Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report

Michael Masoomi; Alshaima Al-Shammeri; Esraa Al-Qattan; Haytham Ramzy; Hany A Elrahman; Aisha Al-Qattan; Latifah Al-Kandari; Iman Al-Shammeri

doi:doi:10.11648/j.ajim.20200805.15

Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report

Michael Masoomi, Alshaima Al-Shammeri, Esraa Al-Qattan, Haytham Ramzy, Hany A Elrahman, Aisha Al-Qattan, Latifah Al-Kandari, Iman Al-Shammeri

Published in American Journal of Internal Medicine (Volume 8, Issue 5)

Received: 24 July 2020 Accepted: 10 August 2020 Published: 25 August 2020

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Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the infectious disease COVID-19, was declared a global pandemic in March 2020. The SARS-CoV-2 infection has polymorphic clinical presentations. The real time PCR is the reference diagnostic test; however, it can only detect the presence of virus for a specific window of time and its sensitivity has been reported as low as 60–70%. Case: We report a clinical case for a 28-year-old male patient. His clinical history included known NHL (large B-cell lymphoma) that treated with chemotherapy and autologous bone marrow transplant in 2017. He initially presented with fewer, URTI (upper respiratory infection) and weight loss to have a PET/CT scan for restaging. The follow up PET/CT scan, suggested no worrisome FDG metabolic activity elsewhere to suggest disease recurrence, though, hypermetabolic mediastinal lymph nodes, which were kept with active infectious process and bilateral FDG-avid ground glass attenuation in between the consolidation patches were noted. The follow up RT-PCR post PET/CT scan was proved to be positive. A developed pixelated quantitative map of CT part of the lung using MATLAB showed clearly severity of the lung disease that strongly suggested COVID-19 lung in association with the positive RT-PCR. FDG PET/CT has the potential to add value to the challenges of diagnosing complications caused by viruses such as COVID-19.

Published in	American Journal of Internal Medicine (Volume 8, Issue 5)
DOI	10.11648/j.ajim.20200805.15
Page(s)	221-225
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

PET/CT, MATLAB, COVID-19, Oncology Patient

References

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APA Style

Michael Masoomi, Alshaima Al-Shammeri, Esraa Al-Qattan, Haytham Ramzy, Hany A Elrahman, et al. (2020). Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report. American Journal of Internal Medicine, 8(5), 221-225. https://doi.org/10.11648/j.ajim.20200805.15

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ACS Style

Michael Masoomi; Alshaima Al-Shammeri; Esraa Al-Qattan; Haytham Ramzy; Hany A Elrahman, et al. Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report. Am. J. Intern. Med. 2020, 8(5), 221-225. doi: 10.11648/j.ajim.20200805.15

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AMA Style

Michael Masoomi, Alshaima Al-Shammeri, Esraa Al-Qattan, Haytham Ramzy, Hany A Elrahman, et al. Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report. Am J Intern Med. 2020;8(5):221-225. doi: 10.11648/j.ajim.20200805.15

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@article{10.11648/j.ajim.20200805.15,
  author = {Michael Masoomi and Alshaima Al-Shammeri and Esraa Al-Qattan and Haytham Ramzy and Hany A Elrahman and Aisha Al-Qattan and Latifah Al-Kandari and Iman Al-Shammeri},
  title = {Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report},
  journal = {American Journal of Internal Medicine},
  volume = {8},
  number = {5},
  pages = {221-225},
  doi = {10.11648/j.ajim.20200805.15},
  url = {https://doi.org/10.11648/j.ajim.20200805.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20200805.15},
  abstract = {The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the infectious disease COVID-19, was declared a global pandemic in March 2020. The SARS-CoV-2 infection has polymorphic clinical presentations. The real time PCR is the reference diagnostic test; however, it can only detect the presence of virus for a specific window of time and its sensitivity has been reported as low as 60–70%. Case: We report a clinical case for a 28-year-old male patient. His clinical history included known NHL (large B-cell lymphoma) that treated with chemotherapy and autologous bone marrow transplant in 2017. He initially presented with fewer, URTI (upper respiratory infection) and weight loss to have a PET/CT scan for restaging. The follow up PET/CT scan, suggested no worrisome FDG metabolic activity elsewhere to suggest disease recurrence, though, hypermetabolic mediastinal lymph nodes, which were kept with active infectious process and bilateral FDG-avid ground glass attenuation in between the consolidation patches were noted. The follow up RT-PCR post PET/CT scan was proved to be positive. A developed pixelated quantitative map of CT part of the lung using MATLAB showed clearly severity of the lung disease that strongly suggested COVID-19 lung in association with the positive RT-PCR. FDG PET/CT has the potential to add value to the challenges of diagnosing complications caused by viruses such as COVID-19.},
 year = {2020}
}

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TY  - JOUR
T1  - Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report
AU  - Michael Masoomi
AU  - Alshaima Al-Shammeri
AU  - Esraa Al-Qattan
AU  - Haytham Ramzy
AU  - Hany A Elrahman
AU  - Aisha Al-Qattan
AU  - Latifah Al-Kandari
AU  - Iman Al-Shammeri
Y1  - 2020/08/25
PY  - 2020
N1  - https://doi.org/10.11648/j.ajim.20200805.15
DO  - 10.11648/j.ajim.20200805.15
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 221
EP  - 225
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20200805.15
AB  - The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the infectious disease COVID-19, was declared a global pandemic in March 2020. The SARS-CoV-2 infection has polymorphic clinical presentations. The real time PCR is the reference diagnostic test; however, it can only detect the presence of virus for a specific window of time and its sensitivity has been reported as low as 60–70%. Case: We report a clinical case for a 28-year-old male patient. His clinical history included known NHL (large B-cell lymphoma) that treated with chemotherapy and autologous bone marrow transplant in 2017. He initially presented with fewer, URTI (upper respiratory infection) and weight loss to have a PET/CT scan for restaging. The follow up PET/CT scan, suggested no worrisome FDG metabolic activity elsewhere to suggest disease recurrence, though, hypermetabolic mediastinal lymph nodes, which were kept with active infectious process and bilateral FDG-avid ground glass attenuation in between the consolidation patches were noted. The follow up RT-PCR post PET/CT scan was proved to be positive. A developed pixelated quantitative map of CT part of the lung using MATLAB showed clearly severity of the lung disease that strongly suggested COVID-19 lung in association with the positive RT-PCR. FDG PET/CT has the potential to add value to the challenges of diagnosing complications caused by viruses such as COVID-19.
VL  - 8
IS  - 5
ER  -

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Author Information

Michael Masoomi

Nuclear Medicine and Molecular Imaging Section, Department of Medical Imaging, ADAN Hospital, Ministry of Health, Hadiya, Kuwait
Alshaima Al-Shammeri

Nuclear Medicine and Molecular Imaging Section, Department of Medical Imaging, ADAN Hospital, Ministry of Health, Hadiya, Kuwait
Esraa Al-Qattan

Nuclear Medicine and Molecular Imaging Section, Department of Medical Imaging, ADAN Hospital, Ministry of Health, Hadiya, Kuwait
Haytham Ramzy

Radiology Section, Department of Medical Imaging, ADAN Hospital, Ministry of Health, Hadiya, Kuwait
Hany A Elrahman

Nuclear Medicine and Molecular Imaging Section, Department of Medical Imaging, ADAN Hospital, Ministry of Health, Hadiya, Kuwait
Aisha Al-Qattan

Nuclear Medicine and Molecular Imaging Section, Department of Medical Imaging, ADAN Hospital, Ministry of Health, Hadiya, Kuwait
Latifah Al-Kandari

Radiology Section, Department of Medical Imaging, ADAN Hospital, Ministry of Health, Hadiya, Kuwait
Iman Al-Shammeri

Nuclear Medicine and Molecular Imaging Section, Department of Medical Imaging, ADAN Hospital, Ministry of Health, Hadiya, Kuwait

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APA Style

Michael Masoomi, Alshaima Al-Shammeri, Esraa Al-Qattan, Haytham Ramzy, Hany A Elrahman, et al. (2020). Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report. American Journal of Internal Medicine, 8(5), 221-225. https://doi.org/10.11648/j.ajim.20200805.15

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ACS Style

Michael Masoomi; Alshaima Al-Shammeri; Esraa Al-Qattan; Haytham Ramzy; Hany A Elrahman, et al. Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report. Am. J. Intern. Med. 2020, 8(5), 221-225. doi: 10.11648/j.ajim.20200805.15

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AMA Style

Michael Masoomi, Alshaima Al-Shammeri, Esraa Al-Qattan, Haytham Ramzy, Hany A Elrahman, et al. Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report. Am J Intern Med. 2020;8(5):221-225. doi: 10.11648/j.ajim.20200805.15

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@article{10.11648/j.ajim.20200805.15,
  author = {Michael Masoomi and Alshaima Al-Shammeri and Esraa Al-Qattan and Haytham Ramzy and Hany A Elrahman and Aisha Al-Qattan and Latifah Al-Kandari and Iman Al-Shammeri},
  title = {Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report},
  journal = {American Journal of Internal Medicine},
  volume = {8},
  number = {5},
  pages = {221-225},
  doi = {10.11648/j.ajim.20200805.15},
  url = {https://doi.org/10.11648/j.ajim.20200805.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20200805.15},
  abstract = {The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the infectious disease COVID-19, was declared a global pandemic in March 2020. The SARS-CoV-2 infection has polymorphic clinical presentations. The real time PCR is the reference diagnostic test; however, it can only detect the presence of virus for a specific window of time and its sensitivity has been reported as low as 60–70%. Case: We report a clinical case for a 28-year-old male patient. His clinical history included known NHL (large B-cell lymphoma) that treated with chemotherapy and autologous bone marrow transplant in 2017. He initially presented with fewer, URTI (upper respiratory infection) and weight loss to have a PET/CT scan for restaging. The follow up PET/CT scan, suggested no worrisome FDG metabolic activity elsewhere to suggest disease recurrence, though, hypermetabolic mediastinal lymph nodes, which were kept with active infectious process and bilateral FDG-avid ground glass attenuation in between the consolidation patches were noted. The follow up RT-PCR post PET/CT scan was proved to be positive. A developed pixelated quantitative map of CT part of the lung using MATLAB showed clearly severity of the lung disease that strongly suggested COVID-19 lung in association with the positive RT-PCR. FDG PET/CT has the potential to add value to the challenges of diagnosing complications caused by viruses such as COVID-19.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Value of PET/CT and MATLAB in Detection of COVID-19 in an Oncology Patient - Case Report
AU  - Michael Masoomi
AU  - Alshaima Al-Shammeri
AU  - Esraa Al-Qattan
AU  - Haytham Ramzy
AU  - Hany A Elrahman
AU  - Aisha Al-Qattan
AU  - Latifah Al-Kandari
AU  - Iman Al-Shammeri
Y1  - 2020/08/25
PY  - 2020
N1  - https://doi.org/10.11648/j.ajim.20200805.15
DO  - 10.11648/j.ajim.20200805.15
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 221
EP  - 225
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20200805.15
AB  - The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the infectious disease COVID-19, was declared a global pandemic in March 2020. The SARS-CoV-2 infection has polymorphic clinical presentations. The real time PCR is the reference diagnostic test; however, it can only detect the presence of virus for a specific window of time and its sensitivity has been reported as low as 60–70%. Case: We report a clinical case for a 28-year-old male patient. His clinical history included known NHL (large B-cell lymphoma) that treated with chemotherapy and autologous bone marrow transplant in 2017. He initially presented with fewer, URTI (upper respiratory infection) and weight loss to have a PET/CT scan for restaging. The follow up PET/CT scan, suggested no worrisome FDG metabolic activity elsewhere to suggest disease recurrence, though, hypermetabolic mediastinal lymph nodes, which were kept with active infectious process and bilateral FDG-avid ground glass attenuation in between the consolidation patches were noted. The follow up RT-PCR post PET/CT scan was proved to be positive. A developed pixelated quantitative map of CT part of the lung using MATLAB showed clearly severity of the lung disease that strongly suggested COVID-19 lung in association with the positive RT-PCR. FDG PET/CT has the potential to add value to the challenges of diagnosing complications caused by viruses such as COVID-19.
VL  - 8
IS  - 5
ER  -

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