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Rhabdomyolysis Associated to Glossopharyngeal Edema: A Rare Side Effect of Diclofenac

Received: 21 November 2014    Accepted: 2 December 2014    Published: 15 December 2014
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Abstract

Rhabdomyolysis is a widely used non steroid anti-inflammatory drug. Rhabdomyolysis after taking Diclofenac is rarely reported, and the association to a glossopharyngeal edema has never been discussed. Here is a case of rhabdomyolysis associated to glossopharyngeal edema after taking 200 mg of Diclofenac. The patient was first diagnosed with para phenyl di-amine intoxication but the toxicological examinations were negative. The patient outcome was good after symptomatic treatment.

Published in American Journal of Clinical and Experimental Medicine (Volume 2, Issue 6)
DOI 10.11648/j.ajcem.20140206.18
Page(s) 161-164
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Diclofenac, Intoxication, Rhabdomyolysis, Glossopharyngeal Edema

References
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[2] KORE A.M. Toxicology of non steroidal anti inflammatory drugs. Vet. Clin. of North Am. 1990, 20(2): 419-430.
[3] Hopkins P. M.. Anaesthesia and the sex-linked dystrophies: between a rock and a hard place. British Journal of Anaesthesia. 2010,104 (4): 397–400.
[4] 4 George D. Giannoglou ⁎, Yiannis S. Chatzizisis, Gesthimani Misirli. The syndrome of rhabdomyolysis: Pathophysiology and diagnosis. European Journal of Internal Medicine. 2007;18:90–100.
[5] Delrio FG, Park Y, Herzlich B, Grob D. Case report: diclofenac-induced rhabdomyolysis. Am J Med Sci 1996; 312:95-7.
[6] Knobloch K, Rossner D, Gössling T, Lichtenberg A, Richter M, Krettek C. Rhabdomyolysis after administration of diclofenac. Unfallchirurg 2005; 108:415-7.
[7] Ahmet Güzel, Betül Orhaner Biner, Serap Karasalihoğlu, Hakan Aylanç. Fatal Acute Diclofenac-Induced Rhabdomyolysis in A Pediatric Patient. Balkan Med J 2011; 28: 102-103.
[8] Mahmood Al kindy, Vidia Limaye, Pravin Hissaria. Meloxicam induced rhabdomyolisys in the context of acute cross river infection. Allergy Asthma Immunol Res.2012 January 4(1); 52-54.
[9] Teresa J. Coco and Ann E. Klasner. Drug-induced rhabdomyolysis. Current Opinion in Pediatrics.2004; 16: 206–210.
[10] Kallel H, Chelly H, Dammak H, Bahloul M, Ksibi H, Hamida CB, et al. Clinical Manifestations of systemic paraphenylene diamine intoxication. J Nephrol 2005;18:308-11.
[11] Krishnaswamy Sampathkumar, Yesudas Santhakumari Sooraj, Rajappannair Prabha Ajeshkumar, Amol Ramesh Mahaldar, Ramakrishnan Muthiah. Rhabdomyolysis due to hair dye poisoning: An emerging threat. Indian Journal of critical care medicine. 2007; 11(4):212-214.
[12] Cervellin G, Comelli I, Lippi G. Rhabdomyolysis: historicalbackground, clinical, diagnostic and therapeutic features. Clin Chem Lab Med 2010;48(6):749–56.
Cite This Article
  • APA Style

    Hicham Bakkali, Lahcen Belyamani, Salahedine Massou, Loukmane Elwartiti, Khalil Aboulaala, et al. (2014). Rhabdomyolysis Associated to Glossopharyngeal Edema: A Rare Side Effect of Diclofenac. American Journal of Clinical and Experimental Medicine, 2(6), 161-164. https://doi.org/10.11648/j.ajcem.20140206.18

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    ACS Style

    Hicham Bakkali; Lahcen Belyamani; Salahedine Massou; Loukmane Elwartiti; Khalil Aboulaala, et al. Rhabdomyolysis Associated to Glossopharyngeal Edema: A Rare Side Effect of Diclofenac. Am. J. Clin. Exp. Med. 2014, 2(6), 161-164. doi: 10.11648/j.ajcem.20140206.18

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    AMA Style

    Hicham Bakkali, Lahcen Belyamani, Salahedine Massou, Loukmane Elwartiti, Khalil Aboulaala, et al. Rhabdomyolysis Associated to Glossopharyngeal Edema: A Rare Side Effect of Diclofenac. Am J Clin Exp Med. 2014;2(6):161-164. doi: 10.11648/j.ajcem.20140206.18

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  • @article{10.11648/j.ajcem.20140206.18,
      author = {Hicham Bakkali and Lahcen Belyamani and Salahedine Massou and Loukmane Elwartiti and Khalil Aboulaala and Hicham Balkhi and Charqui Haimeur},
      title = {Rhabdomyolysis Associated to Glossopharyngeal Edema: A Rare Side Effect of Diclofenac},
      journal = {American Journal of Clinical and Experimental Medicine},
      volume = {2},
      number = {6},
      pages = {161-164},
      doi = {10.11648/j.ajcem.20140206.18},
      url = {https://doi.org/10.11648/j.ajcem.20140206.18},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20140206.18},
      abstract = {Rhabdomyolysis is a widely used non steroid anti-inflammatory drug. Rhabdomyolysis after taking Diclofenac is rarely reported, and the association to a glossopharyngeal edema has never been discussed. Here is a case of rhabdomyolysis associated to glossopharyngeal edema after taking 200 mg of Diclofenac. The patient was first diagnosed with para phenyl di-amine intoxication but the toxicological examinations were negative. The patient outcome was good after symptomatic treatment.},
     year = {2014}
    }
    

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    AU  - Lahcen Belyamani
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    JO  - American Journal of Clinical and Experimental Medicine
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    AB  - Rhabdomyolysis is a widely used non steroid anti-inflammatory drug. Rhabdomyolysis after taking Diclofenac is rarely reported, and the association to a glossopharyngeal edema has never been discussed. Here is a case of rhabdomyolysis associated to glossopharyngeal edema after taking 200 mg of Diclofenac. The patient was first diagnosed with para phenyl di-amine intoxication but the toxicological examinations were negative. The patient outcome was good after symptomatic treatment.
    VL  - 2
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    ER  - 

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Author Information
  • Department of Emergency, Military Training Hospital Med V, Rabat, Morocco

  • Department of Emergency, Military Training Hospital Med V, Rabat, Morocco

  • Department of Anesthesiology and Critical Care, Military Training Hospital Med V, Rabat, Morocco

  • Department of Anesthesiology and Critical Care, Military Training Hospital Med V, Rabat, Morocco

  • Department of Anesthesiology and Critical Care, Military Training Hospital Med V, Rabat, Morocco

  • Department of Anesthesiology and Critical Care, Military Training Hospital Med V, Rabat, Morocco

  • Department of Anesthesiology and Critical Care, Military Training Hospital Med V, Rabat, Morocco

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