| Peer-Reviewed

Practices About Antibiotic Use Among Urban Residents: A Cross-Sectional Survey in Rufisque, Senegal

Received: 17 November 2018    Accepted: 3 December 2018    Published: 21 January 2019
Views:       Downloads:
Abstract

Antibiotics have saved millions of lives around the world. However, their effectiveness is compromised by the emergence and spread of antibiotic resistance. The latter is a threat to global health. Under the International Health Regulations, a national self-assessment was conducted in Senegal to assess the country's capacity to cope with this scourge. It is followed by the joint external evaluation of the World Health Organization. One of the main recommendations is raising public awareness about the rational use of antibiotics. The goal of this study was to evaluate the general public's practices regarding antibiotics and the determinants of antibiotic use without a medical prescription. The study was cross-sectional. It was conducted at the Rufisque bus station. Rufisque is a city located in the region of Dakar, capital of Senegal. We estimated the sample size using Raosoft. Participants were selected according to a convenience sampling. A questionnaire was administered in an individual interview. Logistic regression was used to identify the determinants of antibiotic use without a prescription. A total of 400 people were included. Among them, 75% (300/400) said they had taken antibiotics during the last twelve months. The sources of supply were the community pharmacy (81%), the entourage (12%), the remaining antibiotics (5%) and the illicit drugs market (2%). The use of antibiotics without a prescription was reported by 75% of participants (225/300). It was more common among the uneducated people (OR = 2.7, P =.002). In addition, 16.8% (67/400) said they had shared their antibiotic treatment with their relatives or friends. Shortening the duration and frequency of antibiotic treatment was found in 65.8% (263/400) and 29.3% (117/400) of respondents, respectively. About 7% (29/400) said they sometimes demand antibiotics to prescribers. Almost all (98.8%, 395/400) stated that they had never returned unwanted medicines to pharmacies or health facilities while 37.8% (151/400) said they had never checked the expiry dates of medicines. This study, conducted in an urban setting, showed that respondents have recourse to inadequate practices toward antibiotics. We recommend the sensitization of populations especially those who are not educated. Other studies should be conducted mainly in rural areas to identify the most commonly used antibiotics and the extent of inappropriate practices and their determinants.

Published in Central African Journal of Public Health (Volume 5, Issue 1)
DOI 10.11648/j.cajph.20190501.11
Page(s) 1-12
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Practices, General Public; Antibiotic Use, Antibiotic Resistance, Rufisque, Senegal

References
[1] Mohr KI. History of Antibiotics Research. Curr Top Microbiol Immunol. 2016; 398: 237-272. doi: 10.1007/82_2016_499. Review. PubMed PMID: 27738915.
[2] Ventola CL. The antibiotic resistance crisis: part 1: causes and threats. P T. 2015 Apr; 40 (4): 277-83. PubMed PMID: 25859123; PubMed Central PMCID: PMC4378521.
[3] Mason T, Trochez C, Thomas R, Babar M, Hesso I, Kayyali R. Knowledge and awareness of the general public and perception of pharmacists about antibiotic resistance. BMC Public Health. 2018 Jun 8; 18 (1): 711. doi: 10.1186/s12889-018-5614-3. PubMed PMID: 29884154; PubMed Central PMCID: PMC5994078.
[4] Knufmann-Happe K. Réponses politiques à la résistance aux antimicrobiens – la stratégie allemande. In AMR Control. Surmonter La Résistance Aux Antimicrobiens, 3rd ed.; WAAAR; Global Health Dynamics: Suffolk, UK, 2017; Volume 1, pp. 16–20. ISBN 978-0-9576072-7-9. Available online: http://resistancecontrol.info/wp-content/uploads/2018/05/16-20.pdf (accessed on 16 October 2018).
[5] Ayukekbong JA, Ntemgwa M, Atabe AN. The threat of antimicrobial resistance in developing countries: causes and control strategies. Antimicrob Resist Infect Control. 2017 May 15; 6: 47. doi: 10.1186/s13756-017-0208-x. eCollection 2017. Review. PubMed PMID: 28515903; PubMed Central PMCID: PMC5433038.
[6] The World Alliance Against Antibiotic Resistance (WAAAR). AMR Control in discussion with Dr Marc Sprenger. In AMR Control 2018. Overcoming Global Antimicrobial Resistance; WAAAR; Global Health Dynamics: Suffolk, UK, 2018; pp. 10–12. ISBN 978-0-9576072-7-9. Available online: http://resistancecontrol.info/wp-content/uploads/2018/08/10-12.pdf (accessed on 1 November 2018).
[7] Organisation Mondiale de la Santé. Plan D’action Mondial Pour Combattre la Résistance Aux Antimicrobiens; OMS: Généve, Suisse, 2016. Available online: http://apps.who.int/iris/bitstream/handle/10665/249548/9789242509762fre.pdf;jsessionid=6BA7B094CA69BC758FC52F00A7E179E0?sequence=1 (accessed on 10 October 2018).
[8] O’Neill, J. Tackling Drug-Resistant Infections Globally: Final Report and Recommendations. Review on Antimicrobial Resistance. Wellcome Trust and HM Government 2016. Available online: https://amr-review.org/sites/default/files/160525_Final%20paper_with%20cover.pdf (accessed on 16 October 2018).
[9] World Health Organization. Global Antimicrobial Resistance Surveillance System (GLASS) Report: Early implementation 2016-2017. WHO: Geneva, Switzerland, 2017. Licence: CC BY-NC-SA 3.0 IGO; 2017. ISBN 978-92-4-151344-9. Available online: http://apps.who.int/iris/bitstream/handle/10665/259744/9789241513449-eng.pdf?sequence=1 (accessed on 16 October 2018).
[10] World Health Organization. Antimicrobial Resistance: Global Report on Surveillance. WHO: Geneva, Switzerland, 2014. ISBN 978 92 4 156474 8. Available online: http://apps.who.int/iris/bitstream/handle/10665/112642/9789241564748_eng.pdf?sequence=1&isAllowed=y (accessed on 18 October 2018).
[11] Richter SE, Miller L, Uslan DZ, Bell D, Watson K, Humphries R, McKinnell JA. Risk Factors for Colistin Resistance among Gram-Negative Rods and Klebsiella pneumoniae Isolates. J Clin Microbiol. 2018 Aug 27; 56 (9). pii: e00149-18. doi: 10.1128/JCM.00149-18. Print 2018 Sep. PubMed PMID: 29976595; PubMed Central PMCID: PMC6113453.
[12] Liu YY, Wang Y, Walsh TR, Yi LX, Zhang R, Spencer J, et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infect Dis. 2016 Feb; 16 (2): 161-8. doi: 10.1016/S1473-3099(15)00424-7. Epub 2015 Nov 19. PubMed PMID: 26603172.
[13] Camara M, Mane MT, Ba-Diallo A., Dieng A, Diop-Ndiaye H, Karam F, et al. Extended-spectrum beta-lactamase- and carbapenemase-producing Enterobacteriaceae clinical isolates in a Senegalese teaching hospital: A cross sectional study. Afr J Microbiol Res. 2017 Nov 28; 11 (44): 1600-1605. DOI: 10.5897/AJMR2017.8716.
[14] World Bank Group. Drug-Resistant Infections: A Threat to Our Economic Future; Final Report; WBG: Washington, DC, USA, 2017. Available online: http://documents.worldbank.org/curated/en/%20323311493396993758/pdf/114679-REVISED-v2-Drug-Resistant-Infections-Final-Report.pdf (accessed on 16 October 2018).
[15] Carlet J; members of the WAAAR. World Alliance Against Antibiotic Resistance: The WAAAR declaration against antibiotic resistance. Med Intensiva. 2015 Jan-Feb; 39 (1): 34-9. doi: 10.1016/j.medin.2014.10.004. Epub 2014 Dec 17. PubMed PMID: 25534919.
[16] World Alliance Against Anrtibiotic Resistance. AMR Control. Available online: http://resistancecontrol.info/ (accessed on 20 October 2018).
[17] Coll-Seck, A. M.; Seck, I.; Sow, A. I.; Ndoye, B.; Ngom, B.; Diack, P. A. La gouvernance contre la résistance aux antimicrobiens en Afrique: Faire face quand les ressources sont limitées—L’exemple du Sénégal. In AMR Control. Surmonter La Résistance Aux Antimicrobiens, 3rd ed.; WAAAR; Global Health Dynamics: Suffolk, UK, 2017; Volume 1, pp. 10–15. ISBN 978-0-9576072-7-9. Available online: http://resistancecontrol.info/wp-content/uploads/2018/05/10-15.pdf (accessed on 20 September 2018).
[18] Organisation Mondiale de la santé. Évaluation Externe Conjointe des Principales Capacités RSI de la République du Sénégal; Rapport de Mission: 28 Novembre–2 Décembre 2016; OMS: Généve, Suisse, 2017. Available online: http://apps.who.int/iris/bitstream/handle/10665/255765/WHO-WHE-CPI-2017.31-fre.pdf?sequence=1 (accessed on 19 September 2018).
[19] Agence Nationale de la Statistique et de la Démographie. Projection de la Population de la Région de Dakar, 2013–2025; ANSD: Dakar, Sénégal, 2013. Available online: http://www.ansd.sn/ressources/publications/indicateurs/Projections-demographiques-2013-2025+.htm (accessed on 16 May 2018).
[20] Agence Nationale de la Statistique et de la Démographie et Fonds des Nations Unies pour l’enfance. MICS V Dakar Enquête par Grappes à Indicateurs Multiples 2015–2016; Rapport Final; ANSD: Dakar, Sénégal, 2016. Available online: http://www.ansd.sn/ressources/publications/RAPPORT%20MICS%20Urbaine%20Dakar%202015-2016_FINAL%20novembre_version%20finale%20.pdf (accessed on 17 May 2018).
[21] Raosoft, Inc. Raosoft Sample Size Calculator. 2004. Available online: http://www.raosoft.com/samplesize.html (accessed on 30 October 2017).
[22] Hosmer DWJ, Lemeshow S. Applied Logistic Regression, 2nd ed.; Wiley-Interscience Publication: New York, NY, USA, 2000; p. 392.
[23] A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway. Surg Infect (Larchmt). 2017 Nov/Dec; 18 (8): 846-853. doi: 10.1089/sur.2017.219. PubMed PMID: 29173054.
[24] Awad AI, Aboud EA. Knowledge, attitude and practice towards antibiotic use among the public in Kuwait. PLoS One. 2015 Feb 12; 10 (2): e0117910. doi: 10.1371/journal.pone.0117910. eCollection 2015. PubMed PMID: 25675405; PubMed Central PMCID: PMC4326422.
[25] Gebeyehu E, Bantie L, Azage M. Inappropriate Use of Antibiotics and Its Associated Factors among Urban and Rural Communities of Bahir Dar City Administration, Northwest Ethiopia. PLoS One. 2015 Sep 17; 10 (9): e0138179. doi: 10.1371/journal.pone.0138179. eCollection 2015. PubMed PMID: 26379031; PubMed Central PMCID: PMC4574735.
[26] Zajmi D, Berisha M, Begolli I, Hoxha R, Mehmeti R, Mulliqi-Osmani G, et al. Public knowledge, attitudes and practices regarding antibiotic use in Kosovo. Pharm Pract (Granada). 2017 Jan-Mar; 15 (1): 827. doi: 10.18549/PharmPract.2017.01.827. Epub 2017 Mar 15. PubMed PMID: 28503216; PubMed Central PMCID: PMC5386617.
[27] Klein EY, Van Boeckel TP, Martinez EM, Pant S, Gandra S, Levin SA, et al. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proc Natl Acad Sci U S A. 2018 Apr 10; 115 (15): E3463-E3470. doi: 10.1073/pnas.1717295115. Epub 2018 Mar 26. PubMed PMID: 29581252; PubMed Central PMCID: PMC5899442.
[28] Hadi MA, Karami NA, Al-Muwalid AS, Al-Otabi A, Al-Subahi E, Bamomen A, et al. Community pharmacists' knowledge, attitude, and practices towards dispensing antibiotics without prescription (DAwP): a cross-sectional survey in Makkah Province, Saudi Arabia. Int J Infect Dis. 2016 Jun; 47: 95-100. doi: 10.1016/j.ijid.2016.06.003. Epub 2016 Jun 22. PubMed PMID: 27343987.
[29] Ouedraogo AS, Jean Pierre H, Bañuls AL, Ouédraogo R, Godreuil, S. Émergence et diffusion de la résistance aux antibiotiques en Afrique de l’Ouest: Facteurs favorisants et évaluation de la menace. Med. Sante Trop. 2017, 27, 147–154.
[30] Ocan M, Obuku EA, Bwanga F, Akena D, Richard S, Ogwal-Okeng J, Obua C. Household antimicrobial self-medication: a systematic review and meta-analysis of the burden, risk factors and outcomes in developing countries. BMC Public Health. 2015 Aug 1; 15: 742. doi: 10.1186/s12889-015-2109-3. Review. PubMed PMID: 26231758; PubMed Central PMCID: PMC4522083.
[31] Nadimpalli M, Delarocque-Astagneau E, Love DC, Price LB, Huynh BT, Collard JM, et al.; Bacterial Infections and antibiotic-Resistant Diseases among Young children in low-income countries (BIRDY) Study Group. Combating Global Antibiotic Resistance: Emerging One Health Concerns in Lower- and Middle-Income Countries. Clin Infect Dis. 2018 Mar 5; 66 (6): 963-969. doi: 10.1093/cid/cix879. PubMed PMID: 29346620.
[32] Bloom G, Merrett GB, Wilkinson A, Lin V, Paulin S. Antimicrobial resistance and universal health coverage. BMJ Glob Health. 2017 Oct 31; 2 (4): e000518. doi: 10.1136/bmjgh-2017-000518. eCollection 2017. Review. PubMed PMID: 29225955; PubMed Central PMCID: PMC5717966.
[33] Salm F, Ernsting C, Kuhlmey A, Kanzler M, Gastmeier P, Gellert P. Antibiotic use, knowledge and health literacy among the general population in Berlin, Germany and its surrounding rural areas. PLoS One. 2018 Feb 23; 13 (2): e0193336. doi: 10.1371/journal.pone.0193336. eCollection 2018. PubMed PMID: 29474470; PubMed Central PMCID: PMC5825110.
[34] Ocan M, Bbosa GS, Waako P, Ogwal-Okeng J, Obua C. Factors predicting home storage of medicines in Northern Uganda. BMC Public Health. 2014 Jun 26; 14: 650. doi: 10.1186/1471-2458-14-650. PubMed PMID: 24964746; PubMed Central PMCID: PMC4229978.
[35] Wang X, Lin L, Xuan Z, Li L, Zhou X. Keeping Antibiotics at Home Promotes Self-Medication with Antibiotics among Chinese University Students. Int J Environ Res Public Health. 2018 Apr 5; 15 (4). pii: E687. doi: 10.3390/ijerph15040687. PubMed PMID: 29621165; PubMed Central PMCID: PMC5923729.
[36] Togoobaatar G, Ikeda N, Ali M, Sonomjamts M, Dashdemberel S, Mori R, et al. Survey of non-prescribed use of antibiotics for children in an urban community in Mongolia. Bull World Health Organ. 2010 Dec 1; 88 (12): 930–936. doi: 10.2471/BLT.10.079004.
[37] Mouhieddine TH, Olleik Z, Itani MM, Kawtharani S, Nassar H, Hassoun R, et al. Assessing the Lebanese population for their knowledge, attitudes and practices of antibiotic usage. J Infect Public Health. 2015 Jan-Feb; 8 (1): 20-31. doi: 10.1016/j.jiph.2014.07.010. Epub 2014 Aug 22. PubMed PMID: 25154919.
[38] Ogunshe A, Adinmonyema P. Evaluation of bacteriostatic potency of expired oral paediatric antibiotics and implications on infant health. Pan Afr Med J. 2014 Dec 15; 19: 378. doi: 10.11604/pamj.2014.19.378.2156.
[39] Ayalew MB. Self-medication practice in Ethiopia: a systematic review. Patient Prefer Adherence. 2017 Mar 1; 11: 401-413. doi: 10.2147/PPA.S131496. eCollection 2017. Review. PubMed PMID: 28280312; PubMed Central PMCID: PMC5338978.
Cite This Article
  • APA Style

    Oumar Bassoum, Mamadou Makhtar Mbacke Lèye, Ndèye Marème Sougou, Mayassine Diongue, Khadim Niang, et al. (2019). Practices About Antibiotic Use Among Urban Residents: A Cross-Sectional Survey in Rufisque, Senegal. Central African Journal of Public Health, 5(1), 1-12. https://doi.org/10.11648/j.cajph.20190501.11

    Copy | Download

    ACS Style

    Oumar Bassoum; Mamadou Makhtar Mbacke Lèye; Ndèye Marème Sougou; Mayassine Diongue; Khadim Niang, et al. Practices About Antibiotic Use Among Urban Residents: A Cross-Sectional Survey in Rufisque, Senegal. Cent. Afr. J. Public Health 2019, 5(1), 1-12. doi: 10.11648/j.cajph.20190501.11

    Copy | Download

    AMA Style

    Oumar Bassoum, Mamadou Makhtar Mbacke Lèye, Ndèye Marème Sougou, Mayassine Diongue, Khadim Niang, et al. Practices About Antibiotic Use Among Urban Residents: A Cross-Sectional Survey in Rufisque, Senegal. Cent Afr J Public Health. 2019;5(1):1-12. doi: 10.11648/j.cajph.20190501.11

    Copy | Download

  • @article{10.11648/j.cajph.20190501.11,
      author = {Oumar Bassoum and Mamadou Makhtar Mbacke Lèye and Ndèye Marème Sougou and Mayassine Diongue and Khadim Niang and Jean Augustin Diegane Tine and Mouhamad Mbodji and Adama Faye and Ibrahima Seck and Djibril Fall and Anta Tal-Dia},
      title = {Practices About Antibiotic Use Among Urban Residents: A Cross-Sectional Survey in Rufisque, Senegal},
      journal = {Central African Journal of Public Health},
      volume = {5},
      number = {1},
      pages = {1-12},
      doi = {10.11648/j.cajph.20190501.11},
      url = {https://doi.org/10.11648/j.cajph.20190501.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cajph.20190501.11},
      abstract = {Antibiotics have saved millions of lives around the world. However, their effectiveness is compromised by the emergence and spread of antibiotic resistance. The latter is a threat to global health. Under the International Health Regulations, a national self-assessment was conducted in Senegal to assess the country's capacity to cope with this scourge. It is followed by the joint external evaluation of the World Health Organization. One of the main recommendations is raising public awareness about the rational use of antibiotics. The goal of this study was to evaluate the general public's practices regarding antibiotics and the determinants of antibiotic use without a medical prescription. The study was cross-sectional. It was conducted at the Rufisque bus station. Rufisque is a city located in the region of Dakar, capital of Senegal. We estimated the sample size using Raosoft. Participants were selected according to a convenience sampling. A questionnaire was administered in an individual interview. Logistic regression was used to identify the determinants of antibiotic use without a prescription. A total of 400 people were included. Among them, 75% (300/400) said they had taken antibiotics during the last twelve months. The sources of supply were the community pharmacy (81%), the entourage (12%), the remaining antibiotics (5%) and the illicit drugs market (2%). The use of antibiotics without a prescription was reported by 75% of participants (225/300). It was more common among the uneducated people (OR = 2.7, P =.002). In addition, 16.8% (67/400) said they had shared their antibiotic treatment with their relatives or friends. Shortening the duration and frequency of antibiotic treatment was found in 65.8% (263/400) and 29.3% (117/400) of respondents, respectively. About 7% (29/400) said they sometimes demand antibiotics to prescribers. Almost all (98.8%, 395/400) stated that they had never returned unwanted medicines to pharmacies or health facilities while 37.8% (151/400) said they had never checked the expiry dates of medicines. This study, conducted in an urban setting, showed that respondents have recourse to inadequate practices toward antibiotics. We recommend the sensitization of populations especially those who are not educated. Other studies should be conducted mainly in rural areas to identify the most commonly used antibiotics and the extent of inappropriate practices and their determinants.},
     year = {2019}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Practices About Antibiotic Use Among Urban Residents: A Cross-Sectional Survey in Rufisque, Senegal
    AU  - Oumar Bassoum
    AU  - Mamadou Makhtar Mbacke Lèye
    AU  - Ndèye Marème Sougou
    AU  - Mayassine Diongue
    AU  - Khadim Niang
    AU  - Jean Augustin Diegane Tine
    AU  - Mouhamad Mbodji
    AU  - Adama Faye
    AU  - Ibrahima Seck
    AU  - Djibril Fall
    AU  - Anta Tal-Dia
    Y1  - 2019/01/21
    PY  - 2019
    N1  - https://doi.org/10.11648/j.cajph.20190501.11
    DO  - 10.11648/j.cajph.20190501.11
    T2  - Central African Journal of Public Health
    JF  - Central African Journal of Public Health
    JO  - Central African Journal of Public Health
    SP  - 1
    EP  - 12
    PB  - Science Publishing Group
    SN  - 2575-5781
    UR  - https://doi.org/10.11648/j.cajph.20190501.11
    AB  - Antibiotics have saved millions of lives around the world. However, their effectiveness is compromised by the emergence and spread of antibiotic resistance. The latter is a threat to global health. Under the International Health Regulations, a national self-assessment was conducted in Senegal to assess the country's capacity to cope with this scourge. It is followed by the joint external evaluation of the World Health Organization. One of the main recommendations is raising public awareness about the rational use of antibiotics. The goal of this study was to evaluate the general public's practices regarding antibiotics and the determinants of antibiotic use without a medical prescription. The study was cross-sectional. It was conducted at the Rufisque bus station. Rufisque is a city located in the region of Dakar, capital of Senegal. We estimated the sample size using Raosoft. Participants were selected according to a convenience sampling. A questionnaire was administered in an individual interview. Logistic regression was used to identify the determinants of antibiotic use without a prescription. A total of 400 people were included. Among them, 75% (300/400) said they had taken antibiotics during the last twelve months. The sources of supply were the community pharmacy (81%), the entourage (12%), the remaining antibiotics (5%) and the illicit drugs market (2%). The use of antibiotics without a prescription was reported by 75% of participants (225/300). It was more common among the uneducated people (OR = 2.7, P =.002). In addition, 16.8% (67/400) said they had shared their antibiotic treatment with their relatives or friends. Shortening the duration and frequency of antibiotic treatment was found in 65.8% (263/400) and 29.3% (117/400) of respondents, respectively. About 7% (29/400) said they sometimes demand antibiotics to prescribers. Almost all (98.8%, 395/400) stated that they had never returned unwanted medicines to pharmacies or health facilities while 37.8% (151/400) said they had never checked the expiry dates of medicines. This study, conducted in an urban setting, showed that respondents have recourse to inadequate practices toward antibiotics. We recommend the sensitization of populations especially those who are not educated. Other studies should be conducted mainly in rural areas to identify the most commonly used antibiotics and the extent of inappropriate practices and their determinants.
    VL  - 5
    IS  - 1
    ER  - 

    Copy | Download

Author Information
  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Laboratory of Therapeutic and Organic Chemistry, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Laboratory of Therapeutic and Organic Chemistry, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal

  • Department of Public Health and Preventive Medicine, Faculty of Medicine, Pharmacy and Odontology, University Cheikh Anta Diop, Dakar, Senegal; Institute of Health and Development, University Cheikh Anta Diop, Dakar, Senegal

  • Sections