Calyx Juice of <i>Hibiscus sabdariffa Linn</i> (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs

Franklin Nyenty Tabe; Nicolas Njintang Yanou; Armel Hervé Nwabo Kamdje; Aurélie-Solange Agume Ntso

doi:doi:10.11648/j.jdmp.20150104.12

| Peer-Reviewed

Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Hervé Nwabo Kamdje, Aurélie-Solange Agume Ntso

Published in Journal of Diseases and Medicinal Plants (Volume 1, Issue 4)

Received: 25 August 2015 Accepted: 3 September 2015 Published: 9 September 2015

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

More than three decades after its outbreak, the Acquired Immune Deficiency Syndrome (AIDS) remains a great mystery because there is neither an existing vaccine against its causative agent (the human immune deficiency virus) nor a cure against it. Worst of all is the popular attention that is tuned to the AIDS virus, ignoring oxidative stress which is the major cause of mortality in HIV/AIDS as in many other chronic diseases. Antiretroviral drugs introduced in 1996 have been shown to increase oxidative stress among other drug-related complications. With these backdrops, an antioxidant therapy is necessary to accompany antiretroviral treatment without which its beneficial effects are null. The present review aims to discuss the role of Calyx juice of Hibiscus sabdariffa Linn (Malvaceae) as a possible therapeutic supplement to antiretroviral drugs.

Published in	Journal of Diseases and Medicinal Plants (Volume 1, Issue 4)
DOI	10.11648/j.jdmp.20150104.12
Page(s)	59-67
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Oxidative Stress, Antioxidants, Hibiscus sabdariffa Linn

References

[1]	Esra B., Umit M. S., Cansin S., Serpil E. and Omer K. 2012. Oxidative stress and antioxidant defense. WAO Journal 5:9-19.
[2]	Isaac K. Q. 2012. Oxidative stress in human health and disease, insight and control of infectious disease in global scenario, DR. Roy Priti (Ed.), ISBN: 978-953-51-0319-6, In Tech, Available from: http://www.intechopen.com/books/insight-and-control-of-infectious-disease-in-global-scenario/oxidative-stress-in-health-and-disease.
[3]	Gora D., Praveen S., Shiv G. (July-Sept 2012). Oxidative stress-induced response of some endogenous antioxidants in schizophrenia. Indian Journal of Clinical Biochemistry 27(3):278-283. DOI: 10.1007/s12291-012-0193-z.
[4]	Xuejuan Y., Jun C., Chunxiao Z., Hua C., and Youbin L. 2012. Evaluation of antioxidant activity of fermented soybean meal extract. African Journal of pharmacy and Pharmacology [online] 6 (24):1774-1781. Available from: http://www.academicjournals.org/AJPP. DOI: 1O.5897/AJPP12.392.
[5]	Zhang Y., Dawson V. L., Dawson T. M. 2000. Oxidative stress and genetics in the pathogenesis of Parkinson’s disease. Neurobiol Dis 7:240-250.
[6]	Vishwanath M. S. Introduction to clinical nutrition.2nd ed. [Online]. New York: Marcel Dekker, Inc.; 2003. Available from: http://www.dekker.com.
[7]	Munmee D., Bishnu P. S., Giasuddin A., Cakkalur B. N., Monjoy K. C. 2012. In vitro anti oxidant activity and total phenolic content of Dillenia indica and Garcinia penducalata, commonly used fruits in Assamese cuisine. Free Radicals and Antioxidants 2(2). DOI: 10.5530/ax.2012.2.6.
[8]	Abheri D. S., Anisur R. M., and Ghosh A. K. 2010. Free radicals and their role in different clinical conditions: An overview. International Journal of Pharmaceutical Sciences and Research 1(3):185-192.
[9]	Noori S. 2012. An overview of oxidative stress and antioxidant defensive system. 1:413. DOI: 10.4172/scientificreports.413.
[10]	Amit K., Priyadarsini K. I. 2011. Free radicals, oxidative stress and importance of antioxidants in human health. Journal of Medical Allied Sciences [online] 1(2):53-60. Available from: www.jmas.in. [Accessed 31st March 2013]
[11]	Lien A P. H., Hua H., Chuong P. H. 2008. Free radicals, antioxidants in disease and health. Journal of Biomedical Sciences [online] 4(2):89-96.available from: http://www.ijbs.org. [Accessed 1st November 2013]
[12]	Upma G., Anju J., Parul S., Sarita B., Rajiv G., Arvind S. (April-June 2012). Free radical status in retinopathy of prematurity. Indian Journal of Clinical Biochemistry 27(2):196-199.
[13]	Gerhard Krauss. Biochemistry of signal transduction and regulation.3rd ed. Wiley-VCH Verlag. GmbH and Co. KGaA, Weinheim; 2003.
[14]	Manzoor A., Nida S., Tariq M., Naheed B., Shamshad A. (Oct-Dec 2012). Evaluation of oxidative stress and DNA damage in benign prostatic hyperplasia patients and comparison with controls. Indian Journal of Clinical Biochemistry 27(4):385-388.
[15]	Lizette G. D. V., Rosario G. H., Jorge P. A. 2013. Oxidative stress associated to disease progression and toxicity during antiretroviral therapy in Human Immunodeficiency Virus infection. Journal of Virology and Microbiology [online] 2013:15. Available from: http://www.ibimapublishing.com/journals/JVM/jvm.html. DOI: 10.5171/2013.279685. [Accessed14th February 2014]
[16]	Bo J., Alok R. K., Lynette K. R., Valeria Y. H., James H. Z., et al. 2010 October. Antiretroviral induce endothelial dysfunction via an oxidant-dependent pathway and promote neointimal hyperplasia. Toxicological Science 117(2): 524-536.
[17]	Anthony H. K., Ashok A. 2011. Oxidants and antioxidants in the pathogenesis of HIV/AIDS. The Open Reproductive Science Journal 3: 154-161. DOI: 10.1186/1742-6405-3-19. [Accessed 7th October 2013]
[18]	Seyed A. A., Seyedeh F. M., and Ebrahim B. 2012. Antioxidants: A few key points. Annals of Biological Research [online] 3(8):3968-3977. Available from: http//www.scholarsresearchlibrary.com. [Accessed 14th June 2014]
[19]	Saikat S., Raja C., Sridhar C., Reddy Y. S. R., Biplab D. 2010. Free radicals, antioxidants, diseases and phytomedicines: Current status and future prospect. International Journal of Pharmaceutical Sciences Review and Research [online] 3(21):091-100. Available from: http//www.globalresearchonline.net
[20]	Erin E. B. and Julia L. B. 2009. Antioxidant activity of sulfur and selenium: A review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms. Cell Biochemistry and Biophysics 55:1-23. DOI: 10.1007/s12013-009-9054-7
[21]	Krishna P. B., Debasish B. and Govindasamy M. 2013. Synthetic glutathione peroxidase mimics: Effect of nucleophilicity of the aryl thiol cofactor on the antioxidant activity. Indian Journal of Chemistry 52:1019-1025.
[22]	Maria L. C. 2010. An update of vitamin E, tocopherol and tocotrienol- perspectives: A review. Molecules [online] 15:2103-2113. Available from: http//www.mdpi.com/jornal/molecules. DOI: 10.3390/molecules.15042103. [Accessed11th August 2014]
[23]	Aysun H. 2009. An overview of ascorbic acid biochemistry. Journal of Faculty of Pharmacy, Ankara 38(3):233-255.
[24]	Vittorio C., Marzia P., Carolin C., Raffaella C., Fabio D. D., Giovanni P., et al. Phenolics in aging and neurodegenerative disorders. In: Cesar G. Fraga (Ed.). Plant phenolics and human health. Hoboken, New Jersey: John Wiley and sons Inc.:2010.p.427-444.
[25]	James H. D. 2012. Phytochemicals: Extraction Methods, Basic Structures and Mode of Action as Potential Chemotherapeutic Agents, Phytochemicals-A Global Perspective of Their Role in Nutrition and Health, Dr. Venketshwer Rao (Ed.), ISBN: 978-953-51-0296-0, InTech, Available from: http//www.intecopen.com/books/phytochemicals-a-global-perspective-of-their-role-in-nutrition-and-health/phytochemicals-extraction-methods-basic-structures-and-mode-of-action-as-potential-chemotherapeutic-agents.
[26]	Satyanand T., Gunjan S., Anamika S., Gulshan A. 2010. Phytochemicals as candidate therapeutics: An overview. International Journal of Pharmaceutical Sciences Review and Research [online] 3(1):53-55. Available from: http//www.globalresearchonline.net. [Accessed 11th August 2014]
[27]	Siwang Y., Ka L. C., Wenge L., and Ah-ng K. Plant phenolic compounds: Modulation of cytoprotective enzymes and Nrf2/ARE signaling. In: Cesar G. Fraga (ed.) Plant phenolics and human health. Hoboken, New Jersey: John Wiley and sons Inc.; 2010. P. 402-409.
[28]	Sanda V. K. B. B., Maja B. S. and Marija B. 2012. Plant polyphenols as antioxidants Influencing the Human Health, Phytochemicals as Nutraceuticals-Global Approaches to Their Role in Nutrition and Health, Dr. Venketeshwer Rao (Ed.), ISBN:978-953-51-0203-8, InTech, Available from: http//www.intechopen.com/books/phytochemicals-as-nutraceuticals-global-approaches-to-their-role-in-nutrition-and-health/plant-polyphenols-as-antioxidants-influencing-the-human-health.
[29]	Tapas A. R., Sakarkar D. M. and Kakde R. B. 2008. Flavonoids as nutraceuticals: A review. Tropical Journal of Pharmaceutical Research [online] 7(3):1089-1099. Available from: http//www.tjpr.org.
[30]	Zuzana K. 2011. Toxicological aspects of the use of phenolic compounds in disease prevention. Interdisciplinary Toxicology [online] 4(4):173-183. Available from: http//www.intertox.sav.sk and http//www.versita.com/science/medicine/it/ DOI: 10.2478/v10102-011-0027-5. [Accessed 11th August 2014]
[31]	Evelyn B. R., Maxima E. F., Delia B. R. A. and Jaime A. F. 2006. Phytochemicals and functional foods. Current situation and prospect for developing countries. Segurança Alímentar e Nutricional, Campinas 13(1):1-22
[32]	Indu B. J. and Alan C. Dietary flavonoids and phenolic compounds. In: Cesar G. Fraga(Ed.). Plant phenolics and human health. Hoboken, New Jersey: John Wiley and sons Inc.:2010.p.1-39.
[33]	Cesar G. F., Gulcin S. C., and Monica G. Biochemical actions of plant phenolics compounds: Thermodynamic and kinetic aspects. In: Cesar G. Fraga (ed.) Plant phenolics and human health. Hoboken, New Jersey: John Wiley and sons Inc.; 2010. P. 91-103.
[34]	Harleen K. S., Bimlesh K., Sunil P., Prashant T., Manoj S., Pardeep S. 2011. A review of phytochemistry and pharmacology of flavonoids. International Pharmaceutica Sciencia [online] 1(1):25-41. Available from: http//www.ipharmsciencia.com.
[35]	Mohamed A. H. 2011. A convenient mechanism for the free radical scavenging activity of resveratrol. International Journal of Phytomedicine [online] 3:459-469. Available from: http//www.arjournals.org/index.php/ijpm/index. [Accessed 14th June 2014]
[36]	Ajit B. P. and Asha S. J. 2013. Flavonoids, an antioxidant: A review. International Journal of Pharmaceutical and Biological Sciences Research and Development [online] 1(2):07-20. Available from: http://www.ijpbsrd.com. [Accessed 14th June 2014]
[37]	Elżbieta S., Ewa C., Kinga T. 2008. The sources of natural antioxidants. Acta Sci. Pol., Technol. Aliment. 7(1):5-17.
[38]	Dilip K. P. and Preeti V. 2013. Flavonoids: A powerful and abundant source of antioxidants. International Journal of Pharmacy and Pharmaceutical Sciences 5(3):95-98
[39]	Augusti K. T., Regi J., Sajitha G. R., Paul A. (Jan-Mar 2012). A rethinking on the benefits and drawbacks of common antioxidants and a proposal to look for the antioxidants in allium products as ideal agents: A review. Indian Journal of Clinical Biochemistry 27(1): 6-20.
[40]	Mady C., Manuel D., Mama S., Augustin N., Max R., Oumar S. 2009. Le bissap (Hibiscus sabdariffa L): composition et principales utilisations. Fruits [online] 64(3): 179-193. Available from: http://www.fruits-journal.org or http://dx.doi.org/10.1051/fruits/2009013. [Accessed 7th October 2013]
[41]	Germaine Y., Jean-Bosco T., Clergé T. 2009. Protein, carbohydrate, fat and energy content of “Ready-to-eat-Foods” in Cameroonian Sahel’s Region.Journal of Food Technology 7(1):1-4.
[42]	Claudia S. G., Fidel T. V. B., Anna E. O. R., José A. G.B. 2012. Antioxidant properties and color of Hibiscus sabdariffa extracts. Ciencia e Investigación Agraria [online] 39(1):79-90. Available from: www.rcia.uc.cl. [Accessed 7th October 2013]
[43]	Mahadevan N., Shivali and Pradeep K. 2009. Hibiscus sabdariffa Linn- An overview. Natural Product Radiance 8(1):77-83.
[44]	Bahaeldeen B. M., Abdelatif A. S., and Abdel hafiz A. D. 2012. Roselle (Hibiscus sabdariffa L.) in Sudan, cultivation and their uses. Bulletin of Environment, Pharmacology and Life Sciences [online] 1(6):48-54. Available from: www.bepls.com. [Accessed 16th February 2014]
[45]	Amin I., Emmy H. K., Halimatul S. M. N. 2008. Roselle (Hibiscus sabdariffa L.) seeds- nutritional composition, protein quality and health benefits. Food 2(1):1-16.
[46]	Ijeomah A. U., Ugwuona F. U. and Abdullahi H. 2012. Phytochemical composition and antioxidant properties of Hibiscus sabdariffa and Moringa oleifera. Nigerian Journal of Agriculture, Food and Environment 8(1):10-16.
[47]	Alaa G. A-H. 2012. Antioxidant and anti bacterial activities of Hibiscus sabdariffa L. extracts. African Journal of Food Science [online] 6(21):506-511. Available from: http://www.academicjournals.org/AJFSDOI: 10.5897/AJFS12.099. [Accessed 7th October 2013]
[48]	Norhaizan M-E., Fong S. H., Amin I., Chew L. Y. 2010. Antioxidant activity in different parts of the Roselle (Hibiscus sabdariffa L) extracts and potential exploitation of the seeds. Food Chemistry [online] 122(2010): 1055-1060. Available from: http://www.elsevier.com/locate/foodchem. [Accessed 7th October 2013]
[49]	Mowuogwu F. O., George B. O. 2008. Comparative antioxidant activity of Hibiscussabdariffaand ascorbic acid on ferrous sulfate-induced oxidative stress in Clarian gariepinus. East Central African Journal of Pharmaceutical Sciences 11(2008): 39-42.
[50]	Prashant T., Bimlesh K., Mandeep K., Gurpreet K., Harleen K. 2011. Phytochemical screening and extraction: A review. International Pharmaceutica Sciencia [online] 1(1):98-106. Available from: http//www.ipharmsciencia.com. [Accessed 11th August 2014]
[51]	Bolade M. K., Oluwalana I. B., and Ojo O. 2009. Commercial practice of Roselle (Hibiscus sabdariffa L.). Beverage production: Optimization of hot water extraction and sweetness level. World Journal of Agricultural Sciences 5(1):126-131.

Cite This Article

Plain Text BibTeX RIS

APA Style

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Hervé Nwabo Kamdje, Aurélie-Solange Agume Ntso. (2015). Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs. Journal of Diseases and Medicinal Plants, 1(4), 59-67. https://doi.org/10.11648/j.jdmp.20150104.12

Copy | Download

ACS Style

Franklin Nyenty Tabe; Nicolas Njintang Yanou; Armel Hervé Nwabo Kamdje; Aurélie-Solange Agume Ntso. Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs. J. Dis. Med. Plants 2015, 1(4), 59-67. doi: 10.11648/j.jdmp.20150104.12

Copy | Download

AMA Style

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Hervé Nwabo Kamdje, Aurélie-Solange Agume Ntso. Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs. J Dis Med Plants. 2015;1(4):59-67. doi: 10.11648/j.jdmp.20150104.12

Copy | Download

@article{10.11648/j.jdmp.20150104.12,
  author = {Franklin Nyenty Tabe and Nicolas Njintang Yanou and Armel Hervé Nwabo Kamdje and Aurélie-Solange Agume Ntso},
  title = {Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {1},
  number = {4},
  pages = {59-67},
  doi = {10.11648/j.jdmp.20150104.12},
  url = {https://doi.org/10.11648/j.jdmp.20150104.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20150104.12},
  abstract = {More than three decades after its outbreak, the Acquired Immune Deficiency Syndrome (AIDS) remains a great mystery because there is neither an existing vaccine against its causative agent (the human immune deficiency virus) nor a cure against it. Worst of all is the popular attention that is tuned to the AIDS virus, ignoring oxidative stress which is the major cause of mortality in HIV/AIDS as in many other chronic diseases. Antiretroviral drugs introduced in 1996 have been shown to increase oxidative stress among other drug-related complications. With these backdrops, an antioxidant therapy is necessary to accompany antiretroviral treatment without which its beneficial effects are null. The present review aims to discuss the role of Calyx juice of Hibiscus sabdariffa Linn (Malvaceae) as a possible therapeutic supplement to antiretroviral drugs.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs
AU  - Franklin Nyenty Tabe
AU  - Nicolas Njintang Yanou
AU  - Armel Hervé Nwabo Kamdje
AU  - Aurélie-Solange Agume Ntso
Y1  - 2015/09/09
PY  - 2015
N1  - https://doi.org/10.11648/j.jdmp.20150104.12
DO  - 10.11648/j.jdmp.20150104.12
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 59
EP  - 67
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20150104.12
AB  - More than three decades after its outbreak, the Acquired Immune Deficiency Syndrome (AIDS) remains a great mystery because there is neither an existing vaccine against its causative agent (the human immune deficiency virus) nor a cure against it. Worst of all is the popular attention that is tuned to the AIDS virus, ignoring oxidative stress which is the major cause of mortality in HIV/AIDS as in many other chronic diseases. Antiretroviral drugs introduced in 1996 have been shown to increase oxidative stress among other drug-related complications. With these backdrops, an antioxidant therapy is necessary to accompany antiretroviral treatment without which its beneficial effects are null. The present review aims to discuss the role of Calyx juice of Hibiscus sabdariffa Linn (Malvaceae) as a possible therapeutic supplement to antiretroviral drugs.
VL  - 1
IS  - 4
ER  -

Copy | Download

Author Information

Franklin Nyenty Tabe

Department of Biomedical Science, Faculty of Science, University of Ngaoundere, Adamawa Region, Cameroon
Nicolas Njintang Yanou

Department of Biomedical Science, Faculty of Science, University of Ngaoundere, Adamawa Region, Cameroon
Armel Hervé Nwabo Kamdje

Department of Biomedical Science, Faculty of Science, University of Ngaoundere, Adamawa Region, Cameroon
Aurélie-Solange Agume Ntso

Department of Food Engineering and Quality Control, University Institute of Technology, Ngaoundere, Adamawa Region, Cameroon

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Hervé Nwabo Kamdje, Aurélie-Solange Agume Ntso. (2015). Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs. Journal of Diseases and Medicinal Plants, 1(4), 59-67. https://doi.org/10.11648/j.jdmp.20150104.12

Copy | Download

ACS Style

Franklin Nyenty Tabe; Nicolas Njintang Yanou; Armel Hervé Nwabo Kamdje; Aurélie-Solange Agume Ntso. Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs. J. Dis. Med. Plants 2015, 1(4), 59-67. doi: 10.11648/j.jdmp.20150104.12

Copy | Download

AMA Style

Franklin Nyenty Tabe, Nicolas Njintang Yanou, Armel Hervé Nwabo Kamdje, Aurélie-Solange Agume Ntso. Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs. J Dis Med Plants. 2015;1(4):59-67. doi: 10.11648/j.jdmp.20150104.12

Copy | Download

@article{10.11648/j.jdmp.20150104.12,
  author = {Franklin Nyenty Tabe and Nicolas Njintang Yanou and Armel Hervé Nwabo Kamdje and Aurélie-Solange Agume Ntso},
  title = {Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {1},
  number = {4},
  pages = {59-67},
  doi = {10.11648/j.jdmp.20150104.12},
  url = {https://doi.org/10.11648/j.jdmp.20150104.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20150104.12},
  abstract = {More than three decades after its outbreak, the Acquired Immune Deficiency Syndrome (AIDS) remains a great mystery because there is neither an existing vaccine against its causative agent (the human immune deficiency virus) nor a cure against it. Worst of all is the popular attention that is tuned to the AIDS virus, ignoring oxidative stress which is the major cause of mortality in HIV/AIDS as in many other chronic diseases. Antiretroviral drugs introduced in 1996 have been shown to increase oxidative stress among other drug-related complications. With these backdrops, an antioxidant therapy is necessary to accompany antiretroviral treatment without which its beneficial effects are null. The present review aims to discuss the role of Calyx juice of Hibiscus sabdariffa Linn (Malvaceae) as a possible therapeutic supplement to antiretroviral drugs.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Calyx Juice of Hibiscus sabdariffa Linn (Malvaceae): A Possible Therapeutic Supplement to Antiretroviral Drugs
AU  - Franklin Nyenty Tabe
AU  - Nicolas Njintang Yanou
AU  - Armel Hervé Nwabo Kamdje
AU  - Aurélie-Solange Agume Ntso
Y1  - 2015/09/09
PY  - 2015
N1  - https://doi.org/10.11648/j.jdmp.20150104.12
DO  - 10.11648/j.jdmp.20150104.12
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 59
EP  - 67
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20150104.12
AB  - More than three decades after its outbreak, the Acquired Immune Deficiency Syndrome (AIDS) remains a great mystery because there is neither an existing vaccine against its causative agent (the human immune deficiency virus) nor a cure against it. Worst of all is the popular attention that is tuned to the AIDS virus, ignoring oxidative stress which is the major cause of mortality in HIV/AIDS as in many other chronic diseases. Antiretroviral drugs introduced in 1996 have been shown to increase oxidative stress among other drug-related complications. With these backdrops, an antioxidant therapy is necessary to accompany antiretroviral treatment without which its beneficial effects are null. The present review aims to discuss the role of Calyx juice of Hibiscus sabdariffa Linn (Malvaceae) as a possible therapeutic supplement to antiretroviral drugs.
VL  - 1
IS  - 4
ER  -

Copy | Download