Background: Acute cholecystitis (AC) is the most common complication of gall bladder stones. C-reactive protein (CRP) level is only used as a diagnostic criterion of AC. Because there is the lack of studies demonstrating a better discrimination power of CRP measurement on AC, The aim of this study was evaluate the discriminative power of CRP in AC management and treatment outcome. Patients and methods: The number of patients in this study was 30 patients presented with AC. After clinical examination, Laboratory and radiological investigations and resuscitation within 1st 24h. of admission, all patients treated by laparoscopic cholecystectomy (LC). Results: Out of total participants, 8 patients were males (26.7%) and 22 females (73.3%). There ages ranged from 21 to 66 years with mean ± SD 11.29. Higher levels CRP were found in cases of high grade fever, palpable tender RT. hypochondrial mass and pyocele cases with significant difference was 0.001, 0.001 and 0.005 respectively. Timing of intervention was within 7 days from 1st symptom day ranging 2-7 days with mean 4.37. Total operative time was ranging from 42-180 minutes with mean 109.57. Blood loss ranging from 50-200 cc with mean 95. Total hospital stay ranged from 4-6 days. Conclusion: High levels of CRP with male sex, high grade fever preoperatively, presence of palpable tender RT. hypochondrial mass, high total leucocytic count, cases of pyocele and presence of intra-operative adhesion and timing of intervention are risk factors for difficulty, complications, operative and postoperative out come in patients undergoing laparoscopic cholecystectomy for Acute cholecystitis.
| Published in |
Journal of Surgery (Volume 5, Issue 3-1)
This article belongs to the Special Issue Minimally Invasive and Minimally Access Surgery |
| DOI | 10.11648/j.js.s.2017050301.14 |
| Page(s) | 16-22 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
C-reactive Protein, Risk Factor, Acute Cholecystitis, Complication Laparoscopic Cholecystectomy
| [1] | Strasberg SM. Clinical practice. Acute calculus cholecystitis. N Eng J Med 2008; 358 (26): 2804. |
| [2] | Brook OR, Kane RA, Tyagi G, et al. Lessons learned from quality assurance: errors in the diagnosis of acute cholecystitis on ultrasound and CT. AJR AMJ Roentgenol 2011; 196:597. |
| [3] | Sonjay P, Miltpall D, Marioud A, et al. Clinical outcome of a percutaneous cholecystectomy for acute cholecystitis: a multicentre analysis. HPB (oxford) 2013; 15: 511. |
| [4] | Smith Tj, Manske JG, Mathiason MA, et al. Changing trends and outcomes in the use of percutaneous cholecystostomy tubes for acute cholecystitis. Ann Surg 2013; 257: 1112. |
| [5] | Riall TS, Zhang D, Townsad CN, et al. Failure to perform cholecystectomy for acute cholecystitis in elderly patients is associated with increased morbidity, mortality and costs. J Am CollSurg 2010; 210: 668. |
| [6] | Hirota M, Takada T, Kowarad Y, et al. Diagnostic criteria and severity assessment of acute cholecystitis Tokyo guidelines J Hepato-Biliary pancreatSurg 2007;14:78. |
| [7] | Yokoem, Tokada T, Strasberg SM, et al. TG 2013 diagnostic criteria and severity grading of acute cholecystitis (with videos) J Hepato-Biliary pancreatSurg 2013;20:35. |
| [8] | Aydin C, Altraca G, Rerber I, et al. Prognostic parameters for the prediction of acute gangrenous cholecystitis. J Hepato-Biliary pancreatSurg 2006; 3(2): 155. |
| [9] | WeverskP, wessternen HL, Patijn GA. Laparoscopic cholecystectomy in acute cholecystitis: C-reactive protein level combined with age predicts conversion SurglaproscEndoscprecutan Tech.2013; 23(2): 136. |
| [10] | Mokk W, Reddy R, Wood F, et al. is C-reactive protein a useful adjunct in selecting patients for emergency cholecystectomy by predicting severe gangrenous cholecystitis ? IJS 2014; 12(7): 649. |
| [11] | Asai K, Watanabe M, Kusachi S, et al. Bacteriological analysis of bile in acute cholecystitis according to The Tokyo guidelines. J Hepato-Biliary pancreatSci 201; 19(4): 476. |
| [12] | Esin KG, Bunymin G, Ismail EA, et al. prediction of the grade of acute cholecystitis by plasma level of C-reactive protein. IRC Med 2015, 17(4); 28091. |
| [13] | Shinke G, Nnada T, Hatana H, et al, Feasibility and safety of urgent laparoscopic cholecystectomy for acute cholecystitis after 4 days from symptoms onset. J GastrointestinSurg 2015; 19: 1787. |
| [14] | Teckchandani N, Garg PK, Hadke NS, et al, predictive factors for successful early laparoscopic cholecystectomy in acute cholecystitis a prospective study IJS 2010; 8: 623. |
| [15] | Ohata M, Lwashita Y, Yada K et al, operative timing of laparoscopic cholecystectomy for acute cholecystitis in a Japanese institute J of the Society of laparo Endoscopic Surgeons 2012; 16: 65. |
| [16] | Ambe PE and Kohler L. is the male gender an independent risk factor for complication in patients under going cholecystectomy? IJS 2015, 100: 854. |
| [17] | Bansal AR, Arora V, Dangi A, et al. Evaluation of early versus interval laparoscopic cholecystectomy in acute calculus cholecystitis. Hellenic Journal of Surgery 2015; 87: 224. |
| [18] | Al- Qahtani HH. laparoscopic cholecystectomy within one week from onset of acute cholecystitis: A 6 year experience. Journal of Taibah university Medical sciences 2013; 8: 38. |
| [19] | Farooq T, Buchanan G, Manda V, et al. Is early laparoscopic cholecystectomy safe after the "safe period" Journal of Laparoscopic and Advanced Surgical Technique 2009; 19: 471. |
| [20] | Popkharitov AI. Laparoscopic cholecystectomy for a cute cholecystitis. Langenbeck's Archives of Surgery 2008; 393: 935. |
| [21] | Andrei MB and Michael B. C-reactive protein measurement is not associated with an improved management of acute cholecystitis: a pile for change. JSR 2015; 198: 93. |
APA Style
Hamdy A. Elhady, Taha Ahmed Esmail. (2017). Is C-reactive Protein an Independent Risk Factor for Complication of Laparoscopic Cholecystectomy for Acute Cholecystitis. Journal of Surgery, 5(3-1), 16-22. https://doi.org/10.11648/j.js.s.2017050301.14
ACS Style
Hamdy A. Elhady; Taha Ahmed Esmail. Is C-reactive Protein an Independent Risk Factor for Complication of Laparoscopic Cholecystectomy for Acute Cholecystitis. J. Surg. 2017, 5(3-1), 16-22. doi: 10.11648/j.js.s.2017050301.14
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.js.s.2017050301.14,
author = {Hamdy A. Elhady and Taha Ahmed Esmail},
title = {Is C-reactive Protein an Independent Risk Factor for Complication of Laparoscopic Cholecystectomy for Acute Cholecystitis},
journal = {Journal of Surgery},
volume = {5},
number = {3-1},
pages = {16-22},
doi = {10.11648/j.js.s.2017050301.14},
url = {https://doi.org/10.11648/j.js.s.2017050301.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.s.2017050301.14},
abstract = {Background: Acute cholecystitis (AC) is the most common complication of gall bladder stones. C-reactive protein (CRP) level is only used as a diagnostic criterion of AC. Because there is the lack of studies demonstrating a better discrimination power of CRP measurement on AC, The aim of this study was evaluate the discriminative power of CRP in AC management and treatment outcome. Patients and methods: The number of patients in this study was 30 patients presented with AC. After clinical examination, Laboratory and radiological investigations and resuscitation within 1st 24h. of admission, all patients treated by laparoscopic cholecystectomy (LC). Results: Out of total participants, 8 patients were males (26.7%) and 22 females (73.3%). There ages ranged from 21 to 66 years with mean ± SD 11.29. Higher levels CRP were found in cases of high grade fever, palpable tender RT. hypochondrial mass and pyocele cases with significant difference was 0.001, 0.001 and 0.005 respectively. Timing of intervention was within 7 days from 1st symptom day ranging 2-7 days with mean 4.37. Total operative time was ranging from 42-180 minutes with mean 109.57. Blood loss ranging from 50-200 cc with mean 95. Total hospital stay ranged from 4-6 days. Conclusion: High levels of CRP with male sex, high grade fever preoperatively, presence of palpable tender RT. hypochondrial mass, high total leucocytic count, cases of pyocele and presence of intra-operative adhesion and timing of intervention are risk factors for difficulty, complications, operative and postoperative out come in patients undergoing laparoscopic cholecystectomy for Acute cholecystitis.},
year = {2017}
}
TY - JOUR T1 - Is C-reactive Protein an Independent Risk Factor for Complication of Laparoscopic Cholecystectomy for Acute Cholecystitis AU - Hamdy A. Elhady AU - Taha Ahmed Esmail Y1 - 2017/02/06 PY - 2017 N1 - https://doi.org/10.11648/j.js.s.2017050301.14 DO - 10.11648/j.js.s.2017050301.14 T2 - Journal of Surgery JF - Journal of Surgery JO - Journal of Surgery SP - 16 EP - 22 PB - Science Publishing Group SN - 2330-0930 UR - https://doi.org/10.11648/j.js.s.2017050301.14 AB - Background: Acute cholecystitis (AC) is the most common complication of gall bladder stones. C-reactive protein (CRP) level is only used as a diagnostic criterion of AC. Because there is the lack of studies demonstrating a better discrimination power of CRP measurement on AC, The aim of this study was evaluate the discriminative power of CRP in AC management and treatment outcome. Patients and methods: The number of patients in this study was 30 patients presented with AC. After clinical examination, Laboratory and radiological investigations and resuscitation within 1st 24h. of admission, all patients treated by laparoscopic cholecystectomy (LC). Results: Out of total participants, 8 patients were males (26.7%) and 22 females (73.3%). There ages ranged from 21 to 66 years with mean ± SD 11.29. Higher levels CRP were found in cases of high grade fever, palpable tender RT. hypochondrial mass and pyocele cases with significant difference was 0.001, 0.001 and 0.005 respectively. Timing of intervention was within 7 days from 1st symptom day ranging 2-7 days with mean 4.37. Total operative time was ranging from 42-180 minutes with mean 109.57. Blood loss ranging from 50-200 cc with mean 95. Total hospital stay ranged from 4-6 days. Conclusion: High levels of CRP with male sex, high grade fever preoperatively, presence of palpable tender RT. hypochondrial mass, high total leucocytic count, cases of pyocele and presence of intra-operative adhesion and timing of intervention are risk factors for difficulty, complications, operative and postoperative out come in patients undergoing laparoscopic cholecystectomy for Acute cholecystitis. VL - 5 IS - 3-1 ER -
Information
Email: