Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India
American Journal of Internal Medicine
Volume 2, Issue 1, January 2014, Pages: 6-9
Received: Dec. 29, 2013; Published: Feb. 20, 2014
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Authors
Nazish Fatima, Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Abida Malik, Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Parvez Anwar Khan, Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Sana Ali, Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Haris Manzoor Khan, Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
Nabeela , Immunology section, Dept of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
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Abstract
Background:- Syphilis generally considered to be a sexually transmitted disease, can also be transmitted in utero, and rarely by blood transfusion or non-sexual contact and is characterized by episodes of active disease, interrupted by latency. Congenital syphilis poses a significant challenge especially because infants may be still born, asymptomatic or present with a variable clinical picture at birth. Syphilis has been implicated in increasing susceptibility to HIV infection. We under took this study to determine the seroprevalence of syphilis in a tertiary care setting of Northern India and to identify an association with HIV-infection. Material & Method: - Of the total 19860 samples received during 5 years, VDRL was performed on 19860 samples and TPHA on 65 samples. Results: - 65 (0.33%) were found to be positive by VDRL. The patient’s positive for syphilis included 23 pregnant females (0.15% of the ANC samples received), 14(21.5%) HIV positive patients, 24 were from STD clinic (2.3% of the samples received from STD clinic). Conclusions: - The strong association between syphilis and HIV seroprevelence in this study suggests that acceleration of direct linkages between STI testing and HIV counseling and testing will be useful in enhancing the control of STI and HIV in India.
Keywords
Syphilis, VDRL, TPHA, HIV, ANC
To cite this article
Nazish Fatima, Abida Malik, Parvez Anwar Khan, Sana Ali, Haris Manzoor Khan, Nabeela , Sero Prevalence of Syphilis Infection among Patients Attending Antenatal Care & Sexually Transmitted Disease (STD) Clinics: Observations from a Tertiary Care Hospital of Northern India, American Journal of Internal Medicine. Vol. 2, No. 1, 2014, pp. 6-9. doi: 10.11648/j.ajim.20140201.12
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