Evaluation of Malaria Parasitemia Among HIV/AIDS Individuals Attending the Bamenda Regional Hospital Treatment Center
Central African Journal of Public Health
Volume 5, Issue 2, April 2019, Pages: 65-76
Received: Jan. 12, 2019; Accepted: Feb. 14, 2019; Published: Feb. 28, 2019
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Eyong Clinton Achere, Department of Biomedical Sciences, Faculty of Health Sciences, the University of Bamenda, Bamenda, Cameroon
Kechia Federick Agem, Department of Biomedical Sciences, Faculty of Health Sciences, the University of Bamenda, Bamenda, Cameroon
Tembe Fokunang Estella, Department of Pharmaco-Toxicology & Pharmacokinetics, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon
Tatang Collins Asaah, Department of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon
Wandum Gangdia Carlson, Department of Biomedical Sciences, Faculty of Health Sciences, the University of Bamenda, Bamenda, Cameroon
Agbor Michael Ashu, Department of Dentistry, Faculty of Health Sciences, University of Bangante, Bangante, Cameroon
Mbanya Dora Shu, Department of Biomedical Sciences, Faculty of Health Sciences, the University of Bamenda, Bamenda, Cameroon
Fokunang Charles Ntungwen, Department of Pharmaco-Toxicology & Pharmacokinetics, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon
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Malaria parasitemia and HIV/AIDS coinfection is very common particularly in sub-Saharan Africa where the burden of both infections fall. Therefore, an understanding of how the two infections interact is important for the control of both diseases. In Cameroon some studies have been carried out on the prevalence of malaria parasitemia in HIV with varying results. A high prevalence of malaria parasitemia among these individuals could imply the need for systematic screening and/or treatment of HIV individuals for possible malaria infection hence improving on the care of these individuals. A low prevalence could also imply limiting resources directed towards the diagnosis of malaria in HIV individuals. Objectives: The objective of the study was to determine the prevalence of malaria parasitaemia in HIV/AIDS individuals in Bamenda Regional Hospital (BRH) Treatment Center. Methods: A cross-sectional study was conducted involving 310 HIV-positive individuals attending the BRH HIV/AIDS Treatment Centre during a period of 3 months from 1st of February to April 30th 2018. Participants’ consent was obtained followed by sociodemographic and other useful data via a standardized questionnaire. Capillary blood samples were collected and malaria parasitaemia determined by blood smear microscopy. Results: An overall malaria parasitemia prevalence of 24.5% was observed in this study with mean parasite density of 150 trophozoites/µL. Malaria parasitemia prevalence was significantly higher in HAART naïve (37.5%) individuals than HAART experienced (23.81%) individuals (p<0.05). The differences in level of parasite density in relation to gender and marital status were statistically significant (p<0.05) while that of the various age groups was not significant (p<0.05). Lower CD4 count levels were significantly related to high density malaria parasitemia (p<0.05). Also the percentage of parasite density >400 trophozoites/µL was higher (80%) in those not using cotrimoxazole prophylaxis than those on cotrimoxazole prophylaxis (20%). Hence non- use of cotrimoxazole prophylaxis was significantly associated with high density malaria parasitemia (p<0.05). Conclusions The prevalence of malaria parasitemia in HIV/AIDS individuals was high in the study area and malaria parasitemia prevalence in HAART naïve individuals was significantly higher than in HAART experienced individuals. Also gender, marital status low CD4 count and non use of cotrimoxazole prophylaxis were significantly related to high density malaria parasitemia.
Malaria Parasitemia, HIV/AIDS, HAART, Prevalence
To cite this article
Eyong Clinton Achere, Kechia Federick Agem, Tembe Fokunang Estella, Tatang Collins Asaah, Wandum Gangdia Carlson, Agbor Michael Ashu, Mbanya Dora Shu, Fokunang Charles Ntungwen, Evaluation of Malaria Parasitemia Among HIV/AIDS Individuals Attending the Bamenda Regional Hospital Treatment Center, Central African Journal of Public Health. Vol. 5, No. 2, 2019, pp. 65-76. doi: 10.11648/j.cajph.20190502.12
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