Pattern of Acute Arthritis in Seventeen Patients with Sarcoidosis
American Journal of Internal Medicine
Volume 4, Issue 6, November 2016, Pages: 148-150
Received: Nov. 27, 2016; Accepted: Dec. 14, 2016; Published: Feb. 2, 2017
Views 2050      Downloads 66
Authors
Hosseinian Amiri "A"., Department of Rheumatology, Imam Khomeini Hospital, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Aliyali "M"., Department of Pulmonology and Intensive Care, Imam Khomeini Hospital, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Abedi "S"., Department of Pulmonology and Intensive Care, Imam Khomeini Hospital, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
sharifpour "A"., Department of Pulmonology and Intensive Care, Imam Khomeini Hospital, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Article Tools
Follow on us
Abstract
Background: Sarcoidosis is a multisystemic disease that most commonly affected organ is lung but other organs such as the liver, skin, eye and musculoskeletal system can be affected (1). The most common rheumatologic findings in sarcoid patients are arthritis that can be acute or chronic but acute form is most common (14). Aim: The aim of this retrospective study was analysis of acute inflammation of joints in 17 patients with sarcoidosis during 2 years from January 2010 to December 2012. Subjects and Methods: This is a retrospective study of sarcoidosis patients with acute onset inflammation in joints during two years from January 2010 to December 2012 that refers to rheumatologic clinic of Mazandaran University of medical sciences. Data were analyzed using the SPSS version 20. Variables analyzed include age, sex, presence of arthritis/periarthritis, the number of involved joints, symmetricity of involvement and kind of arthritis as inflammatory, non inflammatory or septic. Results: At these study 17 sarcoidosis patients with acute onset of joint inflammation refers to our rheumatologic clinic. All of patients were adults between 18 to 52 years old with median age of 36.8 years old. Six patients (35%) were male and eleven patients (65%) were female. Arthritis occurs in 13 patients (76%) and periarthrtis in 10 patients (58%). At 6 patients (35%), arthritis and periarthritis occurs simultaneously. The most commonly involved join was ankle in 10(58%) cases. Another involved joints were knee, wrist and MCPs in 2 patients (12%) for each ones. Mid foot involvements occurs in 3(18%) and MCPs in one (6%) patient. In seven (41%) patients, arthritis were monoarthicular andat anotherseven (41%) of patients arthritis were oligoathicular. Only in 3 (13%) cases, arthritis were polyarthicular. All of arthritis were inflammatory and only in one case septic arthritis occurs. In 9(53%) of patients, arthritis were symmetric and in 8(47%) of cases were asymmetric. Conclusion: Inflammation of joints including arthritis and periarthrtis are important findings in acute sarcoidosis and must be considered in these patients. Lower extremity joint arthritis especially in ankles and in symmetric fashion are common rheumatologic complications of this disease.
Keywords
Sarcoidosis, Arthritis, Periarthritis
To cite this article
Hosseinian Amiri "A"., Aliyali "M"., Abedi "S"., sharifpour "A"., Pattern of Acute Arthritis in Seventeen Patients with Sarcoidosis, American Journal of Internal Medicine. Vol. 4, No. 6, 2016, pp. 148-150. doi: 10.11648/j.ajim.20160406.19
Copyright
Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
Hunninghake GW, Costabel U, Ando M, et al. ATS/ERS/WASOG statement on sarcoidosis. American Thoracic Society/European Respiratory Society/World Association of Sarcoidosis and other Granulomatous Disorders. Sarcoidosis Vas Diffuse Lung Dis 1999; 16:149–173.
[2]
Moller DR. Rare manifestations of sarcoidosis. In: Drent M, Costabel U, eds. Sarcoidosis. Vol 10. Wakefi eld, UK: European Respiratory Society Journals, Ltd.; 2005:233–250.
[3]
Kitaichi M. Prevalence of sarcoidosis around the world. Sarcoidosis Vas Diffuse Lung Disease 1998; 15:16–18.
[4]
Siltzbach LE, James DG, Neville E, et al. Course and prognosis of sarcoidosis around the world. Am J Med1974; 57:847–852.
[5]
Pietinalho A, Hiraga Y, Hosoda Y, Lofroos AB, Yamaguchi M, Selroos O. The frequency of sarcoidosis inFinland and Hokkaido, Japan. A comparative epidemiological study. Sarcoidosis 1995; 12:61–67.
[6]
Gran JT, Bohmer E. Acute sarcoid arthritis: a favourable outcome? A retrospective survey of 49 patients withreview of the literature. Scand J Rheumatol 1996; 25:70–73.
[7]
Kaplan H. Sarcoid arthritis. A review. Arch Intern Med 1963; 112:924–935.
[8]
Wilcox A, Bharadwaj P, Sharma OP. Bone sarcoidosis. Curr Opin Rheumatol 2000; 12:321–330.
[9]
Sharma OP: Sarcoidosis around the world, Clin Chest Med 29:357–363, vii, 2008.
[10]
American Thoracic Society: Statement on sarcoidosis: joint statement of the American Thoracic Society (ATS), the EuropeanRespiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999, AmJ Respir Crit Care Med 160:736–755, 1999.
[11]
Sweiss NJ, Patterson K, Sawaqed R, et al: Rheumatologic manifestations of sarcoidosis, Semin Respir Crit Care Med 31:463–473, 2010.
[12]
GENDEL BR, YOUNG JM, GREINER DJ. Sarcoidosis; a review with twenty-four additional cases. Am J Med 1952; 12:205.
[13]
Siltzbach LE, Duberstein JL. Arthritis in sarcoidosis. Clin Orthop Relat Res 1968; 57:31.
[14]
Visser H, Vos K, Zanelli E, et al: Sarcoid arthritis: clinical characteristics, diagnostic aspects, and risk factors, Ann Rheum Dis 61:499–504, 2002.
[15]
Glennås A, Kvien TK, Melby K, et al. Acute sarcoid arthritis: occurrence, seasonal onset, clinical features and outcome. Br J Rheumatol 1995; 34:45.
ADDRESS
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
U.S.A.
Tel: (001)347-983-5186