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Adherence to Antiretroviral Therapy and Associated Factors Among Adult ARV Users in Arba Minch Hospital, Southern Ethiopia

Received: 14 June 2017    Accepted: 28 June 2017    Published: 21 July 2017
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Abstract

The provision of Antiretroviral Therapy (ART), HIV/AIDS is becoming a chronic manageable disease; therefore to manage chronic disease, adherence to HIV medication is very important but a variety of other factors may complicate ART adherence that needs devotion from patients, provisions of health services and health care professionals, and having social support from the society. The purpose of this study was to determine the level of adherence to ART and associated factors among adult antiretroviral drugs (ARV) users. A cross sectional study was carried out at Arba Minch Hospital from March 5 to May 5, 2015. One month patients’ self-report and pharmacy refill records were used to assess adherence. Data were collected by a standard questionnaire after pre-tested and data abstraction format. The collected data were entered in to Epi-Info and it was exported in to SPSS for data analysis. Multiple logistic regressions analysis was applied and statistical significance test was declared at P-value <0.05 and OR with 95% CI. Based on patients’ self-report dose adherence, among the 428 study participants, the magnitude of adherence to ART in a month before interview was 77.10%. Multivariable analysis showed that, adherence was positively associated with sex (male) (AOR=3.03, CI (1.69-5.42)), free from substance uses (AOR=3.49, CI (1.80-6.77)), absence of side effect of drugs (AOR =2.61, CI (1.19-5.73)), ART schedule fit to daily routines (AOR= 2.93, CI (1.24-6.91)) and feeling comfort on taking ART drug in front of others (AOR=3.32, CI (1.54-7.16)). The ART adherence rate of this study was relatively low compared with WHO standard and others study in Ethiopia. Sex, feeling comfort on taking the ART drugs, ART schedule fit to daily routines, substance use and drug side effects were strong predictors of adherence.

Published in Central African Journal of Public Health (Volume 3, Issue 2)
DOI 10.11648/j.cajph.20170302.12
Page(s) 19-26
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

ART, Adherence, HIV Patients, Southern Ethiopia

References
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[6] Ethiopian Ministry of Health: Access of Antiretroviral drugs and treatment program in Ethiopia. Addis Ababa (Ethiopia): Ministry of Health, 2014.
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[11] Braitstein P, Brinkhof M, Dabis F, Schechter M, Boull A, et al. Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: Comparison between low-income and high-income countries. Lancet. 2006; 367:817-24.
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[13] Kiday H, Belachew E, Mussie A, Girmatsion F. Factors associated with adherence of highly active antiretroviral therapy among adult HIV/AIDS patients in Mekelle Hospital Northern Ethiopia. Science Journal of Public Health. 2014; 2(4):367-72.
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  • APA Style

    Nuredin Nassir Azmach. (2017). Adherence to Antiretroviral Therapy and Associated Factors Among Adult ARV Users in Arba Minch Hospital, Southern Ethiopia. Central African Journal of Public Health, 3(2), 19-26. https://doi.org/10.11648/j.cajph.20170302.12

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    ACS Style

    Nuredin Nassir Azmach. Adherence to Antiretroviral Therapy and Associated Factors Among Adult ARV Users in Arba Minch Hospital, Southern Ethiopia. Cent. Afr. J. Public Health 2017, 3(2), 19-26. doi: 10.11648/j.cajph.20170302.12

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    AMA Style

    Nuredin Nassir Azmach. Adherence to Antiretroviral Therapy and Associated Factors Among Adult ARV Users in Arba Minch Hospital, Southern Ethiopia. Cent Afr J Public Health. 2017;3(2):19-26. doi: 10.11648/j.cajph.20170302.12

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  • @article{10.11648/j.cajph.20170302.12,
      author = {Nuredin Nassir Azmach},
      title = {Adherence to Antiretroviral Therapy and Associated Factors Among Adult ARV Users in Arba Minch Hospital, Southern Ethiopia},
      journal = {Central African Journal of Public Health},
      volume = {3},
      number = {2},
      pages = {19-26},
      doi = {10.11648/j.cajph.20170302.12},
      url = {https://doi.org/10.11648/j.cajph.20170302.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20170302.12},
      abstract = {The provision of Antiretroviral Therapy (ART), HIV/AIDS is becoming a chronic manageable disease; therefore to manage chronic disease, adherence to HIV medication is very important but a variety of other factors may complicate ART adherence that needs devotion from patients, provisions of health services and health care professionals, and having social support from the society. The purpose of this study was to determine the level of adherence to ART and associated factors among adult antiretroviral drugs (ARV) users. A cross sectional study was carried out at Arba Minch Hospital from March 5 to May 5, 2015. One month patients’ self-report and pharmacy refill records were used to assess adherence. Data were collected by a standard questionnaire after pre-tested and data abstraction format. The collected data were entered in to Epi-Info and it was exported in to SPSS for data analysis. Multiple logistic regressions analysis was applied and statistical significance test was declared at P-value <0.05 and OR with 95% CI. Based on patients’ self-report dose adherence, among the 428 study participants, the magnitude of adherence to ART in a month before interview was 77.10%. Multivariable analysis showed that, adherence was positively associated with sex (male) (AOR=3.03, CI (1.69-5.42)), free from substance uses (AOR=3.49, CI (1.80-6.77)), absence of side effect of drugs (AOR =2.61, CI (1.19-5.73)), ART schedule fit to daily routines (AOR= 2.93, CI (1.24-6.91)) and feeling comfort on taking ART drug in front of others (AOR=3.32, CI (1.54-7.16)). The ART adherence rate of this study was relatively low compared with WHO standard and others study in Ethiopia. Sex, feeling comfort on taking the ART drugs, ART schedule fit to daily routines, substance use and drug side effects were strong predictors of adherence.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Adherence to Antiretroviral Therapy and Associated Factors Among Adult ARV Users in Arba Minch Hospital, Southern Ethiopia
    AU  - Nuredin Nassir Azmach
    Y1  - 2017/07/21
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    VL  - 3
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Author Information
  • Department of Statistics, College of Natural Sciences, Arba Minch University, Arba Minch, Ethiopia

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