Comparative Study of Precancerous Lesions of the Uterine Cervix Among Users and Non-Users of Combined Oral Contraceptive Pills in Jos, Nigeria
International Journal of Clinical Oncology and Cancer Research
Volume 3, Issue 3, June 2018, Pages: 35-40
Received: Jan. 3, 2018;
Accepted: Aug. 31, 2018;
Published: Sep. 27, 2018
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Yakubu Emmanuel Nyam, Department of Obstetrics and Gynaecology, Jos University Teaching Hospital, Jos, Nigeria
Ajen Stephen Anzaku, Department of Obstetrics and Gynaecology, Bingham University Teaching Hospital, Jos, Nigeria
Innocent Emmanuel, Department of Histopathology, Jos University Teaching Hospital, Jos, Nigeria
Isikhuemen Ehikoya Maradona, Department of Obstetrics and Gynaecology, University of Benin Teaching Hospital, Benin City, Nigeria
Ekwedigwe Chinedu Kenneth, National Obstetric Fistula Centre, Abakaliki, Nigeria
Daru Patrick Haruna, Department of Obstetrics and Gynaecology, Jos University Teaching Hospital, Jos, Nigeria
Ocheke Ngozi Amaka, Department of Obstetrics and Gynaecology, Jos University Teaching Hospital, Jos, Nigeria
Ujah Achanya Otobo Innocent, Department of Obstetrics and Gynaecology, Jos University Teaching Hospital, Jos, Nigeria
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Combined oral contraceptive pills (COCP) use, is link to the development of precancerous cervical lesions. There are variations in reports across studied populations. Our study was a comparative, cross-sectional study. SPSS version 20 (IBM, Armonk, NY, USA) was used for data analysis and P-Value < 0.05 was considered statistically significant. The Prevalence of precancerous cervical lesions in the Exposed and Control groups were 16.4% (9/55) and 14.5% (8/55) respectively (P = of 0.79). In the exposed group, four out of the nine women that had abnormal cervical cytology results had high grade squamous intra-epithelial lesions (HGSIL) while only one out of 8 women that had abnormal cytology results in the control group had HGSIL. We found no significant difference in the prevalence of pre-cancerous cervical lesions between users and non-users of COCP. However, women who used COCP had higher cases of HGSIL when compared with the control group. Therefore, we suggest relatively short schedule of cervical cytology screening for this group of women relative to the general population.
Papanicolaou Smear Test, Combined Oral Contraceptive Pills, Precancerous Cervical Lesions
To cite this article
Yakubu Emmanuel Nyam,
Ajen Stephen Anzaku,
Isikhuemen Ehikoya Maradona,
Ekwedigwe Chinedu Kenneth,
Daru Patrick Haruna,
Ocheke Ngozi Amaka,
Ujah Achanya Otobo Innocent,
Comparative Study of Precancerous Lesions of the Uterine Cervix Among Users and Non-Users of Combined Oral Contraceptive Pills in Jos, Nigeria, International Journal of Clinical Oncology and Cancer Research.
Vol. 3, No. 3,
2018, pp. 35-40.
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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