International Journal of Clinical Urology

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A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country

Received: 05 March 2017    Accepted: 22 April 2017    Published: 11 October 2017
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Abstract

A 57-year-old woman with chronic hemodialysis for 16 years, who presented at the Avicenna hospital in Marrakesh with fever and hepatosplenomegaly. Three months earlier, he received 2 units of packed red blood cells. Laboratory studies indicated hemolytic anemia (hemoglobin, 9.5 mg/dl) and thrombocytopenia (platelet count, 105000/mm2). Malaria smear was consistent with Plasmodium malariae. The level of parasetemia was 1% (10 per 1000 erythrocytes). As a result, the patient's antimalarial therapy was continued for a total of 7 days followed by mefloquine for 7 days once the blood smear results revealed P. malariae infection. Evolution was favorable after antimalarial therapy with the disappeanrance of fever and hepatosplenomegaly. The control of parasitaemia remained negative until 28 days. This is the first case of hepatosplenomegaly secondary to blood transfusion related Plasmodium malariae infection in a non-endemic country in chronic hemodialysis.

DOI 10.11648/j.ijcu.20170101.14
Published in International Journal of Clinical Urology (Volume 1, Issue 1, December 2017)
Page(s) 15-18
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Chronic Hemodialisis, Malaria Transfusion, Plasmodium malariae

References
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[2] S. Haydoura et al. Transfusion-related Plasmodium ovale malaria complicated by acute respiratory distress syndrome (ARDS) in a non-endemic country Parasitology International 60 (2011) 114–116.
[3] Laishram DD, Sutton PL, Nanda N, Sharma VL, Sobti RC, Carlton JM, Joshi H. The complexities of malaria disease manifestations with a focus on asymptomatic malaria. Malar J. 2012; 12: 29.
[4] Benito A and Rubio JM. Usefulness of Seminested Polymerase Chain Reaction for Screening Blood Donors at Risk for Malaria in Spain. Emerging Infectious Diseases. 2001; 7, (6): 1068.
[5] Bemelman F, De Blok K, De Vries P and al. falciparum malaria transmitted by a thick blood smear negative kidney donor. Scandinavian journal of infectious diseases. 2004; 36: 769-771.
[6] Nahlen BL, Lobel HO, Cannon SE, Campbell CC. Reassessment of blood donor selection criteria for United States travelers to malarious areas. Transfus 1991; 31: 798–804.
[7] Mungai M, Tegtmeier G, Chamberland M, Parise M. Transfusion transmitted malaria in the United States from 1963 through 1999. N Engl J Med 2001; 344: 1973–8.
[8] Candolfi E. Transfusion transmitted malaria, preventive measures. Transfusion Clinique et Biologique. 2005; 12: 107–113.
[9] Silvie O, Thellier M, Rosenheim M, Datry A, Lavigne P, Danis M, et al. Potential value of Plasmodium falciparum-associated antigen and antibody detection for screening of blood donors to prevent transfusion-transmitted malaria. Transfusion 2002; 42: 357–62.
[10] Legros F, Danis M. Malaria in France in 1998. CNRMI Bull 1999; 15: 1-34.
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[12] Transfusion-Transmitted Malaria: How Satisfactory Are Current Preventative Measures? The American Journal of Medicine (2006) 119, e1-e2.
[13] Danic B. Clinical selection of blood donors. Transfusion Clinique et Biologique. 2003; 10: 227-233.
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[15] Kitchen A, Chiodini P. Malaria and blood transfusion. Vox Sanguinis. 2006; 90: 77–84.
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[17] Tayou Tagny C, Mbanya D, Garraud O and all. Blood safety: Malaria and blood donation in Africa. Transfusion Clinique et Biologique. 2007; 14: 481–486.
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Author Information
  • Department of Parasitology, University of Cadi Ayyad, Medical School, Marrakech, Morocco

  • Department of Hematology Transfusion, University of Cadi Ayyad, Medical School, Marrakech, Morocco

  • Department of Nephrology Hemodialisis, University of Cadi Ayyad, Medical School, Marrakech, Morocco

  • Department of Hematology Transfusion, University of Cadi Ayyad, Medical School, Marrakech, Morocco

  • Department of Hematology Transfusion, University of Cadi Ayyad, Medical School, Marrakech, Morocco

  • Department of Internal Medicine, University of Cadi Ayyad, Medical School, Marrakech, Morocco

  • Department of Nephrology Hemodialisis, University of Cadi Ayyad, Medical School, Marrakech, Morocco

  • Department of Parasitology, University of Cadi Ayyad, Medical School, Marrakech, Morocco

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  • APA Style

    El Mezouari El Mostafa, Benjelloun Imane, Belarbi Marouane, Ait Ameur Mustapha, Chakour Mohamed, et al. (2017). A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country. International Journal of Clinical Urology, 1(1), 15-18. https://doi.org/10.11648/j.ijcu.20170101.14

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    ACS Style

    El Mezouari El Mostafa; Benjelloun Imane; Belarbi Marouane; Ait Ameur Mustapha; Chakour Mohamed, et al. A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country. Int. J. Clin. Urol. 2017, 1(1), 15-18. doi: 10.11648/j.ijcu.20170101.14

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    AMA Style

    El Mezouari El Mostafa, Benjelloun Imane, Belarbi Marouane, Ait Ameur Mustapha, Chakour Mohamed, et al. A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country. Int J Clin Urol. 2017;1(1):15-18. doi: 10.11648/j.ijcu.20170101.14

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  • @article{10.11648/j.ijcu.20170101.14,
      author = {El Mezouari El Mostafa and Benjelloun Imane and Belarbi Marouane and Ait Ameur Mustapha and Chakour Mohamed and Zyani Mohamed and Zemraoui Nadir and Moutaj Redouane},
      title = {A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country},
      journal = {International Journal of Clinical Urology},
      volume = {1},
      number = {1},
      pages = {15-18},
      doi = {10.11648/j.ijcu.20170101.14},
      url = {https://doi.org/10.11648/j.ijcu.20170101.14},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijcu.20170101.14},
      abstract = {A 57-year-old woman with chronic hemodialysis for 16 years, who presented at the Avicenna hospital in Marrakesh with fever and hepatosplenomegaly. Three months earlier, he received 2 units of packed red blood cells. Laboratory studies indicated hemolytic anemia (hemoglobin, 9.5 mg/dl) and thrombocytopenia (platelet count, 105000/mm2). Malaria smear was consistent with Plasmodium malariae. The level of parasetemia was 1% (10 per 1000 erythrocytes). As a result, the patient's antimalarial therapy was continued for a total of 7 days followed by mefloquine for 7 days once the blood smear results revealed P. malariae infection. Evolution was favorable after antimalarial therapy with the disappeanrance of fever and hepatosplenomegaly. The control of parasitaemia remained negative until 28 days. This is the first case of hepatosplenomegaly secondary to blood transfusion related Plasmodium malariae infection in a non-endemic country in chronic hemodialysis.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country
    AU  - El Mezouari El Mostafa
    AU  - Benjelloun Imane
    AU  - Belarbi Marouane
    AU  - Ait Ameur Mustapha
    AU  - Chakour Mohamed
    AU  - Zyani Mohamed
    AU  - Zemraoui Nadir
    AU  - Moutaj Redouane
    Y1  - 2017/10/11
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    DO  - 10.11648/j.ijcu.20170101.14
    T2  - International Journal of Clinical Urology
    JF  - International Journal of Clinical Urology
    JO  - International Journal of Clinical Urology
    SP  - 15
    EP  - 18
    PB  - Science Publishing Group
    SN  - 2640-1355
    UR  - https://doi.org/10.11648/j.ijcu.20170101.14
    AB  - A 57-year-old woman with chronic hemodialysis for 16 years, who presented at the Avicenna hospital in Marrakesh with fever and hepatosplenomegaly. Three months earlier, he received 2 units of packed red blood cells. Laboratory studies indicated hemolytic anemia (hemoglobin, 9.5 mg/dl) and thrombocytopenia (platelet count, 105000/mm2). Malaria smear was consistent with Plasmodium malariae. The level of parasetemia was 1% (10 per 1000 erythrocytes). As a result, the patient's antimalarial therapy was continued for a total of 7 days followed by mefloquine for 7 days once the blood smear results revealed P. malariae infection. Evolution was favorable after antimalarial therapy with the disappeanrance of fever and hepatosplenomegaly. The control of parasitaemia remained negative until 28 days. This is the first case of hepatosplenomegaly secondary to blood transfusion related Plasmodium malariae infection in a non-endemic country in chronic hemodialysis.
    VL  - 1
    IS  - 1
    ER  - 

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