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Short Term Follow up for Diabetic Patients Presented with Acute STEMI Undergoing Preventive Versus Culprit Lesion in Primary Percutaneous Coronary Intervention

Received: 2 November 2019    Accepted: 23 November 2019    Published: 4 December 2019
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Abstract

Objectives: This study aimed to evaluate the short term follow up for diabetic patients presented with acute STEMI underwent preventive percutaneous coronary intervention. Background: preventive PCI appears to be safe as culprit artery PCI with effective reduction of refractory angina and repeated revascularization in selected patients but no benefit on mortality or recurrent MI. Methods: Our study was a prospective, observational study conducted at multicenter hospitals included 120 diabetic patients admitted with acute STEMI and multivessels CAD at National Heart Institute, Menofia university hospital, police academy center and some private hospitals patients from June 2017 to august 2018, group (A) Consisted of 70 diabetic patients with acute STEMI undergone preventive PCI in whom PCI will be done for culprit & non culprit lesions, group (B) Consisted of 50 diabetic patients with acute STEMI undergone PCI for culprit lesion only. Results: The total revascularization group were significantly less suffering from refractory angina 5 (7.1%) vs 15 (30.0%), p= <0.001 and less re-hospitalized for cardiac causes 14 (20.0%) vs 22 (44.0%), p= 0.005, cardiac mortality was 2 patients 0 (0.0%) vs 2 (4%) p= 0.092. Conclusion: The preventive PCI appears to be safe as culprit artery PCI with effective reduction of refractory angina and repeated revascularization but no benefit on mortality or recurrent MI in selected hemodynamically stable STEMI diabetic patients with multivessel disease.

Published in Cardiology and Cardiovascular Research (Volume 3, Issue 4)
DOI 10.11648/j.ccr.20190304.15
Page(s) 99-103
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

STEMI, Multivessels CAD, Preventive PCI

References
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[3] Bates E. R. Tamis-Holland J E, Bittl JA, et al. PCI Strategies in Patients with ST-Segment Elevation Myocardial Infarction and Multi-vessel Coronary Artery Disease. J Am CollCardiol. 2016; 68 (10): 1066–81.
[4] Gershlick AH, Khan JN, Kelly DJ, et al. Randomized trial of complete versus lesion-only revascularization in patients under- going primary percutaneous coronary intervention for STEMI and multi-vessel Disease: the CvLPRIT trial. J Am CollCardiol. 2015; 65: 963–72.
[5] Goldstein JA, Demetriou D, Grines CL, et al. Multiple complex coronary plaques in patients with acute myocardial infarction. N Engl J Med, 2000; 343: 915–922.
[6] Kalarus Z, Lenarczyk R, Kowalczyk J, et al. Importance of complete revascularization in patients with acute myocardial infarction treated with percutaneous coronary intervention. Am Heart J 2007; 153: 304-312.
[7] Keeley EC, Boura JA and Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative re- view of 23 randomized trials. Lancet. 2003; 361: 13–20.
[8] Lee HW, Hong TJ, Yang Mi J, et al. Comparison of infarct- related artery vs multivessel revascularization in ST-segment elevation myocardial infarction with multivessel disease: analysis from Korea Acute Myocardial Infarction registry (KAMIR). Cardiol J 2012; 19, 3: 256-266.
[9] Levine GN, O’Gara PT, Bates ER, et al. 2015 ACC/AHA/SCAI focused update on primary percutaneous coronary intervention for patients with ST- elevation myocardial infarction: an update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST- Elevation Myocardial Infarction. J Am Coll Cardiol 2015; 67: 1235–50.
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[14] Qarawani D, Nahir M, Abboud M, et al. Culprit only versus complete coronary revascularization during primary PCI. Int J Cardiol. 2008; 123: 288–92.
[15] Sorajja P, Gersh BJ, Cox DA, et al. Impact of multi-vessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction. Eur Heart J 2007; 28: 1709–16.
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[17] Vlaar PJ, Mahmoud KD, Holmes DR, et al. Culprit vessel only versus multi-vessel and staged percutaneous coronary intervention for multi-vessel disease in patients presenting with ST-segment elevation myocardial infarction: a pairwise and network meta-analysis. J Am Coll Cardiol. 2011; 58: 692–703.
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Cite This Article
  • APA Style

    Mohamed Elsayed Shuman, Ahmed Abdallah Mostafa, Ghada Mahmoud Soltan, Abdalla Mostafa Kamal. (2019). Short Term Follow up for Diabetic Patients Presented with Acute STEMI Undergoing Preventive Versus Culprit Lesion in Primary Percutaneous Coronary Intervention. Cardiology and Cardiovascular Research, 3(4), 99-103. https://doi.org/10.11648/j.ccr.20190304.15

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    ACS Style

    Mohamed Elsayed Shuman; Ahmed Abdallah Mostafa; Ghada Mahmoud Soltan; Abdalla Mostafa Kamal. Short Term Follow up for Diabetic Patients Presented with Acute STEMI Undergoing Preventive Versus Culprit Lesion in Primary Percutaneous Coronary Intervention. Cardiol. Cardiovasc. Res. 2019, 3(4), 99-103. doi: 10.11648/j.ccr.20190304.15

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    AMA Style

    Mohamed Elsayed Shuman, Ahmed Abdallah Mostafa, Ghada Mahmoud Soltan, Abdalla Mostafa Kamal. Short Term Follow up for Diabetic Patients Presented with Acute STEMI Undergoing Preventive Versus Culprit Lesion in Primary Percutaneous Coronary Intervention. Cardiol Cardiovasc Res. 2019;3(4):99-103. doi: 10.11648/j.ccr.20190304.15

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  • @article{10.11648/j.ccr.20190304.15,
      author = {Mohamed Elsayed Shuman and Ahmed Abdallah Mostafa and Ghada Mahmoud Soltan and Abdalla Mostafa Kamal},
      title = {Short Term Follow up for Diabetic Patients Presented with Acute STEMI Undergoing Preventive Versus Culprit Lesion in Primary Percutaneous Coronary Intervention},
      journal = {Cardiology and Cardiovascular Research},
      volume = {3},
      number = {4},
      pages = {99-103},
      doi = {10.11648/j.ccr.20190304.15},
      url = {https://doi.org/10.11648/j.ccr.20190304.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20190304.15},
      abstract = {Objectives: This study aimed to evaluate the short term follow up for diabetic patients presented with acute STEMI underwent preventive percutaneous coronary intervention. Background: preventive PCI appears to be safe as culprit artery PCI with effective reduction of refractory angina and repeated revascularization in selected patients but no benefit on mortality or recurrent MI. Methods: Our study was a prospective, observational study conducted at multicenter hospitals included 120 diabetic patients admitted with acute STEMI and multivessels CAD at National Heart Institute, Menofia university hospital, police academy center and some private hospitals patients from June 2017 to august 2018, group (A) Consisted of 70 diabetic patients with acute STEMI undergone preventive PCI in whom PCI will be done for culprit & non culprit lesions, group (B) Consisted of 50 diabetic patients with acute STEMI undergone PCI for culprit lesion only. Results: The total revascularization group were significantly less suffering from refractory angina 5 (7.1%) vs 15 (30.0%), p= <0.001 and less re-hospitalized for cardiac causes 14 (20.0%) vs 22 (44.0%), p= 0.005, cardiac mortality was 2 patients 0 (0.0%) vs 2 (4%) p= 0.092. Conclusion: The preventive PCI appears to be safe as culprit artery PCI with effective reduction of refractory angina and repeated revascularization but no benefit on mortality or recurrent MI in selected hemodynamically stable STEMI diabetic patients with multivessel disease.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Short Term Follow up for Diabetic Patients Presented with Acute STEMI Undergoing Preventive Versus Culprit Lesion in Primary Percutaneous Coronary Intervention
    AU  - Mohamed Elsayed Shuman
    AU  - Ahmed Abdallah Mostafa
    AU  - Ghada Mahmoud Soltan
    AU  - Abdalla Mostafa Kamal
    Y1  - 2019/12/04
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ccr.20190304.15
    DO  - 10.11648/j.ccr.20190304.15
    T2  - Cardiology and Cardiovascular Research
    JF  - Cardiology and Cardiovascular Research
    JO  - Cardiology and Cardiovascular Research
    SP  - 99
    EP  - 103
    PB  - Science Publishing Group
    SN  - 2578-8914
    UR  - https://doi.org/10.11648/j.ccr.20190304.15
    AB  - Objectives: This study aimed to evaluate the short term follow up for diabetic patients presented with acute STEMI underwent preventive percutaneous coronary intervention. Background: preventive PCI appears to be safe as culprit artery PCI with effective reduction of refractory angina and repeated revascularization in selected patients but no benefit on mortality or recurrent MI. Methods: Our study was a prospective, observational study conducted at multicenter hospitals included 120 diabetic patients admitted with acute STEMI and multivessels CAD at National Heart Institute, Menofia university hospital, police academy center and some private hospitals patients from June 2017 to august 2018, group (A) Consisted of 70 diabetic patients with acute STEMI undergone preventive PCI in whom PCI will be done for culprit & non culprit lesions, group (B) Consisted of 50 diabetic patients with acute STEMI undergone PCI for culprit lesion only. Results: The total revascularization group were significantly less suffering from refractory angina 5 (7.1%) vs 15 (30.0%), p= <0.001 and less re-hospitalized for cardiac causes 14 (20.0%) vs 22 (44.0%), p= 0.005, cardiac mortality was 2 patients 0 (0.0%) vs 2 (4%) p= 0.092. Conclusion: The preventive PCI appears to be safe as culprit artery PCI with effective reduction of refractory angina and repeated revascularization but no benefit on mortality or recurrent MI in selected hemodynamically stable STEMI diabetic patients with multivessel disease.
    VL  - 3
    IS  - 4
    ER  - 

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Author Information
  • Cardiology Department, National Heart Institute, Cairo, Egypt

  • Cardiology Department, Police Academy Center, Cairo, Egypt

  • Cardiology Department, Faculty of Medicine, Menofia Unversity, Al Minufya, Egypt

  • Cardiology Department, Faculty of Medicine, Menofia Unversity, Al Minufya, Egypt

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