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Effect of a Seamless Device for Instillation on Bladder Instillation of Drug After Transurethral Resection of Bladder Tumor

Received: 29 March 2020    Accepted: 16 April 2020    Published: 29 April 2020
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Abstract

Objective: We aim to explore the effect of a seamless device for instillation on bladder instillation of drug after transurethral resection of bladder tumor. Methods: There were 24 patients undergoing transurethral resection of bladder tumor in the department of urinary surgery from January 2019 to December 2019, and 150 person-times of bladder instillation of drug in follow-up. We adopted random number table to averagely divide the 150 person-times into experimental group, control group A and control group B. In the experimental group, before bladder instillation of drug, a 50ml injector was used for dissolution and suction of drug. During instillation of drug, we used heparin cap to connect the injector and catheter to make a seamless device for instillation. In the control group A, before instillation, a 50ml injector was also used for dissolution and suction of drug, but at the same time, the syringe nozzle was inserted into the horn-shaped catheter orifice to inject the drug. In the control group B, we used a 50 ml injector for dissolution and suction of drug before instillation and then injected to drug into an aseptic bowel. After that, we used a 50 ml medical irrigator to draw in the liquid in the bowl and inserted the irrigator nozzle into the horn-shaped catheter orifice to inject the liquid. We compared operator’s satisfaction during instillation, drug leakage and time consumption between the three groups. Results: Operator’s satisfaction in the experimental group, control group A and control group B was 100%, 12% and 84% respectively and there was a significant difference in that between the three groups (χ2=57.576, P=0.000). In terms of drug leakage, there was no leakage in the experimental group, and an average of 11.44±2.13 ml of leakage in the control group A and an average of 0.77±1.14 ml of leakage in the control group B. The one-way analysis of variance showed that there was a significant difference in that (F=1041.089, P=0.000). At last, the time consumption in the experimental group was 9.28±1.21min, and the control group A took the longest time 11.58±1.81 min. The one-way analysis of variance showed that there was a significant difference in time consumption between the three groups (F=32.947, P=0.000). Conclusions: the self-designed seamless device for instillation in the bladder instillation of drug for patients who underwent transurethral resection of bladder tumor can not only ensure the dosage of drug, avoid iatrogenic exposure but also reduce time consumption and improve medical staff’s satisfaction. Hence, the seamless device is worth clinical application.

Published in Journal of Surgery (Volume 8, Issue 2)
DOI 10.11648/j.js.20200802.17
Page(s) 76-80
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Seamless Device for Instillation, Post-transurethral Resection of Bladder Tumor, Bladder Instillation of Drug, Effect

References
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[2] Sanchez, A., Wszolek, M. F., Niemierko, A., Clayman, R. H., Drumm, M., & Rodríguez D, et al. (2018). Incidence, clinicopathological risk factors, management and outcomes of nonmuscle invasive recurrence after complete response to trimodality therapy for muscle invasive bladder cancer. Journal of Urology, 199 (2), 407.
[3] Kaufman, D. S., Shipley, W. U., & Feldman, A. S. (2009). Bladder cancer. 374 (9685), 239-249.
[4] Claire L. Vale. (2003). Adjuvant chemotherapy in invasive bladder cancer: a systematic review and meta-analysis of individual patient data. European Urology, 361 (9373), 202-206.
[5] Di̇vri̇k, R. T., Yildirim, Ü. Zorlu, F. & Özen, H. The Effect of Repeat Transurethral Resection on Recurrence and Progression Rates in Patients With T1 Tumors of the Bladder Who Received Intravesical Mitomycin: A Prospective, Randomized Clinical Trial. The Journal of Urology, 175 (5), 1641-1644.
[6] Sfakianos, J. P., Kim, P. H., Hakimi, A. A., & Herr, H. W. (2014). The effect of restaging transurethral resection on recurrence and progression rates in patients with nonmuscle invasive bladder cancer treated with intravesical bacillus calmette-guérin. The Journal of Urology, 191 (2), 341-345.
[7] Ursula Elsässer-Beile, Leiber, C., Wetterauer, U., Patrick Bühler, & Mengs, U. (2005). Adjuvant intravesical treatment with a standardized mistletoe extract to prevent recurrence of superficial urinary bladder cancer. Anticancer research, 25 (6C), 4733-4736.
[8] Yang Shixi, Zhang Xiangzhi. Improvement of Bladder Infusion Chemotherapy and Observation of Its Adverse Reactions. Journal of Yangtze University (Natural Science Edition), 2017, 14 (12): 58-59+62.
[9] Furuse, H., & Ozono, S. (2010). Transurethral resection of the bladder tumour (turbt) for non-muscle invasive bladder cancer: basic skills. International Journal of Urology, 17 (8), 698-699.
[10] Cao, M., Yang, G., Pan, J., Sun, J., & Xue, W. (2015). Repeated transurethral resection for non-muscle invasive bladder cancer. International Journal of Clinical and Experimental Medicine, 8 (1), 1416-1419.
[11] Kyung Seok Han, Jae Young Joung, Kang Su Cho, Ho Kyung Seo, Jinsoo Chung, Won Seo Park, Kang Hyun Lee. (2008). Results of repeated transurethral resection for a second opinion in patients referred for nonmuscle invasive bladder cancer: the referral cancer center experience and review of the literature. Journal of Endourology, 22 (12): 2699-2704.
[12] Li Cuijuan, Li Yan, Huang Qiaoyi. Improvement and Nursing Observation of Bladder Infusion Chemotherapy. Chinese Journal of Clinical Rational Drug Use, 2009, 2 (18): 61-62.
[13] Zhang Ying, Liang Hui, Huang Cuiping, Xu Ting, Gao Lian, Ma Xuexia. Investigation of Occupational Protection Status of Urinary Bladder Infusion Chemotherapy. Journal of Nurses Training, 2019, 34 (15): 1419-1422.
[14] Ding, E., Xu, X., & Jian, X. (2015). Survey of urology nurses on occupation protection from intravesical chemotherapy. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi, 33 (3), 198-200.
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  • APA Style

    Liu Qian, Guo Xiaoxia. (2020). Effect of a Seamless Device for Instillation on Bladder Instillation of Drug After Transurethral Resection of Bladder Tumor. Journal of Surgery, 8(2), 76-80. https://doi.org/10.11648/j.js.20200802.17

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    ACS Style

    Liu Qian; Guo Xiaoxia. Effect of a Seamless Device for Instillation on Bladder Instillation of Drug After Transurethral Resection of Bladder Tumor. J. Surg. 2020, 8(2), 76-80. doi: 10.11648/j.js.20200802.17

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    AMA Style

    Liu Qian, Guo Xiaoxia. Effect of a Seamless Device for Instillation on Bladder Instillation of Drug After Transurethral Resection of Bladder Tumor. J Surg. 2020;8(2):76-80. doi: 10.11648/j.js.20200802.17

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  • @article{10.11648/j.js.20200802.17,
      author = {Liu Qian and Guo Xiaoxia},
      title = {Effect of a Seamless Device for Instillation on Bladder Instillation of Drug After Transurethral Resection of Bladder Tumor},
      journal = {Journal of Surgery},
      volume = {8},
      number = {2},
      pages = {76-80},
      doi = {10.11648/j.js.20200802.17},
      url = {https://doi.org/10.11648/j.js.20200802.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20200802.17},
      abstract = {Objective: We aim to explore the effect of a seamless device for instillation on bladder instillation of drug after transurethral resection of bladder tumor. Methods: There were 24 patients undergoing transurethral resection of bladder tumor in the department of urinary surgery from January 2019 to December 2019, and 150 person-times of bladder instillation of drug in follow-up. We adopted random number table to averagely divide the 150 person-times into experimental group, control group A and control group B. In the experimental group, before bladder instillation of drug, a 50ml injector was used for dissolution and suction of drug. During instillation of drug, we used heparin cap to connect the injector and catheter to make a seamless device for instillation. In the control group A, before instillation, a 50ml injector was also used for dissolution and suction of drug, but at the same time, the syringe nozzle was inserted into the horn-shaped catheter orifice to inject the drug. In the control group B, we used a 50 ml injector for dissolution and suction of drug before instillation and then injected to drug into an aseptic bowel. After that, we used a 50 ml medical irrigator to draw in the liquid in the bowl and inserted the irrigator nozzle into the horn-shaped catheter orifice to inject the liquid. We compared operator’s satisfaction during instillation, drug leakage and time consumption between the three groups. Results: Operator’s satisfaction in the experimental group, control group A and control group B was 100%, 12% and 84% respectively and there was a significant difference in that between the three groups (χ2=57.576, P=0.000). In terms of drug leakage, there was no leakage in the experimental group, and an average of 11.44±2.13 ml of leakage in the control group A and an average of 0.77±1.14 ml of leakage in the control group B. The one-way analysis of variance showed that there was a significant difference in that (F=1041.089, P=0.000). At last, the time consumption in the experimental group was 9.28±1.21min, and the control group A took the longest time 11.58±1.81 min. The one-way analysis of variance showed that there was a significant difference in time consumption between the three groups (F=32.947, P=0.000). Conclusions: the self-designed seamless device for instillation in the bladder instillation of drug for patients who underwent transurethral resection of bladder tumor can not only ensure the dosage of drug, avoid iatrogenic exposure but also reduce time consumption and improve medical staff’s satisfaction. Hence, the seamless device is worth clinical application.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Effect of a Seamless Device for Instillation on Bladder Instillation of Drug After Transurethral Resection of Bladder Tumor
    AU  - Liu Qian
    AU  - Guo Xiaoxia
    Y1  - 2020/04/29
    PY  - 2020
    N1  - https://doi.org/10.11648/j.js.20200802.17
    DO  - 10.11648/j.js.20200802.17
    T2  - Journal of Surgery
    JF  - Journal of Surgery
    JO  - Journal of Surgery
    SP  - 76
    EP  - 80
    PB  - Science Publishing Group
    SN  - 2330-0930
    UR  - https://doi.org/10.11648/j.js.20200802.17
    AB  - Objective: We aim to explore the effect of a seamless device for instillation on bladder instillation of drug after transurethral resection of bladder tumor. Methods: There were 24 patients undergoing transurethral resection of bladder tumor in the department of urinary surgery from January 2019 to December 2019, and 150 person-times of bladder instillation of drug in follow-up. We adopted random number table to averagely divide the 150 person-times into experimental group, control group A and control group B. In the experimental group, before bladder instillation of drug, a 50ml injector was used for dissolution and suction of drug. During instillation of drug, we used heparin cap to connect the injector and catheter to make a seamless device for instillation. In the control group A, before instillation, a 50ml injector was also used for dissolution and suction of drug, but at the same time, the syringe nozzle was inserted into the horn-shaped catheter orifice to inject the drug. In the control group B, we used a 50 ml injector for dissolution and suction of drug before instillation and then injected to drug into an aseptic bowel. After that, we used a 50 ml medical irrigator to draw in the liquid in the bowl and inserted the irrigator nozzle into the horn-shaped catheter orifice to inject the liquid. We compared operator’s satisfaction during instillation, drug leakage and time consumption between the three groups. Results: Operator’s satisfaction in the experimental group, control group A and control group B was 100%, 12% and 84% respectively and there was a significant difference in that between the three groups (χ2=57.576, P=0.000). In terms of drug leakage, there was no leakage in the experimental group, and an average of 11.44±2.13 ml of leakage in the control group A and an average of 0.77±1.14 ml of leakage in the control group B. The one-way analysis of variance showed that there was a significant difference in that (F=1041.089, P=0.000). At last, the time consumption in the experimental group was 9.28±1.21min, and the control group A took the longest time 11.58±1.81 min. The one-way analysis of variance showed that there was a significant difference in time consumption between the three groups (F=32.947, P=0.000). Conclusions: the self-designed seamless device for instillation in the bladder instillation of drug for patients who underwent transurethral resection of bladder tumor can not only ensure the dosage of drug, avoid iatrogenic exposure but also reduce time consumption and improve medical staff’s satisfaction. Hence, the seamless device is worth clinical application.
    VL  - 8
    IS  - 2
    ER  - 

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Author Information
  • Department of Nursing, The First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department of Urology, The First Affiliated Hospital of Jinan University, Guangzhou, China

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