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A Pilot Study on the Effectiveness of a Novel Herbal Patch for the Treatment of Plantar Fasciitis

Received: 1 February 2017    Accepted: 18 March 2017    Published: 13 April 2017
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Abstract

The study was to evaluate the safety and anti-inflammatory effects of a herbal patch. The formula of the herbal patch included three herbs Flos Carthami (紅), Radix Dipsaci (續斷), Rhizoma Rhei (大黃) and Borneolum Syntheticum (冰片). 10 subjects suffering from chronic heel pain were recruited. The herbal patch was applied to the heel for 6 weeks. The Pain score Visual Analogue Scale (VAS) and Foot Function Index (FFI) questionnaires were conducted to measure pain and disability. Blood was taken to measure the inflammatory cytokines (IL-8 and hs-CRP). All the assessments were processed on before and after the treatment intervention. After treatment, the pain score and foot function index were remarkably improved. Inflammation Cytokine IL-8 was decreased. The novel herbal patch used in this pilot study had laboratory evidences of anti-inflammation and pro-angiogenesis. The primary results indicated that the study herbal patch is safe and can be an alternative to treatment in plantar fasciitis. With its mildly penetrative property, it could be a suitable additional tool for patients’ self-care.

Published in International Journal of Chinese Medicine (Volume 1, Issue 2)
DOI 10.11648/j.ijcm.20170102.15
Page(s) 70-76
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Plantar Fasciitis, Herbal Patch, Anti-inflammatory Effects

References
[1] Sorrentino F, Iovane A, Vetro A, et al. Role of high resolution ultrasound in guiding treatment of idiopathic plantar fasciitis with minimally invasive techniques. Radiol Med 2008; 113: 486–495.
[2] Weil Jr. L, Glover JP, Weil Sr. L. A new minimally invasive technique for treating plantar fasciosis using bipolar radiofrequency: a prospective analysis. Foot & Ankle Specialist 2008; 1: 13-8.
[3] Elly Budiman-Mak, Kendon J. Conrad and Kathryn E. Roach. The Foot Function Index: A Measure of Foot Pain and Disability. J Clin Epidemiol 1991, 44 (6): 561-570.
[4] Elly Budiman-Mak, Kendon J Conrad, Jessica Mazza and Rodney M Stuck. A review of the foot function index and the foot function index-revised. Journal of Foot and Ankle Research 2013, 6: 5.
[5] Shih-Huey Wu, Huey-Wen Liang, Wen-Hsuan Hou. Reliability and Validity of the Taiwan Chinese Version of the Foot Function Index. J Formos Med Assoc 2008, 107 (2): 111-118.
[6] Schon LC. 1993. Plantar fasciitis/heel pain. In Pfeffer GB, Frey CC, Anderson RB, et al., editors. Current practice in foot and ankle surgery, Vol. 1. New York: McGraw-Hill; pp 243–261.
[7] Davis PF, Severud E, Baxter DE. 1994. Painful heel syndrome: results of non-operative treatment. Foot Ankle Int 15: 531–535.
[8] Ogden JA, Alvarez R, Levitt R, et al. 2001. Shock wave therapy for chronic proximal plantar fasciitis. Clin Orthop 387: 47–59.
[9] Young CC, Rutherford DS, Niedfeldt MW. Treatment of plantar fasciitis. Am Fam Physician 2001; 63 (3). 467-74, 477-8.
[10] Rompe JD. Plantar fasciopathy. Sports Med Arthrosc 2009; 17 (2): 100–4.
[11] Yu JS (2000) Pathologic and post-operative conditions of the plantar fascia: review of MR imaging appearances. Skeletal Radiol 29: 491–501.
[12] Homey, B.; Steinhoff, M.; Ruzicka, T.; Leung, D. Y. Cytokines and chemokines orchestra atopic skin inflammation. J. Allergy Clin. Immunol. 2006, 118, 178–189.
[13] Wong, C. K.; Lam, C. W. Clinical applications of cytokine assays. Adv. Clin. Chem. 2003, 37, 1–46.
[14] Marco Baggiolini, Ian Clark-Lcwis. Interleukin-8, a chemotactic and inflammatory cytokine. FEBS Lett. 1992; 307 (1): 97-101.
Cite This Article
  • APA Style

    Lung-fung Tse, Hi-shan Cheng, Leung-kim Hung, Ellie Pang, King-fai Cheng, et al. (2017). A Pilot Study on the Effectiveness of a Novel Herbal Patch for the Treatment of Plantar Fasciitis. International Journal of Chinese Medicine, 1(2), 70-76. https://doi.org/10.11648/j.ijcm.20170102.15

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    ACS Style

    Lung-fung Tse; Hi-shan Cheng; Leung-kim Hung; Ellie Pang; King-fai Cheng, et al. A Pilot Study on the Effectiveness of a Novel Herbal Patch for the Treatment of Plantar Fasciitis. Int. J. Chin. Med. 2017, 1(2), 70-76. doi: 10.11648/j.ijcm.20170102.15

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    AMA Style

    Lung-fung Tse, Hi-shan Cheng, Leung-kim Hung, Ellie Pang, King-fai Cheng, et al. A Pilot Study on the Effectiveness of a Novel Herbal Patch for the Treatment of Plantar Fasciitis. Int J Chin Med. 2017;1(2):70-76. doi: 10.11648/j.ijcm.20170102.15

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  • @article{10.11648/j.ijcm.20170102.15,
      author = {Lung-fung Tse and Hi-shan Cheng and Leung-kim Hung and Ellie Pang and King-fai Cheng and Wing-sum Siu and Jing-zhou Chen and Xue-lin Zhou and Chak-hei Fung and Ping-chung Leung},
      title = {A Pilot Study on the Effectiveness of a Novel Herbal Patch for the Treatment of Plantar Fasciitis},
      journal = {International Journal of Chinese Medicine},
      volume = {1},
      number = {2},
      pages = {70-76},
      doi = {10.11648/j.ijcm.20170102.15},
      url = {https://doi.org/10.11648/j.ijcm.20170102.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20170102.15},
      abstract = {The study was to evaluate the safety and anti-inflammatory effects of a herbal patch. The formula of the herbal patch included three herbs Flos Carthami (紅), Radix Dipsaci (續斷), Rhizoma Rhei (大黃) and Borneolum Syntheticum (冰片). 10 subjects suffering from chronic heel pain were recruited. The herbal patch was applied to the heel for 6 weeks. The Pain score Visual Analogue Scale (VAS) and Foot Function Index (FFI) questionnaires were conducted to measure pain and disability. Blood was taken to measure the inflammatory cytokines (IL-8 and hs-CRP). All the assessments were processed on before and after the treatment intervention. After treatment, the pain score and foot function index were remarkably improved. Inflammation Cytokine IL-8 was decreased. The novel herbal patch used in this pilot study had laboratory evidences of anti-inflammation and pro-angiogenesis. The primary results indicated that the study herbal patch is safe and can be an alternative to treatment in plantar fasciitis. With its mildly penetrative property, it could be a suitable additional tool for patients’ self-care.},
     year = {2017}
    }
    

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    AU  - Lung-fung Tse
    AU  - Hi-shan Cheng
    AU  - Leung-kim Hung
    AU  - Ellie Pang
    AU  - King-fai Cheng
    AU  - Wing-sum Siu
    AU  - Jing-zhou Chen
    AU  - Xue-lin Zhou
    AU  - Chak-hei Fung
    AU  - Ping-chung Leung
    Y1  - 2017/04/13
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijcm.20170102.15
    DO  - 10.11648/j.ijcm.20170102.15
    T2  - International Journal of Chinese Medicine
    JF  - International Journal of Chinese Medicine
    JO  - International Journal of Chinese Medicine
    SP  - 70
    EP  - 76
    PB  - Science Publishing Group
    SN  - 2578-9473
    UR  - https://doi.org/10.11648/j.ijcm.20170102.15
    AB  - The study was to evaluate the safety and anti-inflammatory effects of a herbal patch. The formula of the herbal patch included three herbs Flos Carthami (紅), Radix Dipsaci (續斷), Rhizoma Rhei (大黃) and Borneolum Syntheticum (冰片). 10 subjects suffering from chronic heel pain were recruited. The herbal patch was applied to the heel for 6 weeks. The Pain score Visual Analogue Scale (VAS) and Foot Function Index (FFI) questionnaires were conducted to measure pain and disability. Blood was taken to measure the inflammatory cytokines (IL-8 and hs-CRP). All the assessments were processed on before and after the treatment intervention. After treatment, the pain score and foot function index were remarkably improved. Inflammation Cytokine IL-8 was decreased. The novel herbal patch used in this pilot study had laboratory evidences of anti-inflammation and pro-angiogenesis. The primary results indicated that the study herbal patch is safe and can be an alternative to treatment in plantar fasciitis. With its mildly penetrative property, it could be a suitable additional tool for patients’ self-care.
    VL  - 1
    IS  - 2
    ER  - 

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Author Information
  • Department of Orthopaedics & Traumatology, Prince of Wales Hospital, Hong Kong, China

  • Department of Orthopaedics & Traumatology, Prince of Wales Hospital, Hong Kong, China

  • Department of Orthopaedics & Traumatology, Prince of Wales Hospital, Hong Kong, China; Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong (CUHK), Hong Kong, China

  • Institute of Chinese Medicine, CUHK, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, CUHK, Hong Kong, China

  • Institute of Chinese Medicine, CUHK, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, CUHK, Hong Kong, China

  • Institute of Chinese Medicine, CUHK, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, CUHK, Hong Kong, China

  • Department of Orthopaedics & Traumatology, The Chinese University of Hong Kong (CUHK), Hong Kong, China

  • Institute of Chinese Medicine, CUHK, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, CUHK, Hong Kong, China

  • Institute of Chinese Medicine, CUHK, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, CUHK, Hong Kong, China

  • Institute of Chinese Medicine, CUHK, Hong Kong, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, CUHK, Hong Kong, China

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