Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire

Sekongo Y. M.; Kouamenan S.; Siransy B. L.; Ouattara B.; Konan S.; Dembele B.; Tolo D.A.; Hyda J.; Kabore S.; Konate S.

doi:doi:10.11648/j.ajcem.20130103.14

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Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire

Sekongo Y. M., Kouamenan S., Siransy B. L., Ouattara B., Konan S., Dembele B., Tolo D.A., Hyda J., Kabore S., Konate S.

Published in American Journal of Clinical and Experimental Medicine (Volume 1, Issue 3)

Received: 20 November 2013 Accepted: Published: 10 January 2014

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Abstract

In Ivory Coast, Sickle cell disease is a public health problem. Approximately, there are 98,000 blood donors annually to the national blood transfusion center. Among these, some holders of abnormal hemoglobins are often diagnosed. The objective of this study is to determine the prevalence of abnormal hemoglobins during a mass balance for the integration into an army corps those are asymptomatic blood donors. This prospective and descriptive study took place in a gendarmerie barracks in Abidjan, Ivory Coast, from October 01, 2011 to December 31, 2011. All candidates for inclusion in the corps army, aged 18 to 25 years, ivorian, from all regions of the Ivory Coast, were included in the study.EDTA tubes for Celluloseacetate electrophoresisat alkaline pHandblood count and dry tube for biochemical and virological testswere taken during donations. A total of 9526 were enrolled in this study. The median age of our patients with abnormal hemoglobins was 23 years with extremes of 18 and 25. The overall prevalence of abnormal hemoglobins was 15.07%. The prevalence was 9.54%, forHbS5,6 % for HbC and 0.052% for beta-thalassemia profile.The heterozygous AS (61.56%) and AC (35.38%), predominated. We noted 25 cases of sickle cell disease, including 14 major cases (0.97%) of homozygous SS and 11 cases (0.77%) of double heterozygous SC. We also noted 14 cases (0.97%) for CC homozygotes. The beta-thalassemia profile was weakly present in 0.35%.This study ofasymptomatic adults population, confirmed the high prevalence of HbS in Ivory Coast and the lack of a national program to fight against sickle cell disease. This should motivate the introduction of screening for abnormal hemoglobins to all the blood donors in Côte d’Ivoire

Published in	American Journal of Clinical and Experimental Medicine (Volume 1, Issue 3)
DOI	10.11648/j.ajcem.20130103.14
Page(s)	58-61
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Abnormal Hemoglobin–Gendarmerie Barracks

References

[1]	Cabannes R., Sendrail A., Pene F.,Sangare A., Sombo F M. et KpleFaget. Etude de l’hémotypologie des populations de l’Afrique de l’Ouest. Référenceparticulière aux populations IvoiriennesetPeulhs. Ann. Univ. Abidjan, série B (Médecine), 1979; XIII: 105-134.
[2]	Centre National de Transfusion Sanguine, Abidjan, Côte d’Ivoire. Rapport d’activité 2010.
[3]	Cabannes R., Nicolas C., Houvet D., FellenzC. et Sangare A. Etude hémotypologique et biologique des Abrons et des métiskoulango-Abrons. Ann. Univ. Abidjan, série B (Médecine), 1978 ; XII : 119-153
[4]	Cabannes R, Accuso A, Nicolas C. Répartition des hémoglobinesanormalesdans les populations Akan en Côte-d'Ivoire. Ann Univ ABJ Série B 1974 ; 8 : 158-68.
[5]	Cabannes R, Bonhomme J, Sendrail A. La drépanocytose, problème de santé publique. Ann Univ ABJ Série B 1970 ; 4 : 141-7.
[6]	Sangaré A. La douleurdrépanocytaire. J PanafrDouleur 1995 ; 1-12.
[7]	Segbena A, Buget A, Sangaré A. Drépanocytose et dépression : étudepréliminaire avec l'échelle de dépression de Hamilton. Med trop 1994 ; 54 : 47-52.
[8]	Elira-Dokekias A, N’golet O.L., Atipo T., Malanda F., Koko I., Montalembert M. Evaluation de la transfusion sanguine chez 112 patients drépanocytaires homozygotes au CHU de Brazzaville. Transf . Clin. Biol. 2009 ; 16(5-6) : 464-70.
[9]	Cissé R, Sano D, Traoré A, Chateil JF, Sawadogo A. Apport de l'imageriemédicaledans les manifestations viscérales de la drépanocytose. Med Afr Noire 1998 ; 45 : 226-30.
[10]	EliraDokekias A, Dokekias S. Profilclinique du sujetdrépanocytaire homozygote après l'âge de 30 ans. Tunis Med 2003 ; 81 : 101-8.
[11]	Bertrand E, Chauvet J, Le Bras M, Renambot J, Odi AM. Les signescardiaquesdans la drépanocytose de l'adulte, à propos de 111 cas homozygotes ouhétérozygotes. Cardiol trop.1975 ; 1 : 63-70.
[12]	Thuilliez V, Vierin Y. Le poids de la drépanocytose en milieu pédiatrique au Gabon. Sante Pub 1997 ; 3 : 45-60
[13]	H. Fabritius, A. Sangare, P. KPLE Faget et R. Cabannes.Les hémoglobines anormales et la drépanocytose en Côte d’Ivoire. Bull. Europ. De Physiopath. Respi., 1983 ; 19 : 282-383.
[14]	Tiendrebeogo et Sangare A. Tuberculose et hémoglobinopathies. Méd. Afr. Noire, 1978, 25 (4)
[15]	Cabannes R. et Sangare A. Les hémoglobines en Afriques de l’Ouest. Prémier congrès Africain de Transfusion Sanguine, Yamoussoukro (Côte d’Ivoire), Mars 1977.
[16]	Cabannes R. et Sangare A. Whatwasdone in IvoryCoast About Sicklecelldisease. International Symposium on Sicklecelldiseasehowarduniversity Washington, November 1976.
[17]	Elira-Dokekias A. Etude analytique des facteurs d’aggravation de la maladie drépanocytaire au congo. Pub. Méd. Afric. , 1994 ; 131 : 12-16.

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Sekongo Y. M., Kouamenan S., Siransy B. L., Ouattara B., Konan S., et al. (2014). Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire. American Journal of Clinical and Experimental Medicine, 1(3), 58-61. https://doi.org/10.11648/j.ajcem.20130103.14

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ACS Style

Sekongo Y. M.; Kouamenan S.; Siransy B. L.; Ouattara B.; Konan S., et al. Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire. Am. J. Clin. Exp. Med. 2014, 1(3), 58-61. doi: 10.11648/j.ajcem.20130103.14

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AMA Style

Sekongo Y. M., Kouamenan S., Siransy B. L., Ouattara B., Konan S., et al. Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire. Am J Clin Exp Med. 2014;1(3):58-61. doi: 10.11648/j.ajcem.20130103.14

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@article{10.11648/j.ajcem.20130103.14,
  author = {Sekongo Y. M. and Kouamenan S. and Siransy B. L. and Ouattara B. and Konan S. and Dembele B. and Tolo D.A. and Hyda J. and Kabore S. and Konate S.},
  title = {Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {1},
  number = {3},
  pages = {58-61},
  doi = {10.11648/j.ajcem.20130103.14},
  url = {https://doi.org/10.11648/j.ajcem.20130103.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20130103.14},
  abstract = {In Ivory Coast, Sickle cell disease is a public health problem. Approximately, there are 98,000 blood donors annually to the national blood transfusion center. Among these, some holders of abnormal hemoglobins are often diagnosed. The objective of this study is to determine the prevalence of abnormal hemoglobins during a mass balance for the integration into an army corps those are asymptomatic blood donors. This prospective and descriptive study took place in a gendarmerie barracks in Abidjan, Ivory Coast, from October 01, 2011 to December 31, 2011. All candidates for inclusion in the corps army, aged 18 to 25 years, ivorian, from all regions of the Ivory Coast, were included in the study.EDTA tubes for Celluloseacetate electrophoresisat alkaline pHandblood count and dry tube for biochemical and virological testswere taken during donations. A total of 9526 were enrolled in this study. The median age of our patients with abnormal hemoglobins was 23 years with extremes of 18 and 25. The overall prevalence of abnormal hemoglobins was 15.07%. The prevalence was 9.54%, forHbS5,6 % for HbC and 0.052% for beta-thalassemia profile.The heterozygous AS (61.56%) and AC (35.38%), predominated. We noted 25 cases of sickle cell disease, including 14 major cases (0.97%) of homozygous SS and 11 cases (0.77%) of double heterozygous SC. We also noted 14 cases (0.97%) for CC homozygotes. The beta-thalassemia profile was weakly present in 0.35%.This study ofasymptomatic adults population, confirmed the high prevalence of HbS in Ivory Coast and the lack of a national program to fight against sickle cell disease. This should motivate the introduction of screening for abnormal hemoglobins to all the blood donors in Côte d’Ivoire},
 year = {2014}
}

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TY - JOUR
T1 - Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire
AU - Sekongo Y. M.
AU - Kouamenan S.
AU - Siransy B. L.
AU - Ouattara B.
AU - Konan S.
AU - Dembele B.
AU - Tolo D.A.
AU - Hyda J.
AU - Kabore S.
AU - Konate S.
Y1 - 2014/01/10
PY - 2014
N1 - https://doi.org/10.11648/j.ajcem.20130103.14
DO - 10.11648/j.ajcem.20130103.14
T2 - American Journal of Clinical and Experimental Medicine
JF - American Journal of Clinical and Experimental Medicine
JO - American Journal of Clinical and Experimental Medicine
SP - 58
EP - 61
PB - Science Publishing Group
SN - 2330-8133
UR - https://doi.org/10.11648/j.ajcem.20130103.14
AB - In Ivory Coast, Sickle cell disease is a public health problem. Approximately, there are 98,000 blood donors annually to the national blood transfusion center. Among these, some holders of abnormal hemoglobins are often diagnosed. The objective of this study is to determine the prevalence of abnormal hemoglobins during a mass balance for the integration into an army corps those are asymptomatic blood donors. This prospective and descriptive study took place in a gendarmerie barracks in Abidjan, Ivory Coast, from October 01, 2011 to December 31, 2011. All candidates for inclusion in the corps army, aged 18 to 25 years, ivorian, from all regions of the Ivory Coast, were included in the study.EDTA tubes for Celluloseacetate electrophoresisat alkaline pHandblood count and dry tube for biochemical and virological testswere taken during donations. A total of 9526 were enrolled in this study. The median age of our patients with abnormal hemoglobins was 23 years with extremes of 18 and 25. The overall prevalence of abnormal hemoglobins was 15.07%. The prevalence was 9.54%, forHbS5,6 % for HbC and 0.052% for beta-thalassemia profile.The heterozygous AS (61.56%) and AC (35.38%), predominated. We noted 25 cases of sickle cell disease, including 14 major cases (0.97%) of homozygous SS and 11 cases (0.77%) of double heterozygous SC. We also noted 14 cases (0.97%) for CC homozygotes. The beta-thalassemia profile was weakly present in 0.35%.This study ofasymptomatic adults population, confirmed the high prevalence of HbS in Ivory Coast and the lack of a national program to fight against sickle cell disease. This should motivate the introduction of screening for abnormal hemoglobins to all the blood donors in Côte d’Ivoire
VL - 1
IS - 3
ER -

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Author Information

Sekongo Y. M.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Kouamenan S.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Siransy B. L.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Ouattara B.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Konan S.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Dembele B.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Tolo D.A.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Hyda J.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Kabore S.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France
Konate S.

Centre National de Transfusion Sanguine Abidjan C?te d’Ivoire BPV15 Abidjan Km4 Boulevard de Marseille, France

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APA Style

Sekongo Y. M., Kouamenan S., Siransy B. L., Ouattara B., Konan S., et al. (2014). Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire. American Journal of Clinical and Experimental Medicine, 1(3), 58-61. https://doi.org/10.11648/j.ajcem.20130103.14

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Sekongo Y. M.; Kouamenan S.; Siransy B. L.; Ouattara B.; Konan S., et al. Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire. Am. J. Clin. Exp. Med. 2014, 1(3), 58-61. doi: 10.11648/j.ajcem.20130103.14

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AMA Style

Sekongo Y. M., Kouamenan S., Siransy B. L., Ouattara B., Konan S., et al. Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire. Am J Clin Exp Med. 2014;1(3):58-61. doi: 10.11648/j.ajcem.20130103.14

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@article{10.11648/j.ajcem.20130103.14,
  author = {Sekongo Y. M. and Kouamenan S. and Siransy B. L. and Ouattara B. and Konan S. and Dembele B. and Tolo D.A. and Hyda J. and Kabore S. and Konate S.},
  title = {Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {1},
  number = {3},
  pages = {58-61},
  doi = {10.11648/j.ajcem.20130103.14},
  url = {https://doi.org/10.11648/j.ajcem.20130103.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20130103.14},
  abstract = {In Ivory Coast, Sickle cell disease is a public health problem. Approximately, there are 98,000 blood donors annually to the national blood transfusion center. Among these, some holders of abnormal hemoglobins are often diagnosed. The objective of this study is to determine the prevalence of abnormal hemoglobins during a mass balance for the integration into an army corps those are asymptomatic blood donors. This prospective and descriptive study took place in a gendarmerie barracks in Abidjan, Ivory Coast, from October 01, 2011 to December 31, 2011. All candidates for inclusion in the corps army, aged 18 to 25 years, ivorian, from all regions of the Ivory Coast, were included in the study.EDTA tubes for Celluloseacetate electrophoresisat alkaline pHandblood count and dry tube for biochemical and virological testswere taken during donations. A total of 9526 were enrolled in this study. The median age of our patients with abnormal hemoglobins was 23 years with extremes of 18 and 25. The overall prevalence of abnormal hemoglobins was 15.07%. The prevalence was 9.54%, forHbS5,6 % for HbC and 0.052% for beta-thalassemia profile.The heterozygous AS (61.56%) and AC (35.38%), predominated. We noted 25 cases of sickle cell disease, including 14 major cases (0.97%) of homozygous SS and 11 cases (0.77%) of double heterozygous SC. We also noted 14 cases (0.97%) for CC homozygotes. The beta-thalassemia profile was weakly present in 0.35%.This study ofasymptomatic adults population, confirmed the high prevalence of HbS in Ivory Coast and the lack of a national program to fight against sickle cell disease. This should motivate the introduction of screening for abnormal hemoglobins to all the blood donors in Côte d’Ivoire},
 year = {2014}
}

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