Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report

Enow-Orock George Enownchong; Eyongeta Divine Enow

doi:doi:10.11648/j.ijhpebs.20160201.11

| Peer-Reviewed

Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report

Enow-Orock George Enownchong, Eyongeta Divine Enow

Published in International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 2, Issue 1)

Received: 30 March 2016 Accepted: 6 April 2016 Published: 17 May 2016

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Malignant tumours of the kidney are rare. Some of these tumours have been associated with AIDS. Renal transitional cell carcinoma is not only rare, but has been rarely reported as an associated AIDS lesion. We report the case of a multifocal, unilateral, renal transitional cell carcinoma found in an acquired cystic,nephrolithiasic, non-functional kidney in an AIDS patient on combined Anti RetroviralTherapy (cART) for 10 years. This case clearly illustrates the transition from a physical lesion (renal calculi) through a dystrophic condition (cystic kidney) to malignant transformation (transitional carcinoma) in a background of immune depression (AIDS) and cART. It is not clear if the immune depression is a risk factor for the tumour. The interaction between the conditions was not investigated in this report. Further studies are required to document the relationship between cystic degeneration, AIDS, cART and progression to transitional cell carcinoma of the kidney, as seen in this case.

Published in	International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 2, Issue 1)
DOI	10.11648/j.ijhpebs.20160201.11
Page(s)	1-3
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

HIV, AIDS, cART, Transitional Cell, Carcinoma, Kidney

References

[1]	Hubert F, Ozzard A, Tuthill M, Bower M. HIV-associated renal cancer. J HIV Ther 2007, 12(3): 74-74.
[2]	Powles T, Bower M, Daugaard G et al. Multicenter study of human immunodeficiency virus-related germ cell tumors. J Clin Oncol, 2003, 21, 1922-1927.
[3]	Frisch M, Biggar RJ, Engels EA, Goedert JJ. Association of cancer with AIDS-related immunosuppression in adults. J Am Med Assoc, 2001, 285, 1736-1745.
[4]	Gallagher B, Wang Z, Schymura MJ et al. Cancer incidence in New York State acquired immunodeficiency syndrome patients. Am J Epidemiol, 2001, 154, 544-556.
[5]	Grulich AE, Wan X, Law MG et al. Risk of cancer in people with AIDS. AIDS, 1999, 13, 839-843.
[6]	Franceschi S, Dal Maso L, Arniani S et al. Risk of cancer other than Kaposi's sarcoma and non-Hodgkin's lymphoma in persons with AIDS in Italy. Cancer and AIDS Registry Linkage Study. Br J Cancer, 1998, 78, 966-970.
[7]	Baynham SA, Katner HP, Cleveland KB. Increased prevalence of renal cell carcinoma in patients with HIV infection. AIDS Patient Care STD, 1997, 11, 161-165.
[8]	Bleiweiss IJ, Pervez NK, Hammer GS, Dikman SH. Cytomegalovirus-induced adrenal insufficiency and associated renal cell carcinoma in AIDS. Mt Sinai J Med, 1986, 53, 676-679. Azon-Masoliver A, Moreno A, Gatell JM, Mascaro JM. Renal cell adenocarcinoma associated with AIDS-related Kaposi's sarcoma. AIDS, 1990, 4, 818-819.
[9]	Adjiman S, Zerbib M, Flam T et al. Genitourinary tumors and HIV1 infection. EurUrol, 1990, 18, 61-63.
[10]	Verani DA, Badone M, Borella T, Garbaccio G. A renal tumor in a female HIV-positive patient.A case report. Minerva Med, 1990, 81(3 Suppl), 73-75.
[11]	Montserrat V, Muntaner L, Mus A et al. Urologic neoplasms in AIDS. ActaUrolEsp, 1992, 16, 35-38.
[12]	Aghaji AE, Odoemene CA. Renal cell carcinoma in Enugu, Nigeria. West Afr J Med, 2000, 19, 254-258.
[13]	EnowOrock GE, Eyongeta DE, Weledji EP. Tumours of the Kidney in Yaounde, Cameroon. An 8 years population study. Afr J Integ Health 2013, 01: 06-10.
[14]	George Enow Orock Enownchong (2012), IN Anderson Sama Doh (Ed) Paul Ndom. Cancer Incidence and Trends in Yaounde, Cameroon. Sarbrucken: Lambert Academic Publishing ISSN 978-3-659-19027-8.: 63-65.
[15]	Balslev E, Fischer S, Transitional cell carcinoma of the renal collecting tubules (renal urothelioma) 1983. Acta Pathol Microbiol Immunol Scand (A). 91:419-424.
[16]	Colin P, Koenig P, Ouzzane A, Berthon N, Villers A, Biserte J, et al. Environmental factors involved in carcinogenesis of urothelial cell carcinomas of the upper urinary tract. BJU Int. Nov 2009; 104(10):1436-40.
[17]	McDougal WS, Cramer SF, Miller R. Invasive carcinoma of the renal pelvis following cyclophosphamide therapy for non malignant disease. Cancer 1981,48: 691-695
[18]	Hsueh TY, Huang YH, Chiu AW, et al. A comparison of the clinical outcome between open and hand-assisted laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma. BJU Int. Oct 2004; 94(6):798-801.
[19]	Kawauchi A, Fujito A, Ukimura O, et al. Hand assisted retroperitoneoscopic nephroureterectomy: comparison with the open procedure. J Urol. Mar 2003; 169(3):890- 894.

Cite This Article

Plain Text BibTeX RIS

APA Style

Enow-Orock George Enownchong, Eyongeta Divine Enow. (2016). Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 2(1), 1-3. https://doi.org/10.11648/j.ijhpebs.20160201.11

Copy | Download

ACS Style

Enow-Orock George Enownchong; Eyongeta Divine Enow. Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2016, 2(1), 1-3. doi: 10.11648/j.ijhpebs.20160201.11

Copy | Download

AMA Style

Enow-Orock George Enownchong, Eyongeta Divine Enow. Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report. Int J HIV/AIDS Prev Educ Behav Sci. 2016;2(1):1-3. doi: 10.11648/j.ijhpebs.20160201.11

Copy | Download

@article{10.11648/j.ijhpebs.20160201.11,
  author = {Enow-Orock George Enownchong and Eyongeta Divine Enow},
  title = {Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report},
  journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
  volume = {2},
  number = {1},
  pages = {1-3},
  doi = {10.11648/j.ijhpebs.20160201.11},
  url = {https://doi.org/10.11648/j.ijhpebs.20160201.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20160201.11},
  abstract = {Malignant tumours of the kidney are rare. Some of these tumours have been associated with AIDS. Renal transitional cell carcinoma is not only rare, but has been rarely reported as an associated AIDS lesion. We report the case of a multifocal, unilateral, renal transitional cell carcinoma found in an acquired cystic,nephrolithiasic, non-functional kidney in an AIDS patient on combined Anti RetroviralTherapy (cART) for 10 years. This case clearly illustrates the transition from a physical lesion (renal calculi) through a dystrophic condition (cystic kidney) to malignant transformation (transitional carcinoma) in a background of immune depression (AIDS) and cART. It is not clear if the immune depression is a risk factor for the tumour. The interaction between the conditions was not investigated in this report. Further studies are required to document the relationship between cystic degeneration, AIDS, cART and progression to transitional cell carcinoma of the kidney, as seen in this case.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report
AU  - Enow-Orock George Enownchong
AU  - Eyongeta Divine Enow
Y1  - 2016/05/17
PY  - 2016
N1  - https://doi.org/10.11648/j.ijhpebs.20160201.11
DO  - 10.11648/j.ijhpebs.20160201.11
T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
SP  - 1
EP  - 3
PB  - Science Publishing Group
SN  - 2575-5765
UR  - https://doi.org/10.11648/j.ijhpebs.20160201.11
AB  - Malignant tumours of the kidney are rare. Some of these tumours have been associated with AIDS. Renal transitional cell carcinoma is not only rare, but has been rarely reported as an associated AIDS lesion. We report the case of a multifocal, unilateral, renal transitional cell carcinoma found in an acquired cystic,nephrolithiasic, non-functional kidney in an AIDS patient on combined Anti RetroviralTherapy (cART) for 10 years. This case clearly illustrates the transition from a physical lesion (renal calculi) through a dystrophic condition (cystic kidney) to malignant transformation (transitional carcinoma) in a background of immune depression (AIDS) and cART. It is not clear if the immune depression is a risk factor for the tumour. The interaction between the conditions was not investigated in this report. Further studies are required to document the relationship between cystic degeneration, AIDS, cART and progression to transitional cell carcinoma of the kidney, as seen in this case.
VL  - 2
IS  - 1
ER  -

Copy | Download

Author Information

Enow-Orock George Enownchong

Pathology Unit, Regional Hospital Buea, Buea, South West Region, Cameroon
Eyongeta Divine Enow

Urology Unit, Regional Hospital Limbe, Limbe, South West Region, Cameroon

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Enow-Orock George Enownchong, Eyongeta Divine Enow. (2016). Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 2(1), 1-3. https://doi.org/10.11648/j.ijhpebs.20160201.11

Copy | Download

ACS Style

Enow-Orock George Enownchong; Eyongeta Divine Enow. Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2016, 2(1), 1-3. doi: 10.11648/j.ijhpebs.20160201.11

Copy | Download

AMA Style

Enow-Orock George Enownchong, Eyongeta Divine Enow. Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report. Int J HIV/AIDS Prev Educ Behav Sci. 2016;2(1):1-3. doi: 10.11648/j.ijhpebs.20160201.11

Copy | Download

@article{10.11648/j.ijhpebs.20160201.11,
  author = {Enow-Orock George Enownchong and Eyongeta Divine Enow},
  title = {Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report},
  journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
  volume = {2},
  number = {1},
  pages = {1-3},
  doi = {10.11648/j.ijhpebs.20160201.11},
  url = {https://doi.org/10.11648/j.ijhpebs.20160201.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20160201.11},
  abstract = {Malignant tumours of the kidney are rare. Some of these tumours have been associated with AIDS. Renal transitional cell carcinoma is not only rare, but has been rarely reported as an associated AIDS lesion. We report the case of a multifocal, unilateral, renal transitional cell carcinoma found in an acquired cystic,nephrolithiasic, non-functional kidney in an AIDS patient on combined Anti RetroviralTherapy (cART) for 10 years. This case clearly illustrates the transition from a physical lesion (renal calculi) through a dystrophic condition (cystic kidney) to malignant transformation (transitional carcinoma) in a background of immune depression (AIDS) and cART. It is not clear if the immune depression is a risk factor for the tumour. The interaction between the conditions was not investigated in this report. Further studies are required to document the relationship between cystic degeneration, AIDS, cART and progression to transitional cell carcinoma of the kidney, as seen in this case.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - Renal Transitional Cell Carcinoma in an Aids Patient on Long Term Combined Antiretroviral Therapy: Case Report
AU  - Enow-Orock George Enownchong
AU  - Eyongeta Divine Enow
Y1  - 2016/05/17
PY  - 2016
N1  - https://doi.org/10.11648/j.ijhpebs.20160201.11
DO  - 10.11648/j.ijhpebs.20160201.11
T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
SP  - 1
EP  - 3
PB  - Science Publishing Group
SN  - 2575-5765
UR  - https://doi.org/10.11648/j.ijhpebs.20160201.11
AB  - Malignant tumours of the kidney are rare. Some of these tumours have been associated with AIDS. Renal transitional cell carcinoma is not only rare, but has been rarely reported as an associated AIDS lesion. We report the case of a multifocal, unilateral, renal transitional cell carcinoma found in an acquired cystic,nephrolithiasic, non-functional kidney in an AIDS patient on combined Anti RetroviralTherapy (cART) for 10 years. This case clearly illustrates the transition from a physical lesion (renal calculi) through a dystrophic condition (cystic kidney) to malignant transformation (transitional carcinoma) in a background of immune depression (AIDS) and cART. It is not clear if the immune depression is a risk factor for the tumour. The interaction between the conditions was not investigated in this report. Further studies are required to document the relationship between cystic degeneration, AIDS, cART and progression to transitional cell carcinoma of the kidney, as seen in this case.
VL  - 2
IS  - 1
ER  -

Copy | Download