Journal of Surgery
Volume 2, Issue 6, December 2014, Pages: 88-92
Received: Sep. 16, 2014;
Accepted: Sep. 29, 2014;
Published: Dec. 16, 2014
Views 3021 Downloads 172
Safak Ozturk, Tepecik Teaching and Research Hospital, Department of General Surgery, Izmir, Turkey
Ozhan Cetindag, Tepecik Teaching and Research Hospital, Department of General Surgery, Izmir, Turkey
Mutlu Unver, Tepecik Teaching and Research Hospital, Department of General Surgery, Izmir, Turkey
Melek Uncel, Tepecik Teaching and Research Hospital, Department of Pathology, Izmir, Turkey
Burcin Kibar Ozturk, Ege University Faculty of Medicine, Department of Radiology, Izmir, Turkey
Eyup Kebabci, Tepecik Teaching and Research Hospital, Department of General Surgery, Izmir, Turkey
Umit Bayol, Tepecik Teaching and Research Hospital, Department of Pathology, Izmir, Turkey
Introduction: Solid primary tumors of mesenteric origin are quite rare among the intraabdominal soft tissue tumors. The most frequent tumors are Gastrointestinal Stromal Tumors (GIST) and smooth muscle tumors. GISTs as the largest group of these tumors are usually seen in the wall of gastrointestinal tract and 25% of them are malignant. They usually occur in adults and there is no sexual predominance. We present a huge intra-abdominal myoma clinically mimicking GIST. Case Report: A 49-years old male was referred to our deparment because of a growing mass and pain in the right lower quadrant. Physical examination revealed a huge mass with 10 cm in diameter in the right lower quadrant. Computed tomography (CT) revealed a mass with 17 cm in diameter which originated from caecum and extented from umblicus to urinary bladder and right colon. The mass was resected en-bloc with right hemicolectomy. The final diagnosis is ‘’Fibromyoma of the mesentery’’. Discussion: They usually arise de novo and are seen in adults. Myofibroma can occur as a solitary form or it can be seen as multiple lesions like generalized form which is described as myofibromatozis. Myofibromas are characteristically circumscribed masses with a nodular or multinodular growth pattern and they usually show a biphasic growth pattern . The behaviour of mesenteric smooth muscle tumours is unpredictable. Because they arise large diameters and they can cause different clinical symptoms like obstruction and abdominal pain. The treatment of mesenteric fibromyoma is complete resection. Large intraabdominal solid masses pose a diagnostic challenge either grossly or microscopically. Histopathologically, huge benign fibromyomas should be kept in mind of differantial diagnosis of GİSTs.
Burcin Kibar Ozturk,
Mesenteric Fibromyoma Mimicking a Colon Tumor: A Diagnostic Dilemma, Journal of Surgery.
Vol. 2, No. 6,
2014, pp. 88-92.
Kalogiannidis I , Stavrakis T, Amplianitis I, Grammenou S, Mavromatidis G, Rousso D. Primary Mesenteric Smooth Muscle Tumor: An Entity with Unpredictable Biologic Behavior. Case Rep Obstet Gynecol. 2013; 2013: 483689.
Kim MJ, Lee SH, Youk EG, Lee S, Choi JH, Cho KJ. Solitary myofibroma of the sigmoid colon: case report and review of the literature. Diagn Pathol. 2013; 8: 90.
Colombo P, Rahal D, Grizzi F, Quagliuolo V, Roncalli M. Localized intra-abdominal fibromatosis of the small bowel mimicking a gastrointestinal stromal tumor: a case report. World J Gastroenterol. 2005; 11(33): 5226-8.
Montagliani L, Duverger V. Desmoid Tumors. Journal de Chirurgie. 2008; 67(11): 20-26.
Singla SL, Rattan KN, Kaushik N. Mesenteric Leiomyoma in infancy. Indian Journal of Pediatrics. 2000; 67(11): 857-858.
Estes WL. X. Myofibroma of the Large Intestine. Ann Surg. 1906; 44(2): 249–260.
Chung EB, Enzinger FM. Infantile myofibromatosis. Cancer. 1981; 8: 1807–1818.
Stout AP. Juvenile fibromatoses. Cancer. 1954; 8: 953–978.
Fletcher CDM, Unni KK, Mertens F. World health organization classifiction of tumors. Pathology and genetics of tumors of soft tissue and bone. Lyon: IARC Press; 2002.
Yannopoulos K, Stout AP. Primary solid tumors of the mesentery. Cancer. 1963; 16: 914-927.
Fasih N, Shanbhogue AKP, Macdonald DB, et al. Leiomyomas beyond the uterus: unusual locations, rare manifestations. Radiographics. 2008; 28(7): 1931-1948.
Tietze L, Günther K, Hörbe A, et al. Benign metastasizing leiomyoma: a cytogenetically balanced but clonal disease. Human Pathology. 2000; 31(1): 126-128.
Wu W, Chen J, Cao X, Yang M, Zhu J, Zhao G. Solitary infantile myofibromatosis in the bones of the upper extremities: Two rare cases and a review of the literature. Oncology Letter. 2013; 6 (5): 1406-1408.