Advances in Surgical Sciences

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A Review of the Molecular Pathways of Oncogenic HPV and Targeted the Rapies in Carcinoma of the Uterine Cervix

Received: 25 February 2017    Accepted: 25 March 2017    Published: 12 April 2017
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Abstract

Cervical carcinoma is a preventable disease based on its etiopathogenesis. This relies highly on its prompt diagnosis and treatment based on effective screening and treatment methods. Knowledge of its molecular pathways will drive the use of targeted therapies in the treatment of the disease. The objectives of this review are: to explore the biology and immunology of HPV; the various molecular pathways through which oncogenic HPV destroys normal cervical cells; and targeted therapies. Several molecular pathways have been identified but the use of drugs to act on specified molecular targets are at different stages of clinical trials.

DOI 10.11648/j.ass.20170501.11
Published in Advances in Surgical Sciences (Volume 5, Issue 1, February 2017)
Page(s) 1-6
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Cervical Cancer, Molecular Pathways, Targeted Therapies

References
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    Boniface Uji Ago. (2017). A Review of the Molecular Pathways of Oncogenic HPV and Targeted the Rapies in Carcinoma of the Uterine Cervix. Advances in Surgical Sciences, 5(1), 1-6. https://doi.org/10.11648/j.ass.20170501.11

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    ACS Style

    Boniface Uji Ago. A Review of the Molecular Pathways of Oncogenic HPV and Targeted the Rapies in Carcinoma of the Uterine Cervix. Adv. Surg. Sci. 2017, 5(1), 1-6. doi: 10.11648/j.ass.20170501.11

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    AMA Style

    Boniface Uji Ago. A Review of the Molecular Pathways of Oncogenic HPV and Targeted the Rapies in Carcinoma of the Uterine Cervix. Adv Surg Sci. 2017;5(1):1-6. doi: 10.11648/j.ass.20170501.11

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  • @article{10.11648/j.ass.20170501.11,
      author = {Boniface Uji Ago},
      title = {A Review of the Molecular Pathways of Oncogenic HPV and Targeted the Rapies in Carcinoma of the Uterine Cervix},
      journal = {Advances in Surgical Sciences},
      volume = {5},
      number = {1},
      pages = {1-6},
      doi = {10.11648/j.ass.20170501.11},
      url = {https://doi.org/10.11648/j.ass.20170501.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ass.20170501.11},
      abstract = {Cervical carcinoma is a preventable disease based on its etiopathogenesis. This relies highly on its prompt diagnosis and treatment based on effective screening and treatment methods. Knowledge of its molecular pathways will drive the use of targeted therapies in the treatment of the disease. The objectives of this review are: to explore the biology and immunology of HPV; the various molecular pathways through which oncogenic HPV destroys normal cervical cells; and targeted therapies. Several molecular pathways have been identified but the use of drugs to act on specified molecular targets are at different stages of clinical trials.},
     year = {2017}
    }
    

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    AB  - Cervical carcinoma is a preventable disease based on its etiopathogenesis. This relies highly on its prompt diagnosis and treatment based on effective screening and treatment methods. Knowledge of its molecular pathways will drive the use of targeted therapies in the treatment of the disease. The objectives of this review are: to explore the biology and immunology of HPV; the various molecular pathways through which oncogenic HPV destroys normal cervical cells; and targeted therapies. Several molecular pathways have been identified but the use of drugs to act on specified molecular targets are at different stages of clinical trials.
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Author Information
  • Department of Obstetrics and Gynaecology, University of Calabar Teaching Hospital, Calabar, Nigeria

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