Hypereosinophilic Syndrome - A Case with Churg Strauss Vasculitis
American Journal of Internal Medicine
Volume 5, Issue 5, September 2017, Pages: 83-85
Received: Jan. 31, 2017; Accepted: Feb. 21, 2017; Published: Oct. 23, 2017
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Authors
Blerina Dhamo, Internal and Emergency Medicine Service, Hygeia Hospital, Tirana, Albania
Arben Pilaca, Internal and Emergency Medicine Service, Hygeia Hospital, Tirana, Albania
Gentian Vyshka, Faculty of Medicine, University of Medicine, Tirana, Albania
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Abstract
The hypereosinophilic syndromes represent a group of disorders marked by the sustained overproduction of eosinophils, with eosinophilic infiltration of tissues and mediator release, leading to multiple organic damages. Churg-Strauss syndrome is a rare disorder characterized by systemic small vessel vasculitis, extra vascular granulomas and hypereosinophilia, characteristically occurring in people with background late-onset asthma and allergic rhinitis. Its annual incidence is between 0 and 4 per million of population. The authors present the case of a 72 year old Caucasian female patient, admitted at the Hygeia Hospital Tirana due to a hypereosinophilic syndrome. The thorax CT scan verified bilateral pseudo nodular pulmonary infiltrates; the head MRI showed vascular bilateral lesions in periventricular white matter and centrum semiovale, right internal capsule and left caudate nucleus, and the nerve conduction study (NCS) revealed a distal mixed polyneuropathy. A fibro-gastroscopy with biopsy suggested an atrophic gastritis. The patient underwent a course of treatment with intravenous methylprednisolone, tapered thereafter to oral prednisone together with cyclophosphamide, with a prompt improvement of the clinical picture.
Keywords
Hypereosinophilia, Churg-Strauss Syndrome, Vasculitis, Systemic Changes
To cite this article
Blerina Dhamo, Arben Pilaca, Gentian Vyshka, Hypereosinophilic Syndrome - A Case with Churg Strauss Vasculitis, American Journal of Internal Medicine. Vol. 5, No. 5, 2017, pp. 83-85. doi: 10.11648/j.ajim.20170505.14
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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