Secondary Mesenteric Panniculitis as a Paraneoplastic Syndrome: An Updated Review
American Journal of Internal Medicine
Volume 7, Issue 6, November 2019, Pages: 141-146
Received: Aug. 12, 2019;
Accepted: Sep. 6, 2019;
Published: Oct. 24, 2019
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Mónica García-Fernández, Faculty of Medicine, Miguel Hernández University, Elche, Spain
María Dolores Jover-Ríos, Department of Internal Medicine, Hospital La Vega Baja of Orihuela, Alicante, Spain
Pedro Esteve-Atiénzar, Department of Internal Medicine, University Hospital of San Juan, Alicante, Spain
Juan Méndez-Mora, Department of English, Marist Brothers High School, Alicante, Spain
Alex Méndez-Jover, Department of English, Marist Brothers High School, Alicante, Spain
Sonia Cascant-Pérez, Primary Medicine, Hospital Francesc Borgia of Gandía, Valencia, Spain
Francisco Caparrós-Hernández, Department of English, Marist Brothers High School, Alicante, Spain
Carmen Seguí-Pérez, Department of English, Marist Brothers High School, Alicante, Spain
Marc Seguí-Pérez, Department of English, Marist Brothers High School, Alicante, Spain
Lidia Ramírez-Utrero, Primary Medicine, University Hospital of San Juan, Alicante, Spain
Carles García-Cervera, Department of Internal Medicine, University Hospital of San Juan, Alicante, Spain
Juan Manuel Núñez-Cruz, Department of Internal Medicine, University Hospital of San Juan, Alicante, Spain
David Bonet-Tur, Department of Internal Medicine, University Hospital of San Juan, Alicante, Spain
Sara Bañón-Escandell, Department of Internal Medicine, University Hospital of San Juan, Alicante, Spain
Pablo Roig-Rico, Department of Internal Medicine, University Hospital of San Juan, Alicante, Spain; Department of Clinical Medicine, Miguel Hernández University, Elche, Spain
Jorge Peris-García, Department of Internal Medicine, University Hospital of San Juan, Alicante, Spain; Department of Clinical Medicine, Miguel Hernández University, Elche, Spain
Asunción Pérez-Fullana, Department of English, Marist Brothers High School, Alicante, Spain
José Miguel Seguí-Ripoll, Department of Internal Medicine, University Hospital of San Juan, Alicante, Spain; Department of Clinical Medicine, Miguel Hernández University, Elche, Spain
In response to the case of a patient with mesenteric panniculitis (MP) and proliferative disease, we reviewed the literature on their possible association and associations with other neoplasms. MP is a non-specific chronic inflammation of the mesenteric fat, with low prevalence and unknown etiology; patients may be asymptomatic or present predominantly gastrointestinal complaints. The disease can be either primary or secondary to other pathologies, including neoplastic ones. Diagnosis is made via computed tomography (CT) and confirmed by biopsy. Currently, there is no established treatment for MP. The literature contains series of variable sample sizes, case reports, reviews of other published studies, and some series after a 5-year follow-up. Papers tend to be relatively consistent when it comes to prevalence data and clinical manifestations. However, there is still controversy regarding the role that secondary MP could play in a paraneoplastic picture. From the diagnostic point of view, the incorporation and use of positron emission tomography (PET), together with CT, has been helpful for the approach and the diagnostic focus in this field. Nevertheless, its usage and the discrimination cut point between inflammatory pathology and tumor pathology (maximum standard uptake value: SUVmax) are not clearly defined in neoplastic cases.
María Dolores Jover-Ríos,
Juan Manuel Núñez-Cruz,
José Miguel Seguí-Ripoll,
Secondary Mesenteric Panniculitis as a Paraneoplastic Syndrome: An Updated Review, American Journal of Internal Medicine.
Vol. 7, No. 6,
2019, pp. 141-146.
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