In-vivo Antidiabetic Activity of Methanolic Extract of Euphorbia hirta L
International Journal of Diabetes and Endocrinology
Volume 2, Issue 3, September 2017, Pages: 36-39
Received: Feb. 24, 2017; Accepted: Jun. 6, 2017; Published: Jul. 27, 2017
Views 1808      Downloads 155
Sangeeta Devi, Department of Botany Govt. Degree College Doda, University of Jammu, Jammu and Kashmir, India
Muneesh Kumar, Department of Zoology Govt. Degree College Doda, University of Jammu, Jammu and Kashmir, India
Article Tools
Follow on us
Diabetes is a metabolic disorder which results from pancreatic beta cells dysfunction & insulin resistance and are characterized by hyperglycemia. The in-vivo anti-diabetic potential of E. hirta L. was also determined so as to justify the traditional usage of the plant in treating diabetes. The result of the present study confirmed that the methanolic extract of E. hirta possess significant anti-diabetic activity in-vivo, this shows that the plants has the potential for the development of drugs in combating diabetes.
Diabetes, Euphorbia hirta, Hyperglycemia, in-vivo
To cite this article
Sangeeta Devi, Muneesh Kumar, In-vivo Antidiabetic Activity of Methanolic Extract of Euphorbia hirta L, International Journal of Diabetes and Endocrinology. Vol. 2, No. 3, 2017, pp. 36-39. doi: 10.11648/j.ijde.20170203.11
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Satyanarayana, U., Chakrapani, U., (2004). Biochemistry second edition. pp. 669.
Conget, (2002). Diagnosis, classification and pathogenesis of diabetes mellitus. Rev. Esp. cardiol, 55(5): 528-35.
Harbrone, S. B., Baxter, H., (1995). Phytochemical Dictionary. A handbook of bioactive compounds from plants Taylor and Francis, London.
Sikarwar, M. S., Patil, M. B., Kokate, C. K., Sharma, S., and Bhat, V., (2009). Antidiabetic activity of Neriumindicum leaf extract in alloxan-induced diabetic rats. Journal of young pharmacist. 1(4): 330-335.
Arunachalam. K., Parimelazhagan, T., (2012). Antioxidant properties from methanol extract of Ficustalboti bark on diabetic rats induced by Streptozotocin. Asian pac. Journal of Reproduction. 3(2), 97-105.
Matthew, O., Olusola, L., and Oluwole, A. M., (2012). Preliminary study of Hypoglycaemic and Hypolipidemic activity of aqueous root extract of Ricinus Communis in Alloxan-Induced Diabetic Rats. Journal of Physiology and Pharmacology Advances. 2(10): 354-359.
Ashish, B., and swapinal, G., (2011). Hypoglycaemic effect of polyherbal formulation in Alloxan Induced Diabetic Rats. Pharmacology online. 3, 764-773.
Sabu, M. C., and Kuttan, R., (2002). Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J. Ethanopharmacol., 81: 155-160.
O. H. Osmani, D. S. Sekar, K. L. Senthil Kumar, R. K. Sahu, A. Roy, ( 2009) Biomedical and Pharmacological Journal, 2(2): 339-343.
M. B. Krishna, S. Nammi, M. K. Kota, R. V. Krishna Rao, N. Koteswara Rao, A. Annapurna, (2004) J. Ethnopharmacol, 91: 95-98.
U. Sharma, R. K. Sahu, A. Roy, D. K. Golwala, Journal of Young Pharmacists 2010, 2(3): 255-260. [4] D. Loew, M. Kaszkin, Phytother. Res., 2002, 16: 705-711.
El-Mahmood MA. (2009). Antibacterial activity of crude extracts of Euphorbia hirta against some bacteria associated with enteric infections; 3(7): 498-505.
Kumar S, Malhotra R, Kumar D. (2010) Euphorbia hirta L: Its chemistry, traditional and medicinal uses, and pharmacological activities; 4: 58- 61.
Anozie VL. (1981) God’s healing power in plants. Clin Pharm Herb Medium; 7: 23-25.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186