Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis

Heng Fan; Jian-hua Zhu

doi:doi:10.11648/j.js.20170503.14

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Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis

Heng Fan, Jian-hua Zhu

Published in Journal of Surgery (Volume 5, Issue 3)

Received: 6 April 2017 Accepted: 27 April 2017 Published: 22 June 2017

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Abstract

To determine whether using colonic self-expandable metallic stents (SEMS) as a bridge to surgery for patients with colorectal cancer obstruction induced sepsis (CRCOIS) have better health outcomes compared with emergency surgery (ES). The patients with CRCOIS were enrolled from three university hospitals in China and retrospectively divided into SEMS group (n=32) or ES group (n=20). A total of 52 patients met the inclusion criteria. SEMS group had less the incidence of deep vein thrombosis (P<0.01) and number of organ dysfunction (P<0.01) than ES group. Kaplan-Meier curve showed no significant difference is found in term of 360-day overall survival between the two groups (log-rank test, P = 0.12). However, Multivariable analysis showed the pathological stages (OR: 1.26, 95%CI: 0.72-1.63, P<0.01) and number of organ failure (OR: 0.95, 95%CI: 0.71-1.42, P<0.01) are independent risk factors for 360-day overall survival. Therefore, SEMS placement as a bridge to surgery followed by selective surgery is a feasible and safe procedure for patients with CRCOIS, provides significant advantages of prognosis such as reducing the length of hospital stay, and decreasing the incidence of deep venous thrombosis and organ dysfunction.

Published in	Journal of Surgery (Volume 5, Issue 3)
DOI	10.11648/j.js.20170503.14
Page(s)	53-57
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Self-expandable Metallic Stents, Colorectal Cancer Obstruction, Sepsis, Emergency Surgery

References

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APA Style

Heng Fan, Jian-hua Zhu. (2017). Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis. Journal of Surgery, 5(3), 53-57. https://doi.org/10.11648/j.js.20170503.14

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ACS Style

Heng Fan; Jian-hua Zhu. Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis. J. Surg. 2017, 5(3), 53-57. doi: 10.11648/j.js.20170503.14

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AMA Style

Heng Fan, Jian-hua Zhu. Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis. J Surg. 2017;5(3):53-57. doi: 10.11648/j.js.20170503.14

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@article{10.11648/j.js.20170503.14,
  author = {Heng Fan and Jian-hua Zhu},
  title = {Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis},
  journal = {Journal of Surgery},
  volume = {5},
  number = {3},
  pages = {53-57},
  doi = {10.11648/j.js.20170503.14},
  url = {https://doi.org/10.11648/j.js.20170503.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20170503.14},
  abstract = {To determine whether using colonic self-expandable metallic stents (SEMS) as a bridge to surgery for patients with colorectal cancer obstruction induced sepsis (CRCOIS) have better health outcomes compared with emergency surgery (ES). The patients with CRCOIS were enrolled from three university hospitals in China and retrospectively divided into SEMS group (n=32) or ES group (n=20). A total of 52 patients met the inclusion criteria. SEMS group had less the incidence of deep vein thrombosis (P<0.01) and number of organ dysfunction (P<0.01) than ES group. Kaplan-Meier curve showed no significant difference is found in term of 360-day overall survival between the two groups (log-rank test, P = 0.12). However, Multivariable analysis showed the pathological stages (OR: 1.26, 95%CI: 0.72-1.63, P<0.01) and number of organ failure (OR: 0.95, 95%CI: 0.71-1.42, P<0.01) are independent risk factors for 360-day overall survival. Therefore, SEMS placement as a bridge to surgery followed by selective surgery is a feasible and safe procedure for patients with CRCOIS, provides significant advantages of prognosis such as reducing the length of hospital stay, and decreasing the incidence of deep venous thrombosis and organ dysfunction.},
 year = {2017}
}

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TY  - JOUR
T1  - Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis
AU  - Heng Fan
AU  - Jian-hua Zhu
Y1  - 2017/06/22
PY  - 2017
N1  - https://doi.org/10.11648/j.js.20170503.14
DO  - 10.11648/j.js.20170503.14
T2  - Journal of Surgery
JF  - Journal of Surgery
JO  - Journal of Surgery
SP  - 53
EP  - 57
PB  - Science Publishing Group
SN  - 2330-0930
UR  - https://doi.org/10.11648/j.js.20170503.14
AB  - To determine whether using colonic self-expandable metallic stents (SEMS) as a bridge to surgery for patients with colorectal cancer obstruction induced sepsis (CRCOIS) have better health outcomes compared with emergency surgery (ES). The patients with CRCOIS were enrolled from three university hospitals in China and retrospectively divided into SEMS group (n=32) or ES group (n=20). A total of 52 patients met the inclusion criteria. SEMS group had less the incidence of deep vein thrombosis (P<0.01) and number of organ dysfunction (P<0.01) than ES group. Kaplan-Meier curve showed no significant difference is found in term of 360-day overall survival between the two groups (log-rank test, P = 0.12). However, Multivariable analysis showed the pathological stages (OR: 1.26, 95%CI: 0.72-1.63, P<0.01) and number of organ failure (OR: 0.95, 95%CI: 0.71-1.42, P<0.01) are independent risk factors for 360-day overall survival. Therefore, SEMS placement as a bridge to surgery followed by selective surgery is a feasible and safe procedure for patients with CRCOIS, provides significant advantages of prognosis such as reducing the length of hospital stay, and decreasing the incidence of deep venous thrombosis and organ dysfunction.
VL  - 5
IS  - 3
ER  -

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Author Information

Heng Fan

Department of Intensive Care Unit, Ningbo First Hospital, Ningbo, China
Jian-hua Zhu

Department of Intensive Care Unit, Ningbo First Hospital, Ningbo, China

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Plain Text BibTeX RIS

APA Style

Heng Fan, Jian-hua Zhu. (2017). Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis. Journal of Surgery, 5(3), 53-57. https://doi.org/10.11648/j.js.20170503.14

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ACS Style

Heng Fan; Jian-hua Zhu. Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis. J. Surg. 2017, 5(3), 53-57. doi: 10.11648/j.js.20170503.14

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AMA Style

Heng Fan, Jian-hua Zhu. Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis. J Surg. 2017;5(3):53-57. doi: 10.11648/j.js.20170503.14

Copy | Download

@article{10.11648/j.js.20170503.14,
  author = {Heng Fan and Jian-hua Zhu},
  title = {Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis},
  journal = {Journal of Surgery},
  volume = {5},
  number = {3},
  pages = {53-57},
  doi = {10.11648/j.js.20170503.14},
  url = {https://doi.org/10.11648/j.js.20170503.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20170503.14},
  abstract = {To determine whether using colonic self-expandable metallic stents (SEMS) as a bridge to surgery for patients with colorectal cancer obstruction induced sepsis (CRCOIS) have better health outcomes compared with emergency surgery (ES). The patients with CRCOIS were enrolled from three university hospitals in China and retrospectively divided into SEMS group (n=32) or ES group (n=20). A total of 52 patients met the inclusion criteria. SEMS group had less the incidence of deep vein thrombosis (P<0.01) and number of organ dysfunction (P<0.01) than ES group. Kaplan-Meier curve showed no significant difference is found in term of 360-day overall survival between the two groups (log-rank test, P = 0.12). However, Multivariable analysis showed the pathological stages (OR: 1.26, 95%CI: 0.72-1.63, P<0.01) and number of organ failure (OR: 0.95, 95%CI: 0.71-1.42, P<0.01) are independent risk factors for 360-day overall survival. Therefore, SEMS placement as a bridge to surgery followed by selective surgery is a feasible and safe procedure for patients with CRCOIS, provides significant advantages of prognosis such as reducing the length of hospital stay, and decreasing the incidence of deep venous thrombosis and organ dysfunction.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Colonic Self-Expandable Metallic Stents for Patients with Colorectal Cancer Obstruction Induced Sepsis
AU  - Heng Fan
AU  - Jian-hua Zhu
Y1  - 2017/06/22
PY  - 2017
N1  - https://doi.org/10.11648/j.js.20170503.14
DO  - 10.11648/j.js.20170503.14
T2  - Journal of Surgery
JF  - Journal of Surgery
JO  - Journal of Surgery
SP  - 53
EP  - 57
PB  - Science Publishing Group
SN  - 2330-0930
UR  - https://doi.org/10.11648/j.js.20170503.14
AB  - To determine whether using colonic self-expandable metallic stents (SEMS) as a bridge to surgery for patients with colorectal cancer obstruction induced sepsis (CRCOIS) have better health outcomes compared with emergency surgery (ES). The patients with CRCOIS were enrolled from three university hospitals in China and retrospectively divided into SEMS group (n=32) or ES group (n=20). A total of 52 patients met the inclusion criteria. SEMS group had less the incidence of deep vein thrombosis (P<0.01) and number of organ dysfunction (P<0.01) than ES group. Kaplan-Meier curve showed no significant difference is found in term of 360-day overall survival between the two groups (log-rank test, P = 0.12). However, Multivariable analysis showed the pathological stages (OR: 1.26, 95%CI: 0.72-1.63, P<0.01) and number of organ failure (OR: 0.95, 95%CI: 0.71-1.42, P<0.01) are independent risk factors for 360-day overall survival. Therefore, SEMS placement as a bridge to surgery followed by selective surgery is a feasible and safe procedure for patients with CRCOIS, provides significant advantages of prognosis such as reducing the length of hospital stay, and decreasing the incidence of deep venous thrombosis and organ dysfunction.
VL  - 5
IS  - 3
ER  -

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