Receiving Chemotherapy},
      journal = {Science Journal of Public Health},
      volume = {5},
      number = {5-1},
      pages = {1-7},
      doi = {10.11648/j.sjph.s.2017050501.11},
      url = {https://doi.org/10.11648/j.sjph.s.2017050501.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.sjph.s.2017050501.11},
      abstract = {Background: Cancer is considered as the second leading cause of death worldwide. Objectives: To evaluate health-related quality of life (HRQOL) among cancer patients receiving chemotherapy and to identify the most important determinants that affect them. Methods: This cross-sectional study included 190 cancer patients who have been received chemotherapy at the day care clinics in Nasser Institute Cancer Center (NICC). To address our subject, we analyzed HRQOL, as measured by the Functional Assessment of Cancer Therapy-General questionnaire (FACT-G), Arabic Version 4, and depicted the complex relations among physical, psychological, social, and cultural factors. Results: From cancer patients (190) [aged from 23 to 81 years (50.63±11.79)] 153 patients (80.53%) were females. FACT-G total score ranged from 21.2 to 87 (63.24±12.74) which is considered relatively poor (the physical and functional domains were more affected). HRQOL of the study group was not affected by gender, employment status, education level, smoking habits or marital status while it was negatively correlated with age, time since diagnosis of cancer, and disease stage. Patients’ HRQOL shown to be affected by the presence of many variables like low-performance status as evaluated by Eastern Cooperative Oncology Group (ECOG) scale, associated comorbidities, exposure to radiotherapy, history of surgery, and absence of menstrual status in female patients. A positive correlation was found between HRQOL and higher body mass index (BMI), and it was observed that the HRQOL of patients with higher perceived financial status was better. Conclusion: The HRQOL of cancer patients tended to be lower than the norms of the healthy people. Preplanned health programs should be designed to support early disease diagnosis, optimizing treatment choices, controlling of associated comorbidities, improving patients’ performance status as well as working on improving health insurance coverage.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Evaluation of Health Related Quality of Life in Cancer Patients Receiving Chemotherapy
    AU  - Abdelrahim Saad Shoulah
    AU  - Mahmoud Ali Saleh
    AU  - Shereen Mohamed Abdelwahab
    AU  - Mona Ahmad Elawady
    AU  - Eman Fadel Elsheikh
    Y1  - 2017/02/14
    PY  - 2017
    N1  - https://doi.org/10.11648/j.sjph.s.2017050501.11
    DO  - 10.11648/j.sjph.s.2017050501.11
    T2  - Science Journal of Public Health
    JF  - Science Journal of Public Health
    JO  - Science Journal of Public Health
    SP  - 1
    EP  - 7
    PB  - Science Publishing Group
    SN  - 2328-7950
    UR  - https://doi.org/10.11648/j.sjph.s.2017050501.11
    AB  - Background: Cancer is considered as the second leading cause of death worldwide. Objectives: To evaluate health-related quality of life (HRQOL) among cancer patients receiving chemotherapy and to identify the most important determinants that affect them. Methods: This cross-sectional study included 190 cancer patients who have been received chemotherapy at the day care clinics in Nasser Institute Cancer Center (NICC). To address our subject, we analyzed HRQOL, as measured by the Functional Assessment of Cancer Therapy-General questionnaire (FACT-G), Arabic Version 4, and depicted the complex relations among physical, psychological, social, and cultural factors. Results: From cancer patients (190) [aged from 23 to 81 years (50.63±11.79)] 153 patients (80.53%) were females. FACT-G total score ranged from 21.2 to 87 (63.24±12.74) which is considered relatively poor (the physical and functional domains were more affected). HRQOL of the study group was not affected by gender, employment status, education level, smoking habits or marital status while it was negatively correlated with age, time since diagnosis of cancer, and disease stage. Patients’ HRQOL shown to be affected by the presence of many variables like low-performance status as evaluated by Eastern Cooperative Oncology Group (ECOG) scale, associated comorbidities, exposure to radiotherapy, history of surgery, and absence of menstrual status in female patients. A positive correlation was found between HRQOL and higher body mass index (BMI), and it was observed that the HRQOL of patients with higher perceived financial status was better. Conclusion: The HRQOL of cancer patients tended to be lower than the norms of the healthy people. Preplanned health programs should be designed to support early disease diagnosis, optimizing treatment choices, controlling of associated comorbidities, improving patients’ performance status as well as working on improving health insurance coverage.
    VL  - 5
    IS  - 5-1
    ER  - 

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