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Diabetic Foot Ulcer: A Review

Received: 18 December 2014    Accepted: 30 December 2014    Published: 26 February 2015
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Abstract

Diabetic foot problems are common throughout the world, resulting in major medical, social and economic consequences for the patients, their families, and society. Foot ulcers are more likely to be of neuropathic origin, and therefore eminently preventable. People at greatest risk of ulceration can easily be identified by careful clinical examination of the feet: education and frequent follow-up. Infection when complicates a foot ulcer, combination can be limb or life-threatening, and infection is defined clinically, but wound cultures assist in identifying the causative pathogens. Tissue specimens are strongly preferred to wound swabs for wound cultures. Antimicrobial therapy should be guided by culture results, and although such therapy may cure the infection, it does not heal the wound. Alleviation of the mechanical load on ulcers (offloading) should always be a part of treatment. Plantar neuropathic ulcers typically heal in 6 weeks with irremovable casting, because pressure at the ulcer site is mitigated and compliance is enforced. The success of other approaches to offloading similarly depends on the patients’ adherence to the effectiveness of pressure relief.

Published in American Journal of Internal Medicine (Volume 3, Issue 2)
DOI 10.11648/j.ajim.20150302.11
Page(s) 28-49
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Diabetic Foot, India

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    Mohammad Zubair, Abida Malik, Jamal Ahmad. (2015). Diabetic Foot Ulcer: A Review. American Journal of Internal Medicine, 3(2), 28-49. https://doi.org/10.11648/j.ajim.20150302.11

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    ACS Style

    Mohammad Zubair; Abida Malik; Jamal Ahmad. Diabetic Foot Ulcer: A Review. Am. J. Intern. Med. 2015, 3(2), 28-49. doi: 10.11648/j.ajim.20150302.11

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    AMA Style

    Mohammad Zubair, Abida Malik, Jamal Ahmad. Diabetic Foot Ulcer: A Review. Am J Intern Med. 2015;3(2):28-49. doi: 10.11648/j.ajim.20150302.11

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  • @article{10.11648/j.ajim.20150302.11,
      author = {Mohammad Zubair and Abida Malik and Jamal Ahmad},
      title = {Diabetic Foot Ulcer: A Review},
      journal = {American Journal of Internal Medicine},
      volume = {3},
      number = {2},
      pages = {28-49},
      doi = {10.11648/j.ajim.20150302.11},
      url = {https://doi.org/10.11648/j.ajim.20150302.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20150302.11},
      abstract = {Diabetic foot problems are common throughout the world, resulting in major medical, social and economic consequences for the patients, their families, and society. Foot ulcers are more likely to be of neuropathic origin, and therefore eminently preventable. People at greatest risk of ulceration can easily be identified by careful clinical examination of the feet: education and frequent follow-up. Infection when complicates a foot ulcer, combination can be limb or life-threatening, and infection is defined clinically, but wound cultures assist in identifying the causative pathogens. Tissue specimens are strongly preferred to wound swabs for wound cultures. Antimicrobial therapy should be guided by culture results, and although such therapy may cure the infection, it does not heal the wound. Alleviation of the mechanical load on ulcers (offloading) should always be a part of treatment. Plantar neuropathic ulcers typically heal in 6 weeks with irremovable casting, because pressure at the ulcer site is mitigated and compliance is enforced. The success of other approaches to offloading similarly depends on the patients’ adherence to the effectiveness of pressure relief.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Diabetic Foot Ulcer: A Review
    AU  - Mohammad Zubair
    AU  - Abida Malik
    AU  - Jamal Ahmad
    Y1  - 2015/02/26
    PY  - 2015
    N1  - https://doi.org/10.11648/j.ajim.20150302.11
    DO  - 10.11648/j.ajim.20150302.11
    T2  - American Journal of Internal Medicine
    JF  - American Journal of Internal Medicine
    JO  - American Journal of Internal Medicine
    SP  - 28
    EP  - 49
    PB  - Science Publishing Group
    SN  - 2330-4324
    UR  - https://doi.org/10.11648/j.ajim.20150302.11
    AB  - Diabetic foot problems are common throughout the world, resulting in major medical, social and economic consequences for the patients, their families, and society. Foot ulcers are more likely to be of neuropathic origin, and therefore eminently preventable. People at greatest risk of ulceration can easily be identified by careful clinical examination of the feet: education and frequent follow-up. Infection when complicates a foot ulcer, combination can be limb or life-threatening, and infection is defined clinically, but wound cultures assist in identifying the causative pathogens. Tissue specimens are strongly preferred to wound swabs for wound cultures. Antimicrobial therapy should be guided by culture results, and although such therapy may cure the infection, it does not heal the wound. Alleviation of the mechanical load on ulcers (offloading) should always be a part of treatment. Plantar neuropathic ulcers typically heal in 6 weeks with irremovable casting, because pressure at the ulcer site is mitigated and compliance is enforced. The success of other approaches to offloading similarly depends on the patients’ adherence to the effectiveness of pressure relief.
    VL  - 3
    IS  - 2
    ER  - 

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Author Information
  • Rajiv Gandhi Centre for Diabetes and Endocrinology, Faculty of Medicine, Aligarh Muslim University, Aligarh 202002, India

  • Department of Microbiology, Faculty of Medicine, Aligarh Muslim University, Aligarh, India

  • Rajiv Gandhi Centre for Diabetes and Endocrinology, Faculty of Medicine, Aligarh Muslim University, Aligarh 202002, India

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