3DCRT Versus RapidArc in Terms of Iso-Dose Distribution, Dose Volume Histogram (DVH) and Organs at Risk for Esophageal Cancer (EC) Dosimetric Study
American Journal of Clinical and Experimental Medicine
Volume 5, Issue 4, July 2017, Pages: 123-133
Received: May 10, 2017; Accepted: May 19, 2017; Published: Jun. 28, 2017
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Authors
Saud. H. Allehyani, Physics Department, College of Applied Science, Umm ALQura University, Makkah, Saudi Arabia
Huda. A. Sharyan, Physics Department, College of Applied Science, Umm ALQura University, Makkah, Saudi Arabia
Aida. R. Tolba, Physics Department, College of Applied Science, Umm ALQura University, Makkah, Saudi Arabia; Radiotherapy and Nuclear Medicine Department, National Cancer Institute, Cairo University, Cairo, Egypt
Rmadan. A. Hassan, Physics Department, College of Applied Science, Umm ALQura University, Makkah, Saudi Arabia; Radiotherapy and Nuclear Medicine Department, National Cancer Institute, Cairo University, Cairo, Egypt
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Abstract
Purpose: To compare (3D-CRT) to RapidArc planning using (LNAC of 6 MV) in terms of dosimetric outcomes of iso-dose distribution, dose volume histogram (DVH), PTV and at risk organs in 5 patients with Esophageal cancer (EC). Methods: Plans were created for 5 patients with EC who had received radical RapidArc treatment from 2012 to 2014 at KAMC (King Abdullah Medical City). Results: RapidArc plan showed a more homogeneous dose distribution in PTV, achieving an HI of 1.112 ± 0.030 compared with 1.096 ± 0.029 in the 3D-CRT plan. However, RapidArc and 3D-CRT achieved nearly equal in both modalities with average value of (0.130 ± 0.052) in RapidArc compared to (0.134 ± 0.054) in 3D-CRT, (p = 0.061) in terms of CI values and Target coverage index (TCI) was (0.093 ± 0.032) in RapidArcand and (0.099 ±0.058) in 3D-CRT, (p = 0.767). Additionally, regarding OARs, the mean and maximum dose in Spinal Cord was lower in RapidArc with a low percentage of the volume receiving low doses. Left and Right Lungs were within tolerance in RapidArc and 3D-CRT. RT. Kidney was lower in RapidArc, while LT Kidney was lower in 3D-CRT. For Heart, the maximum dose was within tolerance criteria in RapidArc but exceeded the criteria in 3D-CRT at 60.97 Gy. For the spinal cord, the maximum dose was notably low and did not exceed 1.91 Gy in RapidArc, while it exceeded the acceptable limit in 3D-CRT. Conclusions: (VMAT) is superior to 3D-CRT in term of PTV, conformity and homogeneity. This study suggests that VMAT class solution is the superior treatment option.
Keywords
Planning Tumor Volume, Organs at Risk, Conformity Index, Heterogeneity Index, Esophageal Cancer
To cite this article
Saud. H. Allehyani, Huda. A. Sharyan, Aida. R. Tolba, Rmadan. A. Hassan, 3DCRT Versus RapidArc in Terms of Iso-Dose Distribution, Dose Volume Histogram (DVH) and Organs at Risk for Esophageal Cancer (EC) Dosimetric Study, American Journal of Clinical and Experimental Medicine. Vol. 5, No. 4, 2017, pp. 123-133. doi: 10.11648/j.ajcem.20170504.14
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Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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