Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea)

Salifou Talassone Bangoura; Abdoulaye Toure; Sidikiba Sidibé; Alioune Camara; Djibril Sylla; Alpha-Kabinet Keita; Mamadou Saliou Sow; Alimou Camara; Mamadou Saliou Kalifa Diallo; Mohamed Cisse

doi:doi:10.11648/j.cajph.20200601.11

Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea)

Salifou Talassone Bangoura, Abdoulaye Toure, Sidikiba Sidibé, Alioune Camara, Djibril Sylla, Alpha-Kabinet Keita, Mamadou Saliou Sow, Alimou Camara, Mamadou Saliou Kalifa Diallo, Mohamed Cisse

Published in Central African Journal of Public Health (Volume 6, Issue 1)

Received: 21 November 2019 Accepted: 17 December 2019 Published: 6 January 2020

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Abstract

Background: In hospitals, antibiotics are one of the most prescribed drug classes. The purpose of this study was to describe the extent and factors associated with the prescription of antibiotics in the Internal Medicine Department of Donka National Hospital. Material and Methods: A cross-sectional study was conducted from July 30, 2018 to January 31, 2019 among prescribers and patients hospitalized or seen on an outpatient basis. Data were collected by direct interview and through patient records. A multivariate logistic regression was performed to identify the factors associated with antibiotic prescribing. Results: Out of a total of 400 consultants, 82 (21%) patients received antibiotic therapy. Beta-lactam antibiotics were the most prescribed antibiotic (45%) and urogenital infections (24.3%) were the most common indication. In univariate analysis, the consultation by a trainee physician [OR = 3.06 (95% CI: 1.56-6)] was associated with a prescription for antibiotics. Students/students [OR = 1.85 (95% CI: 1.01-3.39)], civil servants [OR = 1.82 (95% CI: 1.02-3.26)], patients residing in Conakry [OR = 2.06 (95% CI: 1.08-3.91)], those hospitalized [OR = 3.16 (95% CI: 1.55-6.46)] and those with a fever [OR = 6.49 (95% CI: 3.84-10.96)] were more likely to receive an antibiotic. Only fever [OR adjusted = 4.30 (95% CI: 2.43-7.61)] remained associated with the prescription of antibiotics in multivariate analysis. Conclusion: The results showed that fever was the factor independently associated with the antibiotic prescription. In a country where malaria is the main cause of fever, the results suggest the need for training health care workers in antibiotic prescribing.

Published in	Central African Journal of Public Health (Volume 6, Issue 1)
DOI	10.11648/j.cajph.20200601.11
Page(s)	1-4
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antibiotic, Frequency, Associated Factors

References

[1]	Bevilacqua S, Boschetti E, Lozniewski A and al. Policy proper use of antibiotics: the example of Nancy University Hospital. Med Mal Infect 2007; 37: 32-33.
[2]	Roger PM, Labate C, Brofferio P and al. Prospective evaluation of antibiotic associations by the reference infectious disease specialist of a hospital center. Med Mal Infect 2008; 38: 159.
[3]	Sow MS, Camara A, Fortes Déguénonvo L and al. Evaluation of the prescription of antibiotics in the lower respiratory tract infections in adults at the University Hospital of Conakry in Guinea. Rev. CAMES-Série A 2012; 13: 239-243.
[4]	Huibers L, Moth G, Christensen MB and Vedsted P. Antibiotic prescribing patterns in out-of-hours primary care: A population-based descriptive study. Scandinavian Journal of Primary Health Care 2014; 32: 200-207.
[5]	Cordoba G, Siersma V, Lopez-Valcarcel B and al. Prescribing style and variation in antibiotic prescriptions for sore throat: cross-sectional study across six countries. BMC Family Practice 2015; 16: 1-8.
[6]	Elbouti A, Rafai M, Chouaib N and al. Evaluation of antibiotic prescriptions in the Emergency Department of the Military Hospital of Instruction Mohammed V (HMIMV). Pan Afr Med J 2016; 25: 162.
[7]	Anna Machowska and Cecilia Stålsby Lundborg. Drivers of Irrational Use of Antibiotics in Europe. Int. J. Environ. Res. Public Health 2019; 16: 27.
[8]	Spoorenberg V, Geerlings SE, Geskus RB and al. Appropriate antibiotic use for patients with complicated urinary tract infections in 38 Dutch Hospital Departments: a retrospective study of variation and determinants. BMC Infectious Diseases 2015; 15: 505.
[9]	McKay R, Mah A, Law MR and al. Systematic Review of Factors Associated with Antibiotic Prescribing for Respiratory Tract Infections. Antimicrob Agents Chemother 2016; 60: 18-4106.
[10]	National Center for Disease Control in India. National Treatment Guidelines of India for the Use of Antimicrobials in Infectious Diseases. Version 1.0. New Delhi, 2016: 1-64.
[11]	Déguénonvo LF, Diallo MOS, Badiane NMD and al. Evaluation of the quality of the antibiotic prescription at the Fann CHNU Emergency Reception Service in Dakar. Méd. et maladies infect 2013; 43: 78.
[12]	Coulibaly Y, Konate A, Kone D and Bougoudogo F. Study of the prescription of antibiotics in Malian hospital. Rev Malienne d’Infectiologie Microbiol 2014; 3: 2‑8.
[13]	Dial NM, Ismail YZ, Lakhe NA and al. Evaluation of the Quality of Prescription of Antibiotics with Curative Intent in a Specialized Department in Dakar, Senegal. Arch Infect Dis Ther 2018; 2: 2577-8455.
[14]	Alvarez-Uria G, Zachariah S and Thomas D. High prescription of antimicrobials in a rural district hospital in India. Pharm Pract (Grenade) 2014; 12: 384.
[15]	Biswas M, Roy DN, Tajmim A and al. Prescription antibiotics for outpatients in Bangladesh: a cross-sectional health survey conducted in three cities. Annals of Clinical Microbiology and Antimicrobials 2014; 13: 15.
[16]	WHO Policy Perspectives on Medicines. Promote the rational use of medicines: essential components. Geneva: World Health Organization; 2002; 6.
[17]	Alemayehu GA, Gonfa R and Tadesse T. Evaluation of Antibiotic Use in Medical Ward of Fitche District Hospital, North Showa Zone, Oromia Region, Ethiopia. Adv Pharmacoepidemiol Drug Saf; 2017; 6: 2167-1052.
[18]	Affolabi D, Alidjinou KE, Dossou-Gbété L and al. Assessment of antibiotics prescribing for outpatients in Cotonou, Benin. Bull Soc Pathol Exot 2009; 102: 110-112.
[19]	Kumar R, Indira K, Rizvi A and al. Antibiotic prescribing practices in primary and secondary health care facilities in Uttar Pradesh, India. J Clin Pharm Ther 2008; 33: 625-3.

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APA Style

Salifou Talassone Bangoura, Abdoulaye Toure, Sidikiba Sidibé, Alioune Camara, Djibril Sylla, et al. (2020). Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea). Central African Journal of Public Health, 6(1), 1-4. https://doi.org/10.11648/j.cajph.20200601.11

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ACS Style

Salifou Talassone Bangoura; Abdoulaye Toure; Sidikiba Sidibé; Alioune Camara; Djibril Sylla, et al. Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea). Cent. Afr. J. Public Health 2020, 6(1), 1-4. doi: 10.11648/j.cajph.20200601.11

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AMA Style

Salifou Talassone Bangoura, Abdoulaye Toure, Sidikiba Sidibé, Alioune Camara, Djibril Sylla, et al. Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea). Cent Afr J Public Health. 2020;6(1):1-4. doi: 10.11648/j.cajph.20200601.11

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@article{10.11648/j.cajph.20200601.11,
  author = {Salifou Talassone Bangoura and Abdoulaye Toure and Sidikiba Sidibé and Alioune Camara and Djibril Sylla and Alpha-Kabinet Keita and Mamadou Saliou Sow and Alimou Camara and Mamadou Saliou Kalifa Diallo and Mohamed Cisse},
  title = {Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea)},
  journal = {Central African Journal of Public Health},
  volume = {6},
  number = {1},
  pages = {1-4},
  doi = {10.11648/j.cajph.20200601.11},
  url = {https://doi.org/10.11648/j.cajph.20200601.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20200601.11},
  abstract = {Background: In hospitals, antibiotics are one of the most prescribed drug classes. The purpose of this study was to describe the extent and factors associated with the prescription of antibiotics in the Internal Medicine Department of Donka National Hospital. Material and Methods: A cross-sectional study was conducted from July 30, 2018 to January 31, 2019 among prescribers and patients hospitalized or seen on an outpatient basis. Data were collected by direct interview and through patient records. A multivariate logistic regression was performed to identify the factors associated with antibiotic prescribing. Results: Out of a total of 400 consultants, 82 (21%) patients received antibiotic therapy. Beta-lactam antibiotics were the most prescribed antibiotic (45%) and urogenital infections (24.3%) were the most common indication. In univariate analysis, the consultation by a trainee physician [OR = 3.06 (95% CI: 1.56-6)] was associated with a prescription for antibiotics. Students/students [OR = 1.85 (95% CI: 1.01-3.39)], civil servants [OR = 1.82 (95% CI: 1.02-3.26)], patients residing in Conakry [OR = 2.06 (95% CI: 1.08-3.91)], those hospitalized [OR = 3.16 (95% CI: 1.55-6.46)] and those with a fever [OR = 6.49 (95% CI: 3.84-10.96)] were more likely to receive an antibiotic. Only fever [OR adjusted = 4.30 (95% CI: 2.43-7.61)] remained associated with the prescription of antibiotics in multivariate analysis. Conclusion: The results showed that fever was the factor independently associated with the antibiotic prescription. In a country where malaria is the main cause of fever, the results suggest the need for training health care workers in antibiotic prescribing.},
 year = {2020}
}

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TY  - JOUR
T1  - Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea)
AU  - Salifou Talassone Bangoura
AU  - Abdoulaye Toure
AU  - Sidikiba Sidibé
AU  - Alioune Camara
AU  - Djibril Sylla
AU  - Alpha-Kabinet Keita
AU  - Mamadou Saliou Sow
AU  - Alimou Camara
AU  - Mamadou Saliou Kalifa Diallo
AU  - Mohamed Cisse
Y1  - 2020/01/06
PY  - 2020
N1  - https://doi.org/10.11648/j.cajph.20200601.11
DO  - 10.11648/j.cajph.20200601.11
T2  - Central African Journal of Public Health
JF  - Central African Journal of Public Health
JO  - Central African Journal of Public Health
SP  - 1
EP  - 4
PB  - Science Publishing Group
SN  - 2575-5781
UR  - https://doi.org/10.11648/j.cajph.20200601.11
AB  - Background: In hospitals, antibiotics are one of the most prescribed drug classes. The purpose of this study was to describe the extent and factors associated with the prescription of antibiotics in the Internal Medicine Department of Donka National Hospital. Material and Methods: A cross-sectional study was conducted from July 30, 2018 to January 31, 2019 among prescribers and patients hospitalized or seen on an outpatient basis. Data were collected by direct interview and through patient records. A multivariate logistic regression was performed to identify the factors associated with antibiotic prescribing. Results: Out of a total of 400 consultants, 82 (21%) patients received antibiotic therapy. Beta-lactam antibiotics were the most prescribed antibiotic (45%) and urogenital infections (24.3%) were the most common indication. In univariate analysis, the consultation by a trainee physician [OR = 3.06 (95% CI: 1.56-6)] was associated with a prescription for antibiotics. Students/students [OR = 1.85 (95% CI: 1.01-3.39)], civil servants [OR = 1.82 (95% CI: 1.02-3.26)], patients residing in Conakry [OR = 2.06 (95% CI: 1.08-3.91)], those hospitalized [OR = 3.16 (95% CI: 1.55-6.46)] and those with a fever [OR = 6.49 (95% CI: 3.84-10.96)] were more likely to receive an antibiotic. Only fever [OR adjusted = 4.30 (95% CI: 2.43-7.61)] remained associated with the prescription of antibiotics in multivariate analysis. Conclusion: The results showed that fever was the factor independently associated with the antibiotic prescription. In a country where malaria is the main cause of fever, the results suggest the need for training health care workers in antibiotic prescribing.
VL  - 6
IS  - 1
ER  -

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Author Information

Salifou Talassone Bangoura

Department of Public Health, Gamal Abdel Nasser University of Conakry, Conakry, Guinea
Abdoulaye Toure

Department of Public Health, Gamal Abdel Nasser University of Conakry, Conakry, Guinea
Sidikiba Sidibé

Department of Public Health, Gamal Abdel Nasser University of Conakry, Conakry, Guinea
Alioune Camara

Department of Public Health, Gamal Abdel Nasser University of Conakry, Conakry, Guinea
Djibril Sylla

Department of Internal Medicine, Donka National Hospital, Conakry, Guinea
Alpha-Kabinet Keita

Guinean Research Center and Training in Infectiology (CERFIG), Gamal Abdel Nasser University of Conakry, Conakry, Guinea
Mamadou Saliou Sow

Guinean Research Center and Training in Infectiology (CERFIG), Gamal Abdel Nasser University of Conakry, Conakry, Guinea
Alimou Camara

Department of Pharmaceutical and Biological Sciences, Gamal Abdel Nasser University of Conakry, Conakry, Guinea
Mamadou Saliou Kalifa Diallo

Guinean Research Center and Training in Infectiology (CERFIG), Gamal Abdel Nasser University of Conakry, Conakry, Guinea
Mohamed Cisse

Department of Dermatology and Venerology, Donka National Hospital, Conakry, Guinea

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APA Style

Salifou Talassone Bangoura, Abdoulaye Toure, Sidikiba Sidibé, Alioune Camara, Djibril Sylla, et al. (2020). Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea). Central African Journal of Public Health, 6(1), 1-4. https://doi.org/10.11648/j.cajph.20200601.11

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ACS Style

Salifou Talassone Bangoura; Abdoulaye Toure; Sidikiba Sidibé; Alioune Camara; Djibril Sylla, et al. Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea). Cent. Afr. J. Public Health 2020, 6(1), 1-4. doi: 10.11648/j.cajph.20200601.11

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AMA Style

Salifou Talassone Bangoura, Abdoulaye Toure, Sidikiba Sidibé, Alioune Camara, Djibril Sylla, et al. Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea). Cent Afr J Public Health. 2020;6(1):1-4. doi: 10.11648/j.cajph.20200601.11

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@article{10.11648/j.cajph.20200601.11,
  author = {Salifou Talassone Bangoura and Abdoulaye Toure and Sidikiba Sidibé and Alioune Camara and Djibril Sylla and Alpha-Kabinet Keita and Mamadou Saliou Sow and Alimou Camara and Mamadou Saliou Kalifa Diallo and Mohamed Cisse},
  title = {Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea)},
  journal = {Central African Journal of Public Health},
  volume = {6},
  number = {1},
  pages = {1-4},
  doi = {10.11648/j.cajph.20200601.11},
  url = {https://doi.org/10.11648/j.cajph.20200601.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20200601.11},
  abstract = {Background: In hospitals, antibiotics are one of the most prescribed drug classes. The purpose of this study was to describe the extent and factors associated with the prescription of antibiotics in the Internal Medicine Department of Donka National Hospital. Material and Methods: A cross-sectional study was conducted from July 30, 2018 to January 31, 2019 among prescribers and patients hospitalized or seen on an outpatient basis. Data were collected by direct interview and through patient records. A multivariate logistic regression was performed to identify the factors associated with antibiotic prescribing. Results: Out of a total of 400 consultants, 82 (21%) patients received antibiotic therapy. Beta-lactam antibiotics were the most prescribed antibiotic (45%) and urogenital infections (24.3%) were the most common indication. In univariate analysis, the consultation by a trainee physician [OR = 3.06 (95% CI: 1.56-6)] was associated with a prescription for antibiotics. Students/students [OR = 1.85 (95% CI: 1.01-3.39)], civil servants [OR = 1.82 (95% CI: 1.02-3.26)], patients residing in Conakry [OR = 2.06 (95% CI: 1.08-3.91)], those hospitalized [OR = 3.16 (95% CI: 1.55-6.46)] and those with a fever [OR = 6.49 (95% CI: 3.84-10.96)] were more likely to receive an antibiotic. Only fever [OR adjusted = 4.30 (95% CI: 2.43-7.61)] remained associated with the prescription of antibiotics in multivariate analysis. Conclusion: The results showed that fever was the factor independently associated with the antibiotic prescription. In a country where malaria is the main cause of fever, the results suggest the need for training health care workers in antibiotic prescribing.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Frequency and Determinants of Prescribing Antibiotics for Internal Medicine at Donka National Hospital (Guinea)
AU  - Salifou Talassone Bangoura
AU  - Abdoulaye Toure
AU  - Sidikiba Sidibé
AU  - Alioune Camara
AU  - Djibril Sylla
AU  - Alpha-Kabinet Keita
AU  - Mamadou Saliou Sow
AU  - Alimou Camara
AU  - Mamadou Saliou Kalifa Diallo
AU  - Mohamed Cisse
Y1  - 2020/01/06
PY  - 2020
N1  - https://doi.org/10.11648/j.cajph.20200601.11
DO  - 10.11648/j.cajph.20200601.11
T2  - Central African Journal of Public Health
JF  - Central African Journal of Public Health
JO  - Central African Journal of Public Health
SP  - 1
EP  - 4
PB  - Science Publishing Group
SN  - 2575-5781
UR  - https://doi.org/10.11648/j.cajph.20200601.11
AB  - Background: In hospitals, antibiotics are one of the most prescribed drug classes. The purpose of this study was to describe the extent and factors associated with the prescription of antibiotics in the Internal Medicine Department of Donka National Hospital. Material and Methods: A cross-sectional study was conducted from July 30, 2018 to January 31, 2019 among prescribers and patients hospitalized or seen on an outpatient basis. Data were collected by direct interview and through patient records. A multivariate logistic regression was performed to identify the factors associated with antibiotic prescribing. Results: Out of a total of 400 consultants, 82 (21%) patients received antibiotic therapy. Beta-lactam antibiotics were the most prescribed antibiotic (45%) and urogenital infections (24.3%) were the most common indication. In univariate analysis, the consultation by a trainee physician [OR = 3.06 (95% CI: 1.56-6)] was associated with a prescription for antibiotics. Students/students [OR = 1.85 (95% CI: 1.01-3.39)], civil servants [OR = 1.82 (95% CI: 1.02-3.26)], patients residing in Conakry [OR = 2.06 (95% CI: 1.08-3.91)], those hospitalized [OR = 3.16 (95% CI: 1.55-6.46)] and those with a fever [OR = 6.49 (95% CI: 3.84-10.96)] were more likely to receive an antibiotic. Only fever [OR adjusted = 4.30 (95% CI: 2.43-7.61)] remained associated with the prescription of antibiotics in multivariate analysis. Conclusion: The results showed that fever was the factor independently associated with the antibiotic prescription. In a country where malaria is the main cause of fever, the results suggest the need for training health care workers in antibiotic prescribing.
VL  - 6
IS  - 1
ER  -

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